| Year |
Citation |
Score |
| 2023 |
Cornista AM, Giolito MV, Baker K, Hazime H, Dufait I, Datta J, Khumukcham SS, De Ridder M, Roper J, Abreu MT, Breckpot K, Van der Jeught K. Colorectal Cancer Immunotherapy: State of the Art and Future Directions. Gastro Hep Advances. 2: 1103-1119. PMID 38098742 DOI: 10.1016/j.gastha.2023.09.007 |
0.303 |
|
| 2023 |
Schmidt DR, Gramatikov IMT, Sheen A, Williams CL, Hurwitz M, Dodge LE, Holupka E, Kiger WS, Cornwall-Brady MR, Huang W, Mak HH, Cormier KS, Condon C, Dane Wittrup K, Yilmaz ÖH, ... ... Roper J, et al. Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer. Communications Medicine. 3: 108. PMID 37558833 DOI: 10.1038/s43856-023-00336-3 |
0.499 |
|
| 2022 |
Sedlak JC, Yilmaz ÖH, Roper J. Metabolism and Colorectal Cancer. Annual Review of Pathology. PMID 36323004 DOI: 10.1146/annurev-pathmechdis-031521-041113 |
0.556 |
|
| 2022 |
Sullivan BA, Noujaim M, Roper J. Cause, Epidemiology, and Histology of Polyps and Pathways to Colorectal Cancer. Gastrointestinal Endoscopy Clinics of North America. 32: 177-194. PMID 35361330 DOI: 10.1016/j.giec.2021.12.001 |
0.305 |
|
| 2021 |
Wu X, Ueland PM, Roper J, Koh GY, Liang X, Crott JW, Yilmaz ÖH, Bronson RT, Mason JB. Combined Supplementation with Vitamin B-6 and Curcumin is Superior to Either Agent Alone in Suppressing Obesity-Promoted Colorectal Tumorigenesis in Mice. The Journal of Nutrition. PMID 34590119 DOI: 10.1093/jn/nxab320 |
0.498 |
|
| 2021 |
Beyaz S, Chung C, Mou H, Bauer-Rowe KE, Xifaras ME, Ergin I, Dohnalova L, Biton M, Shekhar K, Eskiocak O, Papciak K, Ozler K, Almeqdadi M, Yueh B, Fein M, ... ... Roper J, et al. Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis. Cell Stem Cell. PMID 34529935 DOI: 10.1016/j.stem.2021.08.007 |
0.695 |
|
| 2020 |
Joseph A, Roper J. Genetic evidence that a gut commensal bacterium can cause colorectal cancer. Gastroenterology. PMID 33310089 DOI: 10.1053/j.gastro.2020.12.014 |
0.319 |
|
| 2020 |
Han H, Davidson LA, Fan YY, Goldsby JS, Yoon G, Jin UH, Wright GA, Landrock KK, Weeks BR, Wright RC, Allred CD, Jayaraman A, Ivanov I, Roper J, Safe SH, et al. Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic stem and progenitor cells. The Embo Journal. e104319. PMID 32915464 DOI: 10.15252/Embj.2019104319 |
0.395 |
|
| 2020 |
Cheung P, Xiol J, Dill MT, Yuan WC, Panero R, Roper J, Osorio FG, Maglic D, Li Q, Gurung B, Calogero RA, Yilmaz ÖH, Mao J, Camargo FD. Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer. Cell Stem Cell. PMID 32730753 DOI: 10.1016/J.Stem.2020.07.003 |
0.634 |
|
| 2020 |
Cheltsov A, Nomura N, Yenugonda VM, Roper J, Mukthavaram R, Jiang P, Her NG, Babic I, Kesari S, Nurmemmedov E. Allosteric inhibitor of β-catenin selectively targets oncogenic Wnt signaling in colon cancer. Scientific Reports. 10: 8096. PMID 32415084 DOI: 10.1038/S41598-020-60784-Y |
0.303 |
|
| 2020 |
Tschurtschenthaler M, Silva MG, Jesinghaus M, Sinha A, Roper J, Rad R, Saur D. Abstract 1116: Spatio-temporal analysis of the tumor microenvironment of colorectal cancer subtypes using an orthotopic organoid transplantation model Cancer Research. 80: 1116-1116. DOI: 10.1158/1538-7445.Am2020-1116 |
0.439 |
|
| 2019 |
Hynes RO, Rickelt S, Condon C, Mana M, Whittaker C, Pfirschke C, Roper J, Patil DT, Brown I, Mattia AR, Zukerberg L, Zhao Q, Chetty R, Lauwers GY, Neyaz A, et al. Agrin in the Muscularis Mucosa Serves as a Biomarker Distinguishing Hyperplastic Polyps from Sessile Serrated Lesions. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31852835 DOI: 10.1158/1078-0432.Ccr-19-2898 |
0.517 |
|
| 2019 |
Jackstadt R, van Hooff SR, Leach JD, Cortes-Lavaud X, Lohuis JO, Ridgway RA, Wouters VM, Roper J, Kendall TJ, Roxburgh CS, Horgan PG, Nixon C, Nourse C, Gunzer M, Clark W, et al. Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis. Cancer Cell. 36: 319-336.e7. PMID 31526760 DOI: 10.1016/J.Ccell.2019.08.003 |
0.6 |
|
| 2019 |
Pentinmikko N, Iqbal S, Mana M, Andersson S, Cognetta AB, Suciu RM, Roper J, Luopajärvi K, Markelin E, Gopalakrishnan S, Smolander OP, Naranjo S, Saarinen T, Juuti A, Pietiläinen K, et al. Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium. Nature. PMID 31292548 DOI: 10.1038/S41586-019-1383-0 |
0.641 |
|
| 2019 |
Almeqdadi M, Mana MD, Roper J, Yilmaz ÖH. Gut Organoids: Mini-Tissues in Culture to Study Intestinal Physiology and Disease. American Journal of Physiology. Cell Physiology. PMID 31216420 DOI: 10.1152/Ajpcell.00300.2017 |
0.589 |
|
| 2019 |
Roper J, Yilmaz ÖH. Breakthrough Moments: Genome Editing and Organoids. Cell Stem Cell. 24: 841-842. PMID 31173713 DOI: 10.1016/J.Stem.2019.05.008 |
0.48 |
|
| 2019 |
Roper J, Sheng X. Novel Patient-Derived Cultures of Patient-Derived Cancer and Tumor Immune Cells. Gastroenterology. PMID 31136743 DOI: 10.1053/J.Gastro.2019.05.036 |
0.352 |
|
| 2019 |
Peng B, Almeqdadi M, Laroche F, Palantavida S, Dokukin M, Roper J, Yilmaz OH, Feng H, Sokolov I. Ultrabright fluorescent cellulose acetate nanoparticles for imaging tumors through systemic and topical applications. Materials Today (Kidlington, England). 23: 16-25. PMID 31057328 DOI: 10.1016/J.Mattod.2018.11.001 |
0.501 |
|
| 2019 |
Chan EM, Shibue T, McFarland JM, Gaeta B, Ghandi M, Dumont N, Gonzalez A, McPartlan JS, Li T, Zhang Y, Bin Liu J, Lazaro JB, Gu P, Piett CG, Apffel A, ... ... Roper J, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. PMID 30971823 DOI: 10.1038/S41586-019-1102-X |
0.362 |
|
| 2019 |
Goncalves MD, Lu C, Tutnauer J, Hartman TE, Hwang SK, Murphy CJ, Pauli C, Morris R, Taylor S, Bosch K, Yang S, Wang Y, Van Riper J, Lekaye HC, Roper J, et al. High-fructose corn syrup enhances intestinal tumor growth in mice. Science (New York, N.Y.). 363: 1345-1349. PMID 30898933 DOI: 10.1126/Science.Aat8515 |
0.36 |
|
| 2019 |
Peng B, Almeqdadi M, Laroche F, Palantavida S, Dokukin M, Roper J, Yilmaz OH, Feng H, Sokolov I. Data on ultrabright fluorescent cellulose acetate nanoparticles for imaging tumors through systemic and topical applications. Data in Brief. 22: 383-391. PMID 30596135 DOI: 10.1016/J.Dib.2018.12.030 |
0.477 |
|
| 2019 |
Schmidt DR, Roper J, Santos S, Yilmaz OH, Heiden MGV. 453 – Therapeutic Dose of Pelvic Radiation Slows Tumor Growth and Improves Survival in a Genetically Engineered Mouse Model of Colorectal Cancer Gastroenterology. 156: S-95. DOI: 10.1016/S0016-5085(19)37026-X |
0.56 |
|
| 2018 |
Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, et al. Author Correction: High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature. PMID 29849139 DOI: 10.1038/S41586-018-0187-Y |
0.713 |
|
| 2018 |
Koh GY, Kane A, Lee K, Xu Q, Wu X, Roper J, Mason JB, Crott JW. Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice. International Journal of Cancer. PMID 29696632 DOI: 10.1002/Ijc.31559 |
0.352 |
|
| 2018 |
Lannagan TRM, Lee YK, Wang T, Roper J, Bettington ML, Fennell L, Vrbanac L, Jonavicius L, Somashekar R, Gieniec K, Yang M, Ng JQ, Suzuki N, Ichinose M, Wright JA, et al. Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis. Gut. PMID 29666172 DOI: 10.1136/Gutjnl-2017-315920 |
0.558 |
|
| 2018 |
Roper J, Tammela T, Akkad A, Almeqdadi M, Santos SB, Jacks T, Yilmaz ÖH. Colonoscopy-based colorectal cancer modeling in mice with CRISPR-Cas9 genome editing and organoid transplantation. Nature Protocols. 13: 217-234. PMID 29300388 DOI: 10.1038/Nprot.2017.136 |
0.625 |
|
| 2018 |
Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli M, Sánchez-Rivera F, Park Y, Liang X, Eng G, Taylor MS, Azimi R, et al. Abstract B38: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-B38 |
0.772 |
|
| 2017 |
Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, et al. Corrigendum: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nature Biotechnology. 35: 1211. PMID 29220013 DOI: 10.1038/Nbt1217-1211A |
0.745 |
|
| 2017 |
Lau AN, Israelsen WJ, Roper J, Sinnamon MJ, Georgeon L, Dayton TL, Hillis AL, Yilmaz OH, Di Vizio D, Hung KE, Vander Heiden MG. PKM2 is not required for colon cancer initiated by APC loss. Cancer & Metabolism. 5: 10. PMID 29214019 DOI: 10.1186/S40170-017-0172-1 |
0.602 |
|
| 2017 |
Roper J, Yilmaz ÖH. Metabolic Teamwork in the Stem Cell Niche. Cell Metabolism. 25: 993-994. PMID 28467944 DOI: 10.1016/J.Cmet.2017.04.019 |
0.537 |
|
| 2017 |
Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, et al. In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nature Biotechnology. PMID 28459449 DOI: 10.1038/Nbt.3836 |
0.771 |
|
| 2017 |
Kedrin D, Gandhi SC, Wolf M, Roper J, Yilmaz O, Corey K, Khalili H, Stanford FC, Gala M. Bariatric Surgery Prior to Index Screening Colonoscopy Is Associated With a Decreased Rate of Colorectal Adenomas in Obese Individuals. Clinical and Translational Gastroenterology. 8: e73. PMID 28181993 DOI: 10.1038/Ctg.2017.1 |
0.528 |
|
| 2017 |
Beytagh MC, Westcott PM, Smith OC, Roper J, Yilmaz O, Jacks TE. Abstract 5018: Dissecting antigen-specific T-cell response in a novel mouse model of colon cancer Cancer Research. 77: 5018-5018. DOI: 10.1158/1538-7445.Am2017-5018 |
0.572 |
|
| 2016 |
Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, et al. High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature. 531: 53-8. PMID 26935695 DOI: 10.1038/Nature17173 |
0.743 |
|
| 2016 |
Roper J, Tammela T, Cetinbas N, Sanchez-Rivera F, Almeqdadi M, Azimy R, Park Y, Kedrin D, Akkad A, Bauer-Rowe K, Neupane R, Yilmaz OH. 30 Sequential Genome Editing in CRISPR/Cas9-Based Colorectal Cancer Mouse Models Gastroenterology. 150: S10-S11. DOI: 10.1016/S0016-5085(16)30165-2 |
0.594 |
|
| 2015 |
Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, Muley A, Asara JM, Paik J, Elemento O, Chen Z, et al. Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science (New York, N.Y.). PMID 26541605 DOI: 10.1126/Science.Aaa5004 |
0.351 |
|
| 2015 |
Golovko D, Kedrin D, Yilmaz ÖH, Roper J. Colorectal cancer models for novel drug discovery. Expert Opinion On Drug Discovery. 1-13. PMID 26295972 DOI: 10.1517/17460441.2015.1079618 |
0.61 |
|
| 2014 |
Belmont PJ, Jiang P, McKee TD, Xie T, Isaacson J, Baryla NE, Roper J, Sinnamon MJ, Lee NV, Kan JL, Guicherit O, Wouters BG, O'Brien CA, Shields D, Olson P, et al. Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR. Science Signaling. 7: ra107. PMID 25389372 DOI: 10.1126/Scisignal.2005516 |
0.349 |
|
| 2014 |
Roper J, Martin ES, Hung KE. Overview of genetically engineered mouse models of colorectal carcinoma to enable translational biology and drug development. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. 65: 14.29.1-14.29.10. PMID 24934606 DOI: 10.1002/0471141755.Ph1429S65 |
0.436 |
|
| 2014 |
Belmont PJ, Budinska E, Jiang P, Sinnamon MJ, Coffee E, Roper J, Xie T, Rejto PA, Derkits S, Sansom OJ, Delorenzi M, Tejpar S, Hung KE, Martin ES. Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease. Disease Models & Mechanisms. 7: 613-23. PMID 24742783 DOI: 10.1242/Dmm.013904 |
0.422 |
|
| 2014 |
Roper J, Sinnamon MJ, Coffee EM, Belmont P, Keung L, Georgeon-Richard L, Wang WV, Faber AC, Yun J, Yilmaz ÖH, Bronson RT, Martin ES, Tsichlis PN, Hung KE. Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant colorectal cancer. Cancer Letters. 347: 204-11. PMID 24576621 DOI: 10.1016/J.Canlet.2014.02.018 |
0.387 |
|
| 2014 |
Faber AC, Coffee EM, Costa C, Dastur A, Ebi H, Hata AN, Yeo AT, Edelman EJ, Song Y, Tam AT, Boisvert JL, Milano RJ, Roper J, Kodack DP, Jain RK, et al. mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1. Cancer Discovery. 4: 42-52. PMID 24163374 DOI: 10.1158/2159-8290.Cd-13-0315 |
0.425 |
|
| 2014 |
Yun J, Kavalier A, Mullarky E, Bosch K, Roper J, Rago C, Paik J, Asara J, Gross S, Vogelstein B, Papadopoulos N, Cantley L. Abstract 2951: Vitamin C is selectively toxic to cancer cells harboring KRAS or BRAF mutations by targeting GAPDH Cancer Research. 74: 2951-2951. DOI: 10.1158/1538-7445.Am2014-2951 |
0.386 |
|
| 2013 |
Coffee EM, Faber AC, Roper J, Sinnamon MJ, Goel G, Keung L, Wang WV, Vecchione L, de Vriendt V, Weinstein BJ, Bronson RT, Tejpar S, Xavier RJ, Engelman JA, Martin ES, et al. Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 2688-98. PMID 23549875 DOI: 10.1158/1078-0432.Ccr-12-2556 |
0.381 |
|
| 2013 |
Martin ES, Belmont PJ, Sinnamon MJ, Richard LG, Yuan J, Coffee EM, Roper J, Lee L, Heidari P, Lunt SY, Goel G, Ji X, Xie Z, Xie T, Lamb J, et al. Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 2929-40. PMID 23403635 DOI: 10.1158/1078-0432.Ccr-12-2307 |
0.429 |
|
| 2013 |
Yun J, Kavalier A, Roper J, Gross S, Rago C, Papadopoulos N, Vogelstein B, Cantley L. Abstract C60: Vitamin C inhibits the survival and growth of colorectal cancer cells with KRAS or BRAF mutations Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C60 |
0.338 |
|
| 2013 |
Coffee EM, Faber AC, Costa C, Dastur A, Ebi H, Hata AN, Yeo AT, J E, Song Y, Tam AT, Boisvert JL, Milano RJ, Roper J, Kodack DP, Jain RK, et al. Abstract C263: mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C263 |
0.409 |
|
| 2012 |
Roper J, Hung KE. Priceless GEMMs: genetically engineered mouse models for colorectal cancer drug development. Trends in Pharmacological Sciences. 33: 449-55. PMID 22739258 DOI: 10.1016/J.Tips.2012.05.001 |
0.441 |
|
| 2012 |
Coffee EM, Roper J, Sinnamon MJ, Belmont P, Keung L, Wang WV, Richard LG, Goel G, Weinstein BJ, Bronson RT, Xavier R, Martin ES, Hung KE. 647 Concomitant BRAF and PI3K/mTOR Blockade is Required for Effective Treatment of BRAFV600E Colon Cancer Gastroenterology. 142: S-129. DOI: 10.1016/S0016-5085(12)60487-9 |
0.389 |
|
| 2011 |
Roper J, Richardson MP, Wang WV, Richard LG, Chen W, Coffee EM, Sinnamon MJ, Lee L, Chen PC, Bronson RT, Martin ES, Hung KE. The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer. Plos One. 6: e25132. PMID 21966435 DOI: 10.1371/Journal.Pone.0025132 |
0.42 |
|
| 2011 |
Roper J, Richardson MP, Wang WV, Georgeon Richard L, Chen WY, Coffee EM, Lee L, Chen P, Bronson RT, Martin ES, Hung KE. The Dual PI3K/mTOR Inhibitor NVP-BEZ235 Induces Tumor Regression in a Genetically Engineered Mouse Model for Sporadic Colorectal Cancer Gastroenterology. 140: S-104-S-105. DOI: 10.1016/S0016-5085(11)60425-3 |
0.406 |
|
| 2010 |
Lee L, Richard LG, Richardson MP, Chen WY, Roper J, Martin ES, Hung KE. 177 A Novel Hybrid In Vitro – Orthotopic Transplant Model for Assessment of Experimental Colon Cancer Therapeutics Gastroenterology. 138: S-32. DOI: 10.1016/S0016-5085(10)60148-5 |
0.396 |
|
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