| Year |
Citation |
Score |
| 2023 |
Alshareef M, Hatchell D, Vasas T, Mallah K, Shingala A, Cutrone J, Alawieh A, Guo C, Tomlinson S, Eskandari R. Complement Drives Chronic Inflammation and Progressive Hydrocephalus in Murine Neonatal Germinal Matrix Hemorrhage. International Journal of Molecular Sciences. 24. PMID 37373319 DOI: 10.3390/ijms241210171 |
0.57 |
|
| 2023 |
Couch C, Alawieh AM, Toutonji A, Atkinson C, Tomlinson S. Evaluating the comorbidities of age and cigarette smoking on stroke outcomes in the context of anti-complement mitigation strategies. Frontiers in Immunology. 14: 1161051. PMID 37223091 DOI: 10.3389/fimmu.2023.1161051 |
0.549 |
|
| 2022 |
Alshareef M, Mallah K, Vasas T, Alawieh A, Borucki D, Couch C, Cutrone J, Shope C, Eskandari R, Tomlinson S. A Role of Complement in the Pathogenic Sequelae of Mouse Neonatal Germinal Matrix Hemorrhage. International Journal of Molecular Sciences. 23. PMID 35328364 DOI: 10.3390/ijms23062943 |
0.583 |
|
| 2021 |
Zheng C, Ricci J, Zhang Q, Alawieh A, Yang X, Nadig S, He S, Engel P, Jin J, Atkinson C, Tomlinson S. Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation. Frontiers in Immunology. 12: 785229. PMID 34899752 DOI: 10.3389/fimmu.2021.785229 |
0.612 |
|
| 2021 |
Yarmoska SK, Alawieh AM, Tomlinson S, Hoang KB. Modulation of the Complement System by Neoplastic Disease of the Central Nervous System. Frontiers in Immunology. 12: 689435. PMID 34671342 DOI: 10.3389/fimmu.2021.689435 |
0.523 |
|
| 2021 |
Mallah K, Couch C, Alshareef M, Borucki D, Yang X, Alawieh A, Tomlinson S. Complement mediates neuroinflammation and cognitive decline at extended chronic time points after traumatic brain injury. Acta Neuropathologica Communications. 9: 72. PMID 33879257 DOI: 10.1186/s40478-021-01179-6 |
0.583 |
|
| 2021 |
Annamalai B, Parsons N, Nicholson C, Joseph K, Coughlin B, Yang X, Jones BW, Tomlinson S, Rohrer B. Natural immunoglobulin M-based delivery of a complement alternative pathway inhibitor in mouse models of retinal degeneration. Experimental Eye Research. 108583. PMID 33878326 DOI: 10.1016/j.exer.2021.108583 |
0.604 |
|
| 2021 |
Alawieh A, Chalhoub R, Mallah K, Langley EF, York M, Broome H, Couch C, Adkins D, Tomlinson S. Complement Drives Synaptic Degeneration and Progressive Cognitive Decline in the Chronic Phase After Traumatic Brain Injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33446516 DOI: 10.1523/JNEUROSCI.1734-20.2020 |
0.738 |
|
| 2020 |
Li C, Patel K, Tu Z, Yang X, Kulik L, Alawieh A, Allen P, Cheng Q, Wallace C, Kilkenny J, Kwon J, Gibney B, Cantu E, Sharma A, Pipkin M, ... ... Tomlinson S, et al. A novel injury site-natural antibody targeted complement inhibitor protects against lung transplant injury. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 33210808 DOI: 10.1111/ajt.16404 |
0.606 |
|
| 2020 |
Mallah K, Couch C, Borucki DM, Toutonji A, Alshareef M, Tomlinson S. Anti-inflammatory and Neuroprotective Agents in Clinical Trials for CNS Disease and Injury: Where Do We Go From Here? Frontiers in Immunology. 11: 2021. PMID 33013859 DOI: 10.3389/Fimmu.2020.02021 |
0.398 |
|
| 2020 |
Alawieh A, Langley EF, Feng WW, Spiotta A, Tomlinson S. Complement-dependent synaptic uptake and cognitive decline after stroke and reperfusion therapy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32291326 DOI: 10.1523/Jneurosci.2462-19.2020 |
0.634 |
|
| 2020 |
Nguyen H, Alawieh A, Bastian D, Kuril S, Dai M, Daenthanasanmak A, Zhang M, Iamsawat S, Schutt SD, Wu Y, Sleiman MM, Shetty A, Atkinson C, Sun S, Varela JC, ... Tomlinson S, et al. Targeting the Complement Alternative Pathway Permits Graft Versus Leukemia Activity while Preventing Graft Versus Host Disease. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31919135 DOI: 10.1158/1078-0432.Ccr-19-1717 |
0.575 |
|
| 2020 |
McQuiston A, Li C, Patel K, Tu Z, Cheng Q, Tomlinson S, Atkinson C. A NOVEL INJURY SITE-NATURAL ANTIBODY TARGETED COMPLEMENT INHIBITOR PROTECTS AGAINST LUNG TRANSPLANT AUTOANTIBODY EXACERBATED ISCHEMIA REPERFUSION INJURY Transplantation. 104: S4-S4. DOI: 10.1097/01.Tp.0000698272.18648.Cb |
0.376 |
|
| 2019 |
Zhong F, Hu Z, Jiang K, Lei B, Wu Z, Yuan G, Luo H, Dong C, Tang B, Zheng C, Yang S, Zeng Y, Guo Z, Yu S, Su H, ... ... Tomlinson S, et al. Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis. Cell Research. PMID 31076642 DOI: 10.1038/S41422-019-0175-2 |
0.356 |
|
| 2019 |
Parsons N, Annamalai B, Obert E, Schnabolk G, Tomlinson S, Rohrer B. Inhibition of the alternative complement pathway accelerates repair processes in the murine model of choroidal neovascularization. Molecular Immunology. 108: 8-12. PMID 30763805 DOI: 10.1016/J.Molimm.2019.02.001 |
0.638 |
|
| 2019 |
Novgorodov SA, Voltin JR, Wang W, Tomlinson S, Riley CL, Gudz TI. Acid sphingomyelinase deficiency protects mitochondria and improves function recovery after brain injury. Journal of Lipid Research. PMID 30662008 DOI: 10.1194/Jlr.M091132 |
0.331 |
|
| 2019 |
Li C, Patel K, Allen P, TU Z, Kilkenny J, Wallace C, Nadig S, Tomlinson S, Atkinson C. A Novel Injury Site-Targeted Complement Inhibitor Which Protects against Lung Transplant Ischemia Reperfusion Injury The Journal of Heart and Lung Transplantation. 38: S13. DOI: 10.1016/J.Healun.2019.01.016 |
0.376 |
|
| 2018 |
Nguyen H, Kuril S, Bastian D, Kim J, Zhang M, Vaena SG, Dany M, Dai M, Heinrichs JL, Daenthanasanmak A, Iamsawat S, Schutt S, Fu J, Wu Y, Fairlie DP, ... ... Tomlinson S, et al. Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells. Jci Insight. 3. PMID 30568037 DOI: 10.1172/Jci.Insight.121697 |
0.318 |
|
| 2018 |
Scholpa NE, Williams H, Wang W, Corum D, Narang A, Tomlinson S, Sulllivan PG, Rabchevsky AG, Schnellmann RG. Pharmacological stimulation of mitochondrial biogenesis using the FDA-approved β2-adrenoreceptor agonist formoterol for the treatment of spinal cord injury. Journal of Neurotrauma. PMID 30280980 DOI: 10.1089/Neu.2018.5669 |
0.343 |
|
| 2018 |
Tomlinson S, Thurman JM. Tissue-targeted complement therapeutics. Molecular Immunology. 102: 120-128. PMID 30220307 DOI: 10.1016/J.Molimm.2018.06.005 |
0.32 |
|
| 2018 |
Bosco A, Anderson SR, Breen KT, Romero CO, Steele MR, Chiodo VA, Boye SL, Hauswirth WW, Tomlinson S, Vetter ML. Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30217731 DOI: 10.1016/J.Ymthe.2018.08.017 |
0.378 |
|
| 2018 |
Alawieh A, Andersen M, Adkins DL, Tomlinson S. Acute Complement inhibition potentiates neurorehabilitation and enhances tPA-mediated neuroprotection. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29921716 DOI: 10.1523/Jneurosci.0111-18.2018 |
0.766 |
|
| 2018 |
Mulligan JK, Patel K, Williamson T, Reaves N, Carroll W, Stephenson SE, Gao P, Drake RR, Neely BA, Tomlinson S, Schlosser RJ, Atkinson C. C3a receptor antagonism as a novel therapeutic target for chronic rhinosinusitis. Mucosal Immunology. PMID 29907871 DOI: 10.1038/S41385-018-0048-X |
0.34 |
|
| 2018 |
Alawieh A, Langley EF, Tomlinson S. Targeted complement inhibition salvages stressed neurons and inhibits neuroinflammation after stroke in mice. Science Translational Medicine. 10. PMID 29769288 DOI: 10.1126/Scitranslmed.Aao6459 |
0.626 |
|
| 2018 |
Alawieh A, Langley EF, Weber S, Adkins D, Tomlinson S. Identifying the role of complement in triggering neuroinflammation after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29437855 DOI: 10.1523/Jneurosci.2197-17.2018 |
0.776 |
|
| 2018 |
Schnabolk G, Parsons N, Obert E, Annamalai B, Nasarre C, Tomlinson S, Lewin AS, Rohrer B. Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization. Molecular Therapy. Methods & Clinical Development. 9: 1-11. PMID 29234687 DOI: 10.1016/J.Omtm.2017.11.003 |
0.633 |
|
| 2018 |
Langley F, Alawieh A, Tomlinson S. Abstract 176: Enhancing the Efficacy of Current Management of Ischemic Stroke Using Injury-Site Targeted Complement Inhibition - A Preclinical Study Stroke. 49. DOI: 10.1161/str.49.suppl_1.176 |
0.591 |
|
| 2018 |
Toutonji A, Sleiman M, Zhang Q, Tu Z, Li C, Kulik L, Holers M, Atkinson C, Tomlinson S. A novel injury site-targeted complement inhibitor: Applications in ischemia reperfusion injury Molecular Immunology. 102: 222. DOI: 10.1016/J.Molimm.2018.06.231 |
0.369 |
|
| 2018 |
Sleiman M, Lei B, Cheng Q, Tomlinson S, Atkinson C. Perfusion of vascularized composite allografts with a complement inhibitor protects against brain death induced injury and IRI Molecular Immunology. 102: 221. DOI: 10.1016/J.Molimm.2018.06.229 |
0.336 |
|
| 2018 |
Alawieh A, Langley EF, York M, Broome H, Adkins D, Tomlinson S. It is never too late–reversing cognitive deficits in chronic traumatic brain injury with local complement modulation Molecular Immunology. 102: 179. DOI: 10.1016/J.Molimm.2018.06.134 |
0.736 |
|
| 2018 |
Banda NK, Ramirez JR, Yang X, Khan N, Wang G, Simberg D, Kulik L, Tomlinson S, Holers VM. Recombinant single chain antibody-fused complement inhibitor locally target and attenuates arthritis in mice Molecular Immunology. 102: 133-134. DOI: 10.1016/J.Molimm.2018.06.028 |
0.311 |
|
| 2018 |
Alawieh A, Langley EF, Tomlinson S. Targeting an immune injury-sensing mechanism after stroke to salvage neurons marked for destruction by complement opsonization Molecular Immunology. 102: 130. DOI: 10.1016/J.Molimm.2018.06.019 |
0.621 |
|
| 2017 |
Marshall K, Jin J, Atkinson C, Alawieh A, Qiao F, Lei B, Chavin KD, He S, Tomlinson S. Natural IgM initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration. Hepatology (Baltimore, Md.). PMID 28880403 DOI: 10.1002/Hep.29512 |
0.6 |
|
| 2017 |
Alawieh A, Tomlinson S, Adkins D, Kautz S, Feng W. Preclinical and Clinical Evidence on Ipsilateral Corticospinal Projections: Implication for Motor Recovery. Translational Stroke Research. PMID 28691140 DOI: 10.1007/S12975-017-0551-5 |
0.73 |
|
| 2017 |
Narang A, Qiao F, Atkinson C, Zhu H, Yang X, Kulik L, Holers VM, Tomlinson S. Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement. Journal of Neuroinflammation. 14: 120. PMID 28629465 DOI: 10.1186/S12974-017-0894-6 |
0.36 |
|
| 2017 |
Schnabolk G, Beon MK, Tomlinson S, Rohrer B. New Insights on Complement Inhibitor CD59 in Mouse Laser-Induced Choroidal Neovascularization: Mislocalization After Injury and Targeted Delivery for Protein Replacement. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 28333572 DOI: 10.1089/jop.2016.0101 |
0.58 |
|
| 2017 |
Vetter M, Bosco A, Anderson S, Breen K, Romero C, Steele M, Chiodo V, Boye S, Hauswirth W, Tomlinson S. Contribution of microglia and complement activation to glaucoma progression Acta Ophthalmologica. 95. DOI: 10.1111/J.1755-3768.2017.03621 |
0.303 |
|
| 2017 |
Rohrer B, Schnabolk G, Annamalei B, Parsons N, Potts J, Lewin A, Tomlinson SM. Delivery of CR2-fH using AAV vector therapy and encapsulated cell technology as treatment strategies in mouse model of neovascularization Molecular Immunology. 89: 202. DOI: 10.1016/J.Molimm.2017.06.230 |
0.556 |
|
| 2016 |
Zhu P, Bailey SR, Lei B, Paulos CM, Atkinson C, Tomlinson S. Targeted complement inhibition protects vascularized composite allografts from acute graft injury and prolongs graft survival when combined with subtherapeutic cyclosporine A therapy. Transplantation. PMID 28045880 DOI: 10.1097/Tp.0000000000001625 |
0.327 |
|
| 2016 |
Alawieh A, Tomlinson S. Injury site-specific targeting of complement inhibitors for treating stroke. Immunological Reviews. 274: 270-280. PMID 27782326 DOI: 10.1111/Imr.12470 |
0.67 |
|
| 2016 |
Alawieh A, Wang W, Narang A, Tomlinson S. Thromboembolic Model of Cerebral Ischemia and Reperfusion in Mice. Methods in Molecular Biology (Clifton, N.J.). 1462: 357-72. PMID 27604728 DOI: 10.1007/978-1-4939-3816-2_20 |
0.59 |
|
| 2016 |
Holers VM, Tomlinson S, Kulik L, Atkinson C, Rohrer B, Banda N, Thurman JM. New therapeutic and diagnostic opportunities for injured tissue-specific targeting of complement inhibitors and imaging modalities. Seminars in Immunology. PMID 27282113 DOI: 10.1016/J.Smim.2016.05.007 |
0.652 |
|
| 2016 |
Woodell A, Jones BW, Williamson T, Schnabolk G, Tomlinson S, Atkinson C, Rohrer B. A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury. Investigative Ophthalmology & Visual Science. 57: 1728-37. PMID 27064393 DOI: 10.1167/Iovs.15-18471 |
0.618 |
|
| 2016 |
Nguyen HD, Alawieh A, Bastian DA, Daenthanasanmak A, Schutt SD, Iamsawat S, Wu Y, Carl A, Tomlinson S, Yu X. Inhibition of Alternative Complement Pathway in Target Organs Represents a Novel and Effective Approach to Control Gvhd While Sparing GVL Effect Blood. 128: 807-807. DOI: 10.1182/Blood.V128.22.807.807 |
0.635 |
|
| 2015 |
Alawieh A, Elvington A, Zhu H, Yu J, Kindy MS, Atkinson C, Tomlinson S. Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement. Journal of Neuroinflammation. 12: 247. PMID 26714866 DOI: 10.1186/S12974-015-0464-8 |
0.648 |
|
| 2015 |
Alawieh A, Elvington A, Tomlinson S. Complement in the Homeostatic and Ischemic Brain. Frontiers in Immunology. 6: 417. PMID 26322048 DOI: 10.3389/Fimmu.2015.00417 |
0.644 |
|
| 2015 |
Alawieh A, Narang A, Tomlinson S. Complementing regeneration. Oncotarget. 6: 21769-70. PMID 26318041 DOI: 10.18632/oncotarget.4844 |
0.508 |
|
| 2015 |
Alawieh A, Sabra Z, Sabra M, Tomlinson S, Zaraket FA. A Rich-Club Organization in Brain Ischemia Protein Interaction Network. Scientific Reports. 5: 13513. PMID 26310627 DOI: 10.1038/Srep13513 |
0.621 |
|
| 2015 |
Alawieh A, Sabra M, Sabra Z, Tomlinson S, Zaraket FA. Molecular Architecture of Spinal Cord Injury Protein Interaction Network. Plos One. 10: e0135024. PMID 26241741 DOI: 10.1371/Journal.Pone.0135024 |
0.61 |
|
| 2015 |
Varela JC, Tomlinson S. Complement: an overview for the clinician. Hematology/Oncology Clinics of North America. 29: 409-27. PMID 26043382 DOI: 10.1016/J.Hoc.2015.02.001 |
0.364 |
|
| 2015 |
Atkinson C, Qiao F, Yang X, Zhu P, Reaves N, Kulik L, Goddard M, Holers VM, Tomlinson S. Targeting pathogenic postischemic self-recognition by natural IgM to protect against posttransplantation cardiac reperfusion injury. Circulation. 131: 1171-80. PMID 25825397 DOI: 10.1161/Circulationaha.114.010482 |
0.384 |
|
| 2015 |
Kulik L, Hewitt FB, Willis VC, Rodriguez R, Tomlinson S, Holers VM. A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease. Molecular Immunology. 63: 479-88. PMID 25457881 DOI: 10.1016/J.Molimm.2014.10.005 |
0.336 |
|
| 2015 |
Nguyen H, Heinrichs JL, Fu J, Wu Y, Bastian D, Schutt S, Daenthanasanmak A, Dany M, Liu C, Fairlie D, Tomlinson S, Yu X. Targeting Host Complement C3a/C5a Receptors to Control of Acute Graft-Versus-Host Disease in Mice Blood. 126: 3076-3076. DOI: 10.1182/Blood.V126.23.3076.3076 |
0.332 |
|
| 2015 |
Elvington M, Schepp-Berglind J, Tomlinson S. Regulation of the alternative pathway of complement modulates injury and immunity in a chronic model of dextran sulphate sodium-induced colitis Clinical and Experimental Immunology. 179: 500-508. DOI: 10.1111/Cei.12464 |
0.437 |
|
| 2014 |
Marshall KM, He S, Zhong Z, Atkinson C, Tomlinson S. Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy. The Journal of Experimental Medicine. 211: 1793-805. PMID 25113972 DOI: 10.1084/Jem.20131902 |
0.385 |
|
| 2014 |
Elvington M, Scheiber M, Yang X, Lyons K, Jacqmin D, Wadsworth C, Marshall D, Vanek K, Tomlinson S. Complement-dependent modulation of antitumor immunity following radiation therapy. Cell Reports. 8: 818-30. PMID 25066124 DOI: 10.1016/J.Celrep.2014.06.051 |
0.341 |
|
| 2014 |
Elvington M, Blichmann P, Qiao F, Scheiber M, Wadsworth C, Luzinov I, Lucero J, Vertegel A, Tomlinson S. A novel protocol allowing oral delivery of a protein complement inhibitor that subsequently targets to inflamed colon mucosa and ameliorates murine colitis. Clinical and Experimental Immunology. 177: 500-8. PMID 24730624 DOI: 10.1111/Cei.12350 |
0.372 |
|
| 2014 |
Liu F, Wu L, Wu G, Wang C, Zhang L, Tomlinson S, Qin X. Targeted mouse complement inhibitor CR2-Crry protects against the development of atherosclerosis in mice. Atherosclerosis. 234: 237-43. PMID 24685815 DOI: 10.1016/J.Atherosclerosis.2014.03.004 |
0.409 |
|
| 2014 |
Schnabolk G, Tomlinson S, Rohrer B. The complement regulatory protein CD59: insights into attenuation of choroidal neovascularization. Advances in Experimental Medicine and Biology. 801: 435-40. PMID 24664728 DOI: 10.1007/978-1-4614-3209-8_55 |
0.628 |
|
| 2014 |
Di Paolo NC, Baldwin LK, Irons EE, Papayannopoulou T, Tomlinson S, Shayakhmetov DM. IL-1α and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cells. Plos Pathogens. 10: e1004035. PMID 24651866 DOI: 10.1371/Journal.Ppat.1004035 |
0.321 |
|
| 2013 |
Khan MA, Maasch C, Vater A, Klussmann S, Morser J, Leung LL, Atkinson C, Tomlinson S, Heeger PS, Nicolls MR. Targeting complement component 5a promotes vascular integrity and limits airway remodeling. Proceedings of the National Academy of Sciences of the United States of America. 110: 6061-6. PMID 23530212 DOI: 10.1073/Pnas.1217991110 |
0.351 |
|
| 2013 |
Sun S, Zhao G, Liu C, Wu X, Guo Y, Yu H, Song H, Du L, Jiang S, Guo R, Tomlinson S, Zhou Y. Inhibition of complement activation alleviates acute lung injury induced by highly pathogenic avian influenza H5N1 virus infection. American Journal of Respiratory Cell and Molecular Biology. 49: 221-30. PMID 23526211 DOI: 10.1165/Rcmb.2012-0428Oc |
0.34 |
|
| 2013 |
Atkinson C, Floerchinger B, Qiao F, Casey S, Williamson T, Moseley E, Stoica S, Goddard M, Ge X, Tullius SG, Tomlinson S. Donor brain death exacerbates complement-dependent ischemia/reperfusion injury in transplanted hearts. Circulation. 127: 1290-9. PMID 23443736 DOI: 10.1161/Circulationaha.112.000784 |
0.34 |
|
| 2013 |
Holers VM, Rohrer B, Tomlinson S. CR2-mediated targeting of complement inhibitors: bench-to-bedside using a novel strategy for site-specific complement modulation. Advances in Experimental Medicine and Biology. 735: 137-54. PMID 23402024 DOI: 10.1007/978-1-4614-4118-2_9 |
0.67 |
|
| 2012 |
Qiu S, Liu N, Jia L, Yang G, Su W, Li J, Song L, Yang C, Wang J, Zhang C, Wang Z, Qiao F, Tomlinson S, Atkinson C, Sun Y, et al. A new treatment for neurogenic inflammation caused by EV71 with CR2-targeted complement inhibitor. Virology Journal. 9: 285. PMID 23173749 DOI: 10.1186/1743-422X-9-285 |
0.304 |
|
| 2012 |
Hu X, Tomlinson S, Barnum SR. Targeted inhibition of complement using complement receptor 2-conjugated inhibitors attenuates EAE. Neuroscience Letters. 531: 35-9. PMID 23079547 DOI: 10.1016/J.Neulet.2012.10.012 |
0.357 |
|
| 2012 |
Elvington A, Atkinson C, Zhu H, Yu J, Takahashi K, Stahl GL, Kindy MS, Tomlinson S. The alternative complement pathway propagates inflammation and injury in murine ischemic stroke. Journal of Immunology (Baltimore, Md. : 1950). 189: 4640-7. PMID 23028050 DOI: 10.4049/Jimmunol.1201904 |
0.422 |
|
| 2012 |
Ramos TN, Darley MM, Weckbach S, Stahel PF, Tomlinson S, Barnum SR. The C5 convertase is not required for activation of the terminal complement pathway in murine experimental cerebral malaria. The Journal of Biological Chemistry. 287: 24734-8. PMID 22689574 DOI: 10.1074/Jbc.C112.378364 |
0.317 |
|
| 2012 |
Schepp-Berglind J, Atkinson C, Elvington M, Qiao F, Mannon P, Tomlinson S. Complement-dependent injury and protection in a murine model of acute dextran sulfate sodium-induced colitis. Journal of Immunology (Baltimore, Md. : 1950). 188: 6309-18. PMID 22566568 DOI: 10.4049/Jimmunol.1200553 |
0.4 |
|
| 2012 |
Elvington M, Huang Y, Morgan BP, Qiao F, van Rooijen N, Atkinson C, Tomlinson S. A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer. Blood. 119: 6043-51. PMID 22442351 DOI: 10.1182/Blood-2011-10-383232 |
0.371 |
|
| 2012 |
Elvington A, Atkinson C, Kulik L, Zhu H, Yu J, Kindy MS, Holers VM, Tomlinson S. Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice. Journal of Immunology (Baltimore, Md. : 1950). 188: 1460-8. PMID 22198950 DOI: 10.4049/Jimmunol.1102132 |
0.403 |
|
| 2012 |
Takeda K, Thurman JM, Tomlinson S, Okamoto M, Shiraishi Y, Ferreira VP, Cortes C, Pangburn MK, Holers VM, Gelfand EW. The critical role of complement alternative pathway regulator factor H in allergen-induced airway hyperresponsiveness and inflammation. Journal of Immunology (Baltimore, Md. : 1950). 188: 661-7. PMID 22174452 DOI: 10.4049/Jimmunol.1101813 |
0.349 |
|
| 2011 |
Sun S, Guo Y, Zhao G, Zhou X, Li J, Hu J, Yu H, Chen Y, Song H, Qiao F, Xu G, Yang F, Wu Y, Tomlinson S, Duan Z, et al. Complement and the alternative pathway play an important role in LPS/D-GalN-induced fulminant hepatic failure. Plos One. 6: e26838. PMID 22069473 DOI: 10.1371/Journal.Pone.0026838 |
0.327 |
|
| 2011 |
Sekine H, Ruiz P, Gilkeson GS, Tomlinson S. The dual role of complement in the progression of renal disease in NZB/W F(1) mice and alternative pathway inhibition. Molecular Immunology. 49: 317-23. PMID 22000720 DOI: 10.1016/J.Molimm.2011.09.015 |
0.393 |
|
| 2011 |
Khan MA, Jiang X, Dhillon G, Beilke J, Holers VM, Atkinson C, Tomlinson S, Nicolls MR. CD4+ T cells and complement independently mediate graft ischemia in the rejection of mouse orthotopic tracheal transplants. Circulation Research. 109: 1290-301. PMID 21998328 DOI: 10.1161/Circresaha.111.250167 |
0.362 |
|
| 2011 |
Renner B, Ferreira VP, Cortes C, Goldberg R, Ljubanovic D, Pangburn MK, Pickering MC, Tomlinson S, Holland-Neidermyer A, Strassheim D, Holers VM, Thurman JM. Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury. Kidney International. 80: 165-73. PMID 21544060 DOI: 10.1038/Ki.2011.115 |
0.369 |
|
| 2011 |
Sekine H, Kinser TT, Qiao F, Martinez E, Paulling E, Ruiz P, Gilkeson GS, Tomlinson S. The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice. Arthritis and Rheumatism. 63: 1076-85. PMID 21452327 DOI: 10.1002/Art.30222 |
0.348 |
|
| 2011 |
Sun S, Wang H, Zhao G, An Y, Guo Y, Du L, Song H, Qiao F, Yu H, Wu X, Atkinson C, Jiang S, Tomlinson S, Zhou Y. Complement inhibition alleviates paraquat-induced acute lung injury. American Journal of Respiratory Cell and Molecular Biology. 45: 834-42. PMID 21421909 DOI: 10.1165/Rcmb.2010-0444Oc |
0.367 |
|
| 2011 |
Rohrer B, Coughlin B, Kunchithapautham K, Long Q, Tomlinson S, Takahashi K, Holers VM. The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization. Molecular Immunology. 48: e1-8. PMID 21257205 DOI: 10.1016/J.Molimm.2010.12.016 |
0.631 |
|
| 2011 |
Qing X, Redecha PB, Burmeister MA, Tomlinson S, D'Agati VD, Davisson RL, Salmon JE. Targeted inhibition of complement activation prevents features of preeclampsia in mice. Kidney International. 79: 331-9. PMID 20944547 DOI: 10.1038/Ki.2010.393 |
0.322 |
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| 2011 |
Hylton DJ, Hoffman SM, Van Rooijen N, Tomlinson S, Fleming SD. Macrophage-produced IL-12p70 mediates hemorrhage-induced damage in a complement-dependent manner. Shock (Augusta, Ga.). 35: 134-40. PMID 20577145 DOI: 10.1097/Shk.0B013E3181Ed8Ec9 |
0.323 |
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| 2011 |
Schepp-Berglind J, Atkinson C, Tomlinson S. Complement-dependent injury versus protection in a murine model of DSS-induced colitis Inflammatory Bowel Diseases. 17: S81. DOI: 10.1097/00054725-201112002-00268 |
0.358 |
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| 2011 |
Khan M, Jiang X, Atkinson C, Tomlinson S, Nicolls M. 379 The Role of C3 Activation in Airway Hypoxia and Ischemia in Murine Model of Orthotopic Tracheal Transplantation The Journal of Heart and Lung Transplantation. 30: S130-S131. DOI: 10.1016/J.Healun.2011.01.387 |
0.305 |
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| 2010 |
Atkinson C, He S, Morris K, Qiao F, Casey S, Goddard M, Tomlinson S. Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation. Journal of Immunology (Baltimore, Md. : 1950). 185: 7007-13. PMID 20962256 DOI: 10.4049/Jimmunol.1001504 |
0.4 |
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| 2010 |
Qiao F, Atkinson C, Kindy MS, Shunmugavel A, Morgan BP, Song H, Tomlinson S. The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury. The American Journal of Pathology. 177: 3061-70. PMID 20952585 DOI: 10.2353/ajpath.2010.100158 |
0.416 |
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| 2010 |
Pope MR, Hoffman SM, Tomlinson S, Fleming SD. Complement regulates TLR4-mediated inflammatory responses during intestinal ischemia reperfusion. Molecular Immunology. 48: 356-64. PMID 20800895 DOI: 10.1016/J.Molimm.2010.07.004 |
0.331 |
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| 2010 |
Rohrer B, Long Q, Coughlin B, Renner B, Huang Y, Kunchithapautham K, Ferreira VP, Pangburn MK, Gilkeson GS, Thurman JM, Tomlinson S, Holers VM. A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration. Advances in Experimental Medicine and Biology. 703: 137-49. PMID 20711712 DOI: 10.1007/978-1-4419-5635-4_10 |
0.658 |
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| 2010 |
Fleming SD, Hylton D, Hoffman S, Pope M, Tomlinson S. CR2 targeted complement inhibitors attenuate intestinal damage Molecular Immunology. 47: 2277-2277. DOI: 10.1016/J.Molimm.2010.05.236 |
0.317 |
|
| 2010 |
Gelber SE, Redecha PB, Tomlinson S, Davisson RL, Salmon JE. Inhibition of complement activation prevents features of preeclampsia in a mouse model Molecular Immunology. 47: 2276-2276. DOI: 10.1016/J.Molimm.2010.05.233 |
0.303 |
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| 2010 |
Atkinson C, Yang X, Kulik L, Qiao F, Casey S, Holers VM, Tomlinson S. Targeting complement inhibition to post-ischemic neoepitopes exposed in transplanted hearts Molecular Immunology. 47: 2266-2266. DOI: 10.1016/J.Molimm.2010.05.205 |
0.307 |
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| 2010 |
He S, Atkinson C, Morris K, Kulik L, Holers VM, Tomlinson S. Pathogenic natural IgM antibodies recognizing vascular post-ischemic neoepitopes initiate the inflammatory response important for both hepatic ischemia/reperfusion injury and liver regeneration Molecular Immunology. 47: 2266-2266. DOI: 10.1016/J.Molimm.2010.05.204 |
0.35 |
|
| 2010 |
Morris K, He S, Atkinson C, Morgan BP, Tomlinson S. The terminal pathway of complement in hepatic ischemia/reperfusion injury and regeneration Molecular Immunology. 47: 2209-2209. DOI: 10.1016/J.Molimm.2010.05.044 |
0.347 |
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| 2010 |
Atkinson C, He S, Morris K, Casey S, Goddard M, Tomlinson S. Targeted complement inhibition significantly ameliorates ischemia reperfusion induced isograft inflammation in a murine model of cardiac transplantation Molecular Immunology. 47: 2202-2203. DOI: 10.1016/J.Molimm.2010.05.026 |
0.329 |
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| 2010 |
Elvington A, Atkinson C, Kulik L, Zhu H, Yu J, Kindy MS, Morgan BP, Holers VM, Tomlinson S. Complement activation and cerebral injury following ischemic stroke Molecular Immunology. 47: 2198-2198. DOI: 10.1016/J.Molimm.2010.05.014 |
0.358 |
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| 2009 |
Banda NK, Levitt B, Glogowska MJ, Thurman JM, Takahashi K, Stahl GL, Tomlinson S, Arend WP, Holers VM. Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice. Journal of Immunology (Baltimore, Md. : 1950). 183: 5928-37. PMID 19828624 DOI: 10.4049/Jimmunol.0901826 |
0.352 |
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| 2009 |
Atkinson C, Varela JC, Tomlinson S. Complement-dependent inflammation and injury in a murine model of brain dead donor hearts. Circulation Research. 105: 1094-101. PMID 19815824 DOI: 10.1161/Circresaha.109.194977 |
0.318 |
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| 2009 |
He S, Atkinson C, Evans Z, Ellett JD, Southwood M, Elvington A, Chavin KD, Tomlinson S. A role for complement in the enhanced susceptibility of steatotic livers to ischemia and reperfusion injury. Journal of Immunology (Baltimore, Md. : 1950). 183: 4764-72. PMID 19752222 DOI: 10.4049/Jimmunol.0900550 |
0.338 |
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| 2009 |
He S, Atkinson C, Qiao F, Cianflone K, Chen X, Tomlinson S. A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice. The Journal of Clinical Investigation. 119: 2304-16. PMID 19620784 DOI: 10.1172/Jci38289 |
0.376 |
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| 2009 |
Thurman JM, Renner B, Kunchithapautham K, Ferreira VP, Pangburn MK, Ablonczy Z, Tomlinson S, Holers VM, Rohrer B. Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury. The Journal of Biological Chemistry. 284: 16939-47. PMID 19386604 DOI: 10.1074/Jbc.M808166200 |
0.629 |
|
| 2009 |
Rohrer B, Long Q, Coughlin B, Wilson RB, Huang Y, Qiao F, Tang PH, Kunchithapautham K, Gilkeson GS, Tomlinson S. A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration. Investigative Ophthalmology & Visual Science. 50: 3056-64. PMID 19264882 DOI: 10.1167/Iovs.08-2222 |
0.642 |
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| 2009 |
Stano P, Williams V, Villani M, Cymbalyuk ES, Qureshi A, Huang Y, Morace G, Luberto C, Tomlinson S, Del Poeta M. App1: an antiphagocytic protein that binds to complement receptors 3 and 2. Journal of Immunology (Baltimore, Md. : 1950). 182: 84-91. PMID 19109138 DOI: 10.4049/Jimmunol.182.1.84 |
0.319 |
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| 2009 |
Schepp J, Atkinson C, Qiao F, Spearman J, Gilkeson G, Tomlinson S. Role of complement and the use of complement Inhibitors in the Acute DSS Model of IBD Inflammatory Bowel Diseases. 15: S31. DOI: 10.1097/00054725-200912002-00090 |
0.307 |
|
| 2009 |
Banda NK, Levitt B, Glogowska MJ, Thurman JM, Takahashi K, Stahl GL, Tomlinson S, Arend WP, Holers VM. Targeted inhibition of the alternative pathway of complement with complement receptor 2-factor H protein attenuates collagen antibody-induced arthritis in mice Molecular Immunology. 46: 2844. DOI: 10.1016/J.Molimm.2009.05.256 |
0.335 |
|
| 2009 |
Huang Y, Qiao F, Atkinson C, Holers VM, Tomlinson S. A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury Journal of Immunology. 181: 8068-8076. |
0.311 |
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| 2008 |
Huang Y, Qiao F, Atkinson C, Holers VM, Tomlinson S. A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury. Journal of Immunology (Baltimore, Md. : 1950). 181: 8068-76. PMID 19017999 DOI: 10.4049/Jimmunol.181.11.8068 |
0.424 |
|
| 2008 |
Varela JC, Imai M, Atkinson C, Ohta R, Rapisardo M, Tomlinson S. Modulation of protective T cell immunity by complement inhibitor expression on tumor cells. Cancer Research. 68: 6734-42. PMID 18701498 DOI: 10.1158/0008-5472.Can-08-0502 |
0.323 |
|
| 2008 |
Hwang HY, Duvall MR, Tomlinson S, Boackle RJ. Highly specific inhibition of C1q globular-head binding to human IgG: a novel approach to control and regulate the classical complement pathway using an engineered single chain antibody variable fragment. Molecular Immunology. 45: 2570-80. PMID 18313756 DOI: 10.1016/J.Molimm.2007.12.019 |
0.329 |
|
| 2008 |
Rohrer B, Long Q, Wilson B, Coughlin B, Huang Y, Qiao F, Tang P, Kunchithapautham K, Gilkeson G, Tomlinson S. Alternative complement pathway signalling in a mouse model of choroidal neovascularisation Molecular Immunology. 45: 4162. DOI: 10.1016/J.Molimm.2008.08.201 |
0.584 |
|
| 2008 |
Rohrer B, Renner B, Kunchithapautham K, Ablonczy Z, Tomlinson S, Thurman J. Oxidative stress renders retinal epithelial cells susceptible to complement mediated injury Molecular Immunology. 45: 4162. DOI: 10.1016/J.Molimm.2008.08.200 |
0.609 |
|
| 2008 |
Atkinson C, Gong Y, Huang Y, Pauling E, Goddard M, Tomlinson S. The role of complement in myocardial ischaemia/reperfusion injury and antibody-mediated rejection in a mouse heterotopic heart transplant model Molecular Immunology. 45: 4160-4161. DOI: 10.1016/J.Molimm.2008.08.195 |
0.339 |
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| 2008 |
Huang Y, Qiao F, Atkinson C, Thurman J, Holers M, Tomlinson S. Targeted inhibitors of the alternative pathway and therapeutic characterization in models of intestine and cerebral ischaemia/reperfusion injury Molecular Immunology. 45: 4155-4156. DOI: 10.1016/J.Molimm.2008.08.180 |
0.382 |
|
| 2008 |
Sekine H, Gilkeson G, Tomlinson S. Targeted inhibition of the alternative pathway by CR2-fH fusion protein ameliorates progression of renal disease in MRL/lpr mice Molecular Immunology. 45: 4153. DOI: 10.1016/J.Molimm.2008.08.173 |
0.323 |
|
| 2008 |
Thurman J, Takeda K, Tomlinson S, Gelfand E, Holers M. Targeted complement-inhibitory proteins CR2-Crry and CR2-fH ameliorate allergen-induced airway hyperresponsiveness and inflammation Molecular Immunology. 45: 4152. DOI: 10.1016/J.Molimm.2008.08.170 |
0.31 |
|
| 2007 |
Song H, Qiao F, Atkinson C, Holers VM, Tomlinson S. A complement C3 inhibitor specifically targeted to sites of complement activation effectively ameliorates collagen-induced arthritis in DBA/1J mice. Journal of Immunology (Baltimore, Md. : 1950). 179: 7860-7. PMID 18025232 DOI: 10.4049/jimmunol.179.11.7860 |
0.346 |
|
| 2007 |
Imai M, Ohta R, Varela JC, Song H, Tomlinson S. Enhancement of antibody-dependent mechanisms of tumor cell lysis by a targeted activator of complement. Cancer Research. 67: 9535-41. PMID 17909064 DOI: 10.1158/0008-5472.Can-07-1690 |
0.357 |
|
| 2007 |
Huang Y, Qiao F, Atkinson C, Pauling E, Tomlinson S. A novel targeted inhibitor of the alternative pathway of complement Molecular Immunology. 44: 3947. DOI: 10.1016/J.Molimm.2007.06.091 |
0.323 |
|
| 2006 |
Atkinson C, Zhu H, Qiao F, Varela JC, Yu J, Song H, Kindy MS, Tomlinson S. Complement-dependent P-selectin expression and injury following ischemic stroke. Journal of Immunology (Baltimore, Md. : 1950). 177: 7266-74. PMID 17082645 DOI: 10.4049/jimmunol.177.10.7266 |
0.317 |
|
| 2006 |
Qiao F, Atkinson C, Song H, Pannu R, Singh I, Tomlinson S. Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma. The American Journal of Pathology. 169: 1039-47. PMID 16936276 DOI: 10.2353/Ajpath.2006.060248 |
0.378 |
|
| 2005 |
Imai M, Landen C, Ohta R, Cheung NK, Tomlinson S. Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer. Cancer Research. 65: 10562-8. PMID 16288049 DOI: 10.1158/0008-5472.Can-05-1894 |
0.349 |
|
| 2005 |
Atkinson C, Song H, Lu B, Qiao F, Burns TA, Holers VM, Tsokos GC, Tomlinson S. Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection. The Journal of Clinical Investigation. 115: 2444-53. PMID 16127466 DOI: 10.1172/Jci25208 |
0.427 |
|
| 2005 |
He C, Imai M, Song H, Quigg RJ, Tomlinson S. Complement inhibitors targeted to the proximal tubule prevent injury in experimental nephrotic syndrome and demonstrate a key role for C5b-9. Journal of Immunology (Baltimore, Md. : 1950). 174: 5750-7. PMID 15843577 DOI: 10.4049/Jimmunol.174.9.5750 |
0.427 |
|
| 2004 |
Imai M, Ohta R, Okada N, Tomlinson S. Inhibition of a complement regulator in vivo enhances antibody therapy in a model of mammary adenocarcinoma. International Journal of Cancer. 110: 875-81. PMID 15170670 DOI: 10.1002/Ijc.20178 |
0.324 |
|
| 2004 |
Gelderman KA, Tomlinson S, Ross GD, Gorter A. Complement function in mAb-mediated cancer immunotherapy. Trends in Immunology. 25: 158-64. PMID 15036044 DOI: 10.1016/J.It.2004.01.008 |
0.32 |
|
| 2004 |
Imai M, Hwang HY, Norris JS, Tomlinson S. The effect of dexamethasone on human mucin 1 expression and antibody-dependent complement sensitivity in a prostate cancer cell line in vitro and in vivo. Immunology. 111: 291-7. PMID 15009429 DOI: 10.1111/J.0019-2805.2004.01815.X |
0.311 |
|
| 2003 |
Song H, He C, Knaak C, Guthridge JM, Holers VM, Tomlinson S. Complement receptor 2-mediated targeting of complement inhibitors to sites of complement activation. The Journal of Clinical Investigation. 111: 1875-85. PMID 12813023 DOI: 10.1172/Jci17348 |
0.383 |
|
| 2001 |
Zhang HF, Lu S, Morrison SL, Tomlinson S. Targeting of Functional Antibody-Decay-accelerating Factor Fusion Proteins to a Cell Surface Journal of Biological Chemistry. 276: 27290-27295. PMID 11352906 DOI: 10.1074/Jbc.M100436200 |
0.345 |
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