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Laura Ganser - Publications

Affiliations: 
Biochemistry Duke University, Durham, NC 
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19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Geng A, Ganser L, Roy R, Shi H, Pratihar S, Case DA, Al-Hashimi HM. An RNA excited conformational state at atomic resolution. Nature Communications. 14: 8432. PMID 38114465 DOI: 10.1038/s41467-023-43673-6  0.744
2023 Ganser LR, Niaki AG, Yuan X, Huang E, Deng D, Djaja NA, Ge Y, Craig A, Langlois O, Myong S. The roles of FUS-RNA binding domain and low complexity domain in RNA-dependent phase separation. Structure (London, England : 1993). PMID 38070499 DOI: 10.1016/j.str.2023.11.006  0.459
2023 Guo L, Mann JR, Mauna JC, Copley KE, Wang H, Rubien JD, Odeh HM, Lin J, Lee BL, Ganser L, Robinson E, Kim KM, Murthy AC, Paul T, Portz B, et al. Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains. Biorxiv : the Preprint Server For Biology. PMID 37732211 DOI: 10.1101/2023.09.04.555754  0.491
2023 Ken ML, Roy R, Geng A, Ganser LR, Manghrani A, Cullen BR, Schulze-Gahmen U, Herschlag D, Al-Hashimi HM. Author Correction: RNA conformational propensities determine cellular activity. Nature. PMID 37296211 DOI: 10.1038/s41586-023-06286-z  0.746
2023 Ken ML, Roy R, Geng A, Ganser LR, Manghrani A, Cullen BR, Schulze-Gahmen U, Herschlag D, Al-Hashimi HM. RNA conformational propensities determine cellular activity. Nature. PMID 37198487 DOI: 10.1038/s41586-023-06080-x  0.741
2022 Ganser LR, Ge Y, Myong S. Single-Molecule Fluorescence Methods to Study Protein-RNA Interactions Underlying Biomolecular Condensates. Methods in Molecular Biology (Clifton, N.J.). 2563: 149-160. PMID 36227472 DOI: 10.1007/978-1-0716-2663-4_7  0.434
2022 Rhine K, Dasovich M, Yoniles J, Badiee M, Skanchy S, Ganser LR, Ge Y, Fare CM, Shorter J, Leung AKL, Myong S. Poly(ADP-ribose) drives condensation of FUS via a transient interaction. Molecular Cell. PMID 35182479 DOI: 10.1016/j.molcel.2022.01.018  0.442
2020 Kelly ML, Chu CC, Shi H, Ganser LR, Bogerd HP, Huynh K, Hou Y, Cullen BR, Al-Hashimi HM. Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem-loop RNAs and their implications for functional cellular assays. Rna (New York, N.Y.). PMID 33028652 DOI: 10.1261/rna.076257.120  0.84
2020 Ganser LR, Lee J, Rangadurai A, Merriman DK, Kelly ML, Kansal AD, Sathyamoorthy B, Al-Hashimi HM. Publisher Correction: High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble. Nature Structural & Molecular Biology. PMID 32376863 DOI: 10.1038/S41594-020-0434-4  0.758
2020 Ganser LR, Chu CC, Bogerd HP, Kelly ML, Cullen BR, Al-Hashimi HM. Probing RNA Conformational Equilibria within the Functional Cellular Context. Cell Reports. 30: 2472-2480.e4. PMID 32101729 DOI: 10.1016/J.Celrep.2020.02.004  0.826
2019 Ganser LR, Kelly ML, Patwardhan NN, Hargrove AE, Al-Hashimi HM. Demonstration that small molecules can bind and stabilize low-abundance short-lived RNA excited conformational states. Journal of Molecular Biology. PMID 31863746 DOI: 10.1016/J.Jmb.2019.12.009  0.845
2019 Ganser LR, Kelly ML, Herschlag D, Al-Hashimi HM. The roles of structural dynamics in the cellular functions of RNAs. Nature Reviews. Molecular Cell Biology. PMID 31182864 DOI: 10.1038/S41580-019-0136-0  0.836
2018 Ganser LR, Lee J, Rangadurai A, Merriman DK, Kelly ML, Kansal AD, Sathyamoorthy B, Al-Hashimi HM. High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble. Nature Structural & Molecular Biology. 25: 425-434. PMID 29728655 DOI: 10.1038/S41594-018-0062-4  0.771
2017 Patwardhan NN, Ganser LR, Kapral GJ, Eubanks CS, Lee J, Sathyamoorthy B, Al-Hashimi HM, Hargrove AE. Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR. Medchemcomm. 8: 1022-1036. PMID 28798862 DOI: 10.1039/C6Md00729E  0.833
2017 Clay MC, Ganser LR, Merriman DK, Al-Hashimi HM. Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics. Nucleic Acids Research. PMID 28609788 DOI: 10.1093/Nar/Gkx525  0.838
2016 Ganser LR, Al-Hashimi HM. HIV-1 leader RNA dimeric interface revealed by NMR. Proceedings of the National Academy of Sciences of the United States of America. PMID 27837023 DOI: 10.1073/Pnas.1615789113  0.654
2014 Ganser LR, Mustoe AM, Al-Hashimi HM. An RNA tertiary switch by modifying how helices are tethered. Genome Biology. 15: 425. PMID 25315677 DOI: 10.1186/S13059-014-0425-Z  0.799
2014 Sathyamoorthy B, Lee J, Kimsey I, Ganser LR, Al-Hashimi H. Development and application of aromatic [(13)C, (1)H] SOFAST-HMQC NMR experiment for nucleic acids. Journal of Biomolecular Nmr. 60: 77-83. PMID 25186910 DOI: 10.1007/S10858-014-9856-9  0.737
2014 Sathyamoorthy B, Lee J, Kimsey I, Ganser LR, Al-Hashimi H. Development and application of aromatic [13C, 1H] SOFAST-HMQC NMR experiment for nucleic acids Journal of Biomolecular Nmr. DOI: 10.1007/s10858-014-9856-9  0.725
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