| Year |
Citation |
Score |
| 2022 |
Angelozzi M, Pellegrino da Silva R, Gonzalez MV, Lefebvre V. Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors. Cell Reports. 40: 111045. PMID 35830813 DOI: 10.1016/j.celrep.2022.111045 |
0.368 |
|
| 2022 |
Li L, Medina-Menéndez C, García-Corzo L, Córdoba-Beldad CM, Quiroga AC, Calleja Barca E, Zinchuk V, Muñoz-López S, Rodríguez-Martín P, Ciorraga M, Colmena I, Fernández S, Vicario C, Nicolis SK, Lefebvre V, et al. SoxD genes are required for adult neural stem cell activation. Cell Reports. 38: 110313. PMID 35108528 DOI: 10.1016/j.celrep.2022.110313 |
0.369 |
|
| 2021 |
Mino N, Muro R, Ota A, Nitta S, Lefebvre V, Nitta T, Fujio K, Takayanagi H. The Transcription Factor Sox4 is Required for Thymic Tuft Cell Development. International Immunology. PMID 34687536 DOI: 10.1093/intimm/dxab098 |
0.347 |
|
| 2021 |
Haseeb A, Kc R, Angelozzi M, de Charleroy C, Rux D, Tower RJ, Yao L, Pellegrino da Silva R, Pacifici M, Qin L, Lefebvre V. SOX9 keeps growth plates and articular cartilage healthy by inhibiting chondrocyte dedifferentiation/osteoblastic redifferentiation. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33597301 DOI: 10.1073/pnas.2019152118 |
0.361 |
|
| 2020 |
Tsingas M, Ottone OK, Haseeb A, Barve RA, Shapiro IM, Lefebvre V, Risbud MV. Sox9 deletion causes severe intervertebral disc degeneration characterized by apoptosis, matrix remodeling, and compartment-specific transcriptomic changes. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 33027692 DOI: 10.1016/j.matbio.2020.09.003 |
0.313 |
|
| 2019 |
Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H. SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nature Communications. 10: 4042. PMID 31492871 DOI: 10.1038/S41467-019-11880-9 |
0.327 |
|
| 2019 |
Lefebvre V, Angelozzi M, Haseeb A. SOX9 in cartilage development and disease. Current Opinion in Cell Biology. 61: 39-47. PMID 31382142 DOI: 10.1016/j.ceb.2019.07.008 |
0.339 |
|
| 2019 |
Haseeb A, Lefebvre V. The SOXE transcription factors-SOX8, SOX9 and SOX10-share a bi-partite transactivation mechanism. Nucleic Acids Research. 47: 6917-6931. PMID 31194875 DOI: 10.1093/nar/gkz523 |
0.334 |
|
| 2019 |
Lefebvre V. Roles and regulation of SOX transcription factors in skeletogenesis. Current Topics in Developmental Biology. 133: 171-193. PMID 30902252 DOI: 10.1016/bs.ctdb.2019.01.007 |
0.387 |
|
| 2018 |
Liu CF, Angelozzi M, Haseeb A, Lefebvre V. SOX9 is dispensable for the initiation of epigenetic remodeling and the activation of marker genes at the onset of chondrogenesis. Development (Cambridge, England). 145. PMID 30021842 DOI: 10.1242/dev.164459 |
0.413 |
|
| 2018 |
Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EM, Feitz WF, van Eerde AM, Lefebvre V, Knoers NV, Tabatabaei M, Schulz H, McNeill H, Schaefer F, et al. Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT). Kidney International. PMID 29459093 DOI: 10.1016/J.Kint.2017.11.026 |
0.303 |
|
| 2017 |
Lefebvre V, Dvir-Ginzberg M. SOX9 and the many facets of its regulation in the chondrocyte lineage. Connective Tissue Research. 58: 2-14. PMID 27128146 DOI: 10.1080/03008207.2016.1183667 |
0.4 |
|
| 2016 |
Liu CF, Samsa WE, Zhou G, Lefebvre V. Transcriptional control of chondrocyte specification and differentiation. Seminars in Cell & Developmental Biology. PMID 27771362 DOI: 10.1016/j.semcdb.2016.10.004 |
0.415 |
|
| 2016 |
Bar Oz M, Kumar A, Elayyan J, Reich E, Binyamin M, Kandel L, Liebergall M, Steinmeyer J, Lefebvre V, Dvir-Ginzberg M. Acetylation reduces SOX9 nuclear entry and ACAN gene transactivation in human chondrocytes. Aging Cell. 15: 499-508. PMID 26910618 DOI: 10.1111/acel.12456 |
0.3 |
|
| 2016 |
Lefebvre V, Bhattaram P. SOXC Genes and the Control of Skeletogenesis. Current Osteoporosis Reports. 14: 32-8. PMID 26830765 DOI: 10.1007/S11914-016-0296-1 |
0.36 |
|
| 2015 |
Bhattaram P, Kato K, Lefebvre V. Progenitor cell fate, SOXC and WNT. Oncotarget. 6: 24596-7. PMID 26309080 DOI: 10.18632/Oncotarget.5237 |
0.442 |
|
| 2015 |
Liu CF, Lefebvre V. The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis. Nucleic Acids Research. 43: 8183-203. PMID 26150426 DOI: 10.1093/nar/gkv688 |
0.427 |
|
| 2015 |
Huang AH, Riordan TJ, Pryce B, Weibel JL, Watson SS, Long F, Lefebvre V, Harfe BD, Stadler HS, Akiyama H, Tufa SF, Keene DR, Schweitzer R. Musculoskeletal integration at the wrist underlies the modular development of limb tendons. Development (Cambridge, England). 142: 2431-41. PMID 26062940 DOI: 10.1242/Dev.122374 |
0.374 |
|
| 2015 |
Yao B, Wang Q, Liu CF, Bhattaram P, Li W, Mead TJ, Crish JF, Lefebvre V. The SOX9 upstream region prone to chromosomal aberrations causing campomelic dysplasia contains multiple cartilage enhancers. Nucleic Acids Research. 43: 5394-408. PMID 25940622 DOI: 10.1093/Nar/Gkv426 |
0.337 |
|
| 2015 |
Kato K, Bhattaram P, Penzo-Méndez A, Gadi A, Lefebvre V. SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 25761772 DOI: 10.1002/Jbmr.2504 |
0.386 |
|
| 2015 |
Lefebvre V, Bhattaram P. SoxC transcription factors in skeletogenesis and cartilage differentiation Osteoarthritis and Cartilage. 23: A23. DOI: 10.1016/J.JOCA.2015.02.055 |
0.346 |
|
| 2013 |
Ohta S, Misawa A, Lefebvre V, Okano H, Kawakami Y, Toda M. Sox6 up-regulation by macrophage migration inhibitory factor promotes survival and maintenance of mouse neural stem/progenitor cells. Plos One. 8: e74315. PMID 24066135 DOI: 10.1371/Journal.Pone.0074315 |
0.403 |
|
| 2013 |
Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L. Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells. The Journal of Biological Chemistry. 288: 18429-38. PMID 23649630 DOI: 10.1074/Jbc.M113.478503 |
0.364 |
|
| 2013 |
Mead TJ, Wang Q, Bhattaram P, Dy P, Afelik S, Jensen J, Lefebvre V. A far-upstream (-70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration. Nucleic Acids Research. 41: 4459-69. PMID 23449223 DOI: 10.1093/Nar/Gkt140 |
0.381 |
|
| 2013 |
Ramezani-Rad P, Geng H, Hurtz C, Chan LN, Chen Z, Jumaa H, Melnick A, Paietta E, Carroll WL, Willman CL, Lefebvre V, Müschen M. SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia. Blood. 121: 148-55. PMID 23152540 DOI: 10.1182/Blood-2012-05-428938 |
0.308 |
|
| 2012 |
Dy P, Wang W, Bhattaram P, Wang Q, Wang L, Ballock RT, Lefebvre V. Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes. Developmental Cell. 22: 597-609. PMID 22421045 DOI: 10.1016/J.Devcel.2011.12.024 |
0.357 |
|
| 2012 |
Zhang H, Ye M, Alberich-Jordà M, Amabile G, Staber PB, Valk PJM, Delwel R, Lefebvre V, Bonifer C, Tenen DG. Identification of Sox4 As Key Oncogene in Leukemias with Mutated or Silenced C/EBPα Blood. 120: 114-114. DOI: 10.1182/BLOOD.V120.21.114.114 |
0.305 |
|
| 2011 |
Akiyama H, Lefebvre V. Unraveling the transcriptional regulatory machinery in chondrogenesis. Journal of Bone and Mineral Metabolism. 29: 390-5. PMID 21594584 DOI: 10.1007/s00774-011-0273-9 |
0.565 |
|
| 2011 |
Nagy A, Kénesi E, Rentsendorj O, Molnár A, Szénási T, Sinkó I, Zvara A, Oommen ST, Barta E, Puskás LG, Lefebvre V, Kiss I. Evolutionarily conserved, growth plate zone-specific regulation of the matrilin-1 promoter: L-Sox5/Sox6 and Nfi factors bound near TATA finely tune activation by Sox9. Molecular and Cellular Biology. 31: 686-99. PMID 21173167 DOI: 10.1128/MCB.00019-10 |
0.314 |
|
| 2010 |
Bhattaram P, Penzo-Méndez A, Sock E, Colmenares C, Kaneko KJ, Vassilev A, Depamphilis ML, Wegner M, Lefebvre V. Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nature Communications. 1: 9. PMID 20596238 DOI: 10.1038/Ncomms1008 |
0.34 |
|
| 2010 |
Dy P, Smits P, Silvester A, Penzo-Méndez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V. Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Developmental Biology. 341: 346-59. PMID 20206616 DOI: 10.1016/J.Ydbio.2010.02.024 |
0.344 |
|
| 2010 |
Lefebvre V. The SoxD transcription factors--Sox5, Sox6, and Sox13--are key cell fate modulators. The International Journal of Biochemistry & Cell Biology. 42: 429-32. PMID 19647094 DOI: 10.1016/j.biocel.2009.07.016 |
0.41 |
|
| 2008 |
Han Y, Lefebvre V. L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer. Molecular and Cellular Biology. 28: 4999-5013. PMID 18559420 DOI: 10.1128/MCB.00695-08 |
0.441 |
|
| 2008 |
Dy P, Penzo-Méndez A, Wang H, Pedraza CE, Macklin WB, Lefebvre V. The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. Nucleic Acids Research. 36: 3101-17. PMID 18403418 DOI: 10.1093/Nar/Gkn162 |
0.364 |
|
| 2007 |
Lefebvre V, Dumitriu B, Penzo-Méndez A, Han Y, Pallavi B. Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors. The International Journal of Biochemistry & Cell Biology. 39: 2195-214. PMID 17625949 DOI: 10.1016/j.biocel.2007.05.019 |
0.362 |
|
| 2006 |
Dumitriu B, Patrick MR, Petschek JP, Cherukuri S, Klingmuller U, Fox PL, Lefebvre V. Sox6 cell-autonomously stimulates erythroid cell survival, proliferation, and terminal maturation and is thereby an important enhancer of definitive erythropoiesis during mouse development. Blood. 108: 1198-207. PMID 16627753 DOI: 10.1182/blood-2006-02-004184 |
0.328 |
|
| 2005 |
Lefebvre V, Smits P. Transcriptional control of chondrocyte fate and differentiation. Birth Defects Research. Part C, Embryo Today : Reviews. 75: 200-12. PMID 16187326 DOI: 10.1002/bdrc.20048 |
0.317 |
|
| 2004 |
Gebhard S, Pöschl E, Riemer S, Bauer E, Hattori T, Eberspaecher H, Zhang Z, Lefebvre V, de Crombrugghe B, von der Mark K. A highly conserved enhancer in mammalian type X collagen genes drives high levels of tissue-specific expression in hypertrophic cartilage in vitro and in vivo. Matrix Biology : Journal of the International Society For Matrix Biology. 23: 309-22. PMID 15464363 DOI: 10.1016/j.matbio.2004.05.010 |
0.679 |
|
| 2004 |
Smits P, Dy P, Mitra S, Lefebvre V. Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate. The Journal of Cell Biology. 164: 747-58. PMID 14993235 DOI: 10.1083/jcb.200312045 |
0.328 |
|
| 2003 |
Smits P, Lefebvre V. Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs. Development (Cambridge, England). 130: 1135-48. PMID 12571105 DOI: 10.1242/dev.00331 |
0.367 |
|
| 2001 |
Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B, Lefebvre V. The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Developmental Cell. 1: 277-90. PMID 11702786 DOI: 10.1016/S1534-5807(01)00003-X |
0.631 |
|
| 2001 |
de Crombrugghe B, Lefebvre V, Nakashima K. Regulatory mechanisms in the pathways of cartilage and bone formation. Current Opinion in Cell Biology. 13: 721-7. PMID 11698188 DOI: 10.1016/s0955-0674(00)00276-3 |
0.561 |
|
| 2001 |
Lefebvre V, Behringer RR, de Crombrugghe B. L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway. Osteoarthritis and Cartilage. 9: S69-75. PMID 11680692 DOI: 10.1053/Joca.2001.0447 |
0.616 |
|
| 2001 |
Uusitalo H, Hiltunen A, Ahonen M, Gao T, Lefebvre V, Harley V, Kähäri V, Vuorio E. Accelerated up-regulation of L-Sox5, Sox6, and Sox9 by BMP-2 gene transfer during murine fracture healing. Journal of Bone and Mineral Research. 16: 1837-1845. PMID 11585348 DOI: 10.1359/Jbmr.2001.16.10.1837 |
0.453 |
|
| 2001 |
Panda DK, Miao D, Lefebvre V, Hendy GN, Goltzman D. The Transcription Factor SOX9 Regulates Cell Cycle and Differentiation Genes in Chondrocytic CFK2 Cells Journal of Biological Chemistry. 276: 41229-41236. PMID 11514554 DOI: 10.1074/jbc.M104231200 |
0.452 |
|
| 2001 |
Deere M, Hall CR, Gunning KB, LeFebvre V, Ridall AL, Hecht JT. Analysis of the promoter region of human cartilage oligomeric matrix protein (COMP). Matrix Biology. 19: 783-792. PMID 11223338 DOI: 10.1016/S0945-053X(00)00127-X |
0.521 |
|
| 2000 |
de Crombrugghe B, Lefebvre V, Behringer RR, Bi W, Murakami S, Huang W. Transcriptional mechanisms of chondrocyte differentiation. Matrix Biology : Journal of the International Society For Matrix Biology. 19: 389-94. PMID 10980415 DOI: 10.1016/S0945-053X(00)00094-9 |
0.724 |
|
| 2000 |
Huang W, Zhou X, Lefebvre V, de Crombrugghe B. Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer. Molecular and Cellular Biology. 20: 4149-58. PMID 10805756 DOI: 10.1128/Mcb.20.11.4149-4158.2000 |
0.666 |
|
| 2000 |
Murakami S, Lefebvre V, de Crombrugghe B. Potent inhibition of the master chondrogenic factor Sox9 gene by interleukin-1 and tumor necrosis factor-alpha. The Journal of Biological Chemistry. 275: 3687-92. PMID 10652367 DOI: 10.1074/Jbc.275.5.3687 |
0.715 |
|
| 2000 |
Huang W, Zhou X, Lefebvre V, Crombrugghe BD. Erratum: Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase a enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer (Molecular and Cellular Biology (2000) 20:11 (p. 4149-4158)) Molecular and Cellular Biology. 20. DOI: 10.1128/Mcb.20.20.7838-7838.2000 |
0.338 |
|
| 1999 |
Xie WF, Zhang X, Sakano S, Lefebvre V, Sandell LJ. Trans-activation of the Mouse Cartilage-Derived Retinoic Acid-Sensitive Protein Gene by Sox9 Journal of Bone and Mineral Research. 14: 757-763. PMID 10320524 DOI: 10.1359/Jbmr.1999.14.5.757 |
0.503 |
|
| 1998 |
Lefebvre V, Li P, de Crombrugghe B. A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. The Embo Journal. 17: 5718-33. PMID 9755172 DOI: 10.1093/Emboj/17.19.5718 |
0.674 |
|
| 1998 |
Bridgewater LC, Lefebvre V, De Crombrugghe B. Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer Journal of Biological Chemistry. 273: 14998-15006. PMID 9614107 DOI: 10.1074/jbc.273.24.14998 |
0.671 |
|
| 1998 |
Zhou G, Lefebvre V, Zhang Z, Eberspaecher H, de Crombrugghe B. Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo. The Journal of Biological Chemistry. 273: 14989-97. PMID 9614106 DOI: 10.1074/jbc.273.24.14989 |
0.656 |
|
| 1997 |
Zhao Q, Eberspaecher H, Lefebvre V, De Crombrugghe B. Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 209: 377-86. PMID 9264261 DOI: 10.1002/(Sici)1097-0177(199708)209:4<377::Aid-Aja5>3.0.Co;2-F |
0.621 |
|
| 1997 |
Lefebvre V, Huang W, Harley VR, Goodfellow PN, de Crombrugghe B. SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Molecular and Cellular Biology. 17: 2336-46. PMID 9121483 DOI: 10.1128/Mcb.17.4.2336 |
0.746 |
|
| 1996 |
Lefebvre V, Zhou G, Mukhopadhyay K, Smith CN, Zhang Z, Eberspaecher H, Zhou X, Sinha S, Maity SN, de Crombrugghe B. An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes. Molecular and Cellular Biology. 16: 4512-23. PMID 8754852 |
0.657 |
|
| 1996 |
Lefebvre V, Mukhopadhyay K, Zhou G, Garofalo S, Smith C, Eberspaecher H, Kimura JH, de Crombrugghe B. A 47-bp sequence of the first intron of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte Expression. Annals of the New York Academy of Sciences. 785: 284-7. PMID 8702156 DOI: 10.1111/J.1749-6632.1996.Tb56285.X |
0.625 |
|
| 1996 |
Lefebvre V, Zhou G, Mukhopadhyay K, Smith CN, Zhang Z, Eberspaecher H, Zhou X, Sinha S, Maity SN, de Crombrugghe B. An 18-bp sequence in the mouse Proα1(II) collagen gene is sufficient for cartilage expression and binds nuclear proteins that are selectively expressed in chondrocytes Matrix Biology. 15: 192. DOI: 10.1016/S0945-053X(96)90091-8 |
0.42 |
|
| 1995 |
Lefebvre V, Garofalo S, de Crombrugghe B. Type X collagen gene expression in mouse chondrocytes immortalized by a temperature-sensitive simian virus 40 large tumor antigen. The Journal of Cell Biology. 128: 239-45. PMID 7822418 DOI: 10.1083/Jcb.128.1.239 |
0.629 |
|
| 1995 |
Mukhopadhyay K, Lefebvre V, Zhou G, Garofalo S, Kimura JH, de Crombrugghe B. Use of a new rat chondrosarcoma cell line to delineate a 119-base pair chondrocyte-specific enhancer element and to define active promoter segments in the mouse pro-alpha 1(II) collagen gene. The Journal of Biological Chemistry. 270: 27711-9. PMID 7499238 DOI: 10.1074/Jbc.270.46.27711 |
0.673 |
|
| 1994 |
Lefebvre V, Garofalo S, Zhou G, Metsäranta M, Vuorio E, De Crombrugghe B. Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice. Matrix Biology : Journal of the International Society For Matrix Biology. 14: 329-35. PMID 7827756 DOI: 10.1016/0945-053X(94)90199-6 |
0.619 |
|
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