| Year |
Citation |
Score |
| 2020 |
Shamsi F, Xue R, Huang TL, Lundh M, Liu Y, Leiria LO, Lynes MD, Kempf E, Wang CH, Sugimoto S, Nigro P, Landgraf K, Schulz T, Li Y, Emanuelli B, ... ... Williams LT, et al. FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis. Nature Communications. 11: 1421. PMID 32184391 DOI: 10.1038/S41467-020-15055-9 |
0.36 |
|
| 2014 |
Zhang H, Pao LI, Zhou A, Brace AD, Halenbeck R, Hsu AW, Bray TL, Hestir K, Bosch E, Lee E, Wang G, Liu H, Wong BR, Kavanaugh WM, Williams LT. Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome. Proceedings of the National Academy of Sciences of the United States of America. 111: 15741-5. PMID 25331893 DOI: 10.1073/Pnas.1412009111 |
0.443 |
|
| 2014 |
Sallee NA, Lee E, Rankin A, Halenbeck R, Brace A, Williams LT, Wong B, Kavanaugh WM. Discovery of novel immune checkpoint regulators in a comprehensive library of human extracellular proteins Journal For Immunotherapy of Cancer. 2. DOI: 10.1186/2051-1426-2-S3-P142 |
0.325 |
|
| 2013 |
Harding TC, Long L, Palencia S, Zhang H, Sadra A, Hestir K, Patil N, Levin A, Hsu AW, Charych D, Brennan T, Zanghi J, Halenbeck R, Marshall SA, Qin M, ... ... Williams LT, et al. Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer. Science Translational Medicine. 5: 178ra39. PMID 23536011 DOI: 10.1126/Scitranslmed.3005414 |
0.392 |
|
| 2008 |
Lin H, Lee E, Hestir K, Leo C, Huang M, Bosch E, Halenbeck R, Wu G, Zhou A, Behrens D, Hollenbaugh D, Linnemann T, Qin M, Wong J, Chu K, ... ... Williams LT, et al. Discovery of a cytokine and its receptor by functional screening of the extracellular proteome. Science (New York, N.Y.). 320: 807-11. PMID 18467591 DOI: 10.1126/Science.1154370 |
0.406 |
|
| 2007 |
Lin H, Huang M, Leo C, Ji M, Behrens D, Bosch E, Chu K, Giese S, Halenbeck R, Hollenbaugh D, Hestir K, Lee E, Linnemann T, Qin M, Wu G, ... ... Williams LT, et al. 87 Regulation of Myeloid Growth and Differentiation by a Novel Cytokine, Interleukin-34 (IL-34), via the CSF-1 Receptor Cytokine. 39: 24. DOI: 10.1016/J.Cyto.2007.07.092 |
0.319 |
|
| 2006 |
Lin H, Huang MM, Leo C, Ji M, Wu G, Zhou A, Halenbeck R, Qin M, Linnemann T, Behrens D, Giese S, Bosch E, Justin K, Pham A, Lee E, ... ... Williams LT, et al. A Novel Cytokine, FPT025, Regulates Myeloid Growth and Differentiation Via the M-CSF Receptor. Blood. 108: 634-634. DOI: 10.1182/Blood.V108.11.634.634 |
0.383 |
|
| 2004 |
Zhang H, Dessimoz J, Beyer TA, Krampert M, Williams LT, Werner S, Grose R. Fibroblast growth factor receptor 1-IIIb is dispensable for skin morphogenesis and wound healing. European Journal of Cell Biology. 83: 3-11. PMID 15085950 DOI: 10.1078/0171-9335-00355 |
0.324 |
|
| 2001 |
Yan D, Wiesmann M, Rohan M, Chan V, Jefferson AB, Guo L, Sakamoto D, Caothien RH, Fuller JH, Reinhard C, Garcia PD, Randazzo FM, Escobedo J, Fantl WJ, Williams LT. Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 14973-8. PMID 11752446 DOI: 10.1073/Pnas.261574498 |
0.32 |
|
| 2001 |
Sun TQ, Lu B, Feng JJ, Reinhard C, Jan YN, Fantl WJ, Williams LT. PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling. Nature Cell Biology. 3: 628-36. PMID 11433294 DOI: 10.1038/35083016 |
0.384 |
|
| 2001 |
Yan D, Wallingford JB, Sun TQ, Nelson AM, Sakanaka C, Reinhard C, Harland RM, Fantl WJ, Williams LT. Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd. Proceedings of the National Academy of Sciences of the United States of America. 98: 3802-7. PMID 11274398 DOI: 10.1073/Pnas.071041898 |
0.392 |
|
| 2001 |
Cox DN, Lu B, Sun TQ, Williams LT, Jan YN. Drosophila par-1 is required for oocyte differentiation and microtubule organization. Current Biology : Cb. 11: 75-87. PMID 11231123 DOI: 10.1016/S0960-9822(01)00027-6 |
0.314 |
|
| 2000 |
Haertel-Wiesmann M, Liang Y, Fantl WJ, Williams LT. Regulation of cyclooxygenase-2 and periostin by Wnt-3 in mouse mammary epithelial cells. The Journal of Biological Chemistry. 275: 32046-51. PMID 10884377 DOI: 10.1074/Jbc.M000074200 |
0.345 |
|
| 1999 |
Tribouley C, Wallroth M, Chan V, Paliard X, Fang E, Lamson G, Pot D, Escobedo J, Williams LT. Characterization of a new member of the TNF family expressed on antigen presenting cells. Biological Chemistry. 380: 1443-7. PMID 10661873 DOI: 10.1515/Bc.1999.186 |
0.34 |
|
| 1999 |
Sakanaka C, Leong P, Xu L, Harrison SD, Williams LT. Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function. Proceedings of the National Academy of Sciences of the United States of America. 96: 12548-52. PMID 10535959 DOI: 10.1073/Pnas.96.22.12548 |
0.375 |
|
| 1999 |
Sakanaka C, Williams LT. Functional domains of axin. Importance of the C terminus as an oligomerization domain. The Journal of Biological Chemistry. 274: 14090-3. PMID 10318824 DOI: 10.1074/Jbc.274.20.14090 |
0.358 |
|
| 1998 |
Klippel A, Escobedo MA, Wachowicz MS, Apell G, Brown TW, Giedlin MA, Kavanaugh WM, Williams LT. Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation. Molecular and Cellular Biology. 18: 5699-711. PMID 9742087 DOI: 10.1128/Mcb.18.10.5699 |
0.427 |
|
| 1998 |
Jefferson AB, Klippel A, Williams LT. Inhibition of mSOS-activity by binding of phosphatidylinositol 4,5-P2 to the mSOS pleckstrin homology domain. Oncogene. 16: 2303-10. PMID 9620547 DOI: 10.1038/Sj.Onc.1201891 |
0.338 |
|
| 1998 |
Halenbeck R, MacDonald H, Roulston A, Chen TT, Conroy L, Williams LT. CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45. Current Biology : Cb. 8: 537-40. PMID 9560346 DOI: 10.1016/S0960-9822(98)79298-X |
0.354 |
|
| 1998 |
Roulston A, Reinhard C, Amiri P, Williams LT. Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha. The Journal of Biological Chemistry. 273: 10232-9. PMID 9553074 DOI: 10.1074/Jbc.273.17.10232 |
0.406 |
|
| 1998 |
Sakanaka C, Weiss JB, Williams LT. Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription. Proceedings of the National Academy of Sciences of the United States of America. 95: 3020-3. PMID 9501208 DOI: 10.1073/Pnas.95.6.3020 |
0.337 |
|
| 1998 |
Gunn MD, Ngo VN, Ansel KM, Ekland EH, Cyster JG, Williams LT. A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Nature. 391: 799-803. PMID 9486651 DOI: 10.1038/35876 |
0.311 |
|
| 1998 |
Yu W, Fantl WJ, Harrowe G, Williams LT. Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK. Current Biology : Cb. 8: 56-64. PMID 9427629 DOI: 10.1016/S0960-9822(98)70020-X |
0.357 |
|
| 1998 |
Gunn MD, Tangemann K, Tam C, Cyster JG, Rosen SD, Williams LT. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 95: 258-263. PMID 9419363 DOI: 10.1073/Pnas.95.1.258 |
0.303 |
|
| 1997 |
Lee N, MacDonald H, Reinhard C, Halenbeck R, Roulston A, Shi T, Williams LT. Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 94: 13642-7. PMID 9391079 DOI: 10.1073/Pnas.94.25.13642 |
0.369 |
|
| 1997 |
Reinhard C, Shamoon B, Shyamala V, Williams LT. Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2. The Embo Journal. 16: 1080-92. PMID 9118946 DOI: 10.1093/Emboj/16.5.1080 |
0.371 |
|
| 1997 |
Deuter-Reinhard M, Apell G, Pot D, Klippel A, Williams LT, Kavanaugh WM. SIP/SHIP inhibits Xenopus oocyte maturation induced by insulin and phosphatidylinositol 3-kinase. Molecular and Cellular Biology. 17: 2559-65. PMID 9111325 DOI: 10.1128/Mcb.17.5.2559 |
0.434 |
|
| 1997 |
Jefferson AB, Auethavekiat V, Pot DA, Williams LT, Majerus PW. Signaling inositol polyphosphate-5-phosphatase. Characterization of activity and effect of GRB2 association. The Journal of Biological Chemistry. 272: 5983-8. PMID 9038219 DOI: 10.1074/Jbc.272.9.5983 |
0.338 |
|
| 1997 |
Shinbrot E, Liao X, Williams LT. Isolation and characterization of the platelet-derived growth factor beta receptor promoter. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 208: 211-9. PMID 9022058 DOI: 10.1002/(Sici)1097-0177(199702)208:2<211::Aid-Aja8>3.0.Co;2-L |
0.314 |
|
| 1997 |
Klippel A, Kavanaugh WM, Pot D, Williams LT. A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain. Molecular and Cellular Biology. 17: 338-44. PMID 8972214 DOI: 10.1128/Mcb.17.1.338 |
0.457 |
|
| 1996 |
Martin SS, Rose DW, Saltiel AR, Klippel A, Williams LT, Olefsky JM. Phosphatidylinositol 3-kinase is necessary and sufficient for insulin- stimulated stress fiber breakdown Endocrinology. 137: 5045-5054. PMID 8895379 DOI: 10.1210/Endo.137.11.8895379 |
0.382 |
|
| 1996 |
Tanti JF, Grémeaux T, Grillo S, Calleja V, Klippel A, Williams LT, Van Obberghen E, Le Marchand-Brustel Y. Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes. The Journal of Biological Chemistry. 271: 25227-32. PMID 8810283 DOI: 10.1074/Jbc.271.41.25227 |
0.404 |
|
| 1996 |
Klippel A, Reinhard C, Kavanaugh WM, Apell G, Escobedo MA, Williams LT. Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways. Molecular and Cellular Biology. 16: 4117-27. PMID 8754810 DOI: 10.1128/Mcb.16.8.4117 |
0.458 |
|
| 1996 |
Kavanaugh WM, Pot DA, Chin SM, Deuter-Reinhard M, Jefferson AB, Norris FA, Masiarz FR, Cousens LS, Majerus PW, Williams LT. Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2. Current Biology : Cb. 6: 438-45. PMID 8723348 DOI: 10.1016/S0960-9822(02)00511-0 |
0.444 |
|
| 1996 |
Martin SS, Haruta T, Morris AJ, Klippel A, Williams LT, Olefsky JM. Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 271: 17605-8. PMID 8663595 DOI: 10.1074/Jbc.271.30.17605 |
0.407 |
|
| 1996 |
Molz L, Chen YW, Hirano M, Williams LT. Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain. The Journal of Biological Chemistry. 271: 13892-9. PMID 8662856 DOI: 10.1074/Jbc.271.23.13892 |
0.399 |
|
| 1996 |
Pronk GJ, Ramer K, Amiri P, Williams LT. Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER. Science (New York, N.Y.). 271: 808-10. PMID 8628997 DOI: 10.1126/Science.271.5250.808 |
0.37 |
|
| 1996 |
Koyama S, Chen YW, Ikeda M, Muslin AJ, Williams LT, Kikuchi A. Ras-interacting domain of RGL blocks Ras-dependent signal transduction in Xenopus oocytes. Febs Letters. 380: 113-7. PMID 8603717 DOI: 10.1016/0014-5793(96)00018-X |
0.723 |
|
| 1996 |
Kikuchi A, Williams LT. Regulation of interaction of ras p21 with RalGDS and Raf-1 by cyclic AMP-dependent protein kinase. The Journal of Biological Chemistry. 271: 588-94. PMID 8550624 DOI: 10.1074/Jbc.271.1.588 |
0.415 |
|
| 1995 |
Chu K, Niu X, Williams LT. A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 92: 11894-8. PMID 8524870 DOI: 10.1073/Pnas.92.25.11894 |
0.372 |
|
| 1995 |
MacNicol AM, Muslin AJ, Howard EL, Kikuchi A, MacNicol MC, Williams LT. Regulation of Raf-1-dependent signaling during early Xenopus development. Molecular and Cellular Biology. 15: 6686-93. PMID 8524233 DOI: 10.1128/Mcb.15.12.6686 |
0.758 |
|
| 1995 |
Kamohara S, Hayashi H, Todaka M, Kanai F, Ishii K, Imanaka T, Escobedo JA, Williams LT, Ebina Y. Platelet-derived growth factor triggers translocation of the insulin-regulatable glucose transporter (type 4) predominantly through phosphatidylinositol 3-kinase binding sites on the receptor. Proceedings of the National Academy of Sciences of the United States of America. 92: 1077-81. PMID 7862637 DOI: 10.1073/Pnas.92.4.1077 |
0.416 |
|
| 1995 |
Hu Q, Milfay D, Williams LT. Binding of NCK to SOS and activation of ras-dependent gene expression. Molecular and Cellular Biology. 15: 1169-74. PMID 7862111 DOI: 10.1128/Mcb.15.3.1169 |
0.5 |
|
| 1995 |
Weng QP, Andrabi K, Klippel A, Kozlowski MT, Williams LT, Avruch J. Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 92: 5744-8. PMID 7777579 DOI: 10.1073/Pnas.92.12.5744 |
0.398 |
|
| 1995 |
Hu Q, Klippel A, Muslin AJ, Fantl WJ, Williams LT. Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. Science (New York, N.Y.). 268: 100-2. PMID 7701328 DOI: 10.1126/Science.7701328 |
0.762 |
|
| 1995 |
Koyama S, Williams LT, Kikuchi A. Characterization of the interaction of Raf-1 with ras p21 or 14-3-3 protein in intact cells. Febs Letters. 368: 321-5. PMID 7628630 DOI: 10.1016/0014-5793(95)00686-4 |
0.345 |
|
| 1995 |
Kavanaugh WM, Turck CW, Williams LT. PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine Science. 268: 1177-1179. PMID 7539155 DOI: 10.1126/Science.7539155 |
0.341 |
|
| 1995 |
Morishita K, Johnson DE, Williams LT. A novel promoter for vascular endothelial growth factor receptor (flt-1) that confers endothelial-specific gene expression. The Journal of Biological Chemistry. 270: 27948-53. PMID 7499271 DOI: 10.1074/Jbc.270.46.27948 |
0.377 |
|
| 1995 |
Li G, D'Souza-Schorey C, Barbieri MA, Roberts RL, Klippel A, Williams LT, Stahl PD. Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5. Proceedings of the National Academy of Sciences of the United States of America. 92: 10207-11. PMID 7479754 DOI: 10.1073/Pnas.92.22.10207 |
0.428 |
|
| 1994 |
Muslin AJ, Peters KG, Williams LT. Direct activation of phospholipase C-γ by fibroblast growth factor receptor is not required for mesoderm induction in Xenopus animal caps Molecular and Cellular Biology. 14: 3006-3012. PMID 8164656 DOI: 10.1128/mcb.14.5.3006-3012.1994 |
0.769 |
|
| 1994 |
Shilling FM, Carroll DJ, Muslin AJ, Escobedo JA, Williams LT, Jaffe LA. Evidence for both tyrosine kinase and G-protein-coupled pathways leading to starfish egg activation. Developmental Biology. 162: 590-9. PMID 8150217 DOI: 10.1006/Dbio.1994.1112 |
0.781 |
|
| 1994 |
Klippel A, Escobedo JA, Hirano M, Williams LT. The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity Molecular and Cellular Biology. 14: 2675-2685. PMID 8139567 DOI: 10.1128/Mcb.14.4.2675 |
0.338 |
|
| 1994 |
Kundra V, Escobedo JA, Kazlauskas A, Kim HK, Rhee SG, Williams LT, Zetter BR. Regulation of chemotaxis by the platelet-derived growth factor receptor-beta. Nature. 367: 474-6. PMID 8107807 DOI: 10.1038/367474A0 |
0.487 |
|
| 1994 |
Clyman RI, Peters KG, Chen YQ, Escobedo J, Williams LT, Ives HE, Wilson E. Phospholipase C gamma activation, phosphotidylinositol hydrolysis, and calcium mobilization are not required for FGF receptor-mediated chemotaxis. Cell Adhesion and Communication. 1: 333-42. PMID 8081884 DOI: 10.3109/15419069409097264 |
0.456 |
|
| 1994 |
Shinbrot E, Peters KG, Williams LT. Expression of the platelet-derived growth factor β receptor during organogenesis and tissue differentiation in the mouse embryo Developmental Dynamics. 199: 169-175. PMID 8018985 DOI: 10.1002/Aja.1001990302 |
0.38 |
|
| 1994 |
Fantl WJ, Muslin AJ, Kikuchi A, Martin JA, MacNicol AM, Gross RW, Williams LT. Activation of Raf-1 by 14-3-3 proteins. Nature. 371: 612-4. PMID 7935795 DOI: 10.1038/371612A0 |
0.654 |
|
| 1994 |
Kikuchi A, Demo SD, Ye ZH, Chen YW, Williams LT. ralGDS family members interact with the effector loop of ras p21. Molecular and Cellular Biology. 14: 7483-91. PMID 7935463 DOI: 10.1128/Mcb.14.11.7483 |
0.321 |
|
| 1994 |
Peters K, Werner S, Liao X, Wert S, Whitsett J, Williams L. Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. The Embo Journal. 13: 3296-3301. DOI: 10.1002/J.1460-2075.1994.Tb06631.X |
0.3 |
|
| 1993 |
Peters K, Ornitz D, Werner S, Williams L. Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis. Developmental Biology. 155: 423-30. PMID 8432397 DOI: 10.1006/Dbio.1993.1040 |
0.367 |
|
| 1993 |
Johnson DE, Williams LT. Structural and functional diversity in the FGF receptor multigene family Advances in Cancer Research. 60: 1-41. PMID 8417497 DOI: 10.1016/S0065-230X(08)60821-0 |
0.374 |
|
| 1993 |
Muslin AJ, Klippel A, Williams LT. Phosphatidylinositol 3-kinase activity is important for progesterone- induced Xenopus oocyte maturation Molecular and Cellular Biology. 13: 6661-6666. PMID 8413262 DOI: 10.1128/mcb.13.11.6661-6666.1993 |
0.762 |
|
| 1993 |
Klippel A, Escobedo JA, Hu Q, Williams LT. A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3- kinase binds the 110-kDa catalytic subunit in vivo Molecular and Cellular Biology. 13: 5560-5566. PMID 8395006 DOI: 10.1128/Mcb.13.9.5560 |
0.406 |
|
| 1993 |
Satoh T, Fantl WJ, Escobedo JA, Williams LT, Kaziro Y. Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types. Molecular and Cellular Biology. 13: 3706-13. PMID 8388543 DOI: 10.1128/Mcb.13.6.3706 |
0.462 |
|
| 1993 |
Quinn TP, Peters KG, De Vries C, Ferrara N, Williams LT. Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium Proceedings of the National Academy of Sciences of the United States of America. 90: 7533-7537. PMID 8356051 DOI: 10.1073/Pnas.90.16.7533 |
0.392 |
|
| 1993 |
Muslin AJ, MacNicol AM, Williams LT. Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos Molecular and Cellular Biology. 13: 4197-4202. PMID 8321223 DOI: 10.1128/mcb.13.7.4197-4202.1993 |
0.751 |
|
| 1993 |
Peters KG, De Vries C, Williams LT. Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth Proceedings of the National Academy of Sciences of the United States of America. 90: 8915-8919. PMID 7692439 DOI: 10.1073/Pnas.90.19.8915 |
0.336 |
|
| 1993 |
Fantl WJ, Johnson DE, Williams LT. Signalling by receptor tyrosine kinases Annual Review of Biochemistry. 62: 453-481. PMID 7688944 DOI: 10.1146/Annurev.Bi.62.070193.002321 |
0.44 |
|
| 1993 |
MacNicol AM, Muslin AJ, Williams LT. Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF Cell. 73: 571-583. PMID 7683975 DOI: 10.1016/0092-8674(93)90143-E |
0.762 |
|
| 1993 |
Werner S, Weinberg W, Liao X, Peters KG, Blessing M, Yuspa SH, Weiner RL, Williams LT. Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation. The Embo Journal. 12: 2635-2643. DOI: 10.1002/J.1460-2075.1993.Tb05924.X |
0.405 |
|
| 1992 |
Pazin MJ, Williams LT. Triggering signaling cascades by receptor tyrosine kinases Trends in Biochemical Sciences. 17: 374-378. PMID 1455504 DOI: 10.1016/0968-0004(92)90003-R |
0.432 |
|
| 1992 |
Werner S, Peters KG, Longaker MT, Fuller-Pace F, Banda MJ, Williams LT. Large induction of keratinocyte growth factor expression in the dermis during wound healing. Proceedings of the National Academy of Sciences of the United States of America. 89: 6896-900. PMID 1379725 DOI: 10.1073/Pnas.89.15.6896 |
0.333 |
|
| 1992 |
Peters KG, Marie J, Wilson E, Ives HE, Escobedo J, Rosario MD, Mirda D, Williams LT. Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis Nature. 358: 678-681. PMID 1379697 DOI: 10.1038/358678A0 |
0.472 |
|
| 1992 |
Fantl WJ, Escobedo JA, Martin GA, Turck CW, del Rosario M, McCormick F, Williams LT. Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways Cell. 69: 413-423. PMID 1374684 DOI: 10.1016/0092-8674(92)90444-H |
0.484 |
|
| 1992 |
Peters KG, Escobedo JA, Fantl WJ, Williams LT. Interactions of PDGF and FGF receptors with cytoplasmic signaling molecules Cold Spring Harbor Symposia On Quantitative Biology. 57: 63-66. PMID 1339700 DOI: 10.1101/Sqb.1992.057.01.008 |
0.369 |
|
| 1992 |
Kavanaugh WM, Klippel A, Escobedo JA, Williams LT. Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells Molecular and Cellular Biology. 12: 3415-3424. PMID 1321334 DOI: 10.1128/Mcb.12.8.3415 |
0.481 |
|
| 1992 |
Klippel A, Escobedo JA, Fantl WJ, Williams LT. The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor β receptor Molecular and Cellular Biology. 12: 1451-1459. PMID 1312663 DOI: 10.1128/Mcb.12.4.1451 |
0.476 |
|
| 1992 |
De Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor Science. 255: 989-991. PMID 1312256 DOI: 10.1126/Science.1312256 |
0.408 |
|
| 1992 |
Werner S, Duan DSR, De Vries C, Peters KG, Johnson DE, Williams LT. Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities Molecular and Cellular Biology. 12: 82-88. PMID 1309595 DOI: 10.1128/Mcb.12.1.82 |
0.431 |
|
| 1992 |
Mirda DP, Navarro D, Paz P, Lee PL, Pereira L, Williams LT. The fibroblast growth factor receptor is not required for herpes simplex virus type 1 infection Journal of Virology. 66: 448-457. PMID 1309254 DOI: 10.1128/Jvi.66.1.448-457.1992 |
0.381 |
|
| 1992 |
Williams LT, Escobedo JA, Fantl WJ, de Vries C, Klippel A. Receptors for platelet-derived growth factor and vascular endothelial growth factor Journal of Molecular and Cellular Cardiology. 24: 38. DOI: 10.1016/0022-2828(92)90145-P |
0.329 |
|
| 1991 |
Ueno H, Colbert H, Escobedo JA, Williams LT. Inhibition of PDGF β receptor signal transduction by coexpression of a truncated receptor Science. 252: 844-848. PMID 1851331 DOI: 10.1126/Science.1851331 |
0.436 |
|
| 1991 |
Escobedo JA, Navankasattusas S, Kavanaugh WM, Milfay D, Fried VA, Williams LT. cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor Cell. 65: 75-82. PMID 1849460 DOI: 10.1016/0092-8674(91)90409-R |
0.482 |
|
| 1991 |
Escobedo JA, Kaplan DR, Kavanaugh WM, Turck CW, Williams LT. A Phosphatidylinositol-3 Kinase Binds to Platelet-Derived Growth Factor Receptors through a Specific Receptor Sequence Containing Phosphotyrosine Molecular and Cellular Biology. 11: 1125-1132. PMID 1703628 DOI: 10.1128/Mcb.11.2.1125 |
0.495 |
|
| 1991 |
Williams LT, Escobedo JA, Fantl WJ, Turck CW, Klippel A. Interactions of growth factor receptors with cytoplasmic signaling molecules Cold Spring Harbor Symposia On Quantitative Biology. 56: 243-250. PMID 1668083 DOI: 10.1101/Sqb.1991.056.01.030 |
0.466 |
|
| 1991 |
Johnson DE, Lu J, Chen H, Werner S, Williams LT. The human fibroblast growth factor receptor genes: A common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain Molecular and Cellular Biology. 11: 4627-4634. PMID 1652059 DOI: 10.1128/Mcb.11.9.4627 |
0.416 |
|
| 1990 |
Johnson DE, Lee PL, Lu J, Williams LT. Diverse forms of a receptor for acidic and basic fibroblast growth factors Molecular and Cellular Biology. 10: 4728-4736. PMID 2167437 DOI: 10.1128/Mcb.10.9.4728 |
0.392 |
|
| 1990 |
Harsh GR, Keating MT, Escobedo JA, Williams LT. Platelet derived growth factor (PDGF) autocrine components in human tumor cell lines. Journal of Neuro-Oncology. 8: 1-12. PMID 2156959 DOI: 10.1007/Bf00182081 |
0.393 |
|
| 1990 |
Kaplan DR, Morrison DK, Wong G, McCormick F, Williams LT. PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex Cell. 61: 125-133. PMID 2156626 DOI: 10.1016/0092-8674(90)90220-9 |
0.508 |
|
| 1989 |
Escobedo JA, Barr PJ, Williams LT. Role of tyrosine kinase and membrane-spanning domains in signal transduction by the platelet-derived growth factor receptor. Molecular and Cellular Biology. 8: 5126-31. PMID 2854192 DOI: 10.1128/Mcb.8.12.5126 |
0.503 |
|
| 1989 |
Vu TH, Martin GR, Lee P, Mark D, Wang A, Williams LT. Developmentally regulated use of alternative promoters creates a novel platelet-derived growth factor receptor transcript in mouse teratocarcinoma and embryonic stem cells Molecular and Cellular Biology. 9: 4563-4567. PMID 2573835 DOI: 10.1128/Mcb.9.10.4563 |
0.393 |
|
| 1989 |
Harsh IV GR, Rosenblum ML, Williams LT. Oncogene-related growth factors and growth factor receptors in human malignant glioma-derived cell lines Journal of Neuro-Oncology. 7: 47-56. PMID 2547033 DOI: 10.1007/Bf00149378 |
0.42 |
|
| 1989 |
Lee PL, Johnson DE, Cousens LS, Fried VA, Williams LT. Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor. Science (New York, N.Y.). 245: 57-60. PMID 2544996 DOI: 10.1126/Science.2544996 |
0.409 |
|
| 1989 |
Williams LT. Signal transduction by the platelet-derived growth factor receptor. Science (New York, N.Y.). 243: 1564-70. PMID 2538922 DOI: 10.1126/Science.2538922 |
0.461 |
|
| 1989 |
Fantl WJ, Escobedo JA, Williams LT. Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis. Molecular and Cellular Biology. 9: 4473-8. PMID 2479827 DOI: 10.1128/Mcb.9.10.4473 |
0.459 |
|
| 1989 |
Morrison DK, Kaplan DR, Escobedo JA, Rapp UR, Roberts TM, Williams LT. Direct activation of the serine/threonine kinase activity of raf-1 through tyrosine phosphorylation by the PDGF β-receptor Cell. 58: 649-657. PMID 2475255 DOI: 10.1016/0092-8674(89)90100-1 |
0.499 |
|
| 1989 |
Coughlin SR, Escobedo JA, Williams LT. Role of phosphatidylinositol kinase in PDGF receptor signal transduction. Science (New York, N.Y.). 243: 1191-4. PMID 2466336 DOI: 10.1126/Science.2466336 |
0.502 |
|
| 1988 |
Williams LT, Escobedo JA, Keating MT, Coughlin SR. Signal transduction by the platelet-derived growth factor receptor. Cold Spring Harbor Symposia On Quantitative Biology. 53: 455-65. PMID 2855486 DOI: 10.1101/Sqb.1988.053.01.053 |
0.38 |
|
| 1988 |
Escobedo JA, Williams LT. A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF. Nature. 335: 85-7. PMID 2842689 DOI: 10.1038/335085A0 |
0.502 |
|
| 1988 |
Kavanaugh WM, Williams LT, Ives HE, Coughlin SR. Serotonin-induced deoxyribonucleic acid synthesis in vascular smooth muscle cells involves a novel, pertussis toxin-sensitive pathway. Molecular Endocrinology (Baltimore, Md.). 2: 599-605. PMID 2842665 DOI: 10.1210/Mend-2-7-599 |
0.357 |
|
| 1988 |
Kacich RL, Williams LT, Coughlin SR. Arachidonic acid and cyclic adenosine monophosphate stimulation of c-fos expression by a pathway independent of phorbol ester-sensitive protein kinase C. Molecular Endocrinology (Baltimore, Md.). 2: 73-7. PMID 2840568 DOI: 10.1210/Mend-2-1-73 |
0.445 |
|
| 1988 |
Escobedo JA, Navankasatussas S, Cousens LS, Coughlin SR, Bell GI, Williams LT. A common PDGF receptor is activated by homodimeric A and B forms of PDGF. Science (New York, N.Y.). 240: 1532-4. PMID 2836953 DOI: 10.1126/Science.2836953 |
0.469 |
|
| 1988 |
Keating MT, Williams LT. Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cells. Science (New York, N.Y.). 239: 914-6. PMID 2829358 DOI: 10.1126/Science.2829358 |
0.415 |
|
| 1988 |
Taylor RN, Williams LT. Developmental expression of platelet-derived growth factor and its receptor in the human placenta. Molecular Endocrinology (Baltimore, Md.). 2: 627-32. PMID 2457800 DOI: 10.1210/Mend-2-7-627 |
0.389 |
|
| 1987 |
KEATING M, WILLIAMS L. Platelet-derived growth factor receptor biosynthesis and degradation Journal of Molecular and Cellular Cardiology. 19: S3-S3. DOI: 10.1016/S0022-2828(87)80632-6 |
0.363 |
|
| 1986 |
Letterio JJ, Coughlin SR, Williams LT. Pertussis toxin-sensitive pathway in the stimulation of c-myc expression and DNA synthesis by bombesin. Science (New York, N.Y.). 234: 1117-9. PMID 3465038 DOI: 10.1126/Science.3465038 |
0.401 |
|
| 1986 |
Starksen NF, Simpson PC, Bishopric N, Coughlin SR, Lee WM, Escobedo JA, Williams LT. Cardiac myocyte hypertrophy is associated with c-myc protooncogene expression Proceedings of the National Academy of Sciences of the United States of America. 83: 8348-8350. PMID 3022291 DOI: 10.1073/Pnas.83.21.8348 |
0.606 |
|
| 1986 |
King CR, Kraus MH, Williams LT, Merlino GT, Pastan IH, Aaronson SA. Human tumor cell lines with EGF receptor gene amplification in the absence of aberrant sized mRNAs. Nucleic Acids Research. 13: 8477-86. PMID 3001641 DOI: 10.1093/Nar/13.23.8477 |
0.505 |
|
| 1986 |
Coughlin SR, Lee WM, Williams PW, Giels GM, Williams LT. c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF. Cell. 43: 243-51. PMID 3000601 DOI: 10.1016/0092-8674(85)90029-7 |
0.406 |
|
| 1985 |
Garrett JS, Coughlin SR, Niman HL, Tremble PM, Giels GM, Williams LT. Blockade of autocrine stimulation in simian sarcoma virus-transformed cells reverses down-regulation of platelet-derived growth factor receptors. Proceedings of the National Academy of Sciences of the United States of America. 81: 7466-70. PMID 6095298 DOI: 10.1073/Pnas.81.23.7466 |
0.426 |
|
| 1985 |
Leal F, Williams LT, Robbins KC, Aaronson SA. Evidence that the v-sis gene product transforms by interaction with the receptor for platelet-derived growth factor. Science (New York, N.Y.). 230: 327-30. PMID 2996133 DOI: 10.1126/Science.2996133 |
0.404 |
|
| 1983 |
Williams LT, Antoniades HN, Goetzl EJ. Platelet-derived growth factor stimulates mouse 3T3 cell mitogenesis and leukocyte chemotaxis through different structural determinants. The Journal of Clinical Investigation. 72: 1759-63. PMID 6630524 DOI: 10.1172/Jci111135 |
0.35 |
|
| 1983 |
Williams LT, Tremble P, Antoniades HN. Platelet-derived growth factor binds specifically to receptors on vascular smooth muscle cells and the binding becomes nondissociable. Proceedings of the National Academy of Sciences of the United States of America. 79: 5867-70. PMID 6310551 DOI: 10.1073/Pnas.79.19.5867 |
0.357 |
|
| 1979 |
McConnaughey MM, Jones LR, Watanabe AM, Besch HR, Williams LT, Lefkowitz RJ. Thyroxine and propylthiouracil effects on alpha- and beta-adrenergic receptor number, ATPase activities, and sialic acid content of rat cardiac membrane vesicles. Journal of Cardiovascular Pharmacology. 1: 609-23. PMID 94627 DOI: 10.1097/00005344-197911000-00002 |
0.46 |
|
| 1978 |
Lefkowitz RJ, Limbird LE, Williams LT, Wessels M. Beta-adrenergic receptors: regulatory role of agonists. Journal of Supramolecular Structure. 8: 501-10. PMID 31515 DOI: 10.1002/Jss.400080412 |
0.737 |
|
| 1977 |
Williams LT, Snyderman R, Pike MC, Lefkowitz RJ. Specific receptor sites for chemotactic peptides on human polymorphonuclear leukocytes. Proceedings of the National Academy of Sciences of the United States of America. 74: 1204-8. PMID 265563 DOI: 10.1073/Pnas.74.3.1204 |
0.435 |
|
| 1977 |
Williams LT, Lefkowitz RJ. Regulation of rabbit myometrial alpha adrenergic receptors by estrogen and progesterone. The Journal of Clinical Investigation. 60: 815-8. PMID 197125 DOI: 10.1172/Jci108835 |
0.487 |
|
| 1977 |
Lefkowitz RJ, Williams LT. Catecholamine binding to the beta-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 74: 515-9. PMID 15249 DOI: 10.1073/Pnas.74.2.515 |
0.507 |
|
| 1976 |
Williams LT, Snyderman R, Lefkowitz RJ. Identification of beta-adrenergic receptors in human lymphocytes by (-) (3H) alprenolol binding. The Journal of Clinical Investigation. 57: 149-55. PMID 1245597 DOI: 10.1172/Jci108254 |
0.501 |
|
| 1975 |
Alexander RW, Williams LT, Lefkowitz RJ. Identification of cardiac beta-adrenergic receptors by (minus) [3H]alprenolol binding. Proceedings of the National Academy of Sciences of the United States of America. 72: 1564-8. PMID 1055427 DOI: 10.1073/Pnas.72.4.1564 |
0.572 |
|
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