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Hongzhe Sun, Ph.D - Publications

Affiliations: 
University of Hong Kong, Downingtown, Hong Kong Island, Hong Kong 
Area:
Bioinorganic chemistry, chemical biology, metallomics, medicinal chemistry for emerging infectious diseases, deep learning and AI
Website:
https://www.bioinorg-chem.hku.hk/
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 He X, Han B, Wang R, Guo Y, Kao RYT, Li H, Sun H, Xia W. Dual-action gallium-flavonoid compounds for combating infection. Rsc Chemical Biology. 4: 774-784. PMID 37799578 DOI: 10.1039/d3cb00033h  0.715
2023 Wang C, Xia Y, Wang R, Li J, Chan CL, Kao RY, Toy PH, Ho PL, Li H, Sun H. Metallo-sideromycin as a dual functional complex for combating antimicrobial resistance. Nature Communications. 14: 5311. PMID 37658047 DOI: 10.1038/s41467-023-40828-3  0.712
2022 Wang R, Chan JF, Wang S, Li H, Zhao J, Ip TK, Zuo Z, Yuen KY, Yuan S, Sun H. Orally administered bismuth drug together with -acetyl cysteine as a broad-spectrum anti-coronavirus cocktail therapy. Chemical Science. 13: 2238-2248. PMID 35310492 DOI: 10.1039/d1sc04515f  0.703
2022 Zhang Q, Wang R, Wang M, Liu C, Koohi-Moghadam M, Wang H, Ho PL, Li H, Sun H. Re-sensitization of carrying multidrug resistant bacteria to colistin by silver. Proceedings of the National Academy of Sciences of the United States of America. 119: e2119417119. PMID 35263219 DOI: 10.1073/pnas.2119417119  0.71
2021 Hu X, Li H, Ip TK, Cheung YF, Koohi-Moghadam M, Wang H, Yang X, Tritton DN, Wang Y, Wang Y, Wang R, Ng KM, Naranmandura H, Tse EW, Sun H. Arsenic trioxide targets Hsp60, triggering degradation of p53 and survivin. Chemical Science. 12: 10893-10900. PMID 34476069 DOI: 10.1039/d1sc03119h  0.712
2021 Yuan S, Yin X, Meng X, Chan JF, Ye ZW, Riva L, Pache L, Chan CC, Lai PM, Chan CC, Poon VK, Lee AC, Matsunaga N, Pu Y, Yuen CK, ... ... Sun H, et al. Clofazimine broadly inhibits coronaviruses including SARS-CoV-2. Nature. PMID 33727703 DOI: 10.1038/s41586-021-03431-4  0.686
2020 Sun H, Zhang Q, Wang R, Wang H, Wong YT, Wang M, Hao Q, Yan A, Kao RY, Ho PL, Li H. Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin. Nature Communications. 11: 5263. PMID 33067430 DOI: 10.1038/s41467-020-18939-y  0.701
2020 Yuan S, Wang R, Chan JF, Zhang AJ, Cheng T, Chik KK, Ye ZW, Wang S, Lee AC, Jin L, Li H, Jin DY, Yuen KY, Sun H. Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters. Nature Microbiology. PMID 33028965 DOI: 10.1038/s41564-020-00802-x  0.713
2020 Wang R, Wang S, Chan S, Wang Y, Zhang Y, Zuo Z, Chi-Fung Chan G, Li H, Sun H. Bismuth Porphyrin Antagonizes Cisplatin-Induced Nephrotoxicity via Unexpected Metallothionein-Independent Mechanisms. Iscience. 23: 101054. PMID 32353763 DOI: 10.1016/j.isci.2020.101054  0.688
2019 Wang Y, Han B, Xie Y, Wang H, Wang R, Xia W, Li H, Sun H. Combination of gallium(iii) with acetate for combating antibiotic resistant . Chemical Science. 10: 6099-6106. PMID 31360415 DOI: 10.1039/c9sc01480b  0.694
2019 Wang H, Yan A, Liu Z, Yang X, Xu Z, Wang Y, Wang R, Koohi-Moghadam M, Hu L, Xia W, Tang H, Wang Y, Li H, Sun H. Deciphering molecular mechanism of silver by integrated omic approaches enables enhancing its antimicrobial efficacy in E. coli. Plos Biology. 17: e3000292. PMID 31181061 DOI: 10.1371/journal.pbio.3000292  0.698
2019 Chan S, Wang R, Man K, Nicholls J, Li H, Sun H, Chan GC. A Novel Synthetic Compound, Bismuth Zinc Citrate, Could Potentially Reduce Cisplatin-Induced Toxicity Without Compromising the Anticancer Effect Through Enhanced Expression of Antioxidant Protein. Translational Oncology. 12: 788-799. PMID 30921749 DOI: 10.1016/j.tranon.2019.02.003  0.695
2018 Li H, Wang R, Sun H. Systems Approaches for Unveiling the Mechanism of Action of Bismuth Drugs: New Medicinal Applications beyond Helicobacter Pylori Infection. Accounts of Chemical Research. PMID 30596427 DOI: 10.1021/acs.accounts.8b00439  0.73
2018 Wang R, Lai TP, Gao P, Zhang H, Ho PL, Woo PC, Ma G, Kao RY, Li H, Sun H. Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors. Nature Communications. 9: 439. PMID 29382822 DOI: 10.1038/S41467-018-02828-6  0.722
2018 Yang X, Koohi-Moghadam M, Wang R, Chang YY, Woo PCY, Wang J, Li H, Sun H. Metallochaperone UreG serves as a new target for design of urease inhibitor: A novel strategy for development of antimicrobials. Plos Biology. 16: e2003887. PMID 29320492 DOI: 10.1371/journal.pbio.2003887  0.711
2017 Liao X, Yang F, Wang R, He X, Li H, Kao RYT, Xia W, Sun H. Identification of catabolite control protein A fromas a target of silver ions. Chemical Science. 8: 8061-8066. PMID 29568454 DOI: 10.1039/c7sc02251d  0.723
2017 He X, Liao X, Li H, Xia W, Sun H. Bismuth-Induced Inactivation of Ferric Uptake Regulator from Helicobacter pylori. Inorganic Chemistry. PMID 29200284 DOI: 10.1021/acs.inorgchem.7b02380  0.304
2017 Wang Y, Hu L, Xu F, Quan Q, Lai YT, Xia W, Yang Y, Chang YY, Yang X, Chai Z, Wang J, Chu IK, Li H, Sun H. Integrative approach for the analysis of the proteome-wide response to bismuth drugs in Helicobacter pylori. Chemical Science. 8: 4626-4633. PMID 28626571 DOI: 10.1039/c7sc00766c  0.327
2015 Wang M, Lai TP, Wang L, Zhang H, Yang N, Sadler PJ, Sun H. "Anion clamp" allows flexible protein to impose coordination geometry on metal ions. Chemical Communications (Cambridge, England). 51: 7867-70. PMID 25854324 DOI: 10.1039/C4Cc09642H  0.405
2014 Qin F, Zhao H, Li G, Yang H, Li J, Wang R, Liu Y, Hu J, Sun H, Chen R. Size-tunable fabrication of multifunctional Bi2O3 porous nanospheres for photocatalysis, bacteria inactivation and template-synthesis. Nanoscale. 6: 5402-9. PMID 24710180 DOI: 10.1039/c3nr06870f  0.662
2013 Li G, Qin F, Wang R, Xiao S, Sun H, Chen R. BiOX (X=Cl, Br, I) nanostructures: mannitol-mediated microwave synthesis, visible light photocatalytic performance, and Cr(VI) removal capacity. Journal of Colloid and Interface Science. 409: 43-51. PMID 23993783 DOI: 10.1016/j.jcis.2013.07.068  0.659
2013 Du X, Li H, Wang X, Liu Q, Ni J, Sun H. Kinetics and thermodynamics of metal binding to the N-terminus of a human copper transporter, hCTR1. Chemical Communications (Cambridge, England). 49: 9134-6. PMID 23962988 DOI: 10.1039/c3cc45360j  0.67
2012 Qin F, Li G, Wang R, Wu J, Sun H, Chen R. Template-free fabrication of Bi2O3 and (BiO)2CO3 nanotubes and their application in water treatment. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 16491-7. PMID 23090876 DOI: 10.1002/chem.201201989  0.665
2012 Du X, Wang X, Li H, Sun H. Comparison between copper and cisplatin transport mediated by human copper transporter 1 (hCTR1). Metallomics : Integrated Biometal Science. 4: 679-85. PMID 22552365 DOI: 10.1039/c2mt20021j  0.678
2011 Ge R, Sun X, Wang D, Zhou Q, Sun H. Histidine-rich protein Hpn from Helicobacter pylori forms amyloid-like fibrils in vitro and inhibits the proliferation of gastric epithelial AGS cells. Biochimica Et Biophysica Acta. 1813: 1422-7. PMID 21539864 DOI: 10.1016/j.bbamcr.2011.04.005  0.649
2011 Wang X, Du X, Li H, Chan DS, Sun H. The effect of the extracellular domain of human copper transporter (hCTR1) on cisplatin activation. Angewandte Chemie (International Ed. in English). 50: 2706-11. PMID 21387471 DOI: 10.1002/anie.201006739  0.634
2011 Sun X, Ge R, Chiu JF, Sun H, He QY. Identification of Proteins Related to Nickel Homeostasis in Helicobater pylori by Immobilized Metal Affinity Chromatography and Two-Dimensional Gel Electrophoresis. Metal-Based Drugs. 2008: 289490. PMID 18288244 DOI: 10.1155/2008/289490  0.673
2010 Sun X, Ge R, Zhang D, Sun H, He QY. Iron-containing lipoprotein SiaA in SiaABC, the primary heme transporter of Streptococcus pyogenes. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 1265-73. PMID 20607329 DOI: 10.1007/s00775-010-0684-4  0.678
2009 Sun X, Ge R, Cai Z, Sun H, He QY. Iron depletion decreases proliferation and induces apoptosis in a human colonic adenocarcinoma cell line, Caco2. Journal of Inorganic Biochemistry. 103: 1074-81. PMID 19515424 DOI: 10.1016/J.Jinorgbio.2009.05.004  0.649
2009 Sun X, Baker HM, Ge R, Sun H, He QY, Baker EN. Crystal structure and metal binding properties of the lipoprotein MtsA, responsible for iron transport in Streptococcus pyogenes. Biochemistry. 48: 6184-90. PMID 19463017 DOI: 10.1021/Bi900552C  0.673
2008 Cun S, Li H, Ge R, Lin MC, Sun H. A histidine-rich and cysteine-rich metal-binding domain at the C terminus of heat shock protein A from Helicobacter pylori: implication for nickel homeostasis and bismuth susceptibility. The Journal of Biological Chemistry. 283: 15142-51. PMID 18364351 DOI: 10.1074/Jbc.M800591200  0.699
2008 Sun X, Ge R, Chiu JF, Sun H, He QY. Lipoprotein MtsA of MtsABC in Streptococcus pyogenes primarily binds ferrous ion with bicarbonate as a synergistic anion. Febs Letters. 582: 1351-4. PMID 18364240 DOI: 10.1016/j.febslet.2008.03.020  0.679
2007 Ge R, Sun X, Gu Q, Watt RM, Tanner JA, Wong BC, Xia HH, Huang JD, He QY, Sun H. A proteomic approach for the identification of bismuth-binding proteins in Helicobacter pylori. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 12: 831-42. PMID 17503094 DOI: 10.1007/S00775-007-0237-7  0.679
2007 Ge R, Sun H. Bioinorganic chemistry of bismuth and antimony: target sites of metallodrugs. Accounts of Chemical Research. 40: 267-74. PMID 17330963 DOI: 10.1021/ar600001b  0.692
2006 Ge R, Zhang Y, Sun X, Watt RM, He QY, Huang JD, Wilcox DE, Sun H. Thermodynamic and kinetic aspects of metal binding to the histidine-rich protein, Hpn. Journal of the American Chemical Society. 128: 11330-1. PMID 16939237 DOI: 10.1021/Ja062589T  0.666
2006 Ge R, Watt RM, Sun X, Tanner JA, He QY, Huang JD, Sun H. Expression and characterization of a histidine-rich protein, Hpn: potential for Ni2+ storage in Helicobacter pylori. The Biochemical Journal. 393: 285-93. PMID 16164421 DOI: 10.1042/Bj20051160  0.685
2004 Sun X, Sun H, Ge R, Richter M, Woodworth RC, Mason AB, He QY. The low pKa value of iron-binding ligand Tyr188 and its implication in iron release and anion binding of human transferrin. Febs Letters. 573: 181-5. PMID 15327995 DOI: 10.1016/j.febslet.2004.07.076  0.657
1998 Sun H, Li H, Weir RA, Sadler PJ. The First Specific Ti -Protein Complex: Potential Relevance to Anticancer Activity of Titanocenes. Angewandte Chemie (International Ed. in English). 37: 1577-1579. PMID 29710917 DOI: 10.1002/(Sici)1521-3773(19980619)37:11<1577::Aid-Anie1577>3.0.Co;2-M  0.43
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