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Minoru Isobe - Publications

Affiliations: 
Agriculture Nagoya University, Nagoya-shi, Aichi-ken, Japan 
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Year Citation  Score
2017 Chuang HY, Isobe M. Synthesis of Rings DEF of Solanoeclepin A. The Journal of Organic Chemistry. PMID 28117589 DOI: 10.1021/Acs.Joc.6B02886  0.413
2017 Chuang H, Isobe M. Synthetic study of solanoeclepin A: Cyclobutane cyclization via SmI2-additive-mediated reaction and D ring functionalization Tetrahedron. 73: 2705-2714. DOI: 10.1016/J.Tet.2017.03.065  0.367
2016 Huang KH, Huang CC, Isobe M. Multicomonent Strategy for the Synthesis of Prostaglandin E2 Methyl Ester under Anion Relay Chelation Control. The Journal of Organic Chemistry. PMID 26811990 DOI: 10.1021/Acs.Joc.5B02735  0.38
2015 Isobe M, Chang WC, Tsou PK, Ploysuk C, Yu CH. Stereochemical Course of Wittig Rearrangements of Dihydropyran Allyl Propargyl Ethers. The Journal of Organic Chemistry. 80: 6222-37. PMID 25992883 DOI: 10.1021/Acs.Joc.5B00678  0.347
2015 Adachi M, Nakajima M, Isobe M. Asymmetric synthesis of 3-azide-4-fluoro-l-phenylalanine. Bioscience, Biotechnology, and Biochemistry. 79: 707-9. PMID 25559241 DOI: 10.1080/09168451.2014.997185  0.331
2014 Lin YT, Lin FY, Isobe M. Novel synthesis of the ABC rings of solanoeclepin A. Organic Letters. 16: 5948-51. PMID 25376022 DOI: 10.1021/Ol5029755  0.413
2014 Chuang HY, Isobe M. Novel synthesis of right segment of solanoeclepin A. Organic Letters. 16: 4166-9. PMID 25058474 DOI: 10.1021/Ol501858W  0.386
2014 Satake Y, Adachi M, Tokoro S, Yotsu-Yamashita M, Isobe M, Nishikawa T. Synthesis of 5- and 8-deoxytetrodotoxin. Chemistry, An Asian Journal. 9: 1922-32. PMID 24861489 DOI: 10.1002/Asia.201402202  0.356
2014 Adachi M, Sakakibara R, Satake Y, Isobe M, Nishikawa T. Synthesis of 5,6,11-Trideoxytetrodotoxin Chemistry Letters. 43: 1719-1721. DOI: 10.1246/Cl.140684  0.407
2014 Chang W, Isobe M. Diastereoselective cobalt-assisted Ferrier-type rearrangement to construct chiral alkynyl cyclohexanones Tetrahedron. 70: 8324-8333. DOI: 10.1016/J.Tet.2014.09.010  0.353
2013 Yamada H, Adachi M, Isobe M, Nishikawa T. Stereocontrolled total synthesis of polygalolide A. Chemistry, An Asian Journal. 8: 1428-35. PMID 23670825 DOI: 10.1002/Asia.201300362  0.423
2013 Nishikawa T, Isobe M. Synthesis of tetrodotoxin, a classic but still fascinating natural product. Chemical Record (New York, N.Y.). 13: 286-302. PMID 23661608 DOI: 10.1002/Tcr.201200025  0.328
2013 Adachi M, Imazu T, Isobe M, Nishikawa T. An improved synthesis of (-)-5,11-dideoxytetrodotoxin. The Journal of Organic Chemistry. 78: 1699-705. PMID 23323757 DOI: 10.1021/Jo302773F  0.395
2013 Isobe M. Conjugate addition approach for natural product synthesis inspired by gibberellin and solanoeclepin A targets Pure and Applied Chemistry. 85: 1149-1160. DOI: 10.1351/Pac-Con-12-10-07  0.386
2012 Tsao KW, Cheng CY, Isobe M. Cobalt-mediated synthesis of the tricyclo[5.2.1.0(1,6)]decene framework in solanoeclepin A. Organic Letters. 14: 5274-7. PMID 23020121 DOI: 10.1021/Ol302432D  0.363
2012 Chou CM, Tung YW, Lin MI, Chan D, Phakhodee W, Isobe M. Chemical synthesis of coelenterazine and its analogs: New route by four segment-couplings Heterocycles. 86: 1323-1339. DOI: 10.3987/Com-12-S(N)85  0.379
2012 Matsumoto N, Tsujimoto T, Nakazaki A, Isobe M, Nishikawa T. Synthetic studies on pactamycin, a potent antitumor antibiotic Rsc Advances. 2: 9448-9462. DOI: 10.1039/C2Ra21060F  0.372
2012 Isobe M, Chiang C, Tsao K, Cheng C, Bruening R. Stereocontrol with Lithium Trimethylzincate toward Gibberellin Synthesis (Eur. J. Org. Chem. 11/2012) European Journal of Organic Chemistry. 2012: n/a-n/a. DOI: 10.1002/Ejoc.201290024  0.617
2012 Isobe M, Chiang CT, Tsao KW, Cheng CY, Bruening R. Stereocontrol with lithium trimethylzincate toward gibberellin synthesis European Journal of Organic Chemistry. 2109-2113. DOI: 10.1002/Ejoc.201200156  0.644
2011 Adachi M, Yamada H, Isobe M, Nishikawa T. Total synthesis of polygalolide A. Organic Letters. 13: 6532-5. PMID 22092027 DOI: 10.1021/Ol2028256  0.392
2011 Sugino K, Nakazaki A, Isobe M, Nishikawa T. Synthetic study on sespendole, an indole sesquiterpene alkaloid: Stereo-controlled synthesis of the sesquiterpene segment bearing all requisite stereogenic centers Synlett. 647-650. DOI: 10.1055/S-0030-1259551  0.393
2011 Isobe M, Niyomchon S, Cheng C, Hasakunpaisarn A. Synthesis of bicyclo[4.2.0]octan-2-ol, a substructure of solanoeclepin A Tetrahedron Letters. 52: 1847-1850. DOI: 10.1016/J.Tetlet.2011.01.152  0.394
2011 Cheng C, Isobe M. Three types of products by carbon nucleophiles toward methoxyphenylacetylenic sulfones Tetrahedron. 67: 9957-9965. DOI: 10.1016/J.Tet.2011.09.078  0.319
2011 Phakhodee W, Toyoda M, Chou CM, Khunnawutmanotham N, Isobe M. Suzuki-Miyaura coupling for general synthesis of dehydrocoelenterazine applicable for 6-position analogs directing toward bioluminescence studies Tetrahedron. 67: 1150-1157. DOI: 10.1016/J.Tet.2010.12.001  0.402
2011 Isaji H, Nakazaki A, Isobe M, Nishikawa T. Concise Synthesis of Deformylflustrabromine, a Marine Indole Alkaloid, through a 2-Propynyl Dicobalt Hexacarbonyl Complex Chemistry Letters. 40: 1079-1081. DOI: 10.1002/Chin.201212200  0.426
2010 Tsao KW, Isobe M. Chiral cyclobutane synthesis by exploiting a heteroatom-directed conjugate addition. Organic Letters. 12: 5338-41. PMID 21028786 DOI: 10.1021/Ol102383G  0.393
2010 Isobe M, Hamajima A. Ciguatoxin: developing the methodology for total synthesis. Natural Product Reports. 27: 1204-26. PMID 20589300 DOI: 10.1039/B919467N  0.331
2010 Nishiyama T, Kusumoto Y, Okumura K, Hara K, Kusaba S, Hirata K, Kamiya Y, Isobe M, Nakano K, Kotsuki H, Ichikawa Y. Synthesis of glycocinnasperimicin D. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 600-10. PMID 19937620 DOI: 10.1002/Chem.200901745  0.403
2010 Nishikawa T, Koide Y, Adachi M, Isobe M. Synthesis of an Advanced Intermediate Bearing Two Hydroxy Groups for (-)-Tetrodotoxin and Its Analogs Bulletin of the Chemical Society of Japan. 83: 66-68. DOI: 10.1246/Bcsj.20090223  0.395
2010 Satake Y, Nishikawa T, Hiramatsu T, Araki H, Isobe M. Scalable Synthesis of a NewDihydroxylated Intermediate for Tetrodotoxin and Its Analogues Synthesis. 2010: 1992-1998. DOI: 10.1055/S-0029-1218747  0.419
2010 Sydnes MO, Miyazaki A, Isobe M, Ohinata H, Miyazu M, Takai A. Development of a new protein labeling strategy, oxidation labeling. part 1: Preliminary evaluation and synthesis of tautomycin containing a metal coordinating unit Tetrahedron. 66: 1735-1741. DOI: 10.1016/J.Tet.2009.12.036  0.3
2010 Huang G, Isobe M. ChemInform Abstract: Stereoselective Synthesis of Sugar Allenes and Their Hydrosilylation Catalyzed by Biscobaltoctacarbonyl. Cheminform. 33: no-no. DOI: 10.1002/CHIN.200218164  0.311
2010 ICHIKAWA Y, KOBAYASHI C, ISOBE M. ChemInform Abstract: Synthesis of Nitrogen-Containing Unsaturated Carbohydrates via an Allyl Cyanate-to-Isocyanate Rearrangement. Cheminform. 27: no-no. DOI: 10.1002/CHIN.199623235  0.307
2009 Hamajima A, Isobe M. Total synthesis of ciguatoxin. Angewandte Chemie (International Ed. in English). 48: 2941-5. PMID 19294712 DOI: 10.1002/Anie.200805996  0.375
2009 Nishikawa T, Urabe D, Isobe M. Syntheses Of N-Acylisoxazolidine Derivatives, Related To A Partial Structure Found In Zetekitoxin Ab, A Golden Frog Poison Heterocycles. 79: 379-385. DOI: 10.3987/Com-08-S(D)44  0.312
2009 Makarasen A, Kuse M, Nishikawa T, Isobe M. Substituent Effect of Imino-O-arenesulfonates, a Coupling Partner in Suzuki-Miyaura Reaction for Substitution of the Pyrazine Ring : A Study for the Synthesis of Coelenterazine Analogs Bulletin of the Chemical Society of Japan. 82: 870-878. DOI: 10.1246/Bcsj.82.870  0.392
2009 Hamajima A, Isobe M. Synthesis of Ciguatoxin Synfacts. 2009: 941-941. DOI: 10.1055/S-0029-1217612  0.396
2009 Makarasen A, Nishikawa T, Isobe M. Synthesis of Four Lysine-LinkedCereulide Analogues Showing Ionophoric Activity Towards PotassiumCations as Lead Compounds for Emetic Toxin-Detection by Immunoassays Synthesis. 2009: 2184-2204. DOI: 10.1055/S-0029-1216837  0.36
2009 Adachi M, Yamauchi E, Komada T, Isobe M. Novel stereocontrolled synthesis of highly functionalized cyclobutanes by epoxide opening through a carbanion intermediate in heteroconjugate addition Synlett. 1157-1161. DOI: 10.1055/S-0028-1088108  0.389
2008 Sugino K, Yoshimura H, Nishikawa T, Isobe M. Regioselectivity of Larock indole synthesis using functionalized alkynes. Bioscience, Biotechnology, and Biochemistry. 72: 2092-102. PMID 18685222 DOI: 10.1271/Bbb.80179  0.394
2008 Kajii S, Nishikawa T, Isobe M. Synthetic studies and biosynthetic speculation on marine alkaloid chartelline. Chemical Communications (Cambridge, England). 3121-3. PMID 18594715 DOI: 10.1039/B803797C  0.352
2008 Sydnes MO, Isobe M. One-pot reductive monoalkylation of nitro aryls with hydrogen over Pd/C Tetrahedron Letters. 49: 1199-1202. DOI: 10.1016/J.Tetlet.2007.12.030  0.335
2008 Kajii S, Nishikawa T, Isobe M. Synthesis of N-hydroxyenamide, a potential precursor of chartelline Tetrahedron Letters. 49: 594-597. DOI: 10.1016/J.Tetlet.2007.11.155  0.32
2008 Sydnes MO, Kuse M, Isobe M. Reductive monoalkylation of nitro aryls in one-pot Tetrahedron. 64: 6406-6414. DOI: 10.1016/J.Tet.2008.04.077  0.351
2007 Isobe M, Kurono M, Tsuboi K, Takai A. Synthesis of [18,19,21,22-(13)C4]-labeled tautomycin as an NMR probe of protein phosphatase inhibitor. Chemistry, An Asian Journal. 2: 377-85. PMID 17441173 DOI: 10.1002/Asia.200600387  0.3
2007 Suntornchashwej S, Suwanborirux K, Koga K, Isobe M. Malyngamide X: the first (7R)-lyngbic acid that connects to a new tripeptide backbone from the Thai sea hare Bursatella leachii. Chemistry, An Asian Journal. 2: 114-22. PMID 17441144 DOI: 10.1002/Asia.200600219  0.319
2007 Nonoyama A, Hamajima A, Isobe M. Synthesis of symmetric HIJ-ring model of ciguatoxin Tetrahedron. 63: 5886-5894. DOI: 10.1016/J.Tet.2007.03.012  0.402
2007 Sydnes MO, Isobe M. Synthesis of the second generation photoaffinity probes of tautomycin Tetrahedron. 63: 2593-2603. DOI: 10.1016/J.Tet.2007.01.047  0.32
2007 Suntornchashwej S, Suwanborirux K, Isobe M. Total synthesis of malyngamide X and its 7′S-epi isomer Tetrahedron. 63: 3217-3226. DOI: 10.1016/J.Tet.2007.01.035  0.39
2006 Ichikawa Y, Matsukawa Y, Tamura M, Ohara F, Isobe M, Kotsuki H. Synthesis of urea-tethered disaccharides in water. Chemistry, An Asian Journal. 1: 717-23. PMID 17441114 DOI: 10.1002/Asia.200600190  0.356
2006 Urabe D, Nishikawa T, Isobe M. An efficient total synthesis of optically active tetrodotoxin from levoglucosenone. Chemistry, An Asian Journal. 1: 125-35. PMID 17441047 DOI: 10.1002/Asia.200600038  0.414
2006 Sawayama Y, Tsujimoto T, Sugino K, Nishikawa T, Isobe M, Kawagishi H. Syntheses of naturally occurring terphenyls and related compounds. Bioscience, Biotechnology, and Biochemistry. 70: 2998-3003. PMID 17151478 DOI: 10.1271/Bbb.60389  0.339
2006 Kanokmedhakul S, Kanokmedhakul K, Nasomjai P, Louangsysouphanh S, Soytong K, Isobe M, Kongsaeree P, Prabpai S, Suksamrarn A. Antifungal azaphilones from the fungus Chaetomium cupreum CC3003. Journal of Natural Products. 69: 891-5. PMID 16792406 DOI: 10.1021/Np060051V  0.3
2006 Nishikawa T, Koide Y, Kanakubo A, Yoshimura H, Isobe M. Synthesis of beta-analogues of C-mannosyltryptophan, a novel C-glycosylamino acid found in proteins. Organic & Biomolecular Chemistry. 4: 1268-77. PMID 16557315 DOI: 10.1039/B516282C  0.303
2006 Ichikawa Y, Matsukawa Y, Isobe M. Synthesis of urea-tethered neoglycoconjugates and pseudooligosaccharides in water. Journal of the American Chemical Society. 128: 3934-8. PMID 16551100 DOI: 10.1021/Ja056253F  0.356
2006 Hamajima A, Isobe M. Convergent synthesis of the right-hand segment of ciguatoxin. Organic Letters. 8: 1205-8. PMID 16524304 DOI: 10.1021/Ol0600741  0.379
2006 Saeeng R, Isobe M. Stereoselective C-Alkynylation, Allenylation, and Prop-2-ynylation Leading to Sugar Glycosides Chemistry Letters. 35: 552-557. DOI: 10.1246/Cl.2006.552  0.367
2006 Nishiyama T, Isobe M, Ichikawa Y. Synthesis of Glycocinnaspermicin D Synfacts. 2006: 4-4. DOI: 10.1055/S-2005-921660  0.307
2005 Matsukawa Y, Isobe M, Kotsuki H, Ichikawa Y. Synthesis of (+)-conagenin. The Journal of Organic Chemistry. 70: 5339-41. PMID 15960545 DOI: 10.1021/Jo050407S  0.389
2005 Ichikawa Y, Yamauchi E, Isobe M. Allyl cyanate-to-isocyanate rearrangement for the synthesis of quaternary stereocenter with nitrogen substituent. Bioscience, Biotechnology, and Biochemistry. 69: 939-43. PMID 15914913 DOI: 10.1271/Bbb.69.939  0.385
2005 Saeeng R, Isobe M. Synthesis of silylallene glycosides and diene diglycosides by C-glycosidation of D-glucal with 1,4-bis(trimethylsilyl)-2-butyne. Organic Letters. 7: 1585-8. PMID 15816758 DOI: 10.1021/Ol050265O  0.411
2005 Nishikawa T, Koide Y, Kajii S, Wada K, Ishikawa M, Isobe M. Stereocontrolled syntheses of alpha-C-mannosyltryptophan and its analogues. Organic & Biomolecular Chemistry. 3: 687-700. PMID 15703809 DOI: 10.1039/B414905J  0.362
2005 Ichikawa Y, Ito T, Isobe M. Stereoselective allyl amine synthesis through enantioselective addition of diethylzinc and [1,3]-chirality transfer: synthesis of lentiginosine and polyoxamic acid derivative. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 1949-57. PMID 15672433 DOI: 10.1002/Chem.200400830  0.407
2005 Isobe M, Kondo N, Kuse M, Mutarapat T, Thasana N. Novel synthetic route of coelenterazines -2- : Synthesis of various dehydrocoelenterazine analogs Heterocycles. 65: 843-856. DOI: 10.3987/Com-05-10351  0.423
2005 Tojo S, Isobe M. Stereocontrolled Synthesis of the Oxabicyclo[2.2.1]heptane Segment of Solanoeclepin A Synthesis. 2005: 1237-1244. DOI: 10.1055/S-2005-865291  0.354
2005 Tsujimoto T, Nishikawa T, Urabe D, Isobe M. Synthesis of Functionalized Cyclopentane for Pactamycin, a Potent Antitumor Antibiotic Synlett. 2005: 433-436. DOI: 10.1055/S-2004-837223  0.35
2004 Ichikawa Y, Hirata K, Ohbayashi M, Isobe M. Total synthesis of (+)-blasticidin s. Chemistry (Weinheim An Der Bergstrasse, Germany). 10: 3241-51. PMID 15224333 DOI: 10.1002/Chem.200305358  0.415
2004 Nishikawa T, Urabe D, Yoshida K, Iwabuchi T, Asai M, Isobe M. Stereocontrolled synthesis of 8,11-dideoxytetrodotoxin, an unnatural analogue of puffer fish toxin. Chemistry (Weinheim An Der Bergstrasse, Germany). 10: 452-62. PMID 14735514 DOI: 10.1002/Chem.200305111  0.42
2004 Nishikawa T, Kajii S, Isobe M. Synthesis of Model Compound Containing an Indole Spiro-β-lactam Moiety with Vinylchloride in Chartellines Chemistry Letters. 33: 440-441. DOI: 10.1246/Cl.2004.440  0.326
2004 Nishikawa T, Kajii S, Isobe M. Novel Synthesis of Bromoindolenine with Spiro-β-lactam in Chartelline Synlett. 2004: 2025-2027. DOI: 10.1055/S-2004-830885  0.351
2004 Ichikawa Y, Matsukawa Y, Isobe M. Urea Glycoside Synthesis in Water Synlett. 2004: 1019-1022. DOI: 10.1055/S-2004-822902  0.371
2004 Baba T, Takai S, Sawada N, Isobe M. Stereoselective synthesis of the fully functionalized HIJ-ring framework of ciguatoxin Synlett. 2004: 603-608. DOI: 10.1055/S-2004-817769  0.376
2004 Nishiyama T, Ichikawa Y, Isobe M. Glycocinnasperimicin D Synthetic Studies: Synthesis of Cinnamoyl Glycosides via Iodination-Heck Reaction Sequence Starting from Phenyl Glycosides Synlett. 2004: 89-92. DOI: 10.1055/S-2003-43376  0.358
2004 Nishikawa T, Mishima Y, Ohyabu N, Isobe M. A novel stereoselective carbon-chain extension reaction at the C-6 position of 1,6-anhydropyranose Tetrahedron Letters. 45: 175-178. DOI: 10.1016/J.Tetlet.2003.10.135  0.36
2004 Ichikawa Y, Nishiyama T, Isobe M. Stereospecific synthesis of urea-tethered neoglycoconjugates starting from glucopyranosyl carbamates Tetrahedron. 60: 2621-2627. DOI: 10.1016/J.Tet.2004.01.055  0.376
2004 Kuse M, Kondo N, Ohyabu Y, Isobe M. Novel synthetic route of aryl-aminopyrazine Tetrahedron. 60: 835-840. DOI: 10.1016/J.Tet.2003.11.052  0.399
2003 Isobe M, Phoosaha W, Saeeng R, Kira K, Yenjai C. Different C-glycosidation products of glucal with alkynyl or propargyl silanes under acidic conditions. Organic Letters. 5: 4883-5. PMID 14653698 DOI: 10.1021/Ol035957W  0.323
2003 Ohyabu N, Nishikawa T, Isobe M. First asymmetric total synthesis of tetrodotoxin. Journal of the American Chemical Society. 125: 8798-805. PMID 12862474 DOI: 10.1021/Ja0342998  0.453
2003 Takai S, Sawada N, Isobe M. Convergent synthesis of the E'FGH ring fragment of ciguatoxin 1B via an acetylene cobalt complex strategy. The Journal of Organic Chemistry. 68: 3225-31. PMID 12688794 DOI: 10.1021/Jo034021Y  0.358
2003 Baba T, Isobe M. Synthesis of JKLM Ring Fragment of Ciguatoxin via Acetylene-Cobalt Strategy Synlett. 2003: 547-551. DOI: 10.1055/S-2003-37533  0.397
2003 Baba T, Huang G, Isobe M. Synthesis of the JKLM-ring fragment of ciguatoxin Tetrahedron. 59: 6851-6872. DOI: 10.1016/S0040-4020(03)00873-1  0.408
2003 Kurono M, Isobe M. A practical semi-synthesis of tautomycin using a hydrolysate of natural tautomycin Tetrahedron. 59: 9609-9617. DOI: 10.1016/J.Tet.2003.09.097  0.37
2003 Ichikawa Y, Ito T, Nishiyama T, Isobe M. Stereoselective Allyl Amine Synthesis via Enantioselective Addition of Diethylzinc and Sigmatropic Rearrangement. Synthesis of Lentiginosine. Cheminform. 34. DOI: 10.1002/CHIN.200341212  0.31
2002 Nishikawa T, Wada K, Isobe M. Synthesis of novel alpha-C-glycosylamino acids and reverse regioselectivity in Larock's heteroannulation for the synthesis of the indole nucleus. Bioscience, Biotechnology, and Biochemistry. 66: 2273-8. PMID 12450149 DOI: 10.1271/Bbb.66.2273  0.306
2002 Nishikawa T, Urabe D, Yoshida K, Iwabuchi T, Asai M, Isobe M. Stereocontrolled synthesis of 8,11-dideoxytetrodotoxin, unnatural analogue of puffer fish toxin. Organic Letters. 4: 2679-82. PMID 12153208 DOI: 10.1021/Ol026177A  0.414
2002 Nishikawa T, Asai M, Isobe M. Asymmetric total synthesis of 11-deoxytetrodotoxin, a naturally occurring congener. Journal of the American Chemical Society. 124: 7847-52. PMID 12083939 DOI: 10.1021/Ja0265153  0.365
2002 Takai S, Isobe M. Convergent synthesis of the E'FGH' ring fragment of ciguatoxin 1B via an acetylene cobalt complex strategy. Organic Letters. 4: 1183-6. PMID 11922813 DOI: 10.1021/Ol0256264  0.365
2002 Nishikawa T, Kajii S, Wada K, Ishikawa M, Isobe M. Scandium Perchlorate as a Superior Lewis Acid for Regioselective Ring Opening of Aziridine Carboxylate with Indoles Synthesis. 2002: 1658-1662. DOI: 10.1055/S-2002-33645  0.364
2002 Kira K, Hamajima A, Isobe M. Synthesis of the BCD-ring of ciguatoxin 1B using an acetylene cobalt complex and vinylsilane strategy Tetrahedron. 58: 1875-1888. DOI: 10.1016/S0040-4020(02)00044-3  0.394
2001 Ichikawa Y, Ohbayashi M, Hirata K, Nishizawa R, Isobe M. Synthesis of Blastidic Acid and Cytosinine, Two Components of Blasticidin S Synlett. 2001: 1763-1766. DOI: 10.1055/S-2001-18108  0.32
2001 Kira K, Isobe M. Synthesis of the BCDE rings of ciguatoxin 1B via an acetylene biscobalthexacarbonyl–vinylsilane strategy Tetrahedron Letters. 42: 2821-2824. DOI: 10.1016/S0040-4039(01)00286-6  0.372
2001 Huang G, Isobe M. Stereoselective synthesis of sugar allenes and their hydrosilylation catalyzed by biscobaltoctacarbonyl Tetrahedron. 57: 10241-10246. DOI: 10.1016/S0040-4020(01)01066-3  0.309
2001 Asai M, Nishikawa T, Ohyabu N, Yamamoto N, Isobe M. Stereocontrolled synthesis of (−)-5,11-dideoxytetrodotoxin Tetrahedron. 57: 4543-4558. DOI: 10.1016/S0040-4020(01)00382-9  0.428
2001 Nishikawa T, Asai M, Ohyabu N, Yamamoto N, Fukuda Y, Isobe M. Synthesis of a common key intermediate for (−)-tetrodotoxin and its analogs Tetrahedron. 57: 3875-3883. DOI: 10.1016/S0040-4020(01)00258-7  0.409
2000 Isobe M, Kira K. New Synthesis with Acetylene Biscobalthexacarbonyl Complex (2) Journal of Synthetic Organic Chemistry Japan. 58: 99-107. DOI: 10.5059/Yukigoseikyokaishi.58.99  0.415
2000 Isobe M, Kira K. New Synthesis with Acetylene Biscobalthexacarbonyl Complex (1) Journal of Synthetic Organic Chemistry Japan. 58: 23-30. DOI: 10.5059/Yukigoseikyokaishi.58.23  0.428
2000 Liu T, Isobe M. Synthesis of the H-I-J Tricyclic Fragment of Ciguatoxin, a Marine Polyether Toxin Synlett. 2000: 266-268. DOI: 10.1055/S-2000-6507  0.31
2000 Kira K, Isobe M. Acetylene cobalt complex and vinylsilane strategy in the synthesis of ciguatoxin (D)EF analog Tetrahedron Letters. 41: 5951-5955. DOI: 10.1016/S0040-4039(00)00988-6  0.356
2000 Liu T, Li J, Isobe M. Synthetic Studies on Ciguatoxin—Synthesis of H-I-J Ring System Tetrahedron. 56: 10209-10219. DOI: 10.1016/S0040-4020(00)00865-6  0.395
2000 Liu T, Isobe M. Synthetic Studies on the HIJK-Ring Fragment of Ciguatoxin Tetrahedron. 56: 5391-5404. DOI: 10.1016/S0040-4020(00)00467-1  0.403
2000 Kuse M, Isobe M. Synthesis of 13C-Dehydrocoelenterazine and NMR Studies on the Bioluminescence of a Symplectoteuthis Model Tetrahedron. 56: 2629-2639. DOI: 10.1016/S0040-4020(00)00163-0  0.351
1999 Nishikawa T, Isobe M. Palladium-catalyzed Substitution Reaction of Allylic Derivatives with Tinacetylene Bioscience, Biotechnology, and Biochemistry. 63: 238-242. PMID 27392881 DOI: 10.1271/Bbb.63.238  0.346
1999 Nishikawa T, Asai M, Ohyabu N, Yamamoto N, Isobe M. Stereocontrolled Synthesis of (-)-5,11-Dideoxytetrodotoxin. Angewandte Chemie. 38: 3081-3084. PMID 10540429 DOI: 10.1002/(Sici)1521-3773(19991018)38:20<3081::Aid-Anie3081>3.0.Co;2-6  0.409
1999 Isobe M, Nishizawa R, Nishikawa T, Yoza K. Hydrosilylation of acetylenes with catalytic biscobalthexacarbonyl complex and its application to heteroconjugate addition methodology Tetrahedron Letters. 40: 6927-6932. DOI: 10.1016/S0040-4039(99)01228-9  0.359
1999 Saeeng R, Isobe M. Partial synthesis of ciguatoxin (5R)-ABC segment Tetrahedron Letters. 40: 1911-1914. DOI: 10.1016/S0040-4039(99)00041-6  0.342
1999 Nishikawa T, Ohyabu N, Yamamoto N, Isobe M. New synthetic route of guanidine from trichloroacetamide for tetrodotoxin and its related compounds Tetrahedron. 55: 4325-4340. DOI: 10.1016/S0040-4020(99)00140-4  0.322
1999 Isobe M, Takai S. First Pauson–Khand reaction on sugar acetylenes Journal of Organometallic Chemistry. 589: 122-125. DOI: 10.1016/S0022-328X(99)00320-4  0.37
1998 Nishikawa T, Araki H, Isobe M. Novel Stereoselective Reaction of Levoglucosenone with Furfural. Bioscience, Biotechnology, and Biochemistry. 62: 190-192. PMID 27393369 DOI: 10.1271/Bbb.62.190  0.327
1998 Isobe M, Kuse M, Yasuda Y, Takahashi H. Synthesis of 13C-dehydrocoelenterazine and model studies on Symplectoteuthis squid bioluminescence Bioorganic & Medicinal Chemistry Letters. 8: 2919-2924. PMID 9873648 DOI: 10.1016/S0960-894X(98)00525-3  0.374
1998 Shibuya S, Isobe M. Versatile Synthesis of Bicyclo[9.3.1]pentadecatriene for New Bicyclic Taxoids Synlett. 1998: 373-374. DOI: 10.1055/S-1998-1683  0.376
1998 Bamba M, Nishikawa T, Isobe M. Stereoelectronic and steric control in chiral cyclohexane synthesis toward (−)-tetrodotoxin Tetrahedron. 54: 6639-6650. DOI: 10.1016/S0040-4020(98)00331-7  0.396
1998 Yenjai C, Isobe M. One-step recyclization of sugar acetylenes to form medium ether rings via dicobalthexacarbonyl complexes Tetrahedron. 54: 2509-2520. DOI: 10.1016/S0040-4020(98)00013-1  0.335
1997 Unno R, Michishita H, Inagaki H, Suzuki Y, Baba Y, Jomori T, Nishikawa T, Isobe M. Synthesis and antitumor activity of water-soluble enediyne compounds related to dynemicin a Bioorganic & Medicinal Chemistry. 5: 987-999. PMID 9208107 DOI: 10.1016/S0968-0896(97)00037-0  0.337
1997 Unno R, Michishita H, Inagaki H, Suzuki Y, Baba Y, Jomori T, Moku M, Nishikawa T, Isobe M. Structure-activity relationships of cyclic enediynes related to dynemicin A—II. Synthesis and antitumor activity of 9- and 12-substituted enediynes equipped with aryl carbamate moieties Bioorganic & Medicinal Chemistry. 5: 883-901. PMID 9208100 DOI: 10.1016/S0968-0896(97)00026-6  0.349
1997 Unno R, Michishita H, Inagaki H, Baba Y, Jomori T, Nishikawa T, Isobe M. Synthesis and Biological Evaluation of Novel Cyclic Enediyne Compounds Related to Dynemicin A as Antitumor Agents Chemical & Pharmaceutical Bulletin. 45: 125-133. PMID 9023974 DOI: 10.1248/Cpb.45.125  0.311
1997 Isobe M, Tsuboi K, Hosokawa S, Bamba M, Kira K, Shibuya S, Ohtani II, Nishikawa T, Ichikawa Y. Enzyme inhibitors, synthesis and approach to mechanism Pure and Applied Chemistry. 69: 401-406. DOI: 10.1351/Pac199769030401  0.334
1997 Tsuboi K, Ichikawa Y, Isobe M. Synthesis Of Okadaic Acid-Tautomycin Hybrid Synlett. 1997: 713-715. DOI: 10.1055/S-1997-3257  0.337
1996 Tomoo T, Kondo T, Abe H, Tsukamoto S, Isobe M, Goto T. An efficient short-step total synthesis of ganglioside GM3: effective usage of the neighbouring group participation strategy Carbohydrate Research. 284: 207-222. PMID 8653720 DOI: 10.1016/0008-6215(96)00015-8  0.36
1996 Hosokawa S, Isobe M. Partial Synthesis of Ciguatoxin, an A/B/C Fragment Synlett. 1996: 351-352. DOI: 10.1055/S-1996-5436  0.329
1996 Bamba M, Nishikawa T, Isobe M. Tin-assisted cyclization for chiral cyclohexane synthesis, an alternative route to (−)-tetrodotoxin skeleton Tetrahedron Letters. 37: 8199-8202. DOI: 10.1016/0040-4039(96)01860-6  0.377
1996 Usami K, Isobe M. Low-temperature photooxygenation of coelenterate luciferin analog synthesis and proof of 1,2-dioxetanone as luminescence intermediate☆ Tetrahedron. 52: 12061-12090. DOI: 10.1016/0040-4020(96)00699-0  0.345
1995 Kawai T, Isobe M, Peters S. Factors Affecting Reaction of 1,6-Anhydrohexos-2-ulose Derivatives Australian Journal of Chemistry. 48: 115-131. DOI: 10.1071/Ch9950115  0.337
1995 Yamamoto N, Nishikawa T, Isobe M. Synthesis of Bicyclic Hydroxy Lactone Intermediates toward (-)-Tetrodotoxin Synlett. 1995: 505-506. DOI: 10.1055/S-1995-5269  0.432
1995 Hosokawa S, Isobe M. Synthesis Of Two Diastereoisomers Of A/B Fragment Of Ciguatoxin Synlett. 1995: 1179-1180. DOI: 10.1055/S-1995-5225  0.317
1995 Jiang Y, Ichikawa Y, Isobe M. Synthesis Of Segment C Of Tautomycin Synlett. 1995: 285-288. DOI: 10.1055/S-1995-4937  0.327
1995 Tsuboi K, Ichikawa Y, Jiang Y, Naganawa A, Isobe M. Total Synthesis Of (+)-Tautomycin Tetrahedron. 36: 5123-5142. DOI: 10.1016/S0040-4020(97)00230-5  0.351
1995 Nishikawa T, Yoshikai M, Obi K, Kawai T, Unno R, Jomori T, Isobe M. Synthesis and biological evaluation of both enantiomers of dynemicin a model compound Tetrahedron. 51: 9339-9352. DOI: 10.1016/0040-4020(95)00521-9  0.381
1995 Okita T, Isobe M. Palladium-catalyzed coupling of heteroaromatic triflates with acetylene and its application for a dynemicin a intermediate Tetrahedron. 51: 3737-3744. DOI: 10.1016/0040-4020(95)00118-R  0.362
1994 Suwan S, Isobe M, Yamashita O, Minakata H, Imai K. Silkworm diapause hormone, structure-activity relationships indispensable role of C-terminal amide. Insect Biochemistry and Molecular Biology. 24: 1001-7. PMID 7703983 DOI: 10.1016/0965-1748(94)90137-6  0.32
1994 Isobe M. Sugar Acetylene for New Stereocontrolled Synthesis Journal of Synthetic Organic Chemistry Japan. 52: 968-979. DOI: 10.5059/Yukigoseikyokaishi.52.968  0.41
1994 Ichikawa Y, Kobayashi C, Isobe M. Synthesis of Nitrogen-containing Unsaturated Carbohydrates through an Allyl Cyanate-to-isocyanate Rearrangement Synlett. 1994: 919-921. DOI: 10.1055/S-1994-23048  0.419
1994 Nishikawa T, Shibuya S, Hosokawa S, Isobe M. One Pot Synthesis of Haloacetylenes from Trimethylsilylacetylenes Synlett. 1994: 485-486. DOI: 10.1055/S-1994-22897  0.401
1994 Nishikawa T, Shibuya S, Isobe M. Cesium Fluoride Promoted Cyclization in the Synthesis of Enediyne Antibiotics1 Synlett. 1994: 482-484. DOI: 10.1055/S-1994-22896  0.385
1994 Teranishi K, Isobe M, Yamada T. Synthesis of silyl peroxide of coelenterazine (oplophorus luciferin) analogue for precursor of luminescence Tetrahedron Letters. 35: 2565-2568. DOI: 10.1016/S0040-4039(00)77172-3  0.398
1994 Nishikawa T, Isobe M. Synthetic studies on dynemicin A. New quinoline synthesis for C, D and E rings. Tetrahedron. 50: 5621-5632. DOI: 10.1016/S0040-4020(01)85633-7  0.414
1994 Naganawa A, Ichikawa Y, Isobe M. Synthetic studies on tautomycin : synthesis of 2,3-disubstituted maleic anhydride segment Tetrahedron. 50: 8969-8982. DOI: 10.1016/S0040-4020(01)85365-5  0.349
1994 Nishikawa T, Ino A, Isobe M. Synthetic studies on antibiotic dynemicin A. Synthesis of cyclic enediyne model compound of dynemicin A Tetrahedron. 50: 1449-1468. DOI: 10.1016/S0040-4020(01)80629-3  0.365
1994 Tanaka S, Isobe M. Opening of dihydropyran and recyclizing to dehydrooxepane through C-1 alkynyl cobalt complex—A new method toward marine polyether toxins Tetrahedron Letters. 35: 7801-7804. DOI: 10.1016/0040-4039(94)80122-3  0.355
1994 Nishikawa T, Yoshikai M, Obi K, Isobe M. Synthesis of both enantiomers of dynemicin a model compound. New remote asymmetric induction in acetylide addition into quinoline nucleus as key step Tetrahedron Letters. 35: 7997-8000. DOI: 10.1016/0040-4039(94)80032-4  0.377
1992 Takai A, Murata M, Torigoe K, Isobe M, Mieskes G, Yasumoto T. Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship. The Biochemical Journal. 539-44. PMID 1318034 DOI: 10.1042/Bj2840539  0.305
1992 Toya Y, Takagi M, Nakata H, Suzuki N, Isobe M, Goto T. A Convenient Synthetic Method of 2-Cyano-6-methoxybenzothiazole, –A Key Intermediate for the Synthesis of Firefly Luciferin Bulletin of the Chemical Society of Japan. 65: 392-395. DOI: 10.1246/Bcsj.65.392  0.413
1992 Toya Y, Takagi M, Kondo T, Nakata H, Isobe M, Goto T. Improved Synthetic Methods of Firefly Luciferin Derivatives for Use in Bioluminescent Analysis of Hydrolytic Enzymes; Carboxylic Esterase and Alkaline Phosphatase. Bulletin of the Chemical Society of Japan. 65: 2604-2610. DOI: 10.1246/Bcsj.65.2604  0.343
1992 Teranishi K, Isobe M, Yamada T, Goto T. Revision of structure of yellow compound, a reduction product from aequorin, photoprotein in jellyfish, Aequorea aequorea Tetrahedron Letters. 33: 1303-1306. DOI: 10.1016/S0040-4039(00)91607-1  0.343
1992 Isobe M, Nishikawa T, Yamamoto N, Tsukiyama T, Ino A, Okita T. Methodologies for synthesis of heterocyclic compounds Journal of Heterocyclic Chemistry. 29: 619-625. DOI: 10.1002/Jhet.5570290303  0.355
1991 Nishikawa T, Ino A, Isobe M, Goto T. Synthesis of a Simple Model Compound of Dynemicin and Cycloaromatization with Pinacol-Pinacolone Rearrangement in the Strained Enediyne Medium Ring. Chemistry Letters. 20: 1271-1274. DOI: 10.1246/Cl.1991.1271  0.417
1991 Herunsalee A, Isobe M, Pikul S, Goto T. Stereoselective Synthesis Directed Toward Polyoxygenated Compounds: Synthesis of a 3-Deoxy-D-galacto-nonulosonic Acid (KDN) Equivalent Synlett. 1991: 199-202. DOI: 10.1055/S-1991-20679  0.4
1990 Isobe M, Nishikawa T, Herunsalee A, Tsukiyama T, Hirose Y, Shimokawa K, Goto T. Methodology for stereochemical control in bioactive natural product synthesis - new methods toward enediyne antitumor antibiotics Pure and Applied Chemistry. 62: 2007-2012. DOI: 10.1351/Pac199062102007  0.411
1990 Isobe M, Hirose Y, Shimokawa K, Nishikawa T, Goto T. Asymmetric synthesis via heteroconjugate addition: valinol template as oxazolidine heteroolefin vs acetylenic nucleophiles Tetrahedron Letters. 31: 5499-5502. DOI: 10.1016/S0040-4039(00)97882-1  0.412
1990 Isobe M, Takahashi H, Goto T. Lampteromyces bioluminescence — 5 chemical synthesis of lampteroflavin as mushroom light emitter Tetrahedron Letters. 31: 717-718. DOI: 10.1016/S0040-4039(00)94611-2  0.333
1990 Isobe M, Fukuda Y, Nishikawa T, Chabert P, Kawai T, Goto T. Synthetic studies on (−)-tetrodotoxin (3) nitrogenation through overman rearrangement and guanidine ring formation Tetrahedron Letters. 31: 3327-3330. DOI: 10.1016/S0040-4039(00)89056-5  0.363
1987 Isobe M, Fukami N, Nishikawa T, Foto T. Synthesis of chiral cyclohexanes from levoglucosenone and its application to an indole alkaloid reserpine Heterocycles. 25: 521-532. DOI: 10.3987/S-1987-01-0521  0.367
1987 Isobe M, Nishikawa T, Fukami N, Goto T. Synthetic studies on a stereochemically complex natural product: designs for the total synthesis of (-)-tetrodotoxin Pure and Applied Chemistry. 59: 399-406. DOI: 10.1351/Pac198759030399  0.321
1987 Isobe M, Nishikawa T, Pikul S, Goto T. Synthetic studies on tetrodotoxin (1) stereocontrolled synthesis of the cyclohexane moiety Tetrahedron Letters. 28: 6485-6488. DOI: 10.1016/S0040-4039(00)96895-3  0.38
1987 Isobe M, Ichikawa Y, Bai D, Masaki H, Goto T. Synthesis of a marine polyether toxin, okadaic acid [4]p1 -- total synthesis Tetrahedron. 43: 4767-4776. DOI: 10.1016/S0040-4020(01)86918-0  0.389
1987 Ichikawa Y, Isobe M, Masaki H, Kawai T, Goto T. Synthesis of a marine polyether toxin, okadaic acid (3) — synthesis of segment c Tetrahedron. 43: 4759-4766. DOI: 10.1016/S0040-4020(01)86917-9  0.362
1987 Ichikawa Y, Isobe M, Goto T. Synthesis of a marine polyether toxin, okadaic acid (2) — synthesis of segment b Tetrahedron. 43: 4749-4758. DOI: 10.1016/S0040-4020(01)86916-7  0.375
1987 Ichikawa Y, Isobe M, Bai D, Goto T. Synthesis of a marine polyether toxin, okadaic acid [1] — strategy and synthesis of segment a Tetrahedron. 43: 4737-4748. DOI: 10.1016/S0040-4020(01)86915-5  0.364
1987 Ichikawa Y, Isobe M, Konobe M, Goto T. Synthesis of C-glycosyl compounds from 3,4,6-tri-O-acetyl-1,5-anhydro-D-arabino-hex-1-enitol and allyltrimethylsilane and bis(trimethylsilyl)acetylene Carbohydrate Research. 171: 193-199. DOI: 10.1016/S0008-6215(00)90886-3  0.371
1986 Isobe M, Ichikawa Y. Total Synthesis of a Marine Toxic Polyether, Okadaic Acid Journal of Synthetic Organic Chemistry Japan. 44: 1155-1168. DOI: 10.5059/Yukigoseikyokaishi.44.1155  0.347
1986 Isobe M, Ichikawa Y, Goto T. Synthetic studies toward marine toxic polyethers [5] the total synthesis of okadaic acid Tetrahedron Letters. 27: 963-966. DOI: 10.1016/S0040-4039(00)84149-0  0.384
1986 Isobe M, Ichikawa Y, Funabashi Y, Mio S, Goto T. Acyclic stereocontrol by heteroconjugate addition—4 : Anti-diastereoselection by a β-chelation effect Tetrahedron. 42: 2863-2872. DOI: 10.1016/S0040-4020(01)90575-7  0.378
1985 Isobe M, Fukami N, Goto T. New strategy for chiral alkaloid synthesis commencing with a carbohydrate. Simple synthesis of (-)-allo-yohimbane from levoglucosenone. Chemistry Letters. 14: 71-74. DOI: 10.1246/Cl.1985.71  0.418
1985 Isobe M, Ichikawa Y, Bai D, Goto T. Synthetic studies toward marine toxic polyethers (4) synthesis of segment -A of okadaic acid via -selectivity by heteroconjugate addition Tetrahedron Letters. 26: 5203-5206. DOI: 10.1016/S0040-4039(00)98903-2  0.347
1985 Isobe M, Ichikawa Y, Goto T. Synthetic studies toward marine toxic polyethers (3) stereocontrol for segment-A1 of okadaic acid by means of oxymercuration and epoxydation Tetrahedron Letters. 26: 5199-5202. DOI: 10.1016/S0040-4039(00)98902-0  0.303
1984 Ichikawa Y, Isobe M, Goto T. Synthetic studies toward marine toxic polyethers (2) synthesis of the B-segment of okadaic acid and coupling with the C-segment Tetrahedron Letters. 25: 5049-5052. DOI: 10.1016/S0040-4039(01)91116-5  0.343
1984 Isobe M, Ichikawa Y, Masaki H, Goto T. Synthetic studies toward marine toxic polyethers (1) a stereocontrolled synthesis of the C-segnent of okadaic acid Tetrahedron Letters. 25: 3607-3610. DOI: 10.1016/S0040-4039(01)91087-1  0.391
1984 Isobe M, Funabashi Y, Ichikawa Y, Mio S, Goto T. Acyclic stereocontrol by heteroconjugate addition — 3 : Diastereoselective synthesis of either syn or anti diastereoisomer Tetrahedron Letters. 25: 2021-2024. DOI: 10.1016/S0040-4039(01)90102-9  0.396
1984 Isobe M, Fukami N, Goto T. Darzens Condensation for Stereocontrol in Sugar Template. Cheminform. 15: 369. DOI: 10.1002/Chin.198439148  0.302
1983 Isobe M. Stereocontrolled Total Syntheses of Maytansinoids Journal of Synthetic Organic Chemistry Japan. 41: 51-61. DOI: 10.5059/Yukigoseikyokaishi.41.51  0.377
1981 Isobe M, Ichikawa Y, Goto T. Total synthesis of (+)-prelog-djerassi lactonic acid Tetrahedron Letters. 22: 4287-4290. DOI: 10.1016/S0040-4039(01)82936-1  0.355
1980 Isobe M, Kitamura M, Goto T. Acyclic asymmetric induction with carboncarbon bond formation Tetrahedron Letters. 21: 4727-4730. DOI: 10.1016/0040-4039(80)88105-6  0.305
1979 Isobe M, Iio H, Goto T. Stereochemical Control in the Conjugate Reduction and A New Method for cis-α-Methylene-ϒ-butyrolactone Formation Agricultural and Biological Chemistry. 43: 2119-2123. DOI: 10.1271/Bbb1961.43.2119  0.334
1979 Iio H, Isobe M, Kawai T, Goto T. Total synthesis of vernolepin—I : Synthesis of the key intermediate Tetrahedron. 35: 941-948. DOI: 10.1016/S0040-4020(01)93706-8  0.392
1978 Isobe M, Iio H, Kitamura M, Goto T. Substituent effects on the ratio of [2,3]-sigmatropic rearrangement vs syn-elimination of allylic aryl sulfoxides. Chemistry Letters. 7: 541-544. DOI: 10.1246/Cl.1978.541  0.322
1978 Isobe M, Iio H, Kitamura M, Goto T. Synthesis Of Sesquiterpene Antitumor Lactones. Part 3. Substituent Effects On N The Ratio Of (2,3)-Sigmatropic Rearrangement Vs Syn-Elimination Of Allylic Aryl Sulfoxides Cheminform. 9. DOI: 10.1002/Chin.197843229  0.368
1977 Isobe M, Iio H, Kawai T, Goto T. Synthesis of sesquiterpene antitumor lactones I a facile synthesis of -fused-a-ring in vernolepin and vernomenin Tetrahedron Letters. 18: 703-706. DOI: 10.1016/S0040-4039(01)92731-5  0.411
1975 Stork G, Isobe M. Letter: A simple total synthesis of prostaglandins from 4-cumyloxy-2-cyclopentenone. Journal of the American Chemical Society. 97: 6260-1. PMID 1176736 DOI: 10.1021/Ja00854A061  0.382
1968 Isobe M, Goto T. Synthesis of grifolin, an antibiotic from a Basidiomycete. Tetrahedron. 24: 945-948. PMID 5637493 DOI: 10.1016/0040-4020(68)88044-5  0.391
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