Roshan Perera, Ph.D. - Publications

Affiliations: 
University of South Carolina, Columbia, SC 
Area:
Bio-inorganic, bio-physical, and bio-organic chemistry; spectroscopy and mechanisms of action of dioxygen- and peroxide-activating heme iron enzymes and model systems; cytochrome P-450; magnetic circular dichroism spectroscopy

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chand S, Ray S, Yadav P, Samanta S, Pierce BS, Perera R. Abiological Catalysis by Myoglobin Mutant with a Genetically Incorporated Unnatural Amino Acid. The Biochemical Journal. PMID 33821889 DOI: 10.1042/BCJ20210091  0.656
2013 Davydov R, Dawson JH, Perera R, Hoffman BM. The use of deuterated camphor as a substrate in (1)H ENDOR studies of hydroxylation by cryoreduced oxy P450cam provides new evidence of the involvement of compound I. Biochemistry. 52: 667-71. PMID 23215047 DOI: 10.1021/Bi301527C  0.498
2013 Ray S, Chand S, Zhang Y, Nussbaum S, Rajeshwar K, Perera R. Implications of active site orientation in myoglobin for direct electron transfer and electrocatalysis based on monolayer and multilayer covalent immobilization on gold electrodes Electrochimica Acta. 99: 85-93. DOI: 10.1016/J.Electacta.2013.03.080  0.754
2012 Stamos B, Loredo L, Chand S, Phan TV, Zhang Y, Mohapatra S, Rajeshwar K, Perera R. Biosynthetic approach for functional protein microarrays. Analytical Biochemistry. 424: 114-23. PMID 22370272 DOI: 10.1016/J.Ab.2012.02.019  0.736
2011 Du J, Perera R, Dawson JH. Alkylamine-ligated H93G myoglobin cavity mutant: a model system for endogenous lysine and terminal amine ligation in heme proteins such as nitrite reductase and cytochrome f. Inorganic Chemistry. 50: 1242-9. PMID 21250678 DOI: 10.1021/Ic101644U  0.663
2011 Perera R, Sono M, Voegtle HL, Dawson JH. Molecular basis for the inability of an oxygen atom donor ligand to replace the natural sulfur donor heme axial ligand in cytochrome P450 catalysis. Spectroscopic characterization of the Cys436Ser CYP2B4 mutant. Archives of Biochemistry and Biophysics. 507: 119-25. PMID 21147058 DOI: 10.1016/J.Abb.2010.12.010  0.747
2011 Perera R, Sono M, Kinloch R, Zhang H, Tarasev M, Im SC, Waskell L, Dawson JH. Stabilization and spectroscopic characterization of the dioxygen complex of wild-type cytochrome P4502B4 (CYP2B4) and its distal side E301Q, T302A and proximal side F429H mutants at subzero temperatures. Biochimica Et Biophysica Acta. 1814: 69-75. PMID 20637316 DOI: 10.1016/J.Bbapap.2010.07.012  0.772
2009 Grünewald J, Hunt GS, Dong L, Niessen F, Wen BG, Tsao ML, Perera R, Kang M, Laffitte BA, Azarian S, Ruf W, Nasoff M, Lerner RA, Schultz PG, Smider VV. Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America. 106: 4337-42. PMID 19246393 DOI: 10.1073/Pnas.0900507106  0.721
2008 Grünewald J, Tsao ML, Perera R, Dong L, Niessen F, Wen BG, Kubitz DM, Smider VV, Ruf W, Nasoff M, Lerner RA, Schultz PG. Immunochemical termination of self-tolerance. Proceedings of the National Academy of Sciences of the United States of America. 105: 11276-80. PMID 18685087 DOI: 10.1073/Pnas.0804157105  0.732
2008 Graziano JJ, Liu W, Perera R, Geierstanger BH, Lesley SA, Schultz PG. Selecting folded proteins from a library of secondary structural elements. Journal of the American Chemical Society. 130: 176-85. PMID 18067292 DOI: 10.1021/Ja074405W  0.758
2007 Perera R, Jin S, Sono M, Dawson JH. Cytochrome P450-catalyzed hydroxylations and epoxidations Metal Ions in Life Sciences. 3: 319-359. DOI: 10.1002/9780470028155.Ch11  0.602
2006 Schultz KC, Supekova L, Ryu Y, Xie J, Perera R, Schultz PG. A genetically encoded infrared probe. Journal of the American Chemical Society. 128: 13984-5. PMID 17061854 DOI: 10.1021/Ja0636690  0.716
2006 Drake IJ, Zhang Y, Gilles MK, Teris Liu CN, Nachimuthu P, Perera RC, Wakita H, Bell AT. An in situ Al K-edge XAS investigation of the local environment of H+- and Cu+-exchanged USY and ZSM-5 zeolites. The Journal of Physical Chemistry. B. 110: 11665-76. PMID 16800461 DOI: 10.1021/Jp058244Z  0.38
2006 Kim SH, Perera R, Hager LP, Dawson JH, Hoffman BM. Rapid freeze-quench ENDOR study of chloroperoxidase compound I: the site of the radical. Journal of the American Chemical Society. 128: 5598-9. PMID 16637602 DOI: 10.1021/Ja060776L  0.557
2006 Qin J, Perera R, Lovelace LL, Dawson JH, Lebioda L. Structures of thiolate- and carboxylate-ligated ferric H93G myoglobin: models for cytochrome P450 and for oxyanion-bound heme proteins. Biochemistry. 45: 3170-7. PMID 16519512 DOI: 10.1021/Bi052171S  0.573
2005 Kim SH, Yang TC, Perera R, Jin S, Bryson TA, Sono M, Davydov R, Dawson JH, Hoffman BM. Cryoreduction EPR and 13C, 19F ENDOR study of substrate-bound substates and solvent kinetic isotope effects in the catalytic cycle of cytochrome P450cam and its T252A mutant. Dalton Transactions (Cambridge, England : 2003). 3464-9. PMID 16234926 DOI: 10.1039/B506764M  0.65
2005 Perera R, Sono M, Raner GM, Dawson JH. Subzero-temperature stabilization and spectroscopic characterization of homogeneous oxyferrous complexes of the cytochrome P450 BM3 (CYP102) oxygenase domain and holoenzyme. Biochemical and Biophysical Research Communications. 338: 365-71. PMID 16197919 DOI: 10.1016/J.Bbrc.2005.08.078  0.556
2005 Sono M, Perera R, Jin S, Makris TM, Sligar SG, Bryson TA, Dawson JH. The influence of substrate on the spectral properties of oxyferrous wild-type and T252A cytochrome P450-CAM. Archives of Biochemistry and Biophysics. 436: 40-9. PMID 15752707 DOI: 10.1016/J.Abb.2004.12.026  0.671
2005 Davydov R, Perera R, Jin S, Yang TC, Bryson TA, Sono M, Dawson JH, Hoffman BM. Substrate modulation of the properties and reactivity of the oxy-ferrous and hydroperoxo-ferric intermediates of cytochrome P450cam as shown by cryoreduction-EPR/ENDOR spectroscopy. Journal of the American Chemical Society. 127: 1403-13. PMID 15686372 DOI: 10.1021/Ja045351I  0.637
2004 Ogura H, Nishida CR, Hoch UR, Perera R, Dawson JH, Ortiz de Montellano PR. EpoK, a cytochrome P450 involved in biosynthesis of the anticancer agents epothilones A and B. Substrate-mediated rescue of a P450 enzyme. Biochemistry. 43: 14712-21. PMID 15544342 DOI: 10.1021/Bi048980D  0.558
2004 Perera R, Dawson JH. Modeling heme protein active sites with the his93gly cavity mutant of sperm whale myoglobin: Complexes with nitrogen-, oxygen- and sulfur-donor proximal ligands Journal of Porphyrins and Phthalocyanines. 8: 246-254. DOI: 10.1142/S1088424604000234  0.59
2003 Perera R, Sono M, Sigman JA, Pfister TD, Lu Y, Dawson JH. Neutral thiol as a proximal ligand to ferrous heme iron: implications for heme proteins that lose cysteine thiolate ligation on reduction. Proceedings of the National Academy of Sciences of the United States of America. 100: 3641-6. PMID 12655049 DOI: 10.1073/Pnas.0737142100  0.617
2003 Voegtle HL, Sono M, Adak S, Pond AE, Tomita T, Perera R, Goodin DB, Ikeda-Saito M, Stuehr DJ, Dawson JH. Spectroscopic characterization of five- and six-coordinate ferrous-NO heme complexes. Evidence for heme Fe-proximal cysteinate bond cleavage in the ferrous-NO adducts of the Trp-409Tyr/Phe proximal environment mutants of neuronal nitric oxide synthase. Biochemistry. 42: 2475-84. PMID 12600215 DOI: 10.1021/Bi0271502  0.748
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