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Jijie Chai, Ph.D. - Publications

Affiliations: 
School of Life Sciences Tsinghua National University, Beijing, Beijing Shi, China 
Website:
http://life.tsinghua.edu.cn/english/faculty/faculty/721.html

97 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ma S, An C, Lawson AW, Cao Y, Sun Y, Tan EYJ, Pan J, Jirschitzka J, Kümmel F, Mukhi N, Han Z, Feng S, Wu B, Schulze-Lefert P, Chai J. Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR. Nature. PMID 38866053 DOI: 10.1038/s41586-024-07668-7  0.355
2024 Song W, Liu L, Yu D, Bernardy H, Jirschitzka J, Huang S, Jia A, Jemielniak W, Acker J, Laessle H, Wang J, Shen Q, Chen W, Li P, Parker JE, ... ... Chai J, et al. Substrate-induced condensation activates plant TIR domain proteins. Nature. PMID 38480885 DOI: 10.1038/s41586-024-07183-9  0.353
2024 Xiao Y, Sun G, Yu Q, Gao T, Zhu Q, Wang R, Huang S, Han Z, Cervone F, Yin H, Qi T, Wang Y, Chai J. A plant mechanism of hijacking pathogen virulence factors to trigger innate immunity. Science (New York, N.Y.). 383: 732-739. PMID 38359129 DOI: 10.1126/science.adj9529  0.316
2023 Wu Y, Sun Y, Richet E, Han Z, Chai J. Structural basis for negative regulation of the Escherichia coli maltose system. Nature Communications. 14: 4925. PMID 37582800 DOI: 10.1038/s41467-023-40447-y  0.386
2022 Sun Y, Wang Y, Zhang X, Chen Z, Xia Y, Wang L, Sun Y, Zhang M, Xiao Y, Han Z, Wang Y, Chai J. Plant receptor-like protein activation by a microbial glycoside hydrolase. Nature. PMID 36131021 DOI: 10.1038/s41586-022-05214-x  0.334
2021 Huang M, Zhang X, Toh GA, Gong Q, Wang J, Han Z, Wu B, Zhong F, Chai J. Structural and biochemical mechanisms of NLRP1 inhibition by DPP9. Nature. PMID 33731929 DOI: 10.1038/s41586-021-03320-w  0.407
2020 Ma S, Lapin D, Liu L, Sun Y, Song W, Zhang X, Logemann E, Yu D, Wang J, Jirschitzka J, Han Z, Schulze-Lefert P, Parker JE, Chai J. Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme. Science (New York, N.Y.). 370. PMID 33273071 DOI: 10.1126/science.abe3069  0.335
2020 Sun L, Peng Y, Yu W, Zhang Y, Liang L, Song C, Hou J, Qiao Y, Wang Q, Chen J, Wu M, Zhang D, Li E, Han Z, Zhao Q, ... ... Chai J, et al. Mechanistic insight into antiretroviral potency of 2'-deoxy-2'-β-fluoro-4'-azidocytidine (FNC) with a long-lasting effect on HIV-1 prevention. Journal of Medicinal Chemistry. PMID 32678592 DOI: 10.1021/Acs.Jmedchem.0C00940  0.438
2020 Wang J, Chai J. Molecular actions of NLR immune receptors in plants and animals. Science China. Life Sciences. PMID 32613490 DOI: 10.1007/S11427-019-1687-6  0.313
2020 Huang Z, Chai J. Door to the cell for COVID-19 opened, leading way to therapies. Signal Transduction and Targeted Therapy. 5: 104. PMID 32591496 DOI: 10.1038/s41392-020-00215-6  0.346
2019 Yang X, Lin G, Han Z, Chai J. Structural Biology of NOD-Like Receptors. Advances in Experimental Medicine and Biology. 1172: 119-141. PMID 31628654 DOI: 10.1007/978-981-13-9367-9_6  0.467
2019 Xiao Y, Stegmann M, Han Z, DeFalco TA, Parys K, Xu L, Belkhadir Y, Zipfel C, Chai J. Mechanisms of RALF peptide perception by a heterotypic receptor complex. Nature. PMID 31291642 DOI: 10.1038/S41586-019-1409-7  0.421
2019 Wang J, Hu M, Wang J, Qi J, Han Z, Wang G, Qi Y, Wang HW, Zhou JM, Chai J. Reconstitution and structure of a plant NLR resistosome conferring immunity. Science (New York, N.Y.). 364. PMID 30948527 DOI: 10.1126/Science.Aav5870  0.448
2019 Wang J, Wang J, Hu M, Wu S, Qi J, Wang G, Han Z, Qi Y, Gao N, Wang HW, Zhou JM, Chai J. Ligand-triggered allosteric ADP release primes a plant NLR complex. Science (New York, N.Y.). 364. PMID 30948526 DOI: 10.2210/Pdb6J5U/Pdb  0.425
2018 Wang R, Han Z, Liu B, Zhou B, Wang N, Jiang Q, Qiao Y, Song C, Chai J, Chang J. Identification of Natural Compound Radicicol as a Potent FTO Inhibitor. Molecular Pharmaceutics. PMID 30063141 DOI: 10.1021/Acs.Molpharmaceut.8B00522  0.374
2018 Liang X, Ma M, Zhou Z, Wang J, Yang X, Rao S, Bi G, Li L, Zhang X, Chai J, Chen S, Zhou JM. Ligand-triggered de-repression of Arabidopsis heterotrimeric G proteins coupled to immune receptor kinases. Cell Research. PMID 29545645 DOI: 10.1038/S41422-018-0027-5  0.347
2018 Han Z, Xiao Y, Song W, Wang J, Lin G, Zhang X, Chai J. Structural and functional studies of plant receptor kinases Chinese Science Bulletin. 63: 2921-2931. DOI: 10.1360/N972018-00412  0.431
2017 Wu Z, Liang S, Song W, Lin G, Wang W, Zhang H, Han Z, Chai J. Functional and Structural Characterization of a Receptor-Like Kinase Involved in Germination and Cell Expansion in Arabidopsis. Frontiers in Plant Science. 8: 1999. PMID 29213277 DOI: 10.3389/Fpls.2017.01999  0.379
2017 Yang X, Yang F, Wang W, Lin G, Hu Z, Han Z, Qi Y, Zhang L, Wang J, Sui SF, Chai J. Structural basis for specific flagellin recognition by the NLR protein NAIP5. Cell Research. PMID 29182158 DOI: 10.1038/Cr.2017.148  0.462
2017 Zhang X, Liu W, Nagae TT, Takeuchi H, Zhang H, Han Z, Higashiyama T, Chai J. Structural basis for receptor recognition of pollen tube attraction peptides. Nature Communications. 8: 1331. PMID 29109411 DOI: 10.1038/S41467-017-01323-8  0.372
2017 Mou S, Zhang X, Han Z, Wang J, Gong X, Chai J. CLE42 binding induces PXL2 interaction with SERK2. Protein & Cell. PMID 28677102 DOI: 10.1007/S13238-017-0435-1  0.379
2017 Lin G, Zhang L, Han Z, Yang X, Liu W, Li E, Chang J, Qi Y, Shpak ED, Chai J. A receptor-like protein acts as a specificity switch for the regulation of stomatal development. Genes & Development. PMID 28536146 DOI: 10.2210/Pdb5Xjx/Pdb  0.401
2016 Ma R, Han Z, Hu Z, Lin G, Gong X, Zhang H, Nasrallah JB, Chai J. Structural basis for specific self-incompatibility response in Brassica. Cell Research. PMID 27824028 DOI: 10.1038/Cr.2016.129  0.406
2016 Song W, Han Z, Wang J, Lin G, Chai J. Structural insights into ligand recognition and activation of plant receptor kinases. Current Opinion in Structural Biology. 43: 18-27. PMID 27750059 DOI: 10.1016/J.Sbi.2016.09.012  0.404
2016 Zhang H, Han Z, Song W, Chai J. Structural insight into recognition of plant peptide hormones by receptors. Molecular Plant. PMID 27743937 DOI: 10.1016/J.Molp.2016.10.002  0.331
2016 Hu Z, Chai J. Structural Mechanisms in NLR Inflammasome Assembly and Signaling. Current Topics in Microbiology and Immunology. 397: 23-42. PMID 27460803 DOI: 10.1007/978-3-319-41171-2_2  0.512
2016 Zhang H, Lin X, Han Z, Wang J, Qu LJ, Chai J. SERK Family Receptor-Like Kinases Function as a Co-receptor with PXY for Plant Vascular Development. Molecular Plant. PMID 27449136 DOI: 10.1016/J.Molp.2016.07.004  0.354
2016 Liu S, Wang J, Han Z, Gong X, Zhang H, Chai J. Molecular Mechanism for Fungal Cell Wall Recognition by Rice Chitin Receptor OsCEBiP. Structure (London, England : 1993). PMID 27238968 DOI: 10.1016/J.Str.2016.04.014  0.442
2016 Song W, Liu L, Wang J, Wu Z, Zhang H, Tang J, Lin G, Wang Y, Wen X, Li W, Han Z, Guo H, Chai J. Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth. Cell Research. PMID 27229311 DOI: 10.1038/Cr.2016.62  0.366
2016 Zhang H, Lin X, Han Z, Qu LJ, Chai J. Crystal structure of PXY-TDIF complex reveals a conserved recognition mechanism among CLE peptide-receptor pairs. Cell Research. PMID 27055373 DOI: 10.1038/Cr.2016.45  0.385
2016 Qiao Y, Zhou B, Zhang M, Liu W, Han Z, Song C, Yu W, Yang Q, Wang R, Wang S, Shi S, Zhao R, Chai J, Chang J. A Novel Inhibitor of the Obesity-Related Protein FTO. Biochemistry. PMID 26915401 DOI: 10.1021/Acs.Biochem.6B00023  0.303
2016 Meng X, Zhou J, Tang J, Li B, de Oliveira MV, Chai J, He P, Shan L. Ligand-Induced Receptor-like Kinase Complex Regulates Floral Organ Abscission in Arabidopsis. Cell Reports. PMID 26854226 DOI: 10.1016/J.Celrep.2016.01.023  0.354
2016 Yan X, Shi Y, Kou B, Zhu Z, Chai J, Chen D, Guo H. [Keratin 18 phosphorylation increases autophagy of colorectal cancer HCT116 cells and enhanced its sensitivity to oxaliplatin]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 32: 34-8. PMID 26728375  0.371
2015 Albert I, Böhm H, Albert M, Feiler CE, Imkampe J, Wallmeroth N, Brancato C, Raaymakers TM, Oome S, Zhang H, Krol E, Grefen C, Gust AA, Chai J, Hedrich R, et al. An RLP23-SOBIR1-BAK1 complex mediates NLP-triggered immunity. Nature Plants. 1: 15140. PMID 27251392 DOI: 10.1038/Nplants.2015.140  0.356
2015 Wang J, Chai J, Wang H. Structure of the mouse toll-like receptor 13 ectodomain in complex with a conserved sequence from bacterial 23S ribosomal RNA. The Febs Journal. PMID 26676765 DOI: 10.1111/Febs.13628  0.306
2015 Hu Z, Zhou Q, Zhang C, Fan S, Cheng W, Zhao Y, Shao F, Wang HW, Sui SF, Chai J. Structural and biochemical basis for induced self-propagation of NLRC4. Science (New York, N.Y.). PMID 26449475 DOI: 10.1126/Science.Aac5489  0.449
2015 Song W, Wang J, Han Z, Zhang Y, Zhang H, Wang W, Chang J, Xia B, Fan S, Zhang D, Wang J, Wang HW, Chai J. Structural basis for specific recognition of single-stranded RNA by Toll-like receptor 13. Nature Structural & Molecular Biology. PMID 26323037 DOI: 10.1038/Nsmb.3080  0.302
2015 He W, Zhou B, Liu W, Zhang M, Shen Z, Han Z, Jiang Q, Yang Q, Song C, Wang R, Niu T, Han S, Zhang L, Wu J, Guo F, ... ... Chai J, et al. Identification of A Novel Small-Molecule Binding Site of the Fat Mass and Obesity Associated Protein (FTO). Journal of Medicinal Chemistry. PMID 26314339 DOI: 10.1021/Acs.Jmedchem.5B00702  0.305
2015 Wang J, Li H, Han Z, Zhang H, Wang T, Lin G, Chang J, Yang W, Chai J. Allosteric receptor activation by the plant peptide hormone phytosulfokine. Nature. PMID 26308901 DOI: 10.1038/Nature14858  0.442
2015 Tang J, Han Z, Sun Y, Zhang H, Gong X, Chai J. Structural basis for recognition of an endogenous peptide by the plant receptor kinase PEPR1. Cell Research. 25: 110-20. PMID 25475059 DOI: 10.1038/Cr.2014.161  0.456
2014 Han Z, Sun Y, Chai J. Structural insight into the activation of plant receptor kinases. Current Opinion in Plant Biology. 20: 55-63. PMID 24840292 DOI: 10.1016/J.Pbi.2014.04.008  0.404
2014 Song W, Han Z, Sun Y, Chai J. Crystal structure of a plant leucine rich repeat protein with two island domains. Science China. Life Sciences. 57: 137-44. PMID 24369349 DOI: 10.1007/S11427-013-4586-X  0.444
2014 Chai J, Shi Y. Apoptosome and inflammasome: Conserved machineries for caspase activation National Science Review. 1: 101-118. DOI: 10.1093/Nsr/Nwt025  0.639
2013 Hao W, Collier SM, Moffett P, Chai J. Structural basis for the interaction between the potato virus X resistance protein (Rx) and its cofactor Ran GTPase-activating protein 2 (RanGAP2). The Journal of Biological Chemistry. 288: 35868-76. PMID 24194517 DOI: 10.1074/Jbc.M113.517417  0.429
2013 Sun Y, Han Z, Tang J, Hu Z, Chai C, Zhou B, Chai J. Structure reveals that BAK1 as a co-receptor recognizes the BRI1-bound brassinolide. Cell Research. 23: 1326-9. PMID 24126715 DOI: 10.1038/Cr.2013.131  0.312
2013 Sun Y, Li L, Macho AP, Han Z, Hu Z, Zipfel C, Zhou JM, Chai J. Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex. Science (New York, N.Y.). 342: 624-8. PMID 24114786 DOI: 10.1126/Science.1243825  0.433
2013 Chai C, Yu Y, Zhuo W, Zhao H, Li X, Wang N, Chai J, Yang M. Structural basis for a homodimeric ATPase subunit of an ECF transporter. Protein & Cell. 4: 793-801. PMID 24104393 DOI: 10.1007/S13238-013-3915-Y  0.372
2013 Hu Z, Yan C, Liu P, Huang Z, Ma R, Zhang C, Wang R, Zhang Y, Martinon F, Miao D, Deng H, Wang J, Chang J, Chai J. Crystal structure of NLRC4 reveals its autoinhibition mechanism. Science (New York, N.Y.). 341: 172-5. PMID 23765277 DOI: 10.1126/Science.1236381  0.6
2013 She J, Han Z, Zhou B, Chai J. Structural basis for differential recognition of brassinolide by its receptors. Protein & Cell. 4: 475-82. PMID 23709366 DOI: 10.1007/S13238-013-3027-8  0.382
2013 Xu C, Li M, Wu J, Guo H, Li Q, Zhang Y, Chai J, Li T, Xue Y. Identification of a canonical SCF(SLF) complex involved in S-RNase-based self-incompatibility of Pyrus (Rosaceae). Plant Molecular Biology. 81: 245-57. PMID 23263858 DOI: 10.1007/S11103-012-9995-X  0.313
2013 Liu P, Hu Z, Zhou B, Liu S, Chai J. Crystal structure of an LRR protein with two solenoids. Cell Research. 23: 303-5. PMID 23147790 DOI: 10.1038/Cr.2012.159  0.311
2012 Gao H, Wu X, Chai J, Han Z. Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region. Cell Research. 22: 1716-20. PMID 23147789 DOI: 10.1038/Cr.2012.156  0.366
2012 Yuan W, Wu T, Fu H, Dai C, Wu H, Liu N, Li X, Xu M, Zhang Z, Niu T, Han Z, Chai J, Zhou XJ, Gao S, Zhu B. Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation. Science (New York, N.Y.). 337: 971-5. PMID 22923582 DOI: 10.1126/Science.1225237  0.31
2012 Bai S, Liu J, Chang C, Zhang L, Maekawa T, Wang Q, Xiao W, Liu Y, Chai J, Takken FL, Schulze-Lefert P, Shen QH. Structure-function analysis of barley NLR immune receptor MLA10 reveals its cell compartment specific activity in cell death and disease resistance. Plos Pathogens. 8: e1002752. PMID 22685408 DOI: 10.1371/Journal.Ppat.1002752  0.42
2012 Liu T, Liu Z, Song C, Hu Y, Han Z, She J, Fan F, Wang J, Jin C, Chang J, Zhou JM, Chai J. Chitin-induced dimerization activates a plant immune receptor. Science (New York, N.Y.). 336: 1160-4. PMID 22654057 DOI: 10.1126/Science.1218867  0.438
2012 Cheng W, Yin K, Lu D, Li B, Zhu D, Chen Y, Zhang H, Xu S, Chai J, Gu L. Structural insights into a unique Legionella pneumophila effector LidA recognizing both GDP and GTP bound Rab1 in their active state. Plos Pathogens. 8: e1002528. PMID 22416225 DOI: 10.1371/Journal.Ppat.1002528  0.467
2011 Cheng W, Munkvold KR, Gao H, Mathieu J, Schwizer S, Wang S, Yan YB, Wang J, Martin GB, Chai J. Structural analysis of Pseudomonas syringae AvrPtoB bound to host BAK1 reveals two similar kinase-interacting domains in a type III Effector. Cell Host & Microbe. 10: 616-26. PMID 22169508 DOI: 10.1016/J.Chom.2011.10.013  0.448
2011 She J, Han Z, Kim TW, Wang J, Cheng W, Chang J, Shi S, Wang J, Yang M, Wang ZY, Chai J. Structural insight into brassinosteroid perception by BRI1. Nature. 474: 472-6. PMID 21666666 DOI: 10.1038/Nature10178  0.458
2011 Pei Q, Christofferson A, Zhang H, Chai J, Huang N. Computational investigation of the enzymatic mechanisms of phosphothreonine lyase. Biophysical Chemistry. 157: 16-23. PMID 21558045 DOI: 10.1016/J.Bpc.2011.04.002  0.324
2011 Maekawa T, Cheng W, Spiridon LN, Töller A, Lukasik E, Saijo Y, Liu P, Shen QH, Micluta MA, Somssich IE, Takken FL, Petrescu AJ, Chai J, Schulze-Lefert P. Coiled-coil domain-dependent homodimerization of intracellular barley immune receptors defines a minimal functional module for triggering cell death. Cell Host & Microbe. 9: 187-99. PMID 21402358 DOI: 10.1016/J.Chom.2011.02.008  0.389
2010 Huang Z, Chai J. Mapping the selection mechanisms by bacterial GEFs. Virulence. 1: 93-6. PMID 21178423 DOI: 10.4161/Viru.1.2.10617  0.492
2010 Chen D, Lei L, Flores R, Huang Z, Wu Z, Chai J, Zhong G. Autoprocessing and self-activation of the secreted protease CPAF in Chlamydia-infected cells. Microbial Pathogenesis. 49: 164-73. PMID 20510344 DOI: 10.1016/J.Micpath.2010.05.008  0.507
2010 Han Z, Niu T, Chang J, Lei X, Zhao M, Wang Q, Cheng W, Wang J, Feng Y, Chai J. Crystal structure of the FTO protein reveals basis for its substrate specificity. Nature. 464: 1205-9. PMID 20376003 DOI: 10.1038/Nature08921  0.39
2009 Huang Z, Sutton SE, Wallenfang AJ, Orchard RC, Wu X, Feng Y, Chai J, Alto NM. Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics. Nature Structural & Molecular Biology. 16: 853-60. PMID 19620963 DOI: 10.1038/Nsmb.1647  0.494
2009 Dong J, Xiao F, Fan F, Gu L, Cang H, Martin GB, Chai J. Crystal structure of the complex between Pseudomonas effector AvrPtoB and the tomato Pto kinase reveals both a shared and a unique interface compared with AvrPto-Pto. The Plant Cell. 21: 1846-59. PMID 19509331 DOI: 10.1105/Tpc.109.066878  0.47
2009 Chen D, Chai J, Hart PJ, Zhong G. Identifying catalytic residues in CPAF, a Chlamydia-secreted protease. Archives of Biochemistry and Biophysics. 485: 16-23. PMID 19388144 DOI: 10.1016/J.Abb.2009.01.014  0.398
2009 Liang P, Wang H, Chen H, Cui Y, Gu L, Chai J, Wang K. Structural Insights into KChIP4a Modulation of Kv4.3 Inactivation. The Journal of Biological Chemistry. 284: 4960-7. PMID 19109250 DOI: 10.1074/Jbc.M807704200  0.342
2008 Zong N, Xiang T, Zou Y, Chai J, Zhou JM. Blocking and triggering of plant immunity by Pseudomonas syringae effector AvrPto. Plant Signaling & Behavior. 3: 583-5. PMID 19704476 DOI: 10.4161/Psb.3.8.5741  0.326
2008 Huang Z, Feng Y, Chen D, Wu X, Huang S, Wang X, Xiao X, Li W, Huang N, Gu L, Zhong G, Chai J. Structural basis for activation and inhibition of the secreted chlamydia protease CPAF. Cell Host & Microbe. 4: 529-42. PMID 19064254 DOI: 10.1016/J.Chom.2008.10.005  0.592
2008 Ohlson MB, Huang Z, Alto NM, Blanc MP, Dixon JE, Chai J, Miller SI. Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. Cell Host & Microbe. 4: 434-46. PMID 18996344 DOI: 10.1016/J.Chom.2008.08.012  0.62
2008 Zhou JM, Chai J. Plant pathogenic bacterial type III effectors subdue host responses. Current Opinion in Microbiology. 11: 179-85. PMID 18372208 DOI: 10.1016/J.Mib.2008.02.004  0.303
2008 Xiang T, Zong N, Zou Y, Wu Y, Zhang J, Xing W, Li Y, Tang X, Zhu L, Chai J, Zhou JM. Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases. Current Biology : Cb. 18: 74-80. PMID 18158241 DOI: 10.1016/J.Cub.2007.12.020  0.524
2008 Chen L, Wang H, Zhang J, Gu L, Huang N, Zhou JM, Chai J. Structural basis for the catalytic mechanism of phosphothreonine lyase. Nature Structural & Molecular Biology. 15: 101-2. PMID 18084305 DOI: 10.1038/Nsmb1329  0.384
2007 Zhang J, Shao F, Li Y, Cui H, Chen L, Li H, Zou Y, Long C, Lan L, Chai J, Chen S, Tang X, Zhou JM. A Pseudomonas syringae effector inactivates MAPKs to suppress PAMP-induced immunity in plants. Cell Host & Microbe. 1: 175-85. PMID 18005697 DOI: 10.1016/J.Chom.2007.03.006  0.378
2007 Han Z, Xing X, Hu M, Zhang Y, Liu P, Chai J. Structural basis of EZH2 recognition by EED. Structure (London, England : 1993). 15: 1306-15. PMID 17937919 DOI: 10.1016/J.Str.2007.08.007  0.458
2007 Xing W, Zou Y, Liu Q, Liu J, Luo X, Huang Q, Chen S, Zhu L, Bi R, Hao Q, Wu JW, Zhou JM, Chai J. The structural basis for activation of plant immunity by bacterial effector protein AvrPto. Nature. 449: 243-7. PMID 17694048 DOI: 10.1038/Nature06109  0.679
2007 Wang H, Yan Y, Liu Q, Huang Y, Shen Y, Chen L, Chen Y, Yang Q, Hao Q, Wang K, Chai J. Structural basis for modulation of Kv4 K+ channels by auxiliary KChIP subunits. Nature Neuroscience. 10: 32-9. PMID 17187064 DOI: 10.1038/Nn1822  0.348
2006 Zhang T, Sun Y, Tian E, Deng H, Zhang Y, Luo X, Cai Q, Wang H, Chai J, Zhang H. RNA-binding proteins SOP-2 and SOR-1 form a novel PcG-like complex in C. elegans. Development (Cambridge, England). 133: 1023-33. PMID 16501168 DOI: 10.1242/Dev.02275  0.323
2005 Yan N, Chai J, Lee ES, Gu L, Liu Q, He J, Wu JW, Kokel D, Li H, Hao Q, Xue D, Shi Y. Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans. Nature. 437: 831-7. PMID 16208361 DOI: 10.1038/Nature04002  0.736
2004 Yan N, Gu L, Kokel D, Chai J, Li W, Han A, Chen L, Xue D, Shi Y. Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4. Molecular Cell. 15: 999-1006. PMID 15383288 DOI: 10.1016/J.Molcel.2004.08.022  0.681
2004 Yan N, Wu JW, Chai J, Li W, Shi Y. Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim. Nature Structural & Molecular Biology. 11: 420-8. PMID 15107838 DOI: 10.1038/Nsmb764  0.757
2003 Chai J, Yan N, Huh JR, Wu JW, Li W, Hay BA, Shi Y. Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination. Nature Structural Biology. 10: 892-8. PMID 14517550 DOI: 10.1038/Nsb989  0.749
2003 Chai J, Wu JW, Yan N, Massagué J, Pavletich NP, Shi Y. Features of a Smad3 MH1-DNA complex: Roles of water and zinc in DNA binding Journal of Biological Chemistry. 278: 20327-20331. PMID 12686552 DOI: 10.1074/Jbc.C300134200  0.748
2003 Shiozaki EN, Chai J, Rigotti DJ, Riedl SJ, Li P, Srinivasula SM, Alnemri ES, Fairman R, Shi Y. Mechanism of XIAP-mediated inhibition of caspase-9. Molecular Cell. 11: 519-27. PMID 12620238 DOI: 10.1016/S1097-2765(03)00054-6  0.811
2002 Wang X, Yang C, Chai J, Shi Y, Xue D. Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans. Science (New York, N.Y.). 298: 1587-92. PMID 12446902 DOI: 10.1126/Science.1076194  0.54
2002 Wu JW, Krawitz AR, Chai J, Li W, Zhang F, Luo K, Shi Y. Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling. Cell. 111: 357-67. PMID 12419246 DOI: 10.1016/S0092-8674(02)01006-1  0.505
2002 Kipp RA, Case MA, Wist AD, Cresson CM, Carrell M, Griner E, Wiita A, Albiniak PA, Chai J, Shi Y, Semmelhack MF, McLendon GL. Molecular targeting of inhibitor of apoptosis proteins based on small molecule mimics of natural binding partners Biochemistry. 41: 7344-7349. PMID 12044166 DOI: 10.1021/Bi0121454  0.514
2002 Li W, Srinivasula SM, Chai J, Li P, Wu JW, Zhang Z, Alnemri ES, Shi Y. Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi. Nature Structural Biology. 9: 436-41. PMID 11967569 DOI: 10.1038/Nsb795  0.705
2002 Shiozaki EN, Chai J, Shi Y. Oligomerization and activation of caspase-9, induced by Apaf-1 CARD. Proceedings of the National Academy of Sciences of the United States of America. 99: 4197-202. PMID 11904389 DOI: 10.1073/Pnas.072544399  0.8
2001 Wu JW, Hu M, Chai J, Seoane J, Huse M, Li C, Rigotti DJ, Kyin S, Muir TW, Fairman R, Massagué J, Shi Y. Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling. Molecular Cell. 8: 1277-89. PMID 11779503 DOI: 10.1016/S1097-2765(01)00421-X  0.494
2001 Chai J, Wu Q, Shiozaki E, Srinivasula SM, Alnemri ES, Shi Y. Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding. Cell. 107: 399-407. PMID 11701129 DOI: 10.1016/S0092-8674(01)00544-X  0.81
2001 Wu JW, Cocina AE, Chai J, Hay BA, Shi Y. Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides. Molecular Cell. 8: 95-104. PMID 11511363 DOI: 10.1016/S1097-2765(01)00282-9  0.587
2001 Chai J, Shiozaki E, Srinivasula SM, Wu Q, Datta P, Alnemri ES, Shi Y, Dataa P. Structural basis of caspase-7 inhibition by XIAP. Cell. 104: 769-80. PMID 11257230 DOI: 10.1016/S0092-8674(01)00272-0  0.815
2001 Srinivasula SM, Hegde R, Saleh A, Datta P, Shiozaki E, Chai J, Lee RA, Robbins PD, Fernandes-Alnemri T, Shi Y, Alnemri ES. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature. 410: 112-6. PMID 11242052 DOI: 10.1038/35065125  0.806
2001 Srinivasula SM, Hegde R, Saleh A, Datta P, Shiozaki E, Chai J, Lee R, Robbins PD, Fernandes-Alnemri T, Shi Y, Alnemri ES. Erratum: correction: A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis Nature. 411: 1081-1081. DOI: 10.1038/35082622  0.795
2000 Wu G, Chai J, Suber TL, Wu JW, Du C, Wang X, Shi Y. Structural basis of IAP recognition by Smac/DIABLO. Nature. 408: 1008-12. PMID 11140638 DOI: 10.1038/35050012  0.743
2000 Chai J, Du C, Wu JW, Kyin S, Wang X, Shi Y. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature. 406: 855-62. PMID 10972280 DOI: 10.1038/35022514  0.629
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