Matthew D Layne - Publications

Affiliations: 
Boston University School of Medicine, Boston, MA 
Area:
biochemistry, fibrosis, ECM, cellular differentiation

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Desevin K, Cortez BN, Lin JZ, Lama D, Layne MD, Farmer SR, Rabhi N. Adrenergic Reprogramming of Preexisting Adipogenic Trajectories Steer Naïve Mural Cells Toward Beige Differentiation. Biorxiv : the Preprint Server For Biology. PMID 37662295 DOI: 10.1101/2023.08.26.554950  0.605
2022 Dance YW, Obenreder MC, Seibel AJ, Meshulam T, Ogony JW, Lahiri N, Pacheco-Spann L, Radisky DC, Layne MD, Farmer SR, Nelson CM, Tien J. Adipose Cells Induce Escape from an Engineered Human Breast Microtumor Independently of their Obesity Status. Cellular and Molecular Bioengineering. 16: 23-39. PMID 36660589 DOI: 10.1007/s12195-022-00750-y  0.532
2022 Rabhi N, Desevin K, Belkina AC, Tilston-Lunel A, Varelas X, Layne MD, Farmer SR. Obesity-induced senescent macrophages activate a fibrotic transcriptional program in adipocyte progenitors. Life Science Alliance. 5. PMID 35181634 DOI: 10.26508/lsa.202101286  0.628
2021 Wang D, Rabhi N, Yet SF, Farmer SR, Layne MD. Aortic carboxypeptidase-like protein regulates vascular adventitial progenitor and fibroblast differentiation through myocardin related transcription factor A. Scientific Reports. 11: 3948. PMID 33597582 DOI: 10.1038/s41598-021-82941-7  0.644
2020 Vishwanath N, Monis WJ, Hoffmann GA, Ramachandran B, DiGiacomo V, Wong JY, Smith ML, Layne MD. Mechanisms of aortic carboxypeptidase-like protein secretion and identification of an intracellularly retained variant associated with Ehlers-Danlos syndrome. The Journal of Biological Chemistry. PMID 32482891 DOI: 10.1074/Jbc.Ra120.013902  0.347
2018 Lee MJ, Pickering RT, Shibad V, Wu Y, Karastergiou K, Jager M, Layne MD, Fried SK. Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis. Diabetes. PMID 30530781 DOI: 10.2337/Db18-0955  0.417
2018 Baron RM, Kwon MY, Castano AP, Ghanta S, Riascos-Bernal DF, Lopez-Guzman S, Macias AA, Ith B, Schissel SL, Lederer JA, Reeves R, Yet SF, Layne MD, Liu X, Perrella MA. Frontline Science: Targeted expression of a dominant-negative high mobility group A1 transgene improves outcome in sepsis. Journal of Leukocyte Biology. PMID 29975792 DOI: 10.1002/Jlb.4Hi0817-333Rr  0.407
2018 Jager M, Lee MJ, Li C, Farmer SR, Fried SK, Layne MD. Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue. Plos One. 13: e0197777. PMID 29799877 DOI: 10.1371/Journal.Pone.0197777  0.656
2018 Blackburn PR, Xu Z, Tumelty KE, Zhao RW, Monis WJ, Harris KG, Gass JM, Cousin MA, Boczek NJ, Mitkov MV, Cappel MA, Francomano CA, Parisi JE, Klee EW, Faqeih E, ... ... Layne MD, et al. Bi-allelic Alterations in AEBP1 Lead to Defective Collagen Assembly and Connective Tissue Structure Resulting in a Variant of Ehlers-Danlos Syndrome. American Journal of Human Genetics. PMID 29606302 DOI: 10.1016/J.Ajhg.2018.02.018  0.339
2015 Shiwen X, Stratton R, Nikitorowicz-Buniak J, Ahmed-Abdi B, Ponticos M, Denton C, Abraham D, Takahashi A, Suki B, Layne MD, Lafyatis R, Smith BD. A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. Plos One. 10: e0126015. PMID 25955164 DOI: 10.1371/Journal.Pone.0126015  0.427
2015 McDonald ME, Li C, Bian H, Smith BD, Layne MD, Farmer SR. Myocardin-related transcription factor A regulates conversion of progenitors to beige adipocytes. Cell. 160: 105-18. PMID 25579684 DOI: 10.1016/J.Cell.2014.12.005  0.711
2015 Xu YX, Ashline D, Liu L, Tassa C, Shaw SY, Ravid K, Layne MD, Reinhold V, Robbins PW. The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis. Journal of Lipid Research. 56: 266-76. PMID 25528754 DOI: 10.1194/Jlr.M053017  0.373
2014 Chen CH, Ho HH, Wu ML, Layne MD, Yet SF. Modulation of cysteine-rich protein 2 expression in vascular injury and atherosclerosis. Molecular Biology Reports. 41: 7033-41. PMID 25034893 DOI: 10.1007/S11033-014-3591-X  0.439
2014 Wu ML, Chen CH, Lin YT, Jheng YJ, Ho YC, Yang LT, Chen L, Layne MD, Yet SF. Divergent signaling pathways cooperatively regulate TGFβ induction of cysteine-rich protein 2 in vascular smooth muscle cells. Cell Communication and Signaling : Ccs. 12: 22. PMID 24674138 DOI: 10.1186/1478-811X-12-22  0.402
2014 Tumelty KE, Smith BD, Nugent MA, Layne MD. Aortic carboxypeptidase-like protein (ACLP) enhances lung myofibroblast differentiation through transforming growth factor β receptor-dependent and -independent pathways. The Journal of Biological Chemistry. 289: 2526-36. PMID 24344132 DOI: 10.1074/Jbc.M113.502617  0.439
2013 Chen CH, Ho YC, Ho HH, Chang IC, Kirsch KH, Chuang YJ, Layne MD, Yet SF. Cysteine-rich protein 2 alters p130Cas localization and inhibits vascular smooth muscle cell migration. Cardiovascular Research. 100: 461-71. PMID 23975851 DOI: 10.1093/Cvr/Cvt207  0.378
2012 Wang D, Prakash J, Nguyen P, Davis-Dusenbery BN, Hill NS, Layne MD, Hata A, Lagna G. Bone morphogenetic protein signaling in vascular disease: anti-inflammatory action through myocardin-related transcription factor A. The Journal of Biological Chemistry. 287: 28067-77. PMID 22718766 DOI: 10.1074/Jbc.M112.379487  0.382
2012 Zhou X, Baron RM, Hardin M, Cho MH, Zielinski J, Hawrylkiewicz I, Sliwinski P, Hersh CP, Mancini JD, Lu K, Thibault D, Donahue AL, Klanderman BJ, Rosner B, Raby BA, ... ... Layne MD, et al. Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP. Human Molecular Genetics. 21: 1325-35. PMID 22140090 DOI: 10.1093/Hmg/Ddr569  0.321
2011 Luchsinger LL, Patenaude CA, Smith BD, Layne MD. Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts. The Journal of Biological Chemistry. 286: 44116-25. PMID 22049076 DOI: 10.1074/Jbc.M111.276931  0.41
2011 Davis-Dusenbery BN, Chan MC, Reno KE, Weisman AS, Layne MD, Lagna G, Hata A. down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4. The Journal of Biological Chemistry. 286: 28097-110. PMID 21673106 DOI: 10.1074/Jbc.M111.236950  0.364
2010 Baron RM, Lopez-Guzman S, Riascos DF, Macias AA, Layne MD, Cheng G, Harris C, Chung SW, Reeves R, von Andrian UH, Perrella MA. Distamycin A inhibits HMGA1-binding to the P-selectin promoter and attenuates lung and liver inflammation during murine endotoxemia. Plos One. 5: e10656. PMID 20498830 DOI: 10.1371/Journal.Pone.0010656  0.343
2010 Danzer E, Layne MD, Auber F, Shegu S, Kreiger P, Radu A, Volpe M, Adzick NS, Flake AW. Gastroschisis in mice lacking aortic carboxypeptidase-like protein is associated with a defect in neuromuscular development of the eviscerated intestine. Pediatric Research. 68: 23-8. PMID 20386491 DOI: 10.1203/Pdr.0B013E3181E17C75  0.339
2010 Chen CH, Wu ML, Lee YC, Layne MD, Yet SF. Intronic CArG box regulates cysteine-rich protein 2 expression in the adult but not in developing vasculature. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 835-42. PMID 20075421 DOI: 10.1161/Atvbaha.109.197251  0.378
2009 Schissel SL, Dunsmore SE, Liu X, Shine RW, Perrella MA, Layne MD. Aortic carboxypeptidase-like protein is expressed in fibrotic human lung and its absence protects against bleomycin-induced lung fibrosis. The American Journal of Pathology. 174: 818-28. PMID 19179605 DOI: 10.2353/Ajpath.2009.080856  0.369
2009 Liu X, Ramjiganesh T, Chen YH, Chung SW, Hall SR, Schissel SL, Padera RF, Liao R, Ackerman KG, Kajstura J, Leri A, Anversa P, Yet SF, Layne MD, Perrella MA. Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice. Circulation. 119: 261-8. PMID 19118250 DOI: 10.1161/Circulationaha.108.799536  0.448
2009 Grant MA, Baron RM, Macias AA, Layne MD, Perrella MA, Rigby AC. Netropsin improves survival from endotoxaemia by disrupting HMGA1 binding to the NOS2 promoter. The Biochemical Journal. 418: 103-12. PMID 18937643 DOI: 10.1042/Bj20081427  0.343
2008 Lin DW, Chang IC, Tseng A, Wu ML, Chen CH, Patenaude CA, Layne MD, Yet SF. Transforming growth factor beta up-regulates cysteine-rich protein 2 in vascular smooth muscle cells via activating transcription factor 2. The Journal of Biological Chemistry. 283: 15003-14. PMID 18387947 DOI: 10.1074/Jbc.M801621200  0.478
2008 Takamiya R, Baron RM, Yet SF, Layne MD, Perrella MA. High mobility group A1 protein mediates human nitric oxide synthase 2 gene expression. Febs Letters. 582: 810-4. PMID 18279675 DOI: 10.1016/J.Febslet.2008.02.008  0.372
2006 Chung SW, Chen YH, Yet SF, Layne MD, Perrella MA. Endotoxin-induced down-regulation of Elk-3 facilitates heme oxygenase-1 induction in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 176: 2414-20. PMID 16456000 DOI: 10.4049/Jimmunol.176.4.2414  0.4
2005 Wei J, Gorman TE, Liu X, Ith B, Tseng A, Chen Z, Simon DI, Layne MD, Yet SF. Increased neointima formation in cysteine-rich protein 2-deficient mice in response to vascular injury. Circulation Research. 97: 1323-31. PMID 16269651 DOI: 10.1161/01.Res.0000194331.76925.5C  0.421
2005 Gagnon A, Landry A, Proulx J, Layne MD, Sorisky A. Aortic carboxypeptidase-like protein is regulated by transforming growth factor beta in 3T3-L1 preadipocytes. Experimental Cell Research. 308: 265-72. PMID 15927179 DOI: 10.1016/J.Yexcr.2005.04.031  0.324
2005 Ith B, Wei J, Yet SF, Perrella MA, Layne MD. Aortic carboxypeptidase-like protein is expressed in collagen-rich tissues during mouse embryonic development. Gene Expression Patterns : Gep. 5: 533-7. PMID 15749083 DOI: 10.1016/J.Modgep.2004.11.002  0.423
2004 Baron RM, Carvajal IM, Liu X, Okabe RO, Fredenburgh LE, Macias AA, Chen YH, Ejima K, Layne MD, Perrella MA. Reduction of nitric oxide synthase 2 expression by distamycin A improves survival from endotoxemia. Journal of Immunology (Baltimore, Md. : 1950). 173: 4147-53. PMID 15356165 DOI: 10.4049/Jimmunol.173.6.4147  0.382
2003 Yet SF, Layne MD, Liu X, Chen YH, Ith B, Sibinga NE, Perrella MA. Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1759-61. PMID 12958201 DOI: 10.1096/Fj.03-0187Fje  0.358
2003 Chen YH, Layne MD, Chung SW, Ejima K, Baron RM, Yet SF, Perrella MA. Elk-3 is a transcriptional repressor of nitric-oxide synthase 2. The Journal of Biological Chemistry. 278: 39572-7. PMID 12896968 DOI: 10.1074/Jbc.M308179200  0.391
2003 Chang YF, Wei J, Liu X, Chen YH, Layne MD, Yet SF. Identification of a CArG-independent region of the cysteine-rich protein 2 promoter that directs expression in the developing vasculature. American Journal of Physiology. Heart and Circulatory Physiology. 285: H1675-83. PMID 12791591 DOI: 10.1152/Ajpheart.00165.2003  0.426
2003 Ejima K, Layne MD, Carvajal IM, Kritek PA, Baron RM, Chen YH, Vom Saal J, Levy BD, Yet SF, Perrella MA. Cyclooxygenase-2-deficient mice are resistant to endotoxin-induced inflammation and death. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1325-7. PMID 12738799 DOI: 10.1096/Fj.02-1078Fje  0.348
2002 Ejima K, Layne MD, Carvajal IM, Nanri H, Ith B, Yet SF, Perrella MA. Modulation of the thioredoxin system during inflammatory responses and its effect on heme oxygenase-1 expression. Antioxidants & Redox Signaling. 4: 569-75. PMID 12230868 DOI: 10.1089/15230860260220067  0.361
2002 Watanabe M, Layne MD, Hsieh CM, Maemura K, Gray S, Lee ME, Jain MK. Regulation of smooth muscle cell differentiation by AT-rich interaction domain transcription factors Mrf2alpha and Mrf2beta. Circulation Research. 91: 382-9. PMID 12215486 DOI: 10.1161/01.Res.0000033593.05545.7B  0.39
2002 Gagnon A, Abaiian KJ, Crapper T, Layne MD, Sorisky A. Down-regulation of aortic carboxypeptidase-like protein during the early phase of 3T3-L1 adipogenesis. Endocrinology. 143: 2478-85. PMID 12072377 DOI: 10.1210/Endo.143.7.8875  0.441
2002 Storm van's Gravesande K, Layne MD, Ye Q, Le L, Baron RM, Perrella MA, Santambrogio L, Silverman ES, Riese RJ. IFN regulatory factor-1 regulates IFN-gamma-dependent cathepsin S expression. Journal of Immunology (Baltimore, Md. : 1950). 168: 4488-94. PMID 11970993 DOI: 10.4049/Jimmunol.168.9.4488  0.347
2002 Layne MD, Yet SF, Maemura K, Hsieh CM, Liu X, Ith B, Lee ME, Perrella MA. Characterization of the mouse aortic carboxypeptidase-like protein promoter reveals activity in differentiated and dedifferentiated vascular smooth muscle cells. Circulation Research. 90: 728-36. PMID 11934842 DOI: 10.1161/01.Res.0000013289.97650.C8  0.461
2001 Maemura K, Layne MD, Watanabe M, Perrell MA, Nagai R, Lee ME. Molecular mechanisms of morning onset of myocardial infarction. Annals of the New York Academy of Sciences. 947: 398-402. PMID 11795300 DOI: 10.1111/J.1749-6632.2001.Tb03972.X  0.413
2001 Chen YH, Layne MD, Watanabe M, Yet SF, Perrella MA. Upstream stimulatory factors regulate aortic preferentially expressed gene-1 expression in vascular smooth muscle cells. The Journal of Biological Chemistry. 276: 47658-63. PMID 11606591 DOI: 10.1074/Jbc.M108678200  0.454
2001 Layne MD, Patel A, Chen YH, Rebel VI, Carvajal IM, Pellacani A, Ith B, Zhao D, Schreiber BM, Yet SF, Lee ME, Storch J, Perrella MA. Role of macrophage-expressed adipocyte fatty acid binding protein in the development of accelerated atherosclerosis in hypercholesterolemic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2733-5. PMID 11606480 DOI: 10.1096/Fj.01-0374Fje  0.366
2001 Perrella MA, Pellacani A, Layne MD, Patel A, Zhao D, Schreiber BM, Storch J, Feinberg MW, Hsieh CM, Haber E, Lee ME. Absence of adipocyte fatty acid binding protein prevents the development of accelerated atherosclerosis in hypercholesterolemic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1774-6. PMID 11481226 DOI: 10.1096/Fj.01-0017Fje  0.361
2001 Yet SF, Tian R, Layne MD, Wang ZY, Maemura K, Solovyeva M, Ith B, Melo LG, Zhang L, Ingwall JS, Dzau VJ, Lee ME, Perrella MA. Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice. Circulation Research. 89: 168-73. PMID 11463724 DOI: 10.1161/Hh1401.093314  0.308
2001 Layne MD, Yet SF, Maemura K, Hsieh CM, Bernfield M, Perrella MA, Lee ME. Impaired abdominal wall development and deficient wound healing in mice lacking aortic carboxypeptidase-like protein. Molecular and Cellular Biology. 21: 5256-61. PMID 11438679 DOI: 10.1128/Mcb.21.15.5256-5261.2001  0.403
2001 Sun J, Kamei CN, Layne MD, Jain MK, Liao JK, Lee ME, Chin MT. Regulation of myogenic terminal differentiation by the hairy-related transcription factor CHF2. The Journal of Biological Chemistry. 276: 18591-6. PMID 11279181 DOI: 10.1074/Jbc.M101163200  0.437
2000 Maemura K, de la Monte SM, Chin MT, Layne MD, Hsieh CM, Yet SF, Perrella MA, Lee ME. CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression. The Journal of Biological Chemistry. 275: 36847-51. PMID 11018023 DOI: 10.1074/Jbc.C000629200  0.393
2000 Hsieh CM, Fukumoto S, Layne MD, Maemura K, Charles H, Patel A, Perrella MA, Lee ME. Striated muscle preferentially expressed genes alpha and beta are two serine/threonine protein kinases derived from the same gene as the aortic preferentially expressed gene-1. The Journal of Biological Chemistry. 275: 36966-73. PMID 10973969 DOI: 10.1074/Jbc.M006028200  0.397
2000 Wiesel P, Foster LC, Pellacani A, Layne MD, Hsieh CM, Huggins GS, Strauss P, Yet SF, Perrella MA. Thioredoxin facilitates the induction of heme oxygenase-1 in response to inflammatory mediators. The Journal of Biological Chemistry. 275: 24840-6. PMID 10823822 DOI: 10.1074/Jbc.M000835200  0.349
2000 Chin MT, Maemura K, Fukumoto S, Jain MK, Layne MD, Watanabe M, Hsieh CM, Lee ME. Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular system. The Journal of Biological Chemistry. 275: 6381-7. PMID 10692439 DOI: 10.1074/Jbc.275.9.6381  0.437
1999 Maemura K, Hsieh CM, Jain MK, Fukumoto S, Layne MD, Liu Y, Kourembanas S, Yet SF, Perrella MA, Lee ME. Generation of a dominant-negative mutant of endothelial PAS domain protein 1 by deletion of a potent C-terminal transactivation domain. The Journal of Biological Chemistry. 274: 31565-70. PMID 10531360 DOI: 10.1074/Jbc.274.44.31565  0.383
1999 Layne MD, Farmer SR. Tumor necrosis factor-alpha and basic fibroblast growth factor differentially inhibit the insulin-like growth factor-I induced expression of myogenin in C2C12 myoblasts. Experimental Cell Research. 249: 177-87. PMID 10328964 DOI: 10.1006/Excr.1999.4465  0.611
1999 Hsieh CM, Yet SF, Layne MD, Watanabe M, Hong AM, Perrella MA, Lee ME. Genomic cloning and promoter analysis of aortic preferentially expressed gene-1. Identification of a vascular smooth muscle-specific promoter mediated by an E box motif. The Journal of Biological Chemistry. 274: 14344-51. PMID 10318857 DOI: 10.1074/Jbc.274.20.14344  0.417
1999 Yet SF, Perrella MA, Layne MD, Hsieh CM, Maemura K, Kobzik L, Wiesel P, Christou H, Kourembanas S, Lee ME. Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice. The Journal of Clinical Investigation. 103: R23-9. PMID 10207174 DOI: 10.1172/Jci6163  0.332
1998 Jain MK, Kashiki S, Hsieh CM, Layne MD, Yet SF, Sibinga NE, Chin MT, Feinberg MW, Woo I, Maas RL, Haber E, Lee ME. Embryonic expression suggests an important role for CRP2/SmLIM in the developing cardiovascular system. Circulation Research. 83: 980-5. PMID 9815145 DOI: 10.1161/01.Res.83.10.980  0.44
1998 Layne MD, Endege WO, Jain MK, Yet SF, Hsieh CM, Chin MT, Perrella MA, Blanar MA, Haber E, Lee ME. Aortic carboxypeptidase-like protein, a novel protein with discoidin and carboxypeptidase-like domains, is up-regulated during vascular smooth muscle cell differentiation. The Journal of Biological Chemistry. 273: 15654-60. PMID 9624159 DOI: 10.1074/Jbc.273.25.15654  0.428
1998 Yet SF, Folta SC, Jain MK, Hsieh CM, Maemura K, Layne MD, Zhang D, Marria PB, Yoshizumi M, Chin MT, Perrella MA, Lee ME. Molecular cloning, characterization, and promoter analysis of the mouse Crp2/SmLim gene. Preferential expression of its promoter in the vascular smooth muscle cells of transgenic mice. The Journal of Biological Chemistry. 273: 10530-7. PMID 9553112 DOI: 10.1074/Jbc.273.17.10530  0.422
1998 Jain MK, Layne MD, Watanabe M, Chin MT, Feinberg MW, Sibinga NE, Hsieh CM, Yet SF, Stemple DL, Lee ME. In vitro system for differentiating pluripotent neural crest cells into smooth muscle cells. The Journal of Biological Chemistry. 273: 5993-6. PMID 9497310 DOI: 10.1074/Jbc.273.11.5993  0.406
1998 Yet SF, McA'Nulty MM, Folta SC, Yen HW, Yoshizumi M, Hsieh CM, Layne MD, Chin MT, Wang H, Perrella MA, Jain MK, Lee ME. Human EZF, a Krüppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domains. The Journal of Biological Chemistry. 273: 1026-31. PMID 9422764 DOI: 10.1074/Jbc.273.2.1026  0.377
1994 Schreiber BM, Layne MD, Modest EJ. Superoxide production by macrophages stimulated in vivo with synthetic ether lipids Lipids. 29: 237-242. PMID 8177017 DOI: 10.1007/Bf02536327  0.334
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