Year |
Citation |
Score |
2023 |
Williams SA, Lay FT, Bindra GK, Banjara S, Poon IKH, Phan TK, Kvansakul M, Hulett MD. Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption. Nature Communications. 14: 1170. PMID 36859344 DOI: 10.1038/s41467-023-36280-y |
0.646 |
|
2022 |
Hein MJA, Kvansakul M, Lay FT, Phan TK, Hulett MD. Defensin-lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics. Biochemical Society Transactions. PMID 35015081 DOI: 10.1042/BST20200884 |
0.635 |
|
2019 |
Lay FT, Ryan GF, Caria S, Phan TK, Veneer PK, White JA, Kvansakul M, Hulett MD. Structural and functional characterization of the membrane-permeabilizing activity of Nicotiana occidentalis defensin NoD173 and protein engineering to enhance oncolysis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802540R. PMID 30794440 DOI: 10.1096/Fj.201802540R |
0.654 |
|
2018 |
Järvå M, Phan TK, Lay FT, Caria S, Kvansakul M, Hulett MD. Human β-defensin 2 kills through phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization. Science Advances. 4: eaat0979. PMID 30050988 DOI: 10.1126/Sciadv.Aat0979 |
0.767 |
|
2018 |
Järvå M, Lay FT, Phan TK, Humble C, Poon IKH, Bleackley MR, Anderson MA, Hulett MD, Kvansakul M. X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex. Nature Communications. 9: 1962. PMID 29773800 DOI: 10.1038/S41467-018-04434-Y |
0.777 |
|
2017 |
Anasir MI, Baxter AA, Poon IKH, Hulett MD, Kvansakul M. Structural and Functional Insight into Canarypox Virus CNP058 Mediated Regulation of Apoptosis. Viruses. 9. PMID 29053589 DOI: 10.3390/V9100305 |
0.591 |
|
2017 |
Baxter AA, Lay FT, Poon IKH, Kvansakul M, Hulett MD. Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects. Cellular and Molecular Life Sciences : Cmls. PMID 28770291 DOI: 10.1007/S00018-017-2604-Z |
0.627 |
|
2017 |
Järvå M, Lay FT, Hulett MD, Kvansakul M. Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type. Febs Letters. PMID 28741756 DOI: 10.1002/1873-3468.12761 |
0.767 |
|
2017 |
Baxter AA, Poon IK, Hulett MD. The lure of the lipids: how defensins exploit membrane phospholipids to induce cytolysis in target cells. Cell Death & Disease. 8: e2712. PMID 28358378 DOI: 10.1038/cddis.2017.69 |
0.31 |
|
2017 |
Priebatsch KM, Kvansakul M, Poon IK, Hulett MD. Functional Regulation of the Plasma Protein Histidine-Rich Glycoprotein by Zn(2+) in Settings of Tissue Injury. Biomolecules. 7. PMID 28257077 DOI: 10.3390/biom7010022 |
0.598 |
|
2016 |
Priebatsch KM, Poon IK, Patel KK, Kvansakul M, Hulett MD. Divalent metal binding by histidine-rich glycoprotein (HRG) differentially regulates higher order oligomerisation and proteolytic processing. Febs Letters. PMID 27930811 DOI: 10.1002/1873-3468.12520 |
0.586 |
|
2016 |
Kvansakul M, Lay FT, Adda CG, Veneer PK, Baxter AA, Phan TK, Poon IK, Hulett MD. Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization. Proceedings of the National Academy of Sciences of the United States of America. PMID 27647905 DOI: 10.1073/Pnas.1607855113 |
0.694 |
|
2016 |
Payne JA, Bleackley MR, Lee TH, Shafee TM, Poon IK, Hulett MD, Aguilar MI, van der Weerden NL, Anderson MA. The plant defensin NaD1 introduces membrane disorder through a specific interaction with the lipid, phosphatidylinositol 4,5 bisphosphate. Biochimica Et Biophysica Acta. PMID 26896695 DOI: 10.1016/j.bbamem.2016.02.016 |
0.362 |
|
2015 |
Phan TK, Lay FT, Poon IK, Hinds MG, Kvansakul M, Hulett MD. Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation. Oncotarget. PMID 26657293 DOI: 10.18632/Oncotarget.6520 |
0.667 |
|
2015 |
Baxter AA, Richter V, Lay FT, Poon IK, Adda CG, Veneer PK, Phan TK, Bleackley MR, Anderson MA, Kvansakul M, Hulett MD. The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis. Molecular and Cellular Biology. 35: 1964-78. PMID 25802281 DOI: 10.1128/Mcb.00282-15 |
0.722 |
|
2015 |
Kuek LE, Hulett M, Davies D, Mackay G. Expression and function of a novel membrane-spanning protein, MS4A8B, in the human airways European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa919 |
0.322 |
|
2014 |
Poon IKh, Baxter AA, Lay FT, Mills GD, Adda CG, Payne JA, Phan TK, Ryan GF, White JA, Veneer PK, van der Weerden NL, Anderson MA, Kvansakul M, Hulett MD. Phosphoinositide-mediated oligomerization of a defensin induces cell lysis. Elife. 3: e01808. PMID 24692446 DOI: 10.7554/Elife.01808 |
0.692 |
|
2014 |
Poon IKH, Baxter AA, Lay FT, Mills GD, Adda CG, Payne JAE, Phan TK, Ryan GF, White JA, Veneer PK, van der Weerden NL, Anderson MA, Kvansakul M, Hulett MD. Author response Elife. 2014. DOI: 10.7554/Elife.01808.034 |
0.489 |
|
2014 |
Kvansakul M, Poon I, Baxter A, Lay F, Mills G, Adda C, Payne J, Phan T, Ryan G, Veneer P, Weerden Nvd, Anderson M, Hulett M. NaD1 forms oligomeric complexes with phosphatidylinositol to lyse cell membranes Acta Crystallographica Section A. 70. DOI: 10.1107/S2053273314089505 |
0.7 |
|
2012 |
Lay FT, Mills GD, Poon IK, Cowieson NP, Kirby N, Baxter AA, van der Weerden NL, Dogovski C, Perugini MA, Anderson MA, Kvansakul M, Hulett MD. Dimerization of plant defensin NaD1 enhances its antifungal activity. The Journal of Biological Chemistry. 287: 19961-72. PMID 22511788 DOI: 10.1074/Jbc.M111.331009 |
0.635 |
|
2012 |
Lay FT, Veneer PK, Hulett MD, Kvansakul M. Recombinant expression and purification of the tomato defensin TPP3 and its preliminary X-ray crystallographic analysis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 314-6. PMID 22442231 DOI: 10.1107/S1744309112001510 |
0.57 |
|
2012 |
Lay FT, Mills GD, Hulett MD, Kvansakul M. Crystallization and preliminary X-ray crystallographic analysis of the plant defensin NaD1 Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 68: 85-88. PMID 22232180 DOI: 10.1107/S1744309111049530 |
0.553 |
|
2009 |
Poon IK, Olsson AK, Hulett MD, Parish CR. Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage. The Biochemical Journal. 424: 27-37. PMID 19712047 DOI: 10.1042/BJ20090794 |
0.314 |
|
2006 |
Abbey JL, Hulett M, O'Neill HC. Cell surface expression of a peptide encoded by the unrearranged TCR-Vbeta8.2 gene. Molecular Immunology. 43: 1408-17. PMID 16197998 DOI: 10.1016/J.Molimm.2005.07.040 |
0.314 |
|
2005 |
Jones AL, Hulett MD, Parish CR. Histidine-rich glycoprotein: A novel adaptor protein in plasma that modulates the immune, vascular and coagulation systems. Immunology and Cell Biology. 83: 106-18. PMID 15748207 DOI: 10.1111/j.1440-1711.2005.01320.x |
0.307 |
|
2004 |
Jones AL, Hulett MD, Parish CR. Histidine-rich glycoprotein binds to cell-surface heparan sulfate via its N-terminal domain following Zn2+ chelation. The Journal of Biological Chemistry. 279: 30114-22. PMID 15138272 DOI: 10.1074/jbc.M401996200 |
0.329 |
|
2002 |
Mackay GA, Hulett MD, Cook JP, Trist HM, Henry AJ, McDonnell JM, Beavil AJ, Beavil RL, Sutton BJ, Hogarth PM, Gould HJ. Mutagenesis within human FcepsilonRIalpha differentially affects human and murine IgE binding. Journal of Immunology (Baltimore, Md. : 1950). 168: 1787-95. PMID 11823511 DOI: 10.4049/Jimmunol.168.4.1787 |
0.541 |
|
2001 |
Hulett MD, Pagler E, Hornby JR, Hogarth PM, Eyre HJ, Baker E, Crawford J, Sutherland GR, Ohms SJ, Parish CR. Isolation, tissue distribution, and chromosomal localization of a novel testis-specific human four-transmembrane gene related to CD20 and FcepsilonRI-beta. Biochemical and Biophysical Research Communications. 280: 374-9. PMID 11162526 DOI: 10.1006/Bbrc.2000.4088 |
0.456 |
|
2000 |
Rigby LJ, Trist H, Snider J, Hulett MD, Hogarth PM, Rigby LJ, Epa VC. Monoclonal antibodies and synthetic peptides define the active site of FcepsilonRI and a potential receptor antagonist. Allergy. 55: 609-19. PMID 10921459 DOI: 10.1034/j.1398-9995.2000.00485.x |
0.553 |
|
2000 |
Rigby LJ, Chandana Epa V, Mackay GA, Hulett MD, Sutton BJ, Gould HJ, Hogarth PM. Domain one of the high affinity IgE receptor, FcεRI, regulates binding to IgE through its interface with domain two Journal of Biological Chemistry. 275: 9664-9672. PMID 10734118 DOI: 10.1074/jbc.275.13.9664 |
0.557 |
|
1999 |
Maxwell KF, Powell MS, Hulett MD, Barton PA, McKenzie IF, Garrett TP, Hogarth PM. Crystal structure of the human leukocyte Fc receptor, Fc gammaRIIa. Nature Structural Biology. 6: 437-42. PMID 10331870 DOI: 10.1038/8241 |
0.577 |
|
1999 |
Hulett MD, Brinkworth RI, McKenzie IF, Hogarth PM. Fine structure analysis of interaction of FcepsilonRI with IgE. The Journal of Biological Chemistry. 274: 13345-52. PMID 10224096 DOI: 10.1074/jbc.274.19.13345 |
0.561 |
|
1998 |
Hulett MD, Hogarth PM. The second and third extracellular domains of FcgammaRI (CD64) confer the unique high affinity binding of IgG2a. Molecular Immunology. 35: 989-96. PMID 9881694 DOI: 10.1016/S0161-5890(98)00069-8 |
0.541 |
|
1996 |
Kershaw MH, Darcy PK, Hulett MD, Hogarth PM, Trapani JA, Smyth MJ. Redirected cytotoxic effector function. Requirements for expression of chimeric single chain high affinity immunoglobulin e receptors. The Journal of Biological Chemistry. 271: 21214-20. PMID 8702893 DOI: 10.1074/Jbc.271.35.21214 |
0.587 |
|
1995 |
Hulett MD, Witort E, Brinkworth RI, McKenzie IF, Hogarth PM. Multiple regions of human Fc gamma RII (CD32) contribute to the binding of IgG. The Journal of Biological Chemistry. 270: 21188-94. PMID 7673151 DOI: 10.1074/Jbc.270.36.21188 |
0.547 |
|
1994 |
Hulett MD, Hogarth PM. Molecular basis of Fc receptor function. Advances in Immunology. 57: 1-127. PMID 7872156 DOI: 10.1016/S0065-2776(08)60671-9 |
0.486 |
|
1994 |
Hogarth PM, Ierino FL, Hulett MD. Characterization of FcR Ig-binding sites and epitope mapping. Immunomethods. 4: 17-24. PMID 7520815 DOI: 10.1006/Immu.1994.1003 |
0.553 |
|
1993 |
Hulett MD, McKenzie IF, Hogarth PM. Chimeric Fc receptors identify immunoglobulin-binding regions in human Fc gamma RII and Fc epsilon RI. European Journal of Immunology. 23: 640-5. PMID 8449212 DOI: 10.1002/Eji.1830230310 |
0.547 |
|
1992 |
Hogarth PM, Hulett MD, Ierino FL, Tate B, Powell MS, Brinkworth RI. Identification of the immunoglobulin binding regions (IBR) of Fc gamma RII and Fc epsilon RI. Immunological Reviews. 125: 21-35. PMID 1372589 DOI: 10.1111/J.1600-065X.1992.Tb00623.X |
0.513 |
|
1992 |
Hogarth PM, Hulett MD, Osman N. Fc gamma receptors: gene structure and receptor function. Immunologic Research. 11: 217-25. PMID 1287117 DOI: 10.1007/Bf02919128 |
0.497 |
|
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