| Year |
Citation |
Score |
| 2023 |
Chang H, Du A, Jiang J, Ren L, Liu N, Zhou X, Liang J, Gao G, Wang D. Non-canonical amino acid incorporation into AAV5 capsid enhances lung transduction in mice. Molecular Therapy. Methods & Clinical Development. 31: 101129. PMID 37886602 DOI: 10.1016/j.omtm.2023.101129 |
0.434 |
|
| 2023 |
Xu L, Wang D, Zhao L, Yang Z, Liu X, Li X, Yuan T, Wang Y, Huang T, Bian N, He Y, Chen X, Tian B, Liu Z, Luo F, et al. C9orf72 poly(PR) aggregation in nucleus induces ALS/FTD-related neurodegeneration in cynomolgus monkeys. Neurobiology of Disease. 106197. PMID 37328037 DOI: 10.1016/j.nbd.2023.106197 |
0.371 |
|
| 2023 |
Vansandt LM, Meinsohn MC, Godin P, Nagykery N, Sicher N, Kano M, Kashiwagi A, Chauvin M, Saatcioglu HD, Barnes JL, Miller AG, Thompson AK, Bateman HL, Donelan EM, González R, ... ... Wang D, et al. Durable contraception in the female domestic cat using viral-vectored delivery of a feline anti-Müllerian hormone transgene. Nature Communications. 14: 3140. PMID 37280258 DOI: 10.1038/s41467-023-38721-0 |
0.352 |
|
| 2023 |
Yang H, Brown R, Wang D, Strauss KA, Gao G. Rescue of GM3 synthase deficiency by spatially controlled rAAV-mediated ST3GAL5 delivery. Jci Insight. PMID 37014712 DOI: 10.1172/jci.insight.168688 |
0.474 |
|
| 2023 |
Arbab M, Matuszek Z, Kray KM, Du A, Newby GA, Blatnik AJ, Raguram A, Richter MF, Zhao KT, Levy JM, Shen MW, Arnold WD, Wang D, Xie J, Gao G, et al. Base editing rescue of spinal muscular atrophy in cells and in mice. Science (New York, N.Y.). eadg6518. PMID 36996170 DOI: 10.1126/science.adg6518 |
0.423 |
|
| 2022 |
Wang D, Xue X, Gunn G, Du M, Siddiqui A, Weetall M, Keeling KM. Ataluren suppresses a premature termination codon in an MPS I-H mouse. Journal of Molecular Medicine (Berlin, Germany). PMID 35857082 DOI: 10.1007/s00109-022-02232-0 |
0.711 |
|
| 2022 |
Davidson BL, Gao G, Berry-Kravis E, Bradbury A, Bönnemann C, Buxbaum JD, Corcoran GR, Gray SJ, Gray-Edwards H, Kleiman RJ, Shaywitz A, Wang D, Zoghbi HY, Flotte TR, Tauscher-Wisniewski S, et al. GENE-BASED THERAPEUTICS FOR RARE GENETIC NEURODEVELOPMENTAL PSYCHIATRIC DISORDERS. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 35585789 DOI: 10.1016/j.ymthe.2022.05.014 |
0.38 |
|
| 2022 |
Wang J, Zhang Y, Mendonca CA, Yukselen O, Muneeruddin K, Ren L, Liang J, Zhou C, Xie J, Li J, Jiang Z, Kucukural A, Shaffer SA, Gao G, Wang D. AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice. Nature. 604: 343-348. PMID 35322228 DOI: 10.1038/s41586-022-04533-3 |
0.527 |
|
| 2021 |
Ibraheim R, Tai PWL, Mir A, Javeed N, Wang J, Rodríguez TC, Namkung S, Nelson S, Khokhar ES, Mintzer E, Maitland S, Chen Z, Cao Y, Tsagkaraki E, Wolfe SA, ... Wang D, et al. Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo. Nature Communications. 12: 6267. PMID 34725353 DOI: 10.1038/s41467-021-26518-y |
0.411 |
|
| 2021 |
Liang SQ, Walkey CJ, Martinez AE, Su Q, Dickinson ME, Wang D, Lagor WR, Heaney JD, Gao G, Xue W. AAV5 delivery of CRISPR/Cas9 supports effective genome editing in mouse lung airway. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34695545 DOI: 10.1016/j.ymthe.2021.10.023 |
0.369 |
|
| 2021 |
Meinsohn MC, Saatcioglu HD, Wei L, Li Y, Horn H, Chauvin M, Kano M, Nguyen NMP, Nagykery N, Kashiwagi A, Samore WR, Wang D, Oliva E, Gao G, Morris ME, et al. Single-cell sequencing reveals suppressive transcriptional programs regulated by MIS/AMH in neonatal ovaries. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33980714 DOI: 10.1073/pnas.2100920118 |
0.349 |
|
| 2021 |
Yang H, Brown RH, Wang D, Strauss KA, Gao G. AAV-Mediated Gene Therapy for Glycosphingolipid Biosynthesis Deficiencies. Trends in Molecular Medicine. PMID 33714697 DOI: 10.1016/j.molmed.2021.02.004 |
0.428 |
|
| 2020 |
Tran NT, Heiner C, Weber K, Weiand M, Wilmot D, Xie J, Wang D, Brown A, Manokaran S, Su Q, Zapp ML, Gao G, Tai PWL. AAV-Genome Population Sequencing of Vectors Packaging CRISPR Components Reveals Design-Influenced Heterogeneity. Molecular Therapy. Methods & Clinical Development. 18: 639-651. PMID 32775498 DOI: 10.1016/J.Omtm.2020.07.007 |
0.474 |
|
| 2020 |
Yang YS, Xie J, Chaugule S, Wang D, Kim JM, Kim J, Tai PWL, Seo SK, Gravallese E, Gao G, Shim JH. Bone-Targeting AAV-Mediated Gene Silencing in Osteoclasts for Osteoporosis Therapy. Molecular Therapy. Methods & Clinical Development. 17: 922-935. PMID 32405514 DOI: 10.1016/J.Omtm.2020.04.010 |
0.418 |
|
| 2020 |
Wang D, Zhang F, Gao G. CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors. Cell. 181: 136-150. PMID 32243786 DOI: 10.1016/J.Cell.2020.03.023 |
0.473 |
|
| 2019 |
Wang D, Niu Y, Ren L, Kang Y, Tai PWL, Si C, Mendonca CA, Ma H, Gao G, Ji W. Gene Delivery to Nonhuman Primate Preimplantation Embryos Using Recombinant Adeno-Associated Virus. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1900440. PMID 31728271 DOI: 10.1002/Advs.201900440 |
0.472 |
|
| 2019 |
Yang YS, Xie J, Wang D, Kim JM, Tai PWL, Gravallese E, Gao G, Shim JH. Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis. Nature Communications. 10: 2958. PMID 31273195 DOI: 10.1038/S41467-019-10809-6 |
0.434 |
|
| 2019 |
Saatcioglu HD, Kano M, Horn H, Zhang L, Samore W, Nagykery N, Meinsohn MC, Hyun M, Suliman R, Poulo J, Hsu J, Sacha C, Wang D, Gao G, Lage K, et al. Single-cell sequencing of neonatal uterus reveals an endometrial progenitor indispensable for fertility. Elife. 8. PMID 31232694 DOI: 10.7554/Elife.46349.001 |
0.423 |
|
| 2019 |
Xiao Y, Muhuri M, Li S, Qin W, Xu G, Luo L, Li J, Letizia AJ, Wang SK, Chan YK, Wang C, Fuchs SP, Wang D, Su Q, Nahid MA, et al. Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity. Jci Insight. 5. PMID 31112525 DOI: 10.1172/Jci.Insight.99052 |
0.464 |
|
| 2019 |
Wang D, Tai PWL, Gao G. Adeno-associated virus vector as a platform for gene therapy delivery. Nature Reviews. Drug Discovery. PMID 30710128 DOI: 10.1038/S41573-019-0012-9 |
0.5 |
|
| 2019 |
Saatcioglu HD, Kano M, Horn H, Zhang L, Samore W, Nagykery N, Meinsohn M, Hyun M, Suliman R, Poulo J, Hsu J, Sacha C, Wang D, Gao G, Lage K, et al. Author response: Single-cell sequencing of neonatal uterus reveals an Misr2+ endometrial progenitor indispensable for fertility Elife. DOI: 10.7554/Elife.46349.036 |
0.401 |
|
| 2018 |
Wang D, Zhong L, Li M, Li J, Tran K, Ren L, He R, Xie J, Moser RP, Fraser C, Kuchel T, Sena-Esteves M, Flotte TR, Aronin N, Gao G. Adeno-Associated Virus Neutralizing Antibodies in Large Animals and Their Impact on Brain Intraparenchymal Gene Transfer. Molecular Therapy. Methods & Clinical Development. 11: 65-72. PMID 30397628 DOI: 10.1016/J.Omtm.2018.09.003 |
0.482 |
|
| 2018 |
Gong Y, Berenson A, Laheji F, Gao G, Wang D, Ng C, Volak A, Kok R, Kreouzis V, Dijkstra I, Kemp S, Maguire CA, Eichler F. Intrathecal Adeno-Associated Virus Vector-mediated Gene Delivery for Adrenomyeloneuropathy. Human Gene Therapy. PMID 30358470 DOI: 10.1089/Hum.2018.079 |
0.484 |
|
| 2018 |
Wang D, Li J, Song CQ, Tran K, Mou H, Wu PH, Tai PWL, Mendonca CA, Ren L, Wang BY, Su Q, Gessler DJ, Zamore PD, Xue W, Gao G. Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice. Nature Biotechnology. PMID 30102296 DOI: 10.1038/Nbt.4219 |
0.539 |
|
| 2018 |
Wang D, Li S, Gessler DJ, Xie J, Zhong L, Li J, Tran K, Van Vliet K, Ren L, Su Q, He R, Goetzmann JE, Flotte TR, Agbandje-McKenna M, Gao G. A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates. Molecular Therapy. Methods & Clinical Development. 9: 234-246. PMID 29766031 DOI: 10.1016/J.Omtm.2018.03.004 |
0.515 |
|
| 2018 |
Song CQ, Wang D, Jiang T, O'Connor K, Tang Q, Cai L, Li X, Weng Z, Yin H, Gao G, Mueller C, Flotte TR, Xue W. In vivo genome editing partially restores alpha1-antitrypsin in a murine model of AAT deficiency. Human Gene Therapy. PMID 29597895 DOI: 10.1089/Hum.2017.225 |
0.559 |
|
| 2018 |
Wang D, Li J, Tran K, Burt DR, Zhong L, Gao G. Slow Infusion of Recombinant Adeno-Associated Viruses into the Mouse Cerebrospinal Fluid Space. Human Gene Therapy Methods. PMID 29596011 DOI: 10.1089/Hgtb.2017.250 |
0.46 |
|
| 2018 |
Wang D, Gao G. Taking a Hint from Structural Biology: To Better Understand AAV Transport across the BBB. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29398483 DOI: 10.1016/J.Ymthe.2018.01.005 |
0.381 |
|
| 2018 |
Yoon Y, Wang D, Tai PWL, Riley J, Gao G, Rivera-Pérez JA. Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses. Nature Communications. 9: 412. PMID 29379011 DOI: 10.1038/S41467-017-02706-7 |
0.532 |
|
| 2017 |
Li D, Liu C, Yang C, Wang D, Wu D, Qi Y, Su Q, Gao G, Xu Z, Guo Y. Slow intrathecal injection of rAAVrh10 enhances its transduction of spinal cord and therapeutic efficacy in a mutant SOD1 model of ALS. Neuroscience. PMID 29024785 DOI: 10.1016/J.Neuroscience.2017.10.001 |
0.483 |
|
| 2017 |
Xie J, Mao Q, Tai PWL, He R, Ai J, Su Q, Zhu Y, Ma H, Li J, Gong S, Wang D, Gao Z, Li M, Zhong L, Zhou H, et al. Short DNA Hairpins Compromise Recombinant Adeno-Associated Virus Genome Homogeneity. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28462820 DOI: 10.1016/J.Ymthe.2017.03.028 |
0.485 |
|
| 2017 |
Kano M, Sosulski AE, Zhang L, Saatcioglu HD, Wang D, Nagykery N, Sabatini ME, Gao G, Donahoe PK, Pépin D. AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137855 DOI: 10.1073/Pnas.1620729114 |
0.473 |
|
| 2016 |
Murlidharan G, Sakamoto K, Rao L, Corriher T, Wang D, Gao G, Sullivan P, Asokan A. CNS-restricted Transduction and CRISPR/Cas9-mediated Gene Deletion with an Engineered AAV Vector. Molecular Therapy. Nucleic Acids. 5: e338. PMID 27434683 DOI: 10.1038/Mtna.2016.49 |
0.496 |
|
| 2016 |
Wang D, Mou H, Tran K, Li J, Wang BY, Gessler DJ, Tai PW, Su Q, Xue W, Gao G. 733. Somatically Repairing Compound Heterozygous Recessive Mutations by Chromosomal Cut-and-Paste for In Vivo Gene Therapy Molecular Therapy. 24: S289. DOI: 10.1016/S1525-0016(16)33541-9 |
0.549 |
|
| 2016 |
Wang D, Tran K, Wang BY, Xu G, Li M, Ma H, He R, Su Q, Zamore PD, Gao G. 570. Transient Reconstitution of Cas9 Protein for Safer Gene Editing In Vivo - A Ferry Tale Starring rAAV Capsid Molecular Therapy. 24: S227-S228. DOI: 10.1016/S1525-0016(16)33378-0 |
0.479 |
|
| 2015 |
Ai J, Wang D, Wei Q, Li H, Gao G. Adeno-associated Virus Serotype Vectors Efficiently Transduce Normal Prostate Tissue and Prostate Cancer Cells. European Urology. PMID 26526960 DOI: 10.1016/J.Eururo.2015.10.019 |
0.432 |
|
| 2015 |
Xiao D, Cui Y, Xu F, Xu XX, Gao GX, Wang YX, Guo ZX, Wang D, Wang NN. The Protein Phosphatase SSPP Directly Interacts with the Cytoplasmic Domain of AtSARK and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiology. PMID 26304848 DOI: 10.1104/pp.15.01112 |
0.326 |
|
| 2015 |
Pépin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK. AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26216943 DOI: 10.1073/Pnas.1510604112 |
0.459 |
|
| 2015 |
Wang D, Mou H, Li S, Li Y, Hough S, Tran K, Li J, Yin H, Anderson DG, Sontheimer EJ, Weng Z, Gao G, Xue W. Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses. Human Gene Therapy. 26: 432-42. PMID 26086867 DOI: 10.1089/Hum.2015.087 |
0.469 |
|
| 2015 |
Guo Y, Wang D, Qiao T, Yang C, Su Q, Gao G, Xu Z. A Single Injection of Recombinant Adeno-Associated Virus into the Lumbar Cistern Delivers Transgene Expression Throughout the Whole Spinal Cord. Molecular Neurobiology. PMID 26050084 DOI: 10.1007/S12035-015-9223-1 |
0.367 |
|
| 2015 |
Pepin D, Sosulski A, Hendren K, Zhang LH, Nicolaou F, Wang D, Gao G, Donahoe PK. Abstract AS25: An adeno-associated virus (AAV) 9 vector delivering modified human mullerian inhibiting substance (MIS) as a gene therapy for ovarian cancer Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-As25 |
0.462 |
|
| 2015 |
Murlidharan G, Rao L, Wang D, Corriher T, Seok-Oh K, Gao G, Jude Samulski R, Tarantal AF, Asokan A. 14. Next Generation AAV Vectors for Limiting Systemic Leakage and Improving Safety Following CNS Administration Molecular Therapy. 23: S6. DOI: 10.1016/S1525-0016(16)33618-8 |
0.489 |
|
| 2015 |
Bedwell DM, Wang D, Welch EM, Keeling KM. The nonsense suppression drug PTC124 restored alpha-l-iduronidase activity and reduces glycosaminoglycan accumulation in MPS IH mice carrying the Idua-W402X mutation Molecular Genetics and Metabolism. 114: S20. DOI: 10.1016/J.Ymgme.2014.12.026 |
0.75 |
|
| 2014 |
Wang D, Gao G. State-of-the-art human gene therapy: part II. Gene therapy strategies and clinical applications. Discovery Medicine. 18: 151-61. PMID 25227756 |
0.424 |
|
| 2014 |
Wang D, Gao G. State-of-the-art human gene therapy: part I. Gene delivery technologies. Discovery Medicine. 18: 67-77. PMID 25091489 |
0.413 |
|
| 2014 |
Liu BX, Liu YJ, Gao GP, Wang D, Zhou RH, Ma Q, Zhang Y, Yu XQ, Zheng H. [Applications of platelet antigen gene typing and matching in the platelet transfusion]. Zhongguo Shi Yan Xue Ye Xue Za Zhi / Zhongguo Bing Li Sheng Li Xue Hui = Journal of Experimental Hematology / Chinese Association of Pathophysiology. 22: 199-203. PMID 24598678 DOI: 10.7534/j.issn.1009-2137.2014.01.039 |
0.312 |
|
| 2014 |
Wang D, Zhong L, Nahid MA, Gao G. The potential of adeno-associated viral vectors for gene delivery to muscle tissue. Expert Opinion On Drug Delivery. 11: 345-64. PMID 24386892 DOI: 10.1517/17425247.2014.871258 |
0.473 |
|
| 2013 |
Keeling KM, Wang D, Dai Y, Murugesan S, Chenna B, Clark J, Belakhov V, Kandasamy J, Velu SE, Baasov T, Bedwell DM. Attenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppression. Plos One. 8: e60478. PMID 23593225 DOI: 10.1371/Journal.Pone.0060478 |
0.766 |
|
| 2012 |
Liu BX, Gao GP, Wang D, Zhang Y, Yu XQ, Xia DM, Zhou RH, Zhang H, Ma Q, Liu J. [HPA distribution characteristics of platelet donor population in Mudanjiang area of China and establishment of its database]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 20: 757-61. PMID 22739197 |
0.318 |
|
| 2012 |
Keeling KM, Wang D, Conard SE, Bedwell DM. Suppression of premature termination codons as a therapeutic approach. Critical Reviews in Biochemistry and Molecular Biology. 47: 444-63. PMID 22672057 DOI: 10.3109/10409238.2012.694846 |
0.731 |
|
| 2012 |
Wang D, Belakhov V, Kandasamy J, Baasov T, Li SC, Li YT, Bedwell DM, Keeling KM. The designer aminoglycoside NB84 significantly reduces glycosaminoglycan accumulation associated with MPS I-H in the Idua-W392X mouse. Molecular Genetics and Metabolism. 105: 116-25. PMID 22056610 DOI: 10.1016/J.Ymgme.2011.10.005 |
0.773 |
|
| 2010 |
Ren X, Xu C, Zhan C, Yang Y, Shi L, Wang F, Wang C, Xia Y, Yang B, Wu G, Wang P, Li X, Wang D, Xiong X, Liu J, et al. Identification of NPPA variants associated with atrial fibrillation in a Chinese GeneID population. Clinica Chimica Acta; International Journal of Clinical Chemistry. 411: 481-5. PMID 20064500 DOI: 10.1016/J.Cca.2009.12.019 |
0.303 |
|
| 2010 |
Wang D, Shukla C, Liu X, Schoeb TR, Clarke LA, Bedwell DM, Keeling KM. Characterization of an MPS I-H knock-in mouse that carries a nonsense mutation analogous to the human IDUA-W402X mutation. Molecular Genetics and Metabolism. 99: 62-71. PMID 19751987 DOI: 10.1016/J.Ymgme.2009.08.002 |
0.768 |
|
| 2010 |
Wang D, Shukla C, Liu X, Schoeb TR, Clarke LA, Bedwell DM, Keeling KM. Corrigendum to "Characterization of an MPS I-H knock-in mouse that carries a nonsense mutation analogous to the human IDUA-W402X mutation" [Mol. Genet. Metab. 99 (2010) 62-71] (DOI:10.1016/j.ymgme.2009.08.002) Molecular Genetics and Metabolism. 99: 439. DOI: 10.1016/J.Ymgme.2009.12.013 |
0.757 |
|
| 2009 |
Bedwell D, Wang D, Shukla C, Liu X, Yeh S, Welch E, Schoeb T, Keeling K. 12. Suppression of a nonsense mutation in a mouse model of Hurler syndrome Molecular Genetics and Metabolism. 96: S14. DOI: 10.1016/J.Ymgme.2008.11.013 |
0.744 |
|
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