Nancy E. Holroyd - Publications

Affiliations: 
Wellcome Sanger Institute 

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Doyle SR, Laing R, Bartley D, Morrison A, Holroyd N, Maitland K, Antonopoulos A, Chaudhry U, Flis I, Howell S, McIntyre J, Gilleard JS, Tait A, Mable B, Kaplan R, et al. Genomic landscape of drug response reveals mediators of anthelmintic resistance. Cell Reports. 41: 111522. PMID 36261007 DOI: 10.1016/j.celrep.2022.111522  0.531
2022 Vianney TJ, Berger DJ, Doyle SR, Sankaranarayanan G, Serubanja J, Nakawungu PK, Besigye F, Sanya RE, Holroyd N, Allan F, Webb EL, Elliott AM, Berriman M, Cotton JA. Genome-wide analysis of Schistosoma mansoni reveals limited population structure and possible praziquantel drug selection pressure within Ugandan hot-spot communities. Plos Neglected Tropical Diseases. 16: e0010188. PMID 35981002 DOI: 10.1371/journal.pntd.0010188  0.551
2022 Duque-Correa MA, Goulding D, Rodgers FH, Gillis JA, Cormie C, Rawlinson KA, Bancroft AJ, Bennett HM, Lotkowska ME, Reid AJ, Speak AO, Scott P, Redshaw N, Tolley C, McCarthy C, ... ... Holroyd N, et al. Defining the early stages of intestinal colonisation by whipworms. Nature Communications. 13: 1725. PMID 35365634 DOI: 10.1038/s41467-022-29334-0  0.539
2021 Kincaid-Smith J, Tracey A, de Carvalho Augusto R, Bulla I, Holroyd N, Rognon A, Rey O, Chaparro C, Oleaga A, Mas-Coma S, Allienne JF, Grunau C, Berriman M, Boissier J, Toulza E. Morphological and genomic characterisation of the Schistosoma hybrid infecting humans in Europe reveals admixture between Schistosoma haematobium and Schistosoma bovis. Plos Neglected Tropical Diseases. 15: e0010062. PMID 34941866 DOI: 10.1371/journal.pntd.0010062  0.618
2021 Rawlinson KA, Reid AJ, Lu Z, Driguez P, Wawer A, Coghlan A, Sankaranarayanan G, Buddenborg SK, Soria CD, McCarthy C, Holroyd N, Sanders M, Hoffmann KF, Wilcockson D, Rinaldi G, et al. Daily rhythms in gene expression of the human parasite Schistosoma mansoni. Bmc Biology. 19: 255. PMID 34852797 DOI: 10.1186/s12915-021-01189-9  0.549
2021 Berger DJ, Crellen T, Lamberton PHL, Allan F, Tracey A, Noonan JD, Kabatereine NB, Tukahebwa EM, Adriko M, Holroyd N, Webster JP, Berriman M, Cotton JA. Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration. Nature Communications. 12: 4776. PMID 34362894 DOI: 10.1038/s41467-021-24958-0  0.617
2020 Ancarola ME, Lichtenstein G, Herbig J, Holroyd N, Mariconti M, Brunetti E, Berriman M, Albrecht K, Marcilla A, Rosenzvit MC, Kamenetzky L, Brehm K, Cucher M. Extracellular non-coding RNA signatures of the metacestode stage of Echinococcus multilocularis. Plos Neglected Tropical Diseases. 14: e0008890. PMID 33253209 DOI: 10.1371/journal.pntd.0008890  0.494
2020 Durrant C, Thiele EA, Holroyd N, Doyle SR, Sallé G, Tracey A, Sankaranarayanan G, Lotkowska ME, Bennett HM, Huckvale T, Abdellah Z, Tchindebet O, Wossen M, Logora MSY, Coulibaly CO, et al. Population genomic evidence that human and animal infections in Africa come from the same populations of Dracunculus medinensis. Plos Neglected Tropical Diseases. 14: e0008623. PMID 33253172 DOI: 10.1371/journal.pntd.0008623  0.528
2020 Doyle SR, Tracey A, Laing R, Holroyd N, Bartley D, Bazant W, Beasley H, Beech R, Britton C, Brooks K, Chaudhry U, Maitland K, Martinelli A, Noonan JD, Paulini M, et al. Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm. Communications Biology. 3: 656. PMID 33168940 DOI: 10.1038/s42003-020-01377-3  0.623
2020 Olson PD, Tracey A, Baillie A, James K, Doyle SR, Buddenborg SK, Rodgers FH, Holroyd N, Berriman M. Complete representation of a tapeworm genome reveals chromosomes capped by centromeres, necessitating a dual role in segregation and protection. Bmc Biology. 18: 165. PMID 33167983 DOI: 10.1186/s12915-020-00899-w  0.548
2020 Sankaranarayanan G, Coghlan A, Driguez P, Lotkowska ME, Sanders M, Holroyd N, Tracey A, Berriman M, Rinaldi G. Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite . Wellcome Open Research. 5: 178. PMID 32789192 DOI: 10.12688/wellcomeopenres.16031.2  0.53
2020 Tracey A, Foster JM, Paulini M, Grote A, Mattick J, Tsai YC, Chung M, Cotton JA, Clark TA, Geber A, Holroyd N, Korlach J, Libro S, Lustigman S, Michalski ML, et al. Nearly Complete Genome Sequence of Brugia malayi Strain FR3. Microbiology Resource Announcements. 9. PMID 32527783 DOI: 10.1128/MRA.00154-20  0.535
2020 Wangwiwatsin A, Protasio AV, Wilson S, Owusu C, Holroyd NE, Sanders MJ, Keane J, Doenhoff MJ, Rinaldi G, Berriman M. Transcriptome of the parasitic flatworm Schistosoma mansoni during intra-mammalian development. Plos Neglected Tropical Diseases. 14: e0007743. PMID 32374726 DOI: 10.1371/Journal.Pntd.0007743  0.564
2020 Foster JM, Grote A, Mattick J, Tracey A, Tsai YC, Chung M, Cotton JA, Clark TA, Geber A, Holroyd N, Korlach J, Li Y, Libro S, Lustigman S, Michalski ML, et al. Sex chromosome evolution in parasitic nematodes of humans. Nature Communications. 11: 1964. PMID 32327641 DOI: 10.1038/S41467-020-15654-6  0.521
2019 Doyle SR, Sankaranarayanan G, Allan F, Berger D, Jimenez Castro PD, Collins JB, Crellen T, Duque-Correa MA, Ellis P, Jaleta TG, Laing R, Maitland K, McCarthy C, Moundai T, Softley B, ... ... Holroyd N, et al. Evaluation of DNA Extraction Methods on Individual Helminth Egg and Larval Stages for Whole-Genome Sequencing. Frontiers in Genetics. 10: 826. PMID 31616465 DOI: 10.3389/Fgene.2019.00826  0.597
2019 Doyle SR, Illingworth CJR, Laing R, Bartley DJ, Redman E, Martinelli A, Holroyd N, Morrison AA, Rezansoff A, Tracey A, Devaney E, Berriman M, Sargison N, Cotton JA, Gilleard JS. Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus. Bmc Genomics. 20: 218. PMID 30876405 DOI: 10.1186/S12864-019-5592-6  0.56
2019 Ittiprasert W, Mann VH, Karinshak SE, Coghlan A, Rinaldi G, Sankaranarayanan G, Chaidee A, Tanno T, KumKhaek C, Prangtaworn P, Mentink-Kane MM, Cochran CJ, Driguez P, Holroyd N, Tracey A, et al. Programmed genome editing of the omega-1 ribonuclease of the blood fluke, . Elife. 8. PMID 30644357 DOI: 10.7554/Elife.41337  0.554
2018 Olson PD, Zarowiecki M, James K, Baillie A, Bartl G, Burchell P, Chellappoo A, Jarero F, Tan LY, Holroyd N, Berriman M. Genome-wide transcriptome profiling and spatial expression analyses identify signals and switches of development in tapeworms. Evodevo. 9: 21. PMID 30455861 DOI: 10.1186/S13227-018-0110-5  0.543
2018 Kanzaki N, Tsai IJ, Tanaka R, Hunt VL, Liu D, Tsuyama K, Maeda Y, Namai S, Kumagai R, Tracey A, Holroyd N, Doyle SR, Woodruff GC, Murase K, Kitazume H, et al. Biology and genome of a newly discovered sibling species of Caenorhabditis elegans. Nature Communications. 9: 3216. PMID 30097582 DOI: 10.1038/S41467-018-05712-5  0.527
2018 Roquis D, Taudt A, Geyer KK, Padalino G, Hoffmann KF, Holroyd N, Berriman M, Aliaga B, Chaparro C, Grunau C, Augusto RdC. Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni. Plos Pathogens. 14: 1007066. PMID 29782530 DOI: 10.1371/Journal.Ppat.1007066  0.51
2018 Sallé G, Laing R, Cotton JA, Maitland K, Martinelli A, Holroyd N, Tracey A, Berriman M, Smith WD, Newlands GFJ, Hanks E, Devaney E, Britton C. Transcriptomic profiling of nematode parasites surviving vaccine exposure. International Journal For Parasitology. PMID 29534987 DOI: 10.1016/J.Ijpara.2018.01.004  0.485
2017 Doyle SR, Laing R, Bartley DJ, Britton C, Chaudhry U, Gilleard JS, Holroyd N, Mable BK, Maitland K, Morrison AA, Tait A, Tracey A, Berriman M, Devaney E, Cotton JA, et al. A genome resequencing-based genetic map reveals the recombination landscape of an outbred parasitic nematode in the presence of polyploidy and polyandry. Genome Biology and Evolution. PMID 29267942 DOI: 10.1093/Gbe/Evx269  0.585
2017 Sargison ND, Redman E, Morrison AA, Bartley DJ, Jackson F, Naghra-van Gijzel H, Holroyd N, Berriman M, Cotton JA, Gilleard JS. A method for single pair mating in an obligate parasitic nematode. International Journal For Parasitology. PMID 29111440 DOI: 10.1016/J.Ijpara.2017.08.010  0.548
2017 Lu Z, Sessler F, Holroyd N, Hahnel S, Quack T, Berriman M, Grevelding CG. A gene expression atlas of adult Schistosoma mansoni and their gonads. Scientific Data. 4: 170118. PMID 28829433 DOI: 10.1038/Sdata.2017.118  0.512
2016 Bennuru S, Cotton JA, Ribeiro JM, Grote A, Harsha B, Holroyd N, Mhashilkar A, Molina DM, Randall AZ, Shandling AD, Unnasch TR, Ghedin E, Berriman M, Lustigman S, Nutman TB. Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont. Mbio. 7. PMID 27881553 DOI: 10.1128/Mbio.02028-16  0.542
2016 Cotton JA, Bennuru S, Grote A, Harsha B, Tracey A, Beech R, Doyle SR, Dunn M, Hotopp JC, Holroyd N, Kikuchi T, Lambert O, Mhashilkar A, Mutowo P, Nursimulu N, et al. The genome of Onchocerca volvulus, agent of river blindness. Nature Microbiology. 2: 16216. PMID 27869790 DOI: 10.1038/Nmicrobiol.2016.216  0.555
2016 Suttiprapa S, Rinaldi G, Tsai IJ, Mann VH, Dubrovsky L, Yan HB, Holroyd N, Huckvale T, Durrant C, Protasio AV, Pushkarsky T, Iordanskiy S, Berriman M, Bukrinsky MI, Brindley PJ. HIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni. Plos Pathogens. 12: e1005931. PMID 27764257 DOI: 10.1371/Journal.Ppat.1005931  0.517
2016 Lu Z, Sessler F, Holroyd N, Hahnel S, Quack T, Berriman M, Grevelding CG. Schistosome sex matters: a deep view into gonad-specific and pairing-dependent transcriptomes reveals a complex gender interplay. Scientific Reports. 6: 31150. PMID 27499125 DOI: 10.1038/Srep31150  0.521
2016 Eves-van den Akker S, Laetsch DR, Thorpe P, Lilley CJ, Danchin EG, Da Rocha M, Rancurel C, Holroyd NE, Cotton JA, Szitenberg A, Grenier E, Montarry J, Mimee B, Duceppe MO, Boyes I, et al. The genome of the yellow potato cyst nematode, Globodera rostochiensis, reveals insights into the basis of parasitism and virulence. Genome Biology. 17: 124. PMID 27286965 DOI: 10.1186/S13059-016-0985-1  0.341
2016 Crellen T, Allan F, David S, Durrant C, Huckvale T, Holroyd N, Emery AM, Rollinson D, Aanensen DM, Berriman M, Webster JP, Cotton JA. Whole genome resequencing of the human parasite Schistosoma mansoni reveals population history and effects of selection. Scientific Reports. 6: 20954. PMID 26879532 DOI: 10.1038/Srep20954  0.557
2016 Hunt VL, Tsai IJ, Coghlan A, Reid AJ, Holroyd N, Foth BJ, Tracey A, Cotton JA, Stanley EJ, Beasley H, Bennett HM, Brooks K, Harsha B, Kajitani R, Kulkarni A, et al. The genomic basis of parasitism in the Strongyloides clade of nematodes. Nature Genetics. PMID 26829753 DOI: 10.1038/Ng.3495  0.604
2015 Winter AD, Gillan V, Maitland K, Emes RD, Roberts B, McCormack G, Weir W, Protasio AV, Holroyd N, Berriman M, Britton C, Devaney E. A novel member of the let-7 microRNA family is associated with developmental transitions in filarial nematode parasites. Bmc Genomics. 16: 331. PMID 25896062 DOI: 10.1186/S12864-015-1536-Y  0.523
2014 Bennett HM, Mok HP, Gkrania-Klotsas E, Tsai IJ, Stanley EJ, Antoun NM, Coghlan A, Harsha B, Traini A, Ribeiro DM, Steinbiss S, Lucas SB, Allinson KS, Price SJ, Santarius TS, ... ... Holroyd N, et al. The genome of the sparganosis tapeworm Spirometra erinaceieuropaei isolated from the biopsy of a migrating brain lesion. Genome Biology. 15: 510. PMID 25413302 DOI: 10.1186/S13059-014-0510-3  0.598
2014 Foth BJ, Tsai IJ, Reid AJ, Bancroft AJ, Nichol S, Tracey A, Holroyd N, Cotton JA, Stanley EJ, Zarowiecki M, Liu JZ, Huckvale T, Cooper PJ, Grencis RK, Berriman M. Whipworm genome and dual-species transcriptome analyses provide molecular insights into an intimate host-parasite interaction. Nature Genetics. 46: 693-700. PMID 24929830 DOI: 10.1038/Ng.3010  0.626
2014 Cotton JA, Lilley CJ, Jones LM, Kikuchi T, Reid AJ, Thorpe P, Tsai IJ, Beasley H, Blok V, Cock PJ, Eves-van den Akker S, Holroyd N, Hunt M, Mantelin S, Naghra H, et al. The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode. Genome Biology. 15: R43. PMID 24580726 DOI: 10.1186/Gb-2014-15-3-R43  0.588
2014 Tsai IJ, Hunt M, Holroyd N, Huckvale T, Berriman M, Kikuchi T. Summarizing specific profiles in illumina sequencing from whole-genome amplified DNA Dna Research. 21: 243-254. PMID 24353264 DOI: 10.1093/Dnares/Dst054  0.51
2013 Laing R, Kikuchi T, Martinelli A, Tsai IJ, Beech RN, Redman E, Holroyd N, Bartley DJ, Beasley H, Britton C, Curran D, Devaney E, Gilabert A, Hunt M, Jackson F, et al. The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery. Genome Biology. 14: R88. PMID 23985316 DOI: 10.1186/Gb-2013-14-8-R88  0.628
2013 Tsai IJ, Zarowiecki M, Holroyd N, Garciarrubio A, Sanchez-Flores A, Brooks KL, Tracey A, Bobes RJ, Fragoso G, Sciutto E, Aslett M, Beasley H, Bennett HM, Cai J, Camicia F, et al. The genomes of four tapeworm species reveal adaptations to parasitism. Nature. 496: 57-63. PMID 23485966 DOI: 10.1038/Nature12031  0.625
2012 Protasio AV, Tsai IJ, Babbage A, Nichol S, Hunt M, Aslett MA, De Silva N, Velarde GS, Anderson TJ, Clark RC, Davidson C, Dillon GP, Holroyd NE, LoVerde PT, Lloyd C, et al. A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni. Plos Neglected Tropical Diseases. 6: e1455. PMID 22253936 DOI: 10.1371/Journal.Pntd.0001455  0.629
2011 Choi YJ, Ghedin E, Berriman M, McQuillan J, Holroyd N, Mayhew GF, Christensen BM, Michalski ML. A deep sequencing approach to comparatively analyze the transcriptome of lifecycle stages of the filarial worm, brugia malayi Plos Neglected Tropical Diseases. 5. PMID 22180794 DOI: 10.1371/Journal.Pntd.0001409  0.617
2009 Holden MT, Heather Z, Paillot R, Steward KF, Webb K, Ainslie F, Jourdan T, Bason NC, Holroyd NE, Mungall K, Quail MA, Sanders M, Simmonds M, Willey D, Brooks K, et al. Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens. Plos Pathogens. 5: e1000346. PMID 19325880 DOI: 10.1371/journal.ppat.1000346  0.351
2009 Holden MT, Seth-Smith HM, Crossman LC, Sebaihia M, Bentley SD, Cerdeño-Tárraga AM, Thomson NR, Bason N, Quail MA, Sharp S, Cherevach I, Churcher C, Goodhead I, Hauser H, Holroyd N, et al. The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients. Journal of Bacteriology. 191: 261-77. PMID 18931103 DOI: 10.1128/JB.01230-08  0.301
2007 Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, ... ... Holroyd N, et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 447: 799-816. PMID 17571346 DOI: 10.1038/Nature05874  0.343
2007 Denoeud F, Kapranov P, Ucla C, Frankish A, Castelo R, Drenkow J, Lagarde J, Alioto T, Manzano C, Chrast J, Dike S, Wyss C, Henrichsen CN, Holroyd N, Dickson MC, et al. Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions. Genome Research. 17: 746-59. PMID 17567994 DOI: 10.1101/Gr.5660607  0.324
2007 Bentley SD, Vernikos GS, Snyder LA, Churcher C, Arrowsmith C, Chillingworth T, Cronin A, Davis PH, Holroyd NE, Jagels K, Maddison M, Moule S, Rabbinowitsch E, Sharp S, Unwin L, et al. Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18. Plos Genetics. 3: e23. PMID 17305430 DOI: 10.1371/Journal.Pgen.0030023  0.358
2006 Fenn K, Conlon C, Jones M, Quail MA, Holroyd NE, Parkhill J, Blaxter M. Phylogenetic relationships of the Wolbachia of nematodes and arthropods. Plos Pathogens. 2: e94. PMID 17040125 DOI: 10.1371/journal.ppat.0020094  0.457
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