| Year |
Citation |
Score |
| 2023 |
Hemanth P, Nistala P, Nguyen VT, Eltit JM, Glennon RA, Dukat M. Binding and functional structure-activity similarities of 4-substituted 2,5-dimethoxyphenyl isopropylamine analogues at 5-HT and 5-HT serotonin receptors. Frontiers in Pharmacology. 14: 1101290. PMID 36762110 DOI: 10.3389/fphar.2023.1101290 |
0.454 |
|
| 2020 |
Davies RA, Baird TR, Nguyen VT, Ruiz B, Sakloth F, Eltit JM, Negus SS, Glennon RA. An investigation of the optical isomers of methcathinone (MCAT), and two achiral analogs, at monoamine transporters and in intracranial self- stimulation studies in rats. Acs Chemical Neuroscience. PMID 32356961 DOI: 10.1021/Acschemneuro.9B00617 |
0.753 |
|
| 2019 |
Yadav-Samudrala BJ, Eltit JM, Glennon RA. Synthetic Cathinone Analogs Structurally Related to the Central Stimulant Methylphenidate as Dopamine Reuptake Inhibitors. Acs Chemical Neuroscience. PMID 31369229 DOI: 10.1021/Acschemneuro.9B00284 |
0.358 |
|
| 2019 |
Shah UH, Gaitonde SA, Moreno JL, Glennon RA, Dukat M, González-Maeso J. A revised pharmacophore model for 5-HT2A receptor antagonists derived from the atypical antipsychotic agent risperidone. Acs Chemical Neuroscience. PMID 30609893 DOI: 10.1021/Acschemneuro.8B00637 |
0.521 |
|
| 2018 |
Walther D, Shalabi AR, Baumann MH, Glennon RA. Systematic structure-activity studies on selected 2-, 3-, and 4-monosubstituted synthetic methcathinone analogs as monoamine transporter releasing agents. Acs Chemical Neuroscience. PMID 30354055 DOI: 10.1021/Acschemneuro.8B00524 |
0.367 |
|
| 2018 |
Dukat M, Jain AD, German N, Ferrara-Pontoriero R, Huang Y, Ma Y, Schulte MK, Glennon RA. des-Formylflustrabromine (dFBr): A Structure-Activity Study on its Ability to Potentiate the Action of Acetylcholine at α4β2 Nicotinic Acetylcholine Receptors. Acs Chemical Neuroscience. PMID 30028943 DOI: 10.1021/Acschemneuro.8B00156 |
0.748 |
|
| 2018 |
Battisti UM, Sitta R, Harris A, Sakloth F, Walther D, Ruchala I, Negus S, Baumann MH, Glennon RA, Eltit JM. Effects of N-alkyl-4-methylamphetamine optical isomers on plasma membrane monoamine transporters and abuse-related behavior. Acs Chemical Neuroscience. PMID 29697951 DOI: 10.1021/Acschemneuro.8B00138 |
0.769 |
|
| 2017 |
Solis E, Partilla JS, Sakloth F, Ruchala I, Schwienteck KL, De Felice LJ, Eltit JM, Glennon RA, Negus SS, Baumann MH. N-Alkylated Analogs of 4-Methylamphetamine (4-MA) Differentially Affect Monoamine Transporters and Abuse Liability. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28530234 DOI: 10.1038/Npp.2017.98 |
0.771 |
|
| 2017 |
Glennon RA. 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse. Journal of Medicinal Chemistry. PMID 28244748 DOI: 10.1021/Acs.Jmedchem.7B00085 |
0.401 |
|
| 2017 |
Shalabi AR, Walther D, Baumann MH, Glennon RA. Deconstructed analogs of bupropion reveal structural requirements for transporter inhibition versus substrate-induced neurotransmitter release. Acs Chemical Neuroscience. PMID 28220701 DOI: 10.1021/Acschemneuro.7B00055 |
0.342 |
|
| 2017 |
Walters HM, Dillon-Carter O, Partilla JS, Sakloth F, Glennon RA, Schindler CW, Baumann MH. 3,4-Methylenedioxy-N-ethylcathinone and its analogs differentially affect dopamine and 5-HT systems in rat brain Drug and Alcohol Dependence. 171: e211. DOI: 10.1016/J.Drugalcdep.2016.08.577 |
0.788 |
|
| 2016 |
Glennon RA, Dukat M. Structure-Activity Relationships of Synthetic Cathinones. Current Topics in Behavioral Neurosciences. PMID 27830576 DOI: 10.1007/7854_2016_41 |
0.367 |
|
| 2016 |
Younkin J, Gaitonde SA, Ellaithy A, Vekariya RH, Baki L, Moreno JL, Shah S, Drossopoulos P, Hideshima KS, Eltit JM, González-Maeso J, Logothetis DE, Dukat M, Glennon RA. Reformulating a Pharmacophore for 5-HT2A Serotonin Receptor Antagonists. Acs Chemical Neuroscience. PMID 27385190 DOI: 10.1021/Acschemneuro.6B00162 |
0.519 |
|
| 2016 |
Glennon RA, Young R. Neurobiology of 3,4-methylenedioxypyrovalerone (MDPV) and α-pyrrolidinovalerophenone (α-PVP). Brain Research Bulletin. PMID 27142261 DOI: 10.1016/J.Brainresbull.2016.04.011 |
0.345 |
|
| 2016 |
Suyama JA, Sakloth F, Kolanos R, Glennon RA, Lazenka MF, Negus SS, Banks ML. Abuse-Related Neurochemical Effects of Para-Substituted Methcathinone Analogs in Rats: Microdialysis Studies of Nucleus Accumbens Dopamine and Serotonin. The Journal of Pharmacology and Experimental Therapeutics. 356: 182-90. PMID 26645638 DOI: 10.1124/Jpet.115.229559 |
0.791 |
|
| 2015 |
Hutsell BA, Baumann MH, Partilla JS, Banks ML, Vekariya R, Glennon RA, Negus SS. Abuse-related neurochemical and behavioral effects of cathinone and 4-methylcathinone stereoisomers in rats. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26738428 DOI: 10.1016/J.Euroneuro.2015.12.010 |
0.341 |
|
| 2015 |
May JA, Sharif NA, McLaughlin MA, Chen HH, Severns BS, Kelly CR, Holt WF, Young R, Glennon RA, Hellberg MR, Dean TR. Ocular Hypotensive Response in Nonhuman Primates of (8R)-1-[(2S)-2-Aminopropyl]-8,9-dihydro-7H-pyrano[2,3-g]indazol-8-ol a Selective 5-HT2 Receptor Agonist. Journal of Medicinal Chemistry. PMID 26551970 DOI: 10.1021/Acs.Jmedchem.5B00857 |
0.455 |
|
| 2015 |
Del Bello F, Sakloth F, Partilla JS, Baumann MH, Glennon RA. Ethylenedioxy homologs of N-methyl-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) and its corresponding cathinone analog methylenedioxymethcathinone: Interactions with transporters for serotonin, dopamine, and norepinephrine. Bioorganic & Medicinal Chemistry. 23: 5574-9. PMID 26233799 DOI: 10.1016/J.Bmc.2015.07.035 |
0.771 |
|
| 2015 |
Kolanos R, Sakloth F, Jain AD, Partilla JS, Baumann MH, Glennon RA. Structural Modification of the Designer Stimulant α-Pyrrolidinovalerophenone (α-PVP) Influences Potency at Dopamine Transporters. Acs Chemical Neuroscience. PMID 26217965 DOI: 10.1021/Acschemneuro.5B00160 |
0.779 |
|
| 2015 |
Hamouda AK, Wang ZJ, Stewart DS, Jain AD, Glennon RA, Cohen JB. Desformylflustrabromine (dFBr) and [3H]dFBr-Labeled Binding Sites in a Nicotinic Acetylcholine Receptor. Molecular Pharmacology. 88: 1-11. PMID 25870334 DOI: 10.1124/Mol.115.098913 |
0.52 |
|
| 2015 |
Kolanos R, Partilla JS, Baumann MH, Hutsell BA, Banks ML, Negus SS, Glennon RA. Stereoselective Actions of Methylenedioxypyrovalerone (MDPV) To Inhibit Dopamine and Norepinephrine Transporters and Facilitate Intracranial Self-Stimulation in Rats. Acs Chemical Neuroscience. 6: 771-7. PMID 25688761 DOI: 10.1021/Acschemneuro.5B00006 |
0.356 |
|
| 2015 |
Tang QY, Kolanos R, De Felice LJ, Glennon RA. Structural analysis of dopamine- and amphetamine-induced depolarization currents in the human dopamine transporter. Acs Chemical Neuroscience. 6: 551-8. PMID 25594379 DOI: 10.1021/Cn500282F |
0.302 |
|
| 2015 |
Sakloth F, Kolanos R, Mosier PD, Bonano JS, Banks ML, Partilla JS, Baumann MH, Negus SS, Glennon RA. Steric parameters, molecular modeling and hydropathic interaction analysis of the pharmacology of para-substituted methcathinone analogues. British Journal of Pharmacology. 172: 2210-8. PMID 25522019 DOI: 10.1111/Bph.13043 |
0.784 |
|
| 2015 |
Bonano JS, Banks ML, Kolanos R, Sakloth F, Barnier ML, Glennon RA, Cozzi NV, Partilla JS, Baumann MH, Negus SS. Quantitative structure-activity relationship analysis of the pharmacology of para-substituted methcathinone analogues. British Journal of Pharmacology. 172: 2433-44. PMID 25438806 DOI: 10.1111/Bph.13030 |
0.759 |
|
| 2015 |
Solis E, Zdravkovic I, Kolanos R, Sakloth F, Noskov SY, Glennon RA, De Felice LJ. Characterization of a Secondary Site of Drug Action on the Human Dopamine Transporter Biophysical Journal. 108: 462a. DOI: 10.1016/J.Bpj.2014.11.2521 |
0.755 |
|
| 2015 |
Del Bello F, Sakloth F, Partilla JS, Baumann MH, Glennon RA. Ethylenedioxy homologs of N-methyl-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) and its corresponding cathinone analog methylenedioxymethcathinone: Interactions with transporters for serotonin, dopamine, and norepinephrine Bioorganic and Medicinal Chemistry. DOI: 10.1016/j.bmc.2015.07.035 |
0.754 |
|
| 2014 |
Bonano JS, Runyon SP, Hassler C, Glennon RA, Stevens Negus S. Effects of the neuropeptide S receptor antagonist RTI-118 on abuse-related facilitation of intracranial self-stimulation produced by cocaine and methylenedioxypyrovalerone (MDPV) in rats. European Journal of Pharmacology. 743: 98-105. PMID 25220242 DOI: 10.1016/J.Ejphar.2014.09.006 |
0.351 |
|
| 2014 |
Rao BK, Samanta D, Joshi S, Basu K, Baldwin SD, Jha A, Dukat M, Glennon RA, Jena P. Receptor-ligand interaction at 5-HT3 serotonin receptors: a cluster approach. The Journal of Physical Chemistry. A. 118: 8471-6. PMID 24878072 DOI: 10.1021/Jp5017906 |
0.475 |
|
| 2014 |
Ruchala I, Cabra V, Solis E, Glennon RA, De Felice LJ, Eltit JM. Electrical coupling between the human serotonin transporter and voltage-gated Ca(2+) channels. Cell Calcium. 56: 25-33. PMID 24854234 DOI: 10.1016/J.Ceca.2014.04.003 |
0.316 |
|
| 2014 |
Glennon RA. Bath salts, mephedrone, and methylenedioxypyrovalerone as emerging illicit drugs that will need targeted therapeutic intervention. Advances in Pharmacology (San Diego, Calif.). 69: 581-620. PMID 24484988 DOI: 10.1016/B978-0-12-420118-7.00015-9 |
0.358 |
|
| 2013 |
Kolanos R, Solis E, Sakloth F, De Felice LJ, Glennon RA. "Deconstruction" of the abused synthetic cathinone methylenedioxypyrovalerone (MDPV) and an examination of effects at the human dopamine transporter. Acs Chemical Neuroscience. 4: 1524-9. PMID 24116392 DOI: 10.1021/Cn4001236 |
0.762 |
|
| 2013 |
Cameron K, Kolanos R, Verkariya R, De Felice L, Glennon RA. Mephedrone and methylenedioxypyrovalerone (MDPV), major constituents of "bath salts," produce opposite effects at the human dopamine transporter Psychopharmacology. 227: 493-499. PMID 23371489 DOI: 10.1007/S00213-013-2967-2 |
0.33 |
|
| 2013 |
Cameron KN, Kolanos R, Solis E, Glennon RA, De Felice LJ. Bath salts components mephedrone and methylenedioxypyrovalerone (MDPV) act synergistically at the human dopamine transporter. British Journal of Pharmacology. 168: 1750-7. PMID 23170765 DOI: 10.1111/Bph.12061 |
0.338 |
|
| 2013 |
Cabra V, Leal-Pinto E, Samso M, Glennon RA, De Felice LJ, Eltit JM. S(+)MDMA and 5-HT Evoke Dissimilar Ionic Currents in Human Serotonin Transporter-Expressing Cells Biophysical Journal. 104: 110a. DOI: 10.1016/J.Bpj.2012.11.637 |
0.423 |
|
| 2012 |
Cameron KN, Kolanos R, Solis E, Vekariya RH, Glennon RA, De Felice LJ. Bath Salts: A Synthetic Cathinone Whose Two Major Components Act Similar to Methamphetamine and Cocaine on the Human Dopamine Transporter Biophysical Journal. 102: 215a. DOI: 10.1016/J.Bpj.2011.11.1178 |
0.352 |
|
| 2012 |
Rahman AA, Daoud MK, Dukat M, Herrick-Davis K, Purohit A, Teitler M, do Amaral AT, Malvezzi A, Glennon RA. Corrigendum to “Conformationally-restricted analogues and partition coefficients of the 5-HT3 serotonin receptor ligands meta-Chlorophenylbiguanide (mCPBG) and meta-Chlorophenylguanidine (mCPG)” [Bioorg. Med. Chem. Lett. 15 (2005) 3434–3438] Bioorganic & Medicinal Chemistry Letters. 22: 6526. DOI: 10.1016/J.Bmcl.2012.08.076 |
0.464 |
|
| 2011 |
German N, Kim JS, Jain A, Dukat M, Pandya A, Ma Y, Weltzin M, Schulte MK, Glennon RA. Deconstruction of the α4β2 nicotinic acetylcholine receptor positive allosteric modulator desformylflustrabromine Journal of Medicinal Chemistry. 54: 7259-7267. PMID 21905680 DOI: 10.1021/Jm200834X |
0.753 |
|
| 2011 |
Zhang X, Andren PE, Glennon RA, Svenningsson P. Distribution, level, pharmacology, regulation, and signaling of 5-HT6 receptors in rats and marmosets with special reference to an experimental model of parkinsonism. The Journal of Comparative Neurology. 519: 1816-27. PMID 21452237 DOI: 10.1002/Cne.22605 |
0.534 |
|
| 2011 |
Klein MT, Dukat M, Glennon RA, Teitler M. Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships. The Journal of Pharmacology and Experimental Therapeutics. 337: 860-7. PMID 21422162 DOI: 10.1124/Jpet.111.179606 |
0.554 |
|
| 2010 |
Dukat M, Wesolowska A, Alley G, Young S, Abdrakhmanova GR, Navarro HA, Young R, Glennon RA. MD-354 selectively antagonizes the antinociceptive effects of (-)nicotine in the mouse tail-flick assay Psychopharmacology. 210: 547-557. PMID 20431995 DOI: 10.1007/S00213-010-1857-0 |
0.407 |
|
| 2010 |
Glennon RA, Siripurapu U, Roth BL, Kolanos R, Bondarev ML, Sikazwe D, Lee M, Dukat M. The medicinal chemistry of 5-HT6 receptor ligands with a focus on arylsulfonyltryptamine analogs. Current Topics in Medicinal Chemistry. 10: 579-95. PMID 20166945 DOI: 10.2174/156802610791111542 |
0.836 |
|
| 2010 |
HONG S, DUKAT M, TEITLER M, HERRICK-DAVIS K, MCCALLUM K, KAMBOJ R, GLENNON RA. ChemInform Abstract: Binding of 5-Arylalkyloxytryptamines at Human 5-HT1Dβ Serotonin Receptors. Cheminform. 27: no-no. DOI: 10.1002/CHIN.199621126 |
0.38 |
|
| 2010 |
GLENNON RA, CHAURASIA C, TITELER M. ChemInform Abstract: Binding of Indolylalkylamines at 5-HT2 Serotonin Receptors: Examination of a Hydrophobic Binding Region. Cheminform. 22: no-no. DOI: 10.1002/CHIN.199110151 |
0.441 |
|
| 2009 |
Abate C, Mosier PD, Berardi F, Glennon RA. A structure-affinity and comparative molecular field analysis of sigma-2 (σ2) receptor ligands Central Nervous System Agents in Medicinal Chemistry. 9: 246-257. PMID 20021358 DOI: 10.2174/1871524910909030246 |
0.421 |
|
| 2009 |
Keiser MJ, Setola V, Irwin JJ, Laggner C, Abbas AI, Hufeisen SJ, Jensen NH, Kuijer MB, Matos RC, Tran TB, Whaley R, Glennon RA, Hert J, Thomas KL, Edwards DD, et al. Predicting new molecular targets for known drugs. Nature. 462: 175-81. PMID 19881490 DOI: 10.1038/Nature08506 |
0.369 |
|
| 2009 |
Young R, Glennon RA. S(-)Propranolol as a discriminative stimulus and its comparison to the stimulus effects of cocaine in rats Psychopharmacology. 203: 369-382. PMID 18795268 DOI: 10.1007/S00213-008-1317-2 |
0.312 |
|
| 2009 |
Khorana N, Young R, Glennon RA. Effect of 8-hydroxy-2-(N,N-di-n-propylamino)tetralin and MDMA on the discriminative stimulus effects of the classical hallucinogen DOM in rats Pharmacology Biochemistry and Behavior. 91: 385-392. PMID 18778728 DOI: 10.1016/J.Pbb.2008.08.013 |
0.768 |
|
| 2009 |
May JA, Sharif NA, Chen HH, Liao JC, Kelly CR, Glennon RA, Young R, Li JX, Rice KC, France CP. Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT2 receptor agonist AL-38022A [(S)-2-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)-1-methylethylamine]. Pharmacology, Biochemistry, and Behavior. 91: 307-14. PMID 18718483 DOI: 10.1016/J.Pbb.2008.07.015 |
0.623 |
|
| 2008 |
Runyon SP, Mosier PD, Roth BL, Glennon RA, Westkaemper RB. Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation. Journal of Medicinal Chemistry. 51: 6808-28. PMID 18847250 DOI: 10.1021/Jm800771X |
0.536 |
|
| 2008 |
Dukat M, Mosier PD, Kolanos R, Roth BL, Glennon RA. Binding of serotonin and N1-benzenesulfonyltryptamine-related analogs at human 5-HT6 serotonin receptors: receptor modeling studies. Journal of Medicinal Chemistry. 51: 603-11. PMID 18201064 DOI: 10.1021/Jm070910S |
0.567 |
|
| 2008 |
Young R, Glennon RA. MDMA (N-methyl-3,4-methylenedioxyamphetamine) and its stereoisomers: Similarities and differences in behavioral effects in an automated activity apparatus in mice Pharmacology Biochemistry and Behavior. 88: 318-331. PMID 17904622 DOI: 10.1016/J.Pbb.2007.09.002 |
0.322 |
|
| 2007 |
Kim JS, Padnya A, Weltzin M, Edmonds BW, Schulte MK, Glennon RA. Synthesis of desformylflustrabromine and its evaluation as an α4β2 and α7 nACh receptor modulator Bioorganic and Medicinal Chemistry Letters. 17: 4855-4860. PMID 17604168 DOI: 10.1016/J.Bmcl.2007.06.047 |
0.35 |
|
| 2007 |
Dukat M, Wesolowska A, Young R, Glennon RA. The 5-HT3 receptor partial agonist MD-354 (meta-chlorophenylguanidine) enhances the discriminative stimulus actions of (+)amphetamine in rats Pharmacology Biochemistry and Behavior. 87: 203-207. PMID 17540440 DOI: 10.1016/J.Pbb.2007.03.008 |
0.39 |
|
| 2007 |
Dukat M, Glennon RA, Young S. MD-354: What is it good for? Cns Drug Reviews. 13: 1-20. PMID 17461887 DOI: 10.1111/J.1527-3458.2007.00002.X |
0.545 |
|
| 2007 |
Glennon RA, Young R, Dukat M, Chang-Fong J, El-Zahabi M. N-Methyl-1-(4-methoxyphenyl)-2-aminopropane (PMMA) and N-Methyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) produce non-identical discriminative stimuli in rats Pharmacology Biochemistry and Behavior. 86: 477-484. PMID 17307247 DOI: 10.1016/J.Pbb.2007.01.007 |
0.392 |
|
| 2007 |
Nyandege A, Kolanos R, Roth BL, Glennon RA. Further studies on the binding of N1-substituted tryptamines at h5-HT6 receptors. Bioorganic & Medicinal Chemistry Letters. 17: 1691-4. PMID 17239595 DOI: 10.1016/J.Bmcl.2006.12.089 |
0.542 |
|
| 2006 |
Young R, Bondareva T, Wesolowska A, Young S, Glennon RA. Effect of the 5-HT6 serotonin antagonist MS-245 on the actions of (-)nicotine Pharmacology Biochemistry and Behavior. 85: 170-177. PMID 16950502 DOI: 10.1016/J.Pbb.2006.07.029 |
0.401 |
|
| 2006 |
Kolanos R, Dukat M, Roth BL, Glennon RA. Interaction of N1-unsubstituted and N1-benzenesulfonyltryptamines at h5-HT6 receptors. Bioorganic & Medicinal Chemistry Letters. 16: 5832-5. PMID 16945532 DOI: 10.1016/J.Bmcl.2006.08.068 |
0.539 |
|
| 2006 |
Sikazwe D, Bondarev ML, Dukat M, Rangisetty JB, Roth BL, Glennon RA. Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors. Journal of Medicinal Chemistry. 49: 5217-25. PMID 16913710 DOI: 10.1021/Jm060469Q |
0.566 |
|
| 2006 |
Ragab HM, Kim JS, Dukat M, Navarro H, Glennon RA. Aryloxyethylamines: Binding at α7 nicotinic acetylcholine receptors Bioorganic and Medicinal Chemistry Letters. 16: 4283-4286. PMID 16765047 DOI: 10.1016/J.Bmcl.2006.05.080 |
0.447 |
|
| 2006 |
Young R, Batkai S, Dukat M, Glennon RA. TDIQ (5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline) exhibits anxiolytic-like activity in a marble-burying assay in mice Pharmacology Biochemistry and Behavior. 84: 62-73. PMID 16750844 DOI: 10.1016/J.Pbb.2006.04.006 |
0.316 |
|
| 2006 |
Young R, Rothman RB, Rangisetty JB, Partilla JS, Dukat M, Glennon RA. TDIQ (5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline) inhibits the consumption of "snacks" in mice Pharmacology Biochemistry and Behavior. 84: 74-83. PMID 16750261 DOI: 10.1016/J.Pbb.2006.04.007 |
0.341 |
|
| 2006 |
Siripurapu U, Kolanos R, Dukat M, Roth BL, Glennon RA. Binding of methoxy-substituted N1-benzenesulfonylindole analogs at human 5-HT6 serotonin receptors. Bioorganic & Medicinal Chemistry Letters. 16: 3793-6. PMID 16709453 DOI: 10.1016/J.Bmcl.2006.04.094 |
0.856 |
|
| 2006 |
Young R, Bondareva T, Wesolowska A, Glennon RA. Modulation of a (+)amphetamine discriminative stimulus in rats by 8-hydroxy-2-(N,N-di-n-propylamino)tetralin (8-OH DPAT) Pharmacology Biochemistry and Behavior. 83: 612-617. PMID 16675002 DOI: 10.1016/J.Pbb.2006.03.025 |
0.407 |
|
| 2006 |
Glennon RA. 3-(4-(Tetrahydropyridin-1-yl) butyl) oxindoles as 5-HT 7 receptor Expert Opinion On Therapeutic Patents. 16: 1171-1174. DOI: 10.1517/13543776.16.8.1171 |
0.521 |
|
| 2005 |
Bondareva T, Weso?owska A, Dukat M, Lee M, Young R, Glennon RA. S(+)- and R(-)N-Methyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) as discriminative stimuli: Effect of cocaine Pharmacology Biochemistry and Behavior. 82: 531-538. PMID 16337676 DOI: 10.1016/J.Pbb.2005.10.008 |
0.333 |
|
| 2005 |
Young R, Khorana N, Bondareva T, Glennon RA. Pizotyline effectively attenuates the stimulus effects of N-Methyl-3,4-methylenedioxyamphetamine (MDMA) Pharmacology Biochemistry and Behavior. 82: 404-410. PMID 16253319 DOI: 10.1016/J.Pbb.2005.09.010 |
0.755 |
|
| 2005 |
Pullagurla M, Siripurapu U, Kolanos R, Bondarev ML, Dukat M, Setola V, Roth BL, Glennon RA. Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors. Bioorganic & Medicinal Chemistry Letters. 15: 5298-302. PMID 16183286 DOI: 10.1016/J.Bmcl.2005.08.059 |
0.839 |
|
| 2005 |
Dukat M, Ramunno A, Banzi R, Damaj MI, Martin B, Glennon RA. 3-(2-Aminoethyl)pyridine analogs as α4β2 nicotinic cholinergic receptor ligands Bioorganic and Medicinal Chemistry Letters. 15: 4308-4312. PMID 16039854 DOI: 10.1016/J.Bmcl.2005.06.053 |
0.367 |
|
| 2005 |
Abate C, Kolanos R, Dukat M, Setola V, Roth BL, Glennon RA. Interaction of chiral MS-245 analogs at h5-HT6 receptors. Bioorganic & Medicinal Chemistry Letters. 15: 3510-3. PMID 15990303 DOI: 10.1016/J.Bmcl.2005.05.092 |
0.507 |
|
| 2005 |
Setola V, Dukat M, Glennon RA, Roth BL. Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor. Molecular Pharmacology. 68: 20-33. PMID 15831837 DOI: 10.1124/Mol.104.009266 |
0.524 |
|
| 2005 |
Kolanos R, Siripurapu U, Pullagurla M, Riaz M, Setola V, Roth BL, Dukat M, Glennon RA. Binding of isotryptamines and indenes at h5-HT6 serotonin receptors. Bioorganic & Medicinal Chemistry Letters. 15: 1987-91. PMID 15808453 DOI: 10.1016/J.Bmcl.2005.02.070 |
0.824 |
|
| 2005 |
Kolanos R, Siripurapu U, Pullagurla M, Riaz M, Setola V, Roth BL, Dukat M, Glennon RA. Binding of isotryptamines and indenes at h5-HT6 serotonin receptors. Bioorganic & Medicinal Chemistry Letters. 15: 1987-91. PMID 15808453 DOI: 10.1016/J.Bmcl.2005.02.070 |
0.824 |
|
| 2005 |
Lee M, Rangisetty JB, Pullagurla MR, Dukat M, Setola V, Roth BL, Glennon RA. 1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands. Bioorganic & Medicinal Chemistry Letters. 15: 1707-11. PMID 15745826 DOI: 10.1016/J.Bmcl.2005.01.031 |
0.842 |
|
| 2005 |
Lee M, Rangisetty JB, Pullagurla MR, Dukat M, Setola V, Roth BL, Glennon RA. 1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands. Bioorganic & Medicinal Chemistry Letters. 15: 1707-11. PMID 15745826 DOI: 10.1016/J.Bmcl.2005.01.031 |
0.842 |
|
| 2005 |
Glennon RA. Binding characteristics of sigma2 receptor ligands Revista Brasileira De Ciencias Farmaceuticas. 41: 1-12. DOI: 10.1590/S1516-93322005000100002 |
0.412 |
|
| 2005 |
Pullagurla M, Dukat M, Roth BL, Setola V, Glennon RA. 5-Azatryptamine analogs as h5-HT6 serotonin receptor ligands Medicinal Chemistry Research. 14: 1-18. DOI: 10.1007/S00044-004-0121-8 |
0.863 |
|
| 2004 |
Glennon RA, Bondarev ML, Khorana N, Young R, May JA, Hellberg MR, McLaughlin MA, Sharif NA. Beta-oxygenated analogues of the 5-HT2A serotonin receptor agonist 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. Journal of Medicinal Chemistry. 47: 6034-41. PMID 15537358 DOI: 10.1021/Jm040082S |
0.777 |
|
| 2004 |
Glennon RA, Bondarev ML, Khorana N, Young R, May JA, Hellberg MR, McLaughlin MA, Sharif NA. Beta-oxygenated analogues of the 5-HT2A serotonin receptor agonist 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. Journal of Medicinal Chemistry. 47: 6034-41. PMID 15537358 DOI: 10.1021/Jm040082S |
0.777 |
|
| 2004 |
Pullagurla MR, Westkaemper RB, Glennon RA. Possible differences in modes of agonist and antagonist binding at human 5-HT6 receptors Bioorganic and Medicinal Chemistry Letters. 14: 4569-4573. PMID 15357994 DOI: 10.1016/J.Bmcl.2004.05.076 |
0.85 |
|
| 2004 |
Pullagurla MR, Westkaemper RB, Glennon RA. Possible differences in modes of agonist and antagonist binding at human 5-HT6 receptors Bioorganic and Medicinal Chemistry Letters. 14: 4569-4573. PMID 15357994 DOI: 10.1016/j.bmcl.2004.05.076 |
0.433 |
|
| 2004 |
Prisinzano T, Dukat M, Law H, Slassi A, MacLean N, DeLannoy I, Glennon RA. 2-(Anilino)imidazolines and 2-(benzyl)imidazoline derivatives as h5-HT 1D serotonin receptor ligands Bioorganic and Medicinal Chemistry Letters. 14: 4697-4699. PMID 15324890 DOI: 10.1016/J.Bmcl.2004.06.085 |
0.698 |
|
| 2004 |
Khorana N, Pullagurla MR, Dukat M, Young R, Glennon RA. Stimulus effects of three sulfur-containing psychoactive agents Pharmacology Biochemistry and Behavior. 78: 821-826. PMID 15301941 DOI: 10.1016/J.Pbb.2004.05.021 |
0.788 |
|
| 2004 |
Pullagurla M, Bondareva T, Young R, Glennon RA. Modulation of the stimulus effects of (+)amphetamine by the 5-HT 6 antagonist MS-245 Pharmacology Biochemistry and Behavior. 78: 263-268. PMID 15219766 DOI: 10.1016/J.Pbb.2004.03.017 |
0.831 |
|
| 2004 |
Pullagurla M, Bondareva T, Young R, Glennon RA. Modulation of the stimulus effects of (+)amphetamine by the 5-HT 6 antagonist MS-245 Pharmacology Biochemistry and Behavior. 78: 263-268. PMID 15219766 DOI: 10.1016/j.pbb.2004.03.017 |
0.329 |
|
| 2004 |
Dukat M, Taroua M, Dahdouh A, Siripurapu U, Damaj MI, Martin BR, Glennon RA. (+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents. Bioorganic & Medicinal Chemistry Letters. 14: 3651-4. PMID 15203136 DOI: 10.1016/J.Bmcl.2004.05.020 |
0.808 |
|
| 2004 |
Dukat M, Taroua M, Dahdouh A, Siripurapu U, Damaj MI, Martin BR, Glennon RA. (+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents. Bioorganic & Medicinal Chemistry Letters. 14: 3651-4. PMID 15203136 DOI: 10.1016/J.Bmcl.2004.05.020 |
0.808 |
|
| 2004 |
Khorana N, Pullagurla MR, Young R, Glennon RA. Comparison of the discriminative stimulus effects of 3,4- methylenedioxymethamphetamine (MDMA) and cocaine: Asymmetric generalization Drug and Alcohol Dependence. 74: 281-287. PMID 15194206 DOI: 10.1016/J.Drugalcdep.2004.01.005 |
0.788 |
|
| 2004 |
Dukat M, Smith C, Herrick-Davis K, Teitler M, Glennon RA. Binding of tryptamine analogs at h5-HT1E receptors: A structure-affinity investigation Bioorganic and Medicinal Chemistry. 12: 2545-2552. PMID 15110837 DOI: 10.1016/J.Bmc.2004.03.026 |
0.53 |
|
| 2004 |
Peddi S, Roth BL, Glennon RA, Westkaemper RB. Structural determinants for high 5-HT(2A) receptor affinity of spiro[9,10-dihydroanthracene]-9,3(')-pyrrolidine (SpAMDA). Bioorganic & Medicinal Chemistry Letters. 14: 2279-83. PMID 15081025 DOI: 10.1016/J.BMCL.2004.02.014 |
0.434 |
|
| 2004 |
Peddi S, Roth BL, Glennon RA, Westkaemper RB. Structural determinants for high 5-HT(2A) receptor affinity of spiro[9,10-dihydroanthracene]-9,3(')-pyrrolidine (SpAMDA). Bioorganic & Medicinal Chemistry Letters. 14: 2279-83. PMID 15081025 DOI: 10.1016/J.BMCL.2004.02.014 |
0.434 |
|
| 2004 |
Glennon RA, Ismaiel AM, Ablordeppey S, El-Ashmawy M, Fisher JB. Thioxanthene-derived analogs as sigma(1) receptor ligands. Bioorganic & Medicinal Chemistry Letters. 14: 2217-20. PMID 15081012 DOI: 10.1016/J.Bmcl.2004.02.018 |
0.339 |
|
| 2004 |
Glennon RA, Ismaiel AM, Ablordeppey S, El-Ashmawy M, Fisher JB. Thioxanthene-derived analogs as sigma(1) receptor ligands. Bioorganic & Medicinal Chemistry Letters. 14: 2217-20. PMID 15081012 DOI: 10.1016/J.Bmcl.2004.02.018 |
0.339 |
|
| 2004 |
Chang-Fong J, Rangisetty JB, Dukat M, Setola V, Raffay T, Roth B, Glennon RA. 1,2,3,4-Tetrahydrocarbazoles as 5-HT6 serotonin receptor ligands Bioorganic and Medicinal Chemistry Letters. 14: 1961-1964. PMID 15050637 DOI: 10.1016/J.Bmcl.2004.01.071 |
0.584 |
|
| 2004 |
Chang-Fong J, Rangisetty JB, Dukat M, Setola V, Raffay T, Roth B, Glennon RA. 1,2,3,4-Tetrahydrocarbazoles as 5-HT6 serotonin receptor ligands Bioorganic and Medicinal Chemistry Letters. 14: 1961-1964. PMID 15050637 DOI: 10.1016/j.bmcl.2004.01.071 |
0.429 |
|
| 2004 |
Glennon RA, Dukat M. α4β2 nACh Receptor pharmacophore models Bioorganic and Medicinal Chemistry Letters. 14: 1841-1844. PMID 15050612 DOI: 10.1016/J.Bmcl.2003.07.035 |
0.334 |
|
| 2004 |
Chang-Fong J, Tyacke RJ, Lau A, Westaway J, Hudson AL, Glennon RA. Pyrazino[1,2-a]indoles as novel high-affinity and selective imidazoline I2 receptor ligands Bioorganic and Medicinal Chemistry Letters. 14: 1003-1005. PMID 15013010 DOI: 10.1016/J.Bmcl.2003.12.033 |
0.536 |
|
| 2004 |
Glennon RA, Grella B, Tyacke RJ, Lau A, Westaway J, Hudson AL. Binding of β-carbolines at imidazoline I2 receptors: A structure-affinity investigation Bioorganic and Medicinal Chemistry Letters. 14: 999-1002. PMID 15013009 DOI: 10.1016/J.Bmcl.2003.11.078 |
0.82 |
|
| 2004 |
Glennon RA. Medicinal Chemistry of α4β2 Nicotinic Cholinergic Receptor Ligands Progress in Medicinal Chemistry. 42: 55-123. PMID 15003719 DOI: 10.1016/S0079-6468(04)42002-5 |
0.423 |
|
| 2004 |
Glennon RA, Dukat M, Liao L. Musings on alpha4beta2 nicotinic acetylcholine (nACh) receptor pharmacophore models. Current Topics in Medicinal Chemistry. 4: 631-44. PMID 14965299 DOI: 10.2174/1568026043451122 |
0.416 |
|
| 2004 |
Glennon RA, Grella B, Tyacke RJ, Lau A, Westaway J, Hudson AL. Binding of an imidazopyridoindole at imidazoline I2 receptors Bioorganic and Medicinal Chemistry Letters. 14: 527-529. PMID 14698196 DOI: 10.1016/J.Bmcl.2003.09.092 |
0.815 |
|
| 2004 |
Glennon RA, Grella B, Tyacke RJ, Lau A, Westaway J, Hudson AL. Binding of an imidazopyridoindole at imidazoline I2 receptors Bioorganic and Medicinal Chemistry Letters. 14: 527-529. PMID 14698196 DOI: 10.1016/j.bmcl.2003.09.092 |
0.319 |
|
| 2004 |
Dogruer D, Lee M, Dukat M, Damaj MI, Martin BR, Glennon RA. 3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors. Bioorganic & Medicinal Chemistry Letters. 14: 523-6. PMID 14698195 DOI: 10.1016/J.Bmcl.2003.10.033 |
0.33 |
|
| 2004 |
Dogruer D, Lee M, Dukat M, Damaj MI, Martin BR, Glennon RA. 3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors. Bioorganic & Medicinal Chemistry Letters. 14: 523-6. PMID 14698195 DOI: 10.1016/J.Bmcl.2003.10.033 |
0.33 |
|
| 2003 |
Peddi S, Roth BL, Glennon RA, Westkaemper RB. Spiro[9,10-dihydroanthracene]-9,3'-pyrrolidine-a structurally unique tetracyclic 5-HT2A receptor antagonist. European Journal of Pharmacology. 482: 335-7. PMID 14660041 DOI: 10.1016/J.Ejphar.2003.09.059 |
0.452 |
|
| 2003 |
Peddi S, Roth BL, Glennon RA, Westkaemper RB. Spiro[9,10-dihydroanthracene]-9,3'-pyrrolidine-a structurally unique tetracyclic 5-HT2A receptor antagonist. European Journal of Pharmacology. 482: 335-7. PMID 14660041 DOI: 10.1016/J.Ejphar.2003.09.059 |
0.452 |
|
| 2003 |
Grella B, Teitler M, Smith C, Herrick-Davis K, Glennon RA. Binding of β-carbolines at 5-HT2 serotonin receptors Bioorganic and Medicinal Chemistry Letters. 13: 4421-4425. PMID 14643338 DOI: 10.1016/J.Bmcl.2003.09.027 |
0.848 |
|
| 2003 |
Grella B, Teitler M, Smith C, Herrick-Davis K, Glennon RA. Binding of β-carbolines at 5-HT2 serotonin receptors Bioorganic and Medicinal Chemistry Letters. 13: 4421-4425. PMID 14643338 DOI: 10.1016/j.bmcl.2003.09.027 |
0.427 |
|
| 2003 |
Simsek R, Chang-Fong J, Lee M, Dukat M, Imad Damaj M, Martin BR, Glennon RA. Quaternary ammonium 3-(aminoethoxy)pyridines as antinociceptive agents. Bioorganic & Medicinal Chemistry Letters. 13: 2917-20. PMID 14611857 DOI: 10.1016/S0960-894X(03)00585-7 |
0.308 |
|
| 2003 |
Simsek R, Chang-Fong J, Lee M, Dukat M, Imad Damaj M, Martin BR, Glennon RA. Quaternary ammonium 3-(aminoethoxy)pyridines as antinociceptive agents. Bioorganic & Medicinal Chemistry Letters. 13: 2917-20. PMID 14611857 DOI: 10.1016/S0960-894X(03)00585-7 |
0.308 |
|
| 2003 |
Glennon RA, Daoud MK, Dukat MS, Teitler M, Herrick-Davis K, Purohit A, Syed H. Arylguanidine and arylbiguanide binding at 5-HT3 serotonin receptors: A QSAR study Bioorganic and Medicinal Chemistry. 11: 4449-4454. PMID 13129581 DOI: 10.1016/S0968-0896(03)00488-7 |
0.539 |
|
| 2003 |
Glennon RA, Daoud MK, Dukat MS, Teitler M, Herrick-Davis K, Purohit A, Syed H. Arylguanidine and arylbiguanide binding at 5-HT3 serotonin receptors: A QSAR study Bioorganic and Medicinal Chemistry. 11: 4449-4454. PMID 13129581 DOI: 10.1016/S0968-0896(03)00488-7 |
0.468 |
|
| 2003 |
Eckler JR, Chang-Fong J, Rabin RA, Smith C, Teitler M, Glennon RA, Winter JC. Behavioral characterization of 2-O-desmethyl and 5-O-desmethyl metabolites of the phenylethylamine hallucinogen DOM. Pharmacology, Biochemistry, and Behavior. 75: 845-52. PMID 12957227 DOI: 10.1016/S0091-3057(03)00159-X |
0.433 |
|
| 2003 |
Pullagurla MR, Dukat M, Setola V, Roth B, Glennon RA. N1-benzenesulfonylgramine and N1-benzenesulfonylskatole: novel 5-HT6 receptor ligand templates. Bioorganic & Medicinal Chemistry Letters. 13: 3355-9. PMID 12951125 DOI: 10.1016/S0960-894X(03)00612-7 |
0.848 |
|
| 2003 |
Khorana N, Smith C, Herrick-Davis K, Purohit A, Teitler M, Grella B, Dukat M, Glennon RA. Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors. Journal of Medicinal Chemistry. 46: 3930-7. PMID 12930153 DOI: 10.1021/Jm030080S |
0.84 |
|
| 2003 |
Bondarev ML, Bondareva TS, Young R, Glennon RA. Behavioral and biochemical investigations of bupropion metabolites. European Journal of Pharmacology. 474: 85-93. PMID 12909199 DOI: 10.1016/S0014-2999(03)02010-7 |
0.387 |
|
| 2003 |
Peddi S, Roth BL, Glennon RA, Westkaemper RB. Ring substituted analogues of 5-aminomethyl-10,11-dihydro-dibenzo[a,d]cycloheptene (AMDH): potential modes of binding to the 5-HT(2A) receptor. Bioorganic & Medicinal Chemistry Letters. 13: 2565-8. PMID 12852967 DOI: 10.1016/S0960-894X(03)00504-3 |
0.525 |
|
| 2003 |
Glennon RA. Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). Journal of Medicinal Chemistry. 46: 2795-812. PMID 12825922 DOI: 10.1021/Jm030030N |
0.487 |
|
| 2003 |
Dukat M, Glennon RA. Epibatidine: impact on nicotinic receptor research. Cellular and Molecular Neurobiology. 23: 365-78. PMID 12825833 DOI: 10.1023/A:1023692705700 |
0.334 |
|
| 2003 |
Setola V, Hufeisen SJ, Grande-Allen KJ, Vesely I, Glennon RA, Blough B, Rothman RB, Roth BL. 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro. Molecular Pharmacology. 63: 1223-9. PMID 12761331 DOI: 10.1124/Mol.63.6.1223 |
0.426 |
|
| 2003 |
Rahman AA, Daoud MK, Dukat M, Herrick-Davis K, Purohit A, Teitler M, do Amaral AT, Malvezzi A, Glennon RA. Conformationally-restricted analogues and partition coefficients of the 5-HT3 serotonin receptor ligands meta-chlorophenylbiguanide (mCPBG) and meta-chlorophenylguanidine (mCPG). Bioorganic & Medicinal Chemistry Letters. 13: 1119-23. PMID 12643925 DOI: 10.1016/S0960-894X(03)00044-1 |
0.48 |
|
| 2003 |
Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA. Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors. Bioorganic & Medicinal Chemistry Letters. 13: 733-5. PMID 12639569 DOI: 10.1016/S0960-894X(02)01031-4 |
0.396 |
|
| 2003 |
Khorana N, Purohit A, Herrick-Davis K, Teitler M, Glennon RA. gamma-Carbolines: binding at 5-HT5A serotonin receptors. Bioorganic & Medicinal Chemistry. 11: 717-22. PMID 12538001 DOI: 10.1016/S0968-0896(02)00527-8 |
0.8 |
|
| 2003 |
Pullagurla MR, Dukat MS, Setola V, Roth B, Glennon RA. N1-benzenesulfonylgramine and N 1-benzenesulfonylskatole: Novel 5-HT6 receptor ligand templates Bioorganic and Medicinal Chemistry Letters. 13: 3355-3359. DOI: 10.1016/S0960-894X(03)00612-7 |
0.838 |
|
| 2003 |
Pullagurla MR, Dukat MS, Setola V, Roth B, Glennon RA. N1-benzenesulfonylgramine and N 1-benzenesulfonylskatole: Novel 5-HT6 receptor ligand templates Bioorganic and Medicinal Chemistry Letters. 13: 3355-3359. DOI: 10.1016/S0960-894X(03)00612-7 |
0.439 |
|
| 2003 |
Glennon RA. Higher-End Serotonin Receptors: 5-HT5, 5-HT6, and 5-HT7 Cheminform. 34. DOI: 10.1002/CHIN.200339253 |
0.386 |
|
| 2002 |
Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA. Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding. Journal of Medicinal Chemistry. 45: 4724-31. PMID 12361399 DOI: 10.1021/Jm020188S |
0.449 |
|
| 2002 |
Dukat M, El-Zahabi M, Ferretti G, Damaj MI, Martin BR, Young R, Glennon RA. (-)6-n-Propylnicotine antagonizes the antinociceptive effects of (-)nicotine. Bioorganic & Medicinal Chemistry Letters. 12: 3005-7. PMID 12270194 DOI: 10.1016/S0960-894X(02)00614-5 |
0.41 |
|
| 2002 |
Lee M, Dukat M, Liao L, Flammia D, Damaj MI, Martin B, Glennon RA. A comparison of the binding of three series of nicotinic ligands. Bioorganic & Medicinal Chemistry Letters. 12: 1989-92. PMID 12113825 DOI: 10.1016/S0960-894X(02)00298-6 |
0.39 |
|
| 2002 |
Ablordeppey SY, Fischer JB, Law H, Glennon RA. Probing the proposed phenyl-A region of the sigma-1 receptor. Bioorganic & Medicinal Chemistry. 10: 2759-65. PMID 12057665 DOI: 10.1016/S0968-0896(02)00096-2 |
0.432 |
|
| 2002 |
Westkaemper RB, Glennon RA. Application of ligand SAR, receptor modeling and receptor mutagenesis to the discovery and development of a new class of 5-HT(2A) ligands. Current Topics in Medicinal Chemistry. 2: 575-98. PMID 12052195 DOI: 10.2174/1568026023393741 |
0.553 |
|
| 2002 |
Glennon RA, Metwally K, Dukat M, Ismaiel AM, De los Angeles J, Herndon J, Teitler M, Khorana N. Ketanserin and spiperone as templates for novel serotonin 5-HT(2A) antagonists. Current Topics in Medicinal Chemistry. 2: 539-58. PMID 12052193 DOI: 10.2174/1568026023393787 |
0.805 |
|
| 2002 |
Young R, Glennon RA. Nicotine and bupropion share a similar discriminative stimulus effect. European Journal of Pharmacology. 443: 113-8. PMID 12044800 DOI: 10.1016/S0014-2999(02)01554-6 |
0.32 |
|
| 2002 |
Runyon SP, Peddi S, Savage JE, Roth BL, Glennon RA, Westkaemper RB. Geometry-affinity relationships of the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene. Journal of Medicinal Chemistry. 45: 1656-64. PMID 11931619 DOI: 10.1021/Jm010354G |
0.492 |
|
| 2002 |
Glennon RA, Young R, Rangisetty JB. Further characterization of the stimulus properties of 5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline. Pharmacology, Biochemistry, and Behavior. 72: 379-87. PMID 11900809 DOI: 10.1016/S0091-3057(01)00768-7 |
0.369 |
|
| 2002 |
Glennon RA, Young R. Effect of 1-(3,4-methylenedioxyphenyl)-2-aminopropane and its optical isomers in PMMA-trained rats. Pharmacology, Biochemistry, and Behavior. 72: 307-11. PMID 11900801 DOI: 10.1016/S0091-3057(01)00770-5 |
0.347 |
|
| 2002 |
Dukat M, Young R, Glennon RA. Effect of PMA optical isomers and 4-MTA in PMMA-trained rats. Pharmacology, Biochemistry, and Behavior. 72: 299-305. PMID 11900800 DOI: 10.1016/S0091-3057(01)00776-6 |
0.359 |
|
| 2002 |
Dukat M, Damaj IM, Young R, Vann R, Collins AC, Marks MJ, Martin BR, Glennon RA. Functional diversity among 5-substituted nicotine analogs; in vitro and in vivo investigations. European Journal of Pharmacology. 435: 171-80. PMID 11821023 DOI: 10.1016/S0014-2999(01)01570-9 |
0.392 |
|
| 2002 |
Young R, Glennon RA. The stimulus effect of 5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline is similar to that of cocaine but different from that of amphetamine. Pharmacology, Biochemistry, and Behavior. 71: 205-13. PMID 11812524 DOI: 10.1016/S0091-3057(01)00666-9 |
0.348 |
|
| 2002 |
Chang-Fong J, Addo J, Dukat M, Smith C, Mitchell NA, Herrick-Davis K, Teitler M, Glennon RA. Evaluation of isotryptamine derivatives at 5-HT(2) serotonin receptors. Bioorganic & Medicinal Chemistry Letters. 12: 155-8. PMID 11755343 DOI: 10.1016/S0960-894X(01)00713-2 |
0.529 |
|
| 2001 |
Rangisetty JB, Dukat M, Dowd CS, Herrick-Davis K, DuPre A, Gadepalli S, Teitler M, Kelley CR, Sharif NA, Glennon RA. 1-[2-methoxy-5-(3-phenylpropyl)]-2-aminopropane unexpectedly shows 5-HT(2A) serotonin receptor affinity and antagonist character. Journal of Medicinal Chemistry. 44: 3283-91. PMID 11563927 DOI: 10.1021/Jm0100739 |
0.551 |
|
| 2001 |
Husbands SM, Glennon RA, Gorgerat S, Gough R, Tyacke R, Crosby J, Nutt DJ, Lewis JW, Hudson AL. beta-carboline binding to imidazoline receptors. Drug and Alcohol Dependence. 64: 203-8. PMID 11543990 DOI: 10.1016/S0376-8716(01)00123-5 |
0.45 |
|
| 2001 |
Rangisetty JB, Bondarev ML, Chang-Fong J, Young R, Glennon RA. PMMA-stimulus generalization to the optical isomers of MBDB and 3,4-DMA. Pharmacology, Biochemistry, and Behavior. 69: 261-7. PMID 11420094 DOI: 10.1016/S0091-3057(01)00530-5 |
0.344 |
|
| 2001 |
Dukat M, Choi YN, Teitler M, Du Pre A, Herrick-Davis K, Smith C, Glennon RA. The binding of arylguanidines at 5-HT(3) serotonin receptors: a structure-affinity investigation. Bioorganic & Medicinal Chemistry Letters. 11: 1599-603. PMID 11412989 DOI: 10.1016/S0960-894X(01)00291-8 |
0.566 |
|
| 2001 |
Prisinzano T, Law H, Dukat M, Slassi A, MaClean N, Demchyshyn L, Glennon RA. Imidazoline-modified benzylimidazolines as h5-HT(1D/1B) serotonergic ligands. Bioorganic & Medicinal Chemistry. 9: 613-9. PMID 11310595 DOI: 10.1016/S0968-0896(00)00275-3 |
0.665 |
|
| 2001 |
Runyon SP, Savage JE, Taroua M, Roth BL, Glennon RA, Westkaemper RB. Influence of chain length and N-alkylation on the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene. Bioorganic & Medicinal Chemistry Letters. 11: 655-8. PMID 11266163 DOI: 10.1016/S0960-894X(01)00023-3 |
0.527 |
|
| 2001 |
Westkaemper RB, Runyon SP, Savage JE, Roth BL, Glennon RA. Exploring the relationship between binding modes of 9-(aminomethyl)-9,10-dihydroanthracene and cyproheptadine analogues at the 5-HT2A serotonin receptor. Bioorganic & Medicinal Chemistry Letters. 11: 563-6. PMID 11229772 DOI: 10.1016/S0960-894X(01)00010-5 |
0.476 |
|
| 2001 |
Prisinzano T, Law H, Slassi A, Maclean N, Demchyshyn L, Glennon RA. QSAR studies on 2-(benzyl)imidazoline analogs as h5-HT1D/1B serotonin receptor ligands Medicinal Chemistry Research. 10: 309-317. |
0.309 |
|
| 2000 |
Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA. Chain-lengthened and imidazoline analogues of nicotine. Bioorganic & Medicinal Chemistry Letters. 10: 2665-8. PMID 11128647 DOI: 10.1016/S0960-894X(00)00541-2 |
0.343 |
|
| 2000 |
Tsai Y, Dukat M, Slassi A, MacLean N, Demchyshyn L, Savage JE, Roth BL, Hufesein S, Lee M, Glennon RA. N1-(Benzenesulfonyl)tryptamines as novel 5-HT6 antagonists. Bioorganic & Medicinal Chemistry Letters. 10: 2295-9. PMID 11055342 DOI: 10.1016/S0960-894X(00)00453-4 |
0.57 |
|
| 2000 |
Ablordeppey SY, Fischer JB, Glennon RA. Is a nitrogen atom an important pharmacophoric element in sigma ligand binding? Bioorganic & Medicinal Chemistry. 8: 2105-11. PMID 11003156 DOI: 10.1016/S0968-0896(00)00148-6 |
0.405 |
|
| 2000 |
Dowd CS, Herrick-Davis K, Egan C, DuPre A, Smith C, Teitler M, Glennon RA. 1-[4-(3-Phenylalkyl)phenyl]-2-aminopropanes as 5-HT(2A) partial agonists Journal of Medicinal Chemistry. 43: 3074-3084. PMID 10956215 DOI: 10.1021/Jm9906062 |
0.52 |
|
| 2000 |
Glennon RA, Dukat M, Grella B, Hong SS, Costantino L, Teitler M, Smith C, Egan C, Davis K, Mattson MV. Binding of β-carbolines and related agents at serotonin (5-HT2 and 5- HT(1A)), dopamine (D2) and benzodiazepine receptors Drug and Alcohol Dependence. 60: 121-132. PMID 10940539 DOI: 10.1016/S0376-8716(99)00148-9 |
0.852 |
|
| 2000 |
Dukat M, Young R, Darmani NN, Ahmed B, Glennon RA. The 5-HT3 agent N-(3-chlorophenyl)guanidine (MD-354) serves as a discriminative stimulus in rats and displays partial agonist character in a shrew emesis assay Psychopharmacology. 150: 200-207. PMID 10907673 DOI: 10.1007/S002130000410 |
0.543 |
|
| 2000 |
Young R, Glennon RA. Stimulus effects of phenylpropanolamine optical isomers in (+)amphetamine-trained rats Pharmacology Biochemistry and Behavior. 66: 489-494. PMID 10899360 DOI: 10.1016/S0091-3057(00)00173-8 |
0.305 |
|
| 2000 |
Glennon RA, Young R. MDMA stimulus generalization to the 5-HT(1A) serotonin agonist 8-hydroxy-2- (di-n-propylamino)tetralin Pharmacology Biochemistry and Behavior. 66: 483-488. PMID 10899359 DOI: 10.1016/S0091-3057(00)00174-X |
0.536 |
|
| 2000 |
Kristiansen K, Kroeze WK, Willins DL, Gelber EI, Savage JE, Glennon RA, Roth BL. A highly conserved aspartic acid (Asp-155) anchors the terminal amine moiety of tryptamines and is involved in membrane targeting of the 5-HT(2A) serotonin receptor but does not participate in activation via a "salt-bridge disruption" mechanism. The Journal of Pharmacology and Experimental Therapeutics. 293: 735-46. PMID 10869371 |
0.402 |
|
| 2000 |
Glennon RA, Young R. (+)Amphetamine-stimulus generalization to an herbal ephedrine product Pharmacology Biochemistry and Behavior. 65: 655-658. PMID 10764918 DOI: 10.1016/S0091-3057(99)00238-5 |
0.316 |
|
| 2000 |
Glennon RA, Lee M, Rangisetty JB, Dukat M, Roth BL, Savage JE, McBride A, Rauser L, Hufeisen S, Lee DK. 2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors. Journal of Medicinal Chemistry. 43: 1011-8. PMID 10715164 DOI: 10.1021/Jm990550B |
0.553 |
|
| 2000 |
Glennon RA, Dukat M. Central nicotinic receptor ligands and pharmacophores Pharmacochemistry Library. 31: 103-114. DOI: 10.1016/S0031-6865(99)00022-9 |
0.428 |
|
| 2000 |
Lee M, Rangisetty JB, Dukat M, Slassi A, Maclean N, Lee DKH, Glennon RA. 5-HT6 serotonin receptor binding affinities of N1-benzenesulfonyl and related tryptamines Medicinal Chemistry Research. 10: 230-242. |
0.498 |
|
| 1999 |
Young R, Bondarev M, Glennon RA. An examination of isomeric phenylpropanolamines in (-)ephedrine-trained rats Drug and Alcohol Dependence. 57: 1-6. PMID 10617308 DOI: 10.1016/S0376-8716(99)00052-6 |
0.322 |
|
| 1999 |
Young R, Dukat M, Malmusi L, Glennon RA. Stimulus properties of PMMA: Effect of optical isomers and conformational restriction Pharmacology Biochemistry and Behavior. 64: 449-453. PMID 10515329 DOI: 10.1016/S0091-3057(99)00060-X |
0.327 |
|
| 1999 |
Westkaemper RB, Runyon SP, Bondarev ML, Savage JE, Roth BL, Glennon RA. 9-(Aminomethyl)-9,10-dihydroanthracene is a novel and unlikely 5-HT2A receptor antagonist. European Journal of Pharmacology. 380: R5-7. PMID 10513561 DOI: 10.1016/S0014-2999(99)00525-7 |
0.473 |
|
| 1999 |
Flammia D, Dukat M, Damaj MI, Martin B, Glennon RA. Lobeline: Structure-affinity investigation of nicotinic acetylcholinergic receptor binding Journal of Medicinal Chemistry. 42: 3726-3731. PMID 10479304 DOI: 10.1021/Jm990286M |
0.402 |
|
| 1999 |
Nelson DL, Lucaites VL, Wainscott DB, Glennon RA. Comparisons of hallucinogenic phenylisopropylamine binding affinities at cloned human 5-HT2A, -HT(2B) and 5-HT2C receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 359: 1-6. PMID 9933142 DOI: 10.1007/Pl00005315 |
0.472 |
|
| 1999 |
Westkaemper RB, Hyde EG, Choudhary MS, Khan N, Gelbar EI, Glennon RA, Roth BL. Engineering a region of bulk tolerance in the 5-ht(2a) receptor European Journal of Medicinal Chemistry. 34: 441-447. DOI: 10.1016/S0223-5234(99)80094-4 |
0.483 |
|
| 1999 |
Cheng YX, Dukat M, Dowd M, Fiedler W, Martin B, Damaj MI, Glennon RA. Synthesis and binding of 6,7,8,9-tetrahydro-5H-pyrido[3,4-d]azepine and related ring-opened analogs at central nicotinic receptors European Journal of Medicinal Chemistry. 34: 177-190. DOI: 10.1016/S0223-5234(99)80051-8 |
0.448 |
|
| 1999 |
Dukat M, Dowd M, Damaj MI, Martin B, El-Zahabi MA, Glennon RA. Synthesis, receptor binding and QSAR studies on 6-substituted nicotine derivatives as cholinergic ligands European Journal of Medicinal Chemistry. 34: 31-40. DOI: 10.1016/S0223-5234(99)80038-5 |
0.421 |
|
| 1999 |
Hong S, Dukat M, Teitler M, Egan C, Dupre A, Herrick-Davis K, Glennon RA. 5,8-Dimethoxyharmalan: Actions at 5-HT(2A) serotonin receptors Medicinal Chemistry Research. 9: 374-388. |
0.408 |
|
| 1999 |
Khorana N, Bondarev M, Dukat M, Herrick-Davis K, Egan C, DuPre A, Smith C, Teitler M, Glennon RA. Binding of spiperone analogs at 5-HT(2A) serotonin receptors Medicinal Chemistry Research. 9: 657-667. |
0.782 |
|
| 1999 |
Glennon RA, Bondarev M, Roth B. 5-HT6 serotonin receptor binding of indolealkylamines: A preliminary structure-affinity investigation Medicinal Chemistry Research. 9: 108-117. |
0.472 |
|
| 1998 |
Young R, Glennon RA. Discriminative stimulus effects of S(-)-methcathinone (CAT): A potent stimulant drug of abuse Psychopharmacology. 140: 250-256. PMID 9877004 DOI: 10.1007/S002130050765 |
0.312 |
|
| 1998 |
Metwally KA, Dukat M, Egan CT, Smith C, DuPre A, Gauthier CB, Herrick-Davis K, Teitler M, Glennon RA. Spiperone: Influence of spiro ring substituents on 5-HT(2A) serotonin receptor binding Journal of Medicinal Chemistry. 41: 5084-5093. PMID 9836624 DOI: 10.1021/Jm980452A |
0.599 |
|
| 1998 |
Young R, Glennon RA. Discriminative stimulus properties of (-)ephedrine Pharmacology Biochemistry and Behavior. 60: 771-775. PMID 9678664 DOI: 10.1016/S0091-3057(98)00055-0 |
0.32 |
|
| 1998 |
Grella B, Dukat M, Young R, Teitler M, Herrick-Davis K, Gauthier CB, Glennon RA. Investigation of hallucinogenic and related β-carbolines Drug and Alcohol Dependence. 50: 99-107. PMID 9649961 DOI: 10.1016/S0376-8716(97)00163-4 |
0.449 |
|
| 1998 |
Law H, Dukat M, Teitler M, Lee DKH, Mazzocco L, Kamboj R, Rampersad V, Prisinzano T, Glennon RA. Benzylimidazolines as h5-HT(1B/1D) serotonin receptor ligands: A structure-affinity investigation Journal of Medicinal Chemistry. 41: 2243-2251. PMID 9632357 DOI: 10.1021/Jm970513P |
0.676 |
|
| 1998 |
Egan CT, Herrick-Davis K, Miller K, Glennon RA, Teitler M. Agonist activity of LSD and lisuride at cloned 5HT(2A) and 5HT(2C) receptors Psychopharmacology. 136: 409-414. PMID 9600588 DOI: 10.1007/S002130050585 |
0.494 |
|
| 1998 |
Glennon RA. Serotonin Receptors and Their Ligands Edited by B. Olivier, I. Van Wijngaarden, and W. Soudin. Elsevier, Amsterdam. 1997. × + 367 pp. 17 × 24.5 cm. ISBN 0-444-82041-8. $297.00. Journal of Medicinal Chemistry. 41: 3917-3918. DOI: 10.1021/Jm980386C |
0.353 |
|
| 1998 |
Ablordeppey SY, El-Ashmawy M, Fischer JB, Glennon RA. A CoMFA investigation of sigma receptor binding affinity: Reexamination of a spurious sigma ligand European Journal of Medicinal Chemistry. 33: 625-633. DOI: 10.1016/S0223-5234(98)80021-4 |
0.408 |
|
| 1998 |
Bondarev M, Iwamura T, Hynd D, Mazzocco L, Lee DKH, Dukat M, Glennon RA. Aryloxyethylamines as h5-HT(1D) serotonin receptor ligands Medicinal Chemistry Research. 8: 333-342. |
0.406 |
|
| 1997 |
Ismaiel AM, Dukat M, Law H, Kamboj R, Fan E, Lee DKH, Mazzocco L, Buekschkens D, Teitler M, Pierson ME, Glennon RA. 2-(1-naphthyloxy)ethylamines with enhanced affinity for human 5-HT(1Dβ) (h5-HT(1B)) serotonin receptors Journal of Medicinal Chemistry. 40: 4415-4419. PMID 9435911 DOI: 10.1021/Jm970507T |
0.535 |
|
| 1997 |
Dal Cason TA, Young R, Glennon RA. Cathinone: An investigation of several N-alkyl and methylenedioxy-substituted analogs Pharmacology Biochemistry and Behavior. 58: 1109-1116. PMID 9408221 DOI: 10.1016/S0091-3057(97)00323-7 |
0.401 |
|
| 1997 |
Glennon RA, Young R, Dukat M, Cheng Y. Initial characterization of PMMA as a discriminative stimulus Pharmacology Biochemistry and Behavior. 57: 151-158. PMID 9164566 DOI: 10.1016/S0091-3057(96)00306-1 |
0.341 |
|
| 1997 |
Young R, Glennon RA. Cocaine - Stimulus generalization to MDA optical isomores: A reevaluation Pharmacology Biochemistry and Behavior. 57: 115-118. PMID 9164561 DOI: 10.1016/S0091-3057(96)00352-8 |
0.305 |
|
| 1997 |
Young R, Darmani NA, Elder EL, Dumas D, Glennon RA. Clobenzorex: Evidence for amphetamine-like behavioral actions Pharmacology Biochemistry and Behavior. 56: 311-316. PMID 9050090 DOI: 10.1016/S0091-3057(96)00329-2 |
0.35 |
|
| 1997 |
Teitler M, Scheick C, Howard P, Sullivan JE, Iwamura T, Glennon RA. 5-HT5A serotonin receptor binding: A preliminary structure-affinity investigation Medicinal Chemistry Research. 7: 207-218. |
0.411 |
|
| 1996 |
Dukat M, Abdel-Rahman AA, Ismaiel AM, Ingher S, Teitler M, Gyermek L, Glennon RA. Structure-activity relationships for the binding of arylpiperazines and arylbiguanides at 5-HT3 serotonin receptors Journal of Medicinal Chemistry. 39: 4017-4026. PMID 8831767 DOI: 10.1021/Jm9603936 |
0.559 |
|
| 1996 |
Glennon RA, Hong SS, Bondarev M, Law H, Dukat M, Rakhit S, Power P, Fan E, Kinneau D, Kamboj R, Teitler M, Herrick-Davis K, Smith C. Binding of O-alkyl derivatives of serotonin at human 5-HT1Dβ receptors Journal of Medicinal Chemistry. 39: 314-322. PMID 8568822 DOI: 10.1021/Jm950498T |
0.482 |
|
| 1996 |
Dukat M, Fiedler W, Dumas D, Damaj I, Martin BR, Rosecrans JA, James JR, Glennon RA. Pyrrolidine-modified and 6-substituted analogs of nicotine: A structure-affinity investigation European Journal of Medicinal Chemistry. 31: 875-888. DOI: 10.1016/S0223-5234(97)89850-9 |
0.429 |
|
| 1996 |
Imad Damaj M, Glassco W, Dukat M, May EL, Glennon RA, Martin BR. Pharmacology of novel nicotinic analogs Drug Development Research. 38: 177-187. DOI: 10.1002/(Sici)1098-2299(199607/08)38:3/4<177::Aid-Ddr6>3.0.Co;2-J |
0.383 |
|
| 1996 |
Ismaiel AM, Dukat M, Nelson DL, Lucaites VL, Glennon RA. Binding of N2-substituted pyrido[4,3-b]indole analogs of spiperone at human 5-HT2A, 5-HT2B, and 5-HT2C serotonin receptors Medicinal Chemistry Research. 6: 197-211. |
0.434 |
|
| 1995 |
Ismaiel AM, Arruda K, Teitler M, Glennon RA. Ketanserin analogues: The effect of structural modification on 5-HT2 serotonin receptor binding Journal of Medicinal Chemistry. 38: 1196-1202. PMID 7707322 DOI: 10.1021/Jm00007A016 |
0.545 |
|
| 1995 |
Glennon RA, Young R, Martin BR, Dal Cason TA. Methcathinone ("cat"): An enantiomeric potency comparison Pharmacology, Biochemistry and Behavior. 50: 601-606. PMID 7617707 DOI: 10.1016/0091-3057(94)00348-3 |
0.32 |
|
| 1994 |
Westkaemper RB, Glennon RA. Molecular modeling of the interaction of LSD and other hallucinogens with 5-HT2 receptors Nida Research Monograph. 146: 263-283. PMID 8742803 |
0.378 |
|
| 1994 |
Damaj MI, Glennon RA, Martin BR. Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice. Brain Research Bulletin. 33: 199-203. PMID 8275340 DOI: 10.1016/0361-9230(94)90252-6 |
0.424 |
|
| 1994 |
Glennon RA, Ablordeppey SY, Ismaiel AM, el-Ashmawy MB, Fischer JB, Howie KB. Structural features important for sigma 1 receptor binding. Journal of Medicinal Chemistry. 37: 1214-9. PMID 8164264 DOI: 10.1021/Jm00034A020 |
0.447 |
|
| 1994 |
Glennon RA, Hong SS, Dukat M, Teitler M, Davis K. 5-(Nonyloxy)tryptamine: A novel high-affinity 5-HTIDβ serotonin receptor agonist Journal of Medicinal Chemistry. 37: 2828-2830. PMID 8071931 DOI: 10.1021/Jm00044A001 |
0.509 |
|
| 1994 |
Glennon RA, Dukat M, El-Bermawy M, Law H, De Los Angeles J, Teitler M, King A, Herrick-Davis K. Influence of amine substituents on 5-HT2A versus 5-HT2C binding of phenylalkyl- and indolylalkylamines Journal of Medicinal Chemistry. 37: 1929-1935. PMID 8027974 DOI: 10.1021/Jm00039A004 |
0.506 |
|
| 1993 |
Young R, Glennon RA. Cocaine-stimulus generalization to two new designer drugs: methcathinone and 4-methylaminorex. Pharmacology, Biochemistry, and Behavior. 45: 229-31. PMID 8516363 DOI: 10.1016/0091-3057(93)90110-F |
0.319 |
|
| 1993 |
Ismaiel AM, De Los Angeles J, Teitler M, Ingher S, Glennon RA. Antagonism of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane stimulus with a newly identified 5-HT2- versus 5-HT1C-selective antagonist Journal of Medicinal Chemistry. 36: 2519-2525. PMID 8355253 DOI: 10.1021/Jm00069A010 |
0.564 |
|
| 1993 |
Glennon RA, Young R, Herndon JL. Antagonism of a (+)N-allylnormetazocine stimulus by (-)PPAP and several structurally related analogs Pharmacology, Biochemistry and Behavior. 45: 865-869. PMID 8105490 DOI: 10.1016/0091-3057(93)90133-E |
0.458 |
|
| 1993 |
Glennon RA, Higgs R, Young R, Issa H. Further studies on N-methyl-1(3,4-methylenedioxyphenyl)-2-aminopropane as a discriminative stimulus: antagonism by 5-hydroxytryptamine3 antagonists. Pharmacology, Biochemistry, and Behavior. 43: 1099-106. PMID 1361990 DOI: 10.1016/0091-3057(92)90488-2 |
0.45 |
|
| 1993 |
Abou-Gharbia M, Ablordeppey SY, Glennon RA. Chapter 1. Sigma Receptors and their Ligands: The Sigma Enigma Annual Reports in Medicinal Chemistry. 28: 1-10. DOI: 10.1016/S0065-7743(08)60871-4 |
0.464 |
|
| 1992 |
Glennon RA, Dukat M. Serotonin receptors and their ligands: a lack of selective agents. Pharmacology, Biochemistry, and Behavior. 40: 1009-17. PMID 1816555 DOI: 10.1016/0091-3057(91)90121-H |
0.517 |
|
| 1992 |
Darmani NA, Martin BR, Glennon RA. Repeated administration of low doses of cocaine enhances the sensitivity of 5-HT2 receptor function. Pharmacology, Biochemistry, and Behavior. 41: 519-27. PMID 1584831 DOI: 10.1016/0091-3057(92)90367-O |
0.426 |
|
| 1992 |
Glennon RA, Young R, Dukat M. 5-HT3 agonist 2-methylserotonin as a training drug in discrimination studies. Pharmacology, Biochemistry, and Behavior. 41: 361-4. PMID 1574526 DOI: 10.1016/0091-3057(92)90111-R |
0.506 |
|
| 1992 |
Young R, Glennon RA. Zacopride and its optical isomers produce stereoselective antagonism of a 2-methylserotonin discriminative stimulus. European Journal of Pharmacology. 212: 117-9. PMID 1555633 DOI: 10.1016/0014-2999(92)90083-G |
0.524 |
|
| 1992 |
Glennon RA, Raghupathi R, Bartyzel P, Teitler M, Leonhardt S. Binding of phenylalkylamine derivatives at 5-HT1C and 5-HT2 serotonin receptors: evidence for a lack of selectivity. Journal of Medicinal Chemistry. 35: 734-40. PMID 1542100 DOI: 10.1021/Jm00082A014 |
0.571 |
|
| 1992 |
Herndon JL, Ismaiel A, Ingher SP, Teitler M, Glennon RA. Ketanserin analogues: Structure-affinity relationships for 5-HT2 and 5-HT1C serotonin receptor binding Journal of Medicinal Chemistry. 35: 4903-4910. PMID 1479590 DOI: 10.1021/Jm00104A017 |
0.567 |
|
| 1992 |
Glennon RA, Higgs R. Investigation of MDMA-related agents in rats trained to discriminate MDMA from saline. Pharmacology, Biochemistry, and Behavior. 43: 759-63. PMID 1360162 DOI: 10.1016/0091-3057(92)90405-5 |
0.388 |
|
| 1992 |
Herndon JL, Pierson ME, Glennon RA. Mechanistic investigation of the stimulus properties of 1-(3-trifluoromethylphenyl) piperazine Pharmacology, Biochemistry and Behavior. 43: 739-748. PMID 1333084 DOI: 10.1016/0091-3057(92)90403-3 |
0.401 |
|
| 1992 |
Glennon RA. Concepts for the design of 5-HT1A serotonin agonists and antagonists Drug Development Research. 26: 251-274. DOI: 10.1002/Ddr.430260306 |
0.445 |
|
| 1991 |
Darmani NA, Martin BR, Pandey U, Glennon RA. Pharmacological characterization of ear-scratch response in mice as a behavioral model for selective 5-HT2-receptor agonists and evidence for 5-HT1B- and 5-HT2-receptor interactions. Pharmacology, Biochemistry, and Behavior. 37: 95-9. PMID 2263671 DOI: 10.1016/0091-3057(90)90047-L |
0.531 |
|
| 1991 |
Glennon RA, De Vry J, Spencer DG, Glaser T. Stimulus properties of tiflucarbine: a novel antidepressant agent. Pharmacology, Biochemistry, and Behavior. 37: 769-71. PMID 2151199 DOI: 10.1016/0091-3057(90)90561-U |
0.515 |
|
| 1991 |
Higgs RA, Glennon RA. Stimulus properties of ring-methyl amphetamine analogs. Pharmacology, Biochemistry, and Behavior. 37: 835-7. PMID 2093186 DOI: 10.1016/0091-3057(90)90571-X |
0.343 |
|
| 1991 |
Glennon RA, Darmani NA, Martin BR. Multiple populations of serotonin receptors may modulate the behavioral effects of serotonergic agents. Life Sciences. 48: 2493-8. PMID 2046474 DOI: 10.1016/0024-3205(91)90603-9 |
0.5 |
|
| 1991 |
Glennon RA, Smith JD, Ismaiel AM, el-Ashmawy M, Battaglia G, Fischer JB. Identification and exploitation of the sigma-opiate pharmacophore. Journal of Medicinal Chemistry. 34: 1094-8. PMID 1848295 DOI: 10.1021/Jm00107A033 |
0.422 |
|
| 1991 |
Westkaemper RB, Glennon RA. Approaches to molecular modeling studies and specific application to serotonin ligands and receptors Pharmacology, Biochemistry and Behavior. 40: 1019-1031. PMID 1816556 DOI: 10.1016/0091-3057(91)90122-I |
0.471 |
|
| 1991 |
Darmani NA, Martin BR, Pandey U, Glennon RA. Inhibition of 5-HT2 receptor-mediated head-twitch response by cocaine via indirect stimulation of adrenergic alpha 2 and serotonergic 5-HT1A receptors. Pharmacology, Biochemistry, and Behavior. 38: 353-7. PMID 1676173 DOI: 10.1016/0091-3057(91)90290-I |
0.509 |
|
| 1991 |
Glennon RA, Yousif MY, Ismaiel AM, el-Ashmawy MB, Herndon JL, Fischer JB, Server AC, Howie KJ. Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity sigma ligands. Journal of Medicinal Chemistry. 34: 3360-5. PMID 1662725 DOI: 10.1021/Jm00116A003 |
0.464 |
|
| 1991 |
Raghupathi RK, Rydelek-Fitzgerald L, Teitler M, Glennon RA. Analogues of the 5-HT1A serotonin antagonist 1-(2-methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine with reduced alpha 1-adrenergic affinity. Journal of Medicinal Chemistry. 34: 2633-8. PMID 1652026 DOI: 10.1021/Jm00112A043 |
0.487 |
|
| 1991 |
Glennon RA, Ismaiel AM, Smith JD, Yousif M, el-Ashmawy M, Herndon JL, Fischer JB, Howie KJ, Server AC. Binding of substituted and conformationally restricted derivatives of N-(3-phenyl-n-propyl)-1-phenyl-2-aminopropane at sigma-receptors. Journal of Medicinal Chemistry. 34: 1855-9. PMID 1648139 DOI: 10.1021/Jm00110A015 |
0.442 |
|
| 1991 |
Glennon RA, Ismaiel AM, Smith JD, Yousif M, El-Ashmawy M, Herndon JL, Fischer JB, Howie KJB, Server AC. Binding of substituted and conformationally restricted derivatives of N-(3-phenyl-n-propyl)-1-phenyl-2-aminopropane at .sigma.-receptors Journal of Medicinal Chemistry. 34: 1855-1859. DOI: 10.1021/JM00110A015 |
0.356 |
|
| 1991 |
Glennon RA, Ismaiel AM, Chaurasia C, Titeler M. 5-HT1D serotonin receptors: Results of a structure-affinity investigation Drug Development Research. 22: 25-36. DOI: 10.1002/Ddr.430220103 |
0.469 |
|
| 1990 |
Glennon RA, Ismaiel AE, McCarthy BG, Peroutka SJ. Binding of arylpiperazines to 5-HT3 serotonin receptors: results of a structure-affinity study. European Journal of Pharmacology. 168: 387-92. PMID 2583244 DOI: 10.1016/0014-2999(89)90802-9 |
0.543 |
|
| 1990 |
Glennon RA, Misenheimer BR. Stimulus effects of N-monoethyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDE) and N-hydroxy-1-(3,4-methylenedioxyphenyl)-2-aminopropane (N-OH MDA) in rats trained to discriminate MDMA from saline. Pharmacology, Biochemistry, and Behavior. 33: 909-12. PMID 2575759 DOI: 10.1016/0091-3057(89)90491-7 |
0.395 |
|
| 1990 |
Seggel MR, Yousif MY, Lyon RA, Titeler M, Roth BL, Suba EA, Glennon RA. A structure-affinity study of the binding of 4-substituted analogues of 1-(2,5-dimethoxyphenyl)-2-aminopropane at 5-HT2 serotonin receptors. Journal of Medicinal Chemistry. 33: 1032-6. PMID 2308135 DOI: 10.1021/Jm00165A023 |
0.593 |
|
| 1990 |
Ismaiel AM, Titeler M, Miller KJ, Smith TS, Glennon RA. 5-HT1 and 5-HT2 binding profiles of the serotonergic agents alpha-methylserotonin and 2-methylserotonin. Journal of Medicinal Chemistry. 33: 755-8. PMID 2299641 DOI: 10.1021/Jm00164A046 |
0.492 |
|
| 1990 |
Glennon RA, Chaurasia C, Titeler M. Binding of indolylalkylamines at 5-HT2 serotonin receptors: examination of a hydrophobic binding region. Journal of Medicinal Chemistry. 33: 2777-84. PMID 2213830 DOI: 10.1021/Jm00172A016 |
0.579 |
|
| 1990 |
Glennon RA. Serotonin receptors: clinical implications. Neuroscience and Biobehavioral Reviews. 14: 35-47. PMID 2183098 DOI: 10.1016/S0149-7634(05)80158-7 |
0.478 |
|
| 1990 |
Darmani NA, Martin BR, Pandey U, Glennon RA. Do functional relationships exist between 5-HT1A and 5-HT2 receptors? Pharmacology, Biochemistry, and Behavior. 36: 901-6. PMID 2145593 DOI: 10.1016/0091-3057(90)90098-3 |
0.511 |
|
| 1990 |
TEITLER M, LEONHARDT S, APPEL NM, DE SOUZA EB, GLENNON RA. Receptor Pharmacology of MDMA and Related Hallucinogens Annals of the New York Academy of Sciences. 600: 626-638. PMID 1979215 DOI: 10.1111/J.1749-6632.1990.Tb16915.X |
0.537 |
|
| 1990 |
Glennon RA, Battaglia G, Smith JD. (-)PPAP: A new and selective ligand for sigma binding sites Pharmacology, Biochemistry and Behavior. 37: 557-559. PMID 1965044 DOI: 10.1016/0091-3057(90)90027-F |
0.438 |
|
| 1990 |
Pierson ME, Lyon RA, Titeler M, Schulman SB, Kowalski P, Glennon RA. Design and synthesis and propranolol analogs as serotonergic agents [Erratum to document cited in CA110(19):172847n] Journal of Medicinal Chemistry. 33: 1270-1270. DOI: 10.1021/Jm00166A029 |
0.309 |
|
| 1990 |
Rydelek-Fitzgerald L, Tietler M, Fletcher PW, Ismaiel AM, Glennon RA. NAN-190: agonist and antagonist interactions with brain 5-HT1A receptors Brain Research. 532: 191-196. DOI: 10.1016/0006-8993(90)91759-A |
0.532 |
|
| 1989 |
Glennon RA, Ismaiel AE, Martin B, Poff D, Sutton M. A preliminary behavioral investigation of PMMA, the 4-methoxy analog of methamphetamine. Pharmacology, Biochemistry, and Behavior. 31: 9-13. PMID 3252264 DOI: 10.1016/0091-3057(88)90303-6 |
0.354 |
|
| 1989 |
Glennon RA, Titeler M, Lyon RA. A preliminary investigation of the psychoactive agent 4-bromo-2,5-dimethoxyphenethylamine: a potential drug of abuse. Pharmacology, Biochemistry, and Behavior. 30: 597-601. PMID 3211969 DOI: 10.1016/0091-3057(88)90071-8 |
0.506 |
|
| 1989 |
Glennon RA, Naiman NA, Pierson ME, Titeler M, Lyon RA, Weisberg E. NAN-190: an arylpiperazine analog that antagonizes the stimulus effects of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). European Journal of Pharmacology. 154: 339-41. PMID 2976673 DOI: 10.1016/0014-2999(88)90212-9 |
0.484 |
|
| 1989 |
Glennon RA, Naiman NA, Pierson ME, Smith JD, Ismaiel AM, Titeler M, Lyon RA. N-(phthalimidoalkyl) derivatives of serotonergic agents: a common interaction at 5-HT1A serotonin binding sites? Journal of Medicinal Chemistry. 32: 1921-6. PMID 2754715 DOI: 10.1021/JM00128A039 |
0.348 |
|
| 1989 |
Pierson ME, Lyon RA, Titeler M, Schulman SB, Kowalski P, Glennon RA. Design and synthesis of propranolol analogues as serotonergic agents. Journal of Medicinal Chemistry. 32: 859-63. PMID 2539480 DOI: 10.1021/Jm00124A021 |
0.451 |
|
| 1989 |
Naiman N, Lyon RA, Bullock AE, Rydelek LT, Titeler M, Glennon RA. 2-(Alkylamino)tetralin derivatives: interaction with 5-HT1A serotonin binding sites. Journal of Medicinal Chemistry. 32: 253-6. PMID 2521252 DOI: 10.1021/Jm00121A045 |
0.503 |
|
| 1989 |
Sadzot B, Baraban JM, Glennon RA, Lyon RA, Leonhardt S, Jan CR, Titeler M. Hallucinogenic drug interactions at human brain 5-HT2 receptors: implications for treating LSD-induced hallucinogenesis. Psychopharmacology. 98: 495-9. PMID 2505289 DOI: 10.1007/Bf00441948 |
0.567 |
|
| 1989 |
Glennon RA, Naiman NA, Pierson ME, Misenheimer B, Herndon JL, Titeler M, Lyon RA. Stimulus properties of arylpiperazines: NAN-190, a potential 5-HT1A serotonin antagonist Drug Development Research. 16: 335-343. DOI: 10.1002/Ddr.430160227 |
0.495 |
|
| 1988 |
Lyon RA, Titeler M, Seggel MR, Glennon RA. Indolealkylamine analogs share 5-HT2 binding characteristics with phenylalkylamine hallucinogens. European Journal of Pharmacology. 145: 291-7. PMID 3350047 DOI: 10.1016/0014-2999(88)90432-3 |
0.55 |
|
| 1988 |
Glennon RA, Seggel MR, Soine WH, Herrick-Davis K, Lyon RA, Titeler M. [125I]-1-(2,5-dimethoxy-4-iodophenyl)-2-amino-propane: an iodinated radioligand that specifically labels the agonist high-affinity state of 5-HT2 serotonin receptors. Journal of Medicinal Chemistry. 31: 5-7. PMID 3336031 DOI: 10.1021/Jm00396A003 |
0.524 |
|
| 1988 |
Glennon RA. Site-selective serotonin agonists as discriminative stimuli. Psychopharmacology Series. 4: 15-31. PMID 3293039 DOI: 10.1007/978-3-642-73223-2_2 |
0.433 |
|
| 1988 |
Glennon RA, Naiman NA, Lyon RA, Titeler M. Arylpiperazine derivatives as high-affinity 5-HT1A serotonin ligands. Journal of Medicinal Chemistry. 31: 1968-71. PMID 3172131 DOI: 10.1021/Jm00118A018 |
0.467 |
|
| 1988 |
Titeler M, Lyon RA, Glennon RA. Radioligand binding evidence implicates the brain 5-HT2 receptor as a site of action for LSD and phenylisopropylamine hallucinogens. Psychopharmacology. 94: 213-6. PMID 3127847 DOI: 10.1007/Bf00176847 |
0.559 |
|
| 1988 |
Glennon RA, Titeler M, Lyon RA, Slusher RM. N,N-di-n-propylserotonin: binding at serotonin binding sites and a comparison with 8-hydroxy-2-(di-n-propylamino)tetralin. Journal of Medicinal Chemistry. 31: 867-70. PMID 2965244 DOI: 10.1021/Jm00399A031 |
0.536 |
|
| 1988 |
Glennon RA, Yousif M, Patrick G. Stimulus properties of 1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDA) analogs. Pharmacology, Biochemistry, and Behavior. 29: 443-9. PMID 2896360 DOI: 10.1016/0091-3057(88)90001-9 |
0.364 |
|
| 1988 |
Glennon RA, Pierson ME, McKenney JD. Stimulus generalization of 1-(3-trifluoromethylphenyl)piperazine (TFMPP) to propranolol, pindolol, and mesulergine. Pharmacology, Biochemistry, and Behavior. 29: 197-9. PMID 2895480 DOI: 10.1016/0091-3057(88)90296-1 |
0.446 |
|
| 1988 |
Young R, Glennon RA. Stimulus properties of benzodiazepines: correlations with binding affinities, therapeutic potency, and structure activity relationships (SAR). Psychopharmacology. 93: 529-33. PMID 2893418 DOI: 10.1007/Bf00207248 |
0.419 |
|
| 1987 |
Titeler M, Lyon RA, Davis KH, Glennon RA. Selectivity of serotonergic drugs for multiple brain serotonin receptors. Role of [3H]-4-bromo-2,5-dimethoxyphenylisopropylamine ([3H]DOB), a 5-HT2 agonist radioligand. Biochemical Pharmacology. 36: 3265-71. PMID 3663239 DOI: 10.1016/0006-2952(87)90643-5 |
0.54 |
|
| 1987 |
Seggel MR, Qureshi GD, Glennon RA. Effect of 5-HT2-selective agonists on cat platelet aggregation. Life Sciences. 41: 1077-81. PMID 3613863 DOI: 10.1016/0024-3205(87)90624-2 |
0.452 |
|
| 1987 |
Glennon RA, Yousif M, Naiman N, Kalix P. Methcathinone: a new and potent amphetamine-like agent. Pharmacology, Biochemistry, and Behavior. 26: 547-51. PMID 3575369 DOI: 10.1016/0091-3057(87)90164-X |
0.394 |
|
| 1987 |
Glennon RA, Titeler M, Seggel MR, Lyon RA. N-methyl derivatives of the 5-HT2 agonist 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. Journal of Medicinal Chemistry. 30: 930-2. PMID 3572981 DOI: 10.1021/Jm00388A032 |
0.544 |
|
| 1987 |
Arvidsson LE, Hacksell U, Glennon RA. Recent advances in central 5-hydroxytryptamine receptor agonists and antagonists. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. Progres Des Recherches Pharmaceutiques. 30: 365-471. PMID 3544048 DOI: 10.1007/978-3-0348-9311-4_11 |
0.501 |
|
| 1987 |
Glennon RA. Central serotonin receptors as targets for drug research. Journal of Medicinal Chemistry. 30: 1-12. PMID 3543362 DOI: 10.1021/Jm00384A001 |
0.376 |
|
| 1987 |
Young R, Glennon RA, Dewey WL. Effects of pyrazolopyridines and a triazolopyridazine on the pentobarbital discriminative stimulus. Psychopharmacology. 93: 494-7. PMID 2893416 DOI: 10.1007/Bf00207241 |
0.365 |
|
| 1987 |
Rosecrans JA, Glennon RA. The effect of MDA and MDMA ("Ecstasy") isomers in combination with pirenpirone on operant responding in mice. Pharmacology, Biochemistry, and Behavior. 28: 39-42. PMID 2889221 DOI: 10.1016/0091-3057(87)90008-6 |
0.418 |
|
| 1987 |
Shehata IA, Glennon RA. Mesoionic isoxazolo[2,3-a]pyrimidinediones and 1,3,4-oxadiazolo[3,2-a]pyrimidinediones as potential adenosine antagonists Journal of Heterocyclic Chemistry. 24: 1291-1295. DOI: 10.1002/Jhet.5570240511 |
0.322 |
|
| 1987 |
GLENNON RA, TITELER M, SEGGEL MR, LYON RA. ChemInform Abstract: N-Methyl Derivatives of the 5-HT2 Agonist 1-(4-Bromo-2,5-dimethoxyphenyl)-2-aminopropane. Cheminform. 18. DOI: 10.1002/CHIN.198746151 |
0.408 |
|
| 1987 |
GLENNON RA, SLUSHER RM, LYON RA, TITELER M, MCKENNEY JD. ChemInform Abstract: 5-HT1 and 5-HT2 Binding Characteristics of Some Quipazine Analogues. Cheminform. 18. DOI: 10.1002/CHIN.198715382 |
0.393 |
|
| 1986 |
Titeler M, Herrick K, Lyon RA, McKenney JD, Glennon RA. [3H]DOB: a specific agonist radioligand for 5-HT2 serotonin receptors. European Journal of Pharmacology. 117: 145-6. PMID 4085543 DOI: 10.1016/0014-2999(85)90486-8 |
0.524 |
|
| 1986 |
Glennon RA, McKenney JD, Lyon RA, Titeler M. 5-HT1 and 5-HT2 binding characteristics of 1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane analogues. Journal of Medicinal Chemistry. 29: 194-9. PMID 3950904 DOI: 10.1002/Chin.198623175 |
0.539 |
|
| 1986 |
McKenney JD, Glennon RA. TFMPP may produce its stimulus effects via a 5-HT1B mechanism. Pharmacology, Biochemistry, and Behavior. 24: 43-7. PMID 3945665 DOI: 10.1016/0091-3057(86)90042-0 |
0.326 |
|
| 1986 |
Rasmussen K, Glennon RA, Aghajanian GK. Phenethylamine hallucinogens in the locus coeruleus: potency of action correlates with rank order of 5-HT2 binding affinity. European Journal of Pharmacology. 132: 79-82. PMID 3816969 DOI: 10.1016/0014-2999(86)90014-2 |
0.548 |
|
| 1986 |
Young R, Rosecrans JA, Glennon RA. Further studies on the dose-dependent stimulus properties of 5-methoxy-N,N-dimethyltryptamine. Pharmacology, Biochemistry, and Behavior. 25: 1207-10. PMID 3809222 DOI: 10.1016/0091-3057(86)90113-9 |
0.47 |
|
| 1986 |
Kalix P, Glennon RA. Further evidence for an amphetamine-like mechanism of action of the alkaloid cathinone. Biochemical Pharmacology. 35: 3015-9. PMID 3753515 DOI: 10.1016/0006-2952(86)90380-1 |
0.355 |
|
| 1986 |
Lyon RA, Titeler M, McKenney JD, Magee PS, Glennon RA. Synthesis and evaluation of phenyl- and benzoylpiperazines as potential serotonergic agents. Journal of Medicinal Chemistry. 29: 630-4. PMID 3701781 DOI: 10.1002/Chin.198638235 |
0.511 |
|
| 1986 |
Glennon RA. Discriminative stimulus properties of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH DPAT). Pharmacology, Biochemistry, and Behavior. 25: 135-9. PMID 2944129 DOI: 10.1016/0091-3057(86)90243-1 |
0.507 |
|
| 1986 |
Glennon RA. Discriminative stimulus properties of the serotonergic agent 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI). Life Sciences. 39: 825-30. PMID 2943960 DOI: 10.1016/0024-3205(86)90461-3 |
0.502 |
|
| 1986 |
Glennon RA, Hauck AE. Mechanistic studies on DOM as a discriminative stimulus. Pharmacology, Biochemistry, and Behavior. 23: 937-41. PMID 2934750 DOI: 10.1016/0091-3057(85)90096-6 |
0.462 |
|
| 1986 |
Glennon RA. Discriminative stimulus properties of phenylisopropylamine derivatives. Drug and Alcohol Dependence. 17: 119-34. PMID 2874967 DOI: 10.1016/0376-8716(86)90003-7 |
0.35 |
|
| 1986 |
Lyon RA, Glennon RA, Titeler M. 3,4-Methylenedioxymethamphetamine (MDMA): stereoselective interactions at brain 5-HT1 and 5-HT2 receptors. Psychopharmacology. 88: 525-6. PMID 2871581 DOI: 10.1007/Bf00178519 |
0.513 |
|
| 1986 |
Glennon RA, Slusher RM, Lyon RA, Titeler M, McKenney JD. 5-HT1 and 5-HT2: binding characteristics of some quipazine analogs Journal of Medicinal Chemistry. 29: 2375-2380. DOI: 10.1021/Jm00161A038 |
0.524 |
|
| 1986 |
GLENNON RA, MCKENNEY JD, LYON RA, TITELER M. ChemInform Abstract: 5-HT1 and 5-HT2 Binding Characteristics of 1-(2,5-Dimethoxy-4-bromophenyl)-2-aminopropane Analogues. Chemischer Informationsdienst. 17. DOI: 10.1002/CHIN.198623175 |
0.394 |
|
| 1985 |
Glennon RA, Young R, Hauck AE, McKenney JD. Structure-activity studies on amphetamine analogs using drug discrimination methodology. Pharmacology, Biochemistry, and Behavior. 21: 895-901. PMID 6522418 DOI: 10.1016/S0091-3057(84)80071-4 |
0.341 |
|
| 1985 |
Glennon RA, Titeler M, McKenney JD. Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents. Life Sciences. 35: 2505-11. PMID 6513725 DOI: 10.1016/0024-3205(84)90436-3 |
0.512 |
|
| 1985 |
Glennon RA, Young R, Hauck AE. Structure-activity studies on methoxy-substituted phenylisopropylamines using drug discrimination methodology. Pharmacology, Biochemistry, and Behavior. 22: 723-9. PMID 3839309 DOI: 10.1016/0091-3057(85)90520-9 |
0.325 |
|
| 1984 |
Glennon RA, Jacyno JM, Young R, McKenney JD, Nelson D. Synthesis and evaluation of a novel series of N,N-dimethylisotryptamines. Journal of Medicinal Chemistry. 27: 41-5. PMID 6581313 DOI: 10.1002/Chin.198424187 |
0.495 |
|
| 1984 |
Glennon RA, McKenney JD, Young R. Discriminative stimulus properties of the serotonin agonist 1-(3-trifluoromethylphenyl)piperazine (TFMPP). Life Sciences. 35: 1475-80. PMID 6482668 DOI: 10.1016/0024-3205(84)90164-4 |
0.472 |
|
| 1984 |
Shannon M, Battaglia G, Glennon RA, Titeler M. 5-HT1 and 5-HT2 binding properties of derivatives of the hallucinugen 1-(2,5-dimethoxyphenyl)-2-aminopropane (2,5-DMA) European Journal of Pharmacology. 102: 23-29. PMID 6479216 DOI: 10.1016/0014-2999(84)90333-9 |
0.532 |
|
| 1984 |
Glennon RA, Schechter MD, Rosecrans JA. Discriminative stimulus properties of S(-)- and R(+)-cathinone, (+)-cathine and several structural modifications. Pharmacology, Biochemistry, and Behavior. 21: 1-3. PMID 6463083 DOI: 10.1016/0091-3057(84)90121-7 |
0.302 |
|
| 1984 |
Young R, Glennon RA, Dewey WL. Stereoselective stimulus effects of 3-methylflunitrazepam and pentobarbital. Life Sciences. 34: 1977-83. PMID 6328149 DOI: 10.1016/0024-3205(84)90129-2 |
0.35 |
|
| 1984 |
Glennon RA, Young R, Soine W. 1-(2,3-Methylenedioxyphenyl)-2-aminopropane (2,3-MDA): a preliminary investigation. General Pharmacology. 15: 361-2. PMID 6149169 DOI: 10.1016/0306-3623(84)90016-8 |
0.304 |
|
| 1984 |
Glennon RA, Tejani-Butt SM, Padgett W, Daly JW. Mesoionic xanthine analogues: antagonists of adenosine receptors. Journal of Medicinal Chemistry. 27: 1364-7. PMID 6090665 DOI: 10.1002/Chin.198509254 |
0.401 |
|
| 1983 |
Glennon RA, Young R, Benington F, Morin RD. Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane. Journal of Medicinal Chemistry. 25: 1163-8. PMID 7143352 DOI: 10.1002/Chin.198310183 |
0.549 |
|
| 1983 |
Kline TB, Benington F, Morin RD, Beaton JM, Glennon RA, Domelsmith LN, Houk KN, Rozeboom MD. Structure-activity relationships for hallucinogenic N,N-dialkyltryptamines: photoelectron spectra and serotonin receptor affinities of methylthio and methylenedioxy derivatives. Journal of Medicinal Chemistry. 25: 1381-3. PMID 6815326 DOI: 10.1021/jm00353a021 |
0.401 |
|
| 1983 |
Glennon RA, Young R, Rosecrans JA. Antagonism of the effects of the hallucinogen DOM and the purported 5-HT agonist quipazine by 5-HT2 antagonists. European Journal of Pharmacology. 91: 189-96. PMID 6617740 DOI: 10.1016/0014-2999(83)90464-8 |
0.538 |
|
| 1983 |
Glennon RA, Young R, Jacyno JM. Indolealkylamine and phenalkylamine hallucinogens. Effect of alpha-methyl and N-methyl substituents on behavioral activity. Biochemical Pharmacology. 32: 1267-73. PMID 6573879 DOI: 10.1016/0006-2952(83)90281-2 |
0.302 |
|
| 1983 |
Glennon RA, Young R, Jacyno JM, Slusher M, Rosecrans JA. DOM-stimulus generalization to LSD and other hallucinogenic indolealkylamines. European Journal of Pharmacology. 86: 453-9. PMID 6572591 DOI: 10.1016/0014-2999(83)90196-6 |
0.359 |
|
| 1983 |
Young R, Rosecrans JA, Glennon RA. Behavioral effects of 5-methoxy-N,N-dimethyltryptamine and dose-dependent antagonism by BC-105. Psychopharmacology. 80: 156-60. PMID 6410445 DOI: 10.1007/Bf00427960 |
0.328 |
|
| 1983 |
GLENNON RA, YOUNG R, BENINGTON F, MORIN RD. ChemInform Abstract: BEHAVIORAL AND SEROTONIN RECEPTOR PROPERTIES OF 4-SUBSTITUTED DERIVATIVES OF THE HALLUCINOGEN 1-(2,5-DIMETHOXYPHENYL)-2-AMINOPROPANE Chemischer Informationsdienst. 14. DOI: 10.1002/CHIN.198310183 |
0.315 |
|
| 1982 |
Domelsmith LN, Eaton TA, Houk KN, Anderson GM, Glennon RA, Shulgin AT, Castagnoli N, Kollman PA. Photoelectron spectra of psychotropic drugs. 6. Relationships between the physical properties and pharmacological actions of amphetamine analogues. Journal of Medicinal Chemistry. 24: 1414-21. PMID 7310818 DOI: 10.1021/Jm00144A009 |
0.336 |
|
| 1982 |
Glennon RA. Serotonin receptor interactions of harmaline and several related beta-carbolines. Life Sciences. 29: 861-5. PMID 7300579 DOI: 10.1016/0024-3205(81)90043-6 |
0.493 |
|
| 1982 |
Young R, Rosecrans JA, Glennon RA. Comparative discriminative stimulus effects of 5-methoxy-N,N-dimethyltryptamine and LSD. Life Sciences. 30: 2057-62. PMID 7109835 DOI: 10.1016/0024-3205(82)90446-5 |
0.369 |
|
| 1982 |
Glennon RA, Jacyno JM, Salley JJ. 2,3-dihydro and carbocyclic analogues of tryptamines: interaction with serotonin receptors. Journal of Medicinal Chemistry. 25: 68-70. PMID 7086824 DOI: 10.1002/Chin.198228188 |
0.455 |
|
| 1982 |
Glennon RA, Young R, Rosecrans JA. A comparison of the behavioral effects of DOM homologs. Pharmacology, Biochemistry, and Behavior. 16: 557-9. PMID 7071089 DOI: 10.1016/0091-3057(82)90414-2 |
0.337 |
|
| 1982 |
Glennon RA, Young R, Rosecrans JA. Discriminative stimulus properties of DOM and several molecular modifications. Pharmacology, Biochemistry, and Behavior. 16: 553-6. PMID 7071088 DOI: 10.1016/0091-3057(82)90413-0 |
0.315 |
|
| 1982 |
Glennon RA, Liebowitz SM. Serotonin receptor affinity of cathinone and related analogues. Journal of Medicinal Chemistry. 25: 393-7. PMID 7069716 DOI: 10.1021/Jm00346A012 |
0.49 |
|
| 1982 |
Glennon RA, Young R, Benington F, Morin RD. Hallucinogens as discriminative stimuli: a comparison of 4-OMe DMT and 5-OMe DMT with their methythio counterparts. Life Sciences. 30: 465-7. PMID 6801410 DOI: 10.1016/0024-3205(82)90463-5 |
0.355 |
|
| 1982 |
Glennon RA, Rosecrans JA. Indolealkylamine and phenalkylamine hallucinogens: a brief overview. Neuroscience and Biobehavioral Reviews. 6: 489-97. PMID 6757811 DOI: 10.1016/0149-7634(82)90030-6 |
0.353 |
|
| 1982 |
Rogers ME, Glennon RA, Smith JD, Boots MR, Nanavati N, Maconaughey E, Aub D, Thomas S, Bass RG, Mbagwu G. Mesoionic purinone analogues as inhibitors of cyclic-AMP phosphodiesterase: a comparison of several ring systems. Journal of Medicinal Chemistry. 24: 1284-7. PMID 6273558 DOI: 10.1002/Chin.198216240 |
0.326 |
|
| 1982 |
Glennon RA, Young R. Comparison of behavioral properties of di- and tri-methoxyphenylisopropylamines Pharmacology Biochemistry and Behavior. 17: 603-607. DOI: 10.1016/0091-3057(82)90330-6 |
0.313 |
|
| 1982 |
GLENNON RA, LIEBOWITZ SM. ChemInform Abstract: SEROTONIN RECEPTOR AFFINITY OF CATHINONE AND RELATED ANALOGS Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198240188 |
0.406 |
|
| 1982 |
GLENNON RA, JACYNO JM, SALLEY JJJ. ChemInform Abstract: 2,3-DIHYDRO AND CARBOCYCLIC ANALOGS OF TRYPTAMINES: INTERACTION WITH SEROTONIN RECEPTORS Chemischer Informationsdienst. 13. DOI: 10.1002/CHIN.198228188 |
0.342 |
|
| 1981 |
Glennon RA, Rosecrans JA, Young R. Behavioral properties of psychoactive phenylisopropylamines in rats. European Journal of Pharmacology. 76: 353-60. PMID 7327208 DOI: 10.1016/0014-2999(81)90106-0 |
0.362 |
|
| 1981 |
Glennon RA, Salley JJ, Steinsland OS, Nelson S. Synthesis and evaluation of novel alkylpiperazines as potential dopamine antagonists. Journal of Medicinal Chemistry. 24: 678-83. PMID 7252977 DOI: 10.1002/Chin.198144219 |
0.383 |
|
| 1981 |
Glennon RA, Doot DL, Young R. DOM and related 2,5-dimethoxy-4-alkylphenylisopropylamines: behavioral and serotonin receptor properties. Pharmacology, Biochemistry, and Behavior. 14: 287-92. PMID 7232455 DOI: 10.1016/0091-3057(81)90392-0 |
0.514 |
|
| 1981 |
GLENNON RA, LIEBOWITZ SM, LEMING-DOOT D, ROSECRANS JA. ChemInform Abstract: DEMETHYL ANALOGS OF PSYCHOACTIVE METHOXYPHENALKYLAMINES: SYNTHESIS AND SEROTONIN RECEPTOR AFFINITIES Chemischer Informationsdienst. 12. DOI: 10.1002/CHIN.198109191 |
0.406 |
|
| 1980 |
Glennon RA, Liebowitz SM, Leming-Doot D, Rosecrans JA. Demethyl analogues of psychoactive methoxyphenalkylamines: synthesis and serotonin receptor affinities. Journal of Medicinal Chemistry. 23: 990-4. PMID 7411554 DOI: 10.1002/Chin.198109191 |
0.494 |
|
| 1980 |
Glennon RA, Liebowitz SM, Anderson GM. Serotonin receptor affinities of psychoactive phenalkylamine analogues. Journal of Medicinal Chemistry. 23: 294-299. PMID 7365744 DOI: 10.1021/Jm00177A017 |
0.575 |
|
| 1980 |
Glennon RA, Schubert E, Jacyno JM, Rosecrans JA. Studies on several 7-substituted N,N-dimethyltryptamines. Journal of Medicinal Chemistry. 23: 1222-6. PMID 6779006 DOI: 10.1002/Chin.198113231 |
0.476 |
|
| 1980 |
Glennon RA, Young R, Rosecrans JA, Kallman MJ. Hallucinogenic agents as discriminative stimuli: a correlation with serotonin receptor affinities. Psychopharmacology. 68: 155-8. PMID 6776558 DOI: 10.1007/Bf00432133 |
0.5 |
|
| 1980 |
GLENNON RA, LIEBOWITZ SM, ANDERSON GMI. ChemInform Abstract: SEROTONIN RECEPTOR AFFINITIES OF PSYCHOACTIVE PHENALKYLAMINE ANALOGS Chemischer Informationsdienst. 11. DOI: 10.1002/Chin.198033163 |
0.516 |
|
| 1979 |
Glennon RA, Gessner PK, Godse DD, Kline BJ. Bufotenine esters Journal of Medicinal Chemistry. 22: 1414-1416. PMID 533890 DOI: 10.1021/jm00197a025 |
0.315 |
|
| 1979 |
Glennon RA. The effect of chirality on serotonin receptor affinity. Life Sciences. 24: 1487-92. PMID 470548 DOI: 10.1016/0024-3205(79)90032-8 |
0.532 |
|
| 1979 |
Glennon RA, Gessner PK. Serotonin receptor binding affinities of tryptamine analogues Journal of Medicinal Chemistry. 22: 428-432. PMID 430481 DOI: 10.1021/Jm00190A014 |
0.54 |
|
| 1979 |
Glennon RA, Rosecrans JA, Young R, Gaines J. Hallucinogens as a discriminative stimuli: generalization of DOM to a 5-methoxy-N, N-dimethyltryptamine stimulus. Life Sciences. 24: 993-7. PMID 286864 DOI: 10.1016/0024-3205(79)90317-5 |
0.551 |
|
| 1979 |
GLENNON RA, GESSNER PK. ChemInform Abstract: SEROTONIN RECEPTOR BINDING AFFINITIES OF TRYPTAMINE ANALOGS Chemischer Informationsdienst. 10. DOI: 10.1002/CHIN.197934211 |
0.402 |
|
| 1978 |
Kier LB, Glennon RA. Psychotomimetic phenalkylamines as serotonin agonists: an SAR analysis. Life Sciences. 22: 1589-93. PMID 672414 DOI: 10.1016/0024-3205(78)90053-X |
0.414 |
|
| 1978 |
Glennon RA, Liebowitz SM, Mack EC. Serotonin receptor binding affinities of several hallucinogenic phenylalkylamine and N,N-dimethyltryptamine analogues. Journal of Medicinal Chemistry. 21: 822-5. PMID 278843 DOI: 10.1002/Chin.197852167 |
0.562 |
|
| 1978 |
GLENNON RA, LIEBOWITZ SM, MACK EC. ChemInform Abstract: SEROTONIN RECEPTOR BINDING AFFINITIES OF SEVERAL HALLUCINOGENIC PHENYLALKYLAMINE AND N,N-DIMETHYLTRYPTAMINE ANALOGS Chemischer Informationsdienst. 9. DOI: 10.1002/CHIN.197852167 |
0.406 |
|
| 1975 |
COBURN RA, GLENNON RA, CHMIELEWICZ ZF. ChemInform Abstract: MESOIONIC PURINONE ANALOGS PART 7, IN VITRO ANTIBACTERIAL ACTIVITY OF MESOIONIC 1,3,4-THIADIAZOLO(3,2-ALPHA)PYRIMIDINE-5,7-DIONES Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197501290 |
0.568 |
|
| 1974 |
Coburn RA, Glennon RA, Chmielewicz ZF. Mesoionic purinone analogs. 7. In vitro antibacterial activity of mesoionic1,3,4-thiadiazolo[3,2-a]pyrimidme-5,7-diones Journal of Medicinal Chemistry. 17: 1025-1027. PMID 4213245 DOI: 10.1021/Jm00255A029 |
0.575 |
|
| 1973 |
Coburn RA, Glennon RA. Mesoionic purinone analogs. IV: Synthesis and in vitro antibacterial properties of mesoionic thiazolo[3,2 α]pyrimidin 5,7 diones and mesoionic 1,3,4 thiadiazolo[3,2 α]pyrimidin 5,7 diones Journal of Pharmaceutical Sciences. 62: 1785-1789. PMID 4202220 DOI: 10.1002/Jps.2600621110 |
0.553 |
|
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