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David Threadgill - Publications

Affiliations: 
1996-2000 Cell Biology Vanderbilt University, Nashville, TN 
 2000-2008 Genetics University of North Carolina, Chapel Hill, Chapel Hill, NC 
 2008-2013 Genetics North Carolina State University, Raleigh, NC 
 2013- Molecular and Cellular Medicine Texas A & M University, College Station, TX, United States 
Area:
Genetics
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114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Huda MN, Salvador AC, Barrington WT, Gacasan CA, D'Souza EM, Deus Ramirez L, Threadgill DW, Bennett BJ. Gut microbiota and host genetics modulate the effect of diverse diet patterns on metabolic health. Frontiers in Nutrition. 9: 896348. PMID 36061898 DOI: 10.3389/fnut.2022.896348  0.699
2022 Wells AE, Barrington WT, Dearth S, Milind N, Carter GW, Threadgill DW, Campagna SR, Voy BH. Independent and Interactive Effects of Genetic Background and Sex on Tissue Metabolomes of Adipose, Skeletal Muscle, and Liver in Mice. Metabolites. 12. PMID 35448524 DOI: 10.3390/metabo12040337  0.715
2021 Mantilla Rojas C, McGill MP, Salvador AC, Bautz D, Threadgill DW. Epithelial-specific ERBB3 deletion results in a genetic background-dependent increase in intestinal and colon polyps that is mediated by EGFR. Plos Genetics. 17: e1009931. PMID 34843459 DOI: 10.1371/journal.pgen.1009931  0.339
2021 Mantilla-Rojas C, Yu M, Rinella ES, Lynch RM, Perry A, Jaimes-Alvarado J, Anderson KR, Barba E, Bourgeois EJ, Konganti K, Threadgill DW. A molecular subtype of colorectal cancers initiates independently of epidermal growth factor receptor and has an accelerated growth rate mediated by IL10-dependent anergy. Oncogene. PMID 33767440 DOI: 10.1038/s41388-021-01752-2  0.802
2021 Salvador AC, Arends D, Barrington WT, Elsaadi AM, Brockmann GA, Threadgill DW. Sex-specific genetic architecture in response to American and ketogenic diets. International Journal of Obesity (2005). PMID 33723359 DOI: 10.1038/s41366-021-00785-7  0.713
2020 Sigmon JS, Blanchard MW, Baric RS, Bell TA, Brennan J, Brockmann GA, Burks AW, Calabrese JM, Caron KM, Cheney RE, Ciavatta D, Conlon F, Darr DB, Faber J, Franklin C, ... ... Threadgill DW, et al. Content and Performance of the MiniMUGA Genotyping Array, a New Tool To Improve Rigor and Reproducibility in Mouse Research. Genetics. PMID 33067325 DOI: 10.1534/genetics.120.303596  0.735
2020 Garbutt TA, Konganti K, Konneker T, Hillhouse A, Phelps D, Jones A, Aylor D, Threadgill DW. Derivation of stable embryonic stem cell-like, but transcriptionally heterogenous, induced pluripotent stem cells from non-permissive mouse strains. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 33015751 DOI: 10.1007/s00335-020-09849-x  0.783
2020 Arora S, Li X, Hillhouse A, Konganti K, Little SV, Lawhon SD, Threadgill D, Shelburne S, Hook M. Staphylococcus epidermidis MSCRAMM SesJ Is Encoded in Composite Islands. Mbio. 11. PMID 32071265 DOI: 10.1128/Mbio.02911-19  0.304
2019 Bissahoyo AC, Xie Y, Yang L, Pearsall RS, Lee D, Elliott RW, Demant P, McMillan L, Pardo-Manuel de Villena F, Angel JM, Threadgill DW. A New Polygenic Model for Non-familial Colorectal Cancer Inheritance Based on the Genetic Architecture of the Azoxymethane-Induced Mouse Model. Genetics. PMID 31879319 DOI: 10.1534/Genetics.119.302833  0.793
2018 Cuomo D, Porreca I, Ceccarelli M, Threadgill DW, Barrington WT, Petriella A, D'Angelo F, Cobellis G, De Stefano F, D'Agostino MN, De Felice M, Mallardo M, Ambrosino C. Transcriptional landscape of mouse-aged ovaries reveals a unique set of non-coding RNAs associated with physiological and environmental ovarian dysfunctions. Cell Death Discovery. 4: 112. PMID 30534420 DOI: 10.1038/S41420-018-0121-Y  0.697
2018 Garbutt TA, Konneker TI, Konganti K, Hillhouse AE, Swift-Haire F, Jones A, Phelps D, Aylor DL, Threadgill DW. Permissiveness to form pluripotent stem cells may be an evolutionarily derived characteristic in Mus musculus. Scientific Reports. 8: 14706. PMID 30279419 DOI: 10.1038/S41598-018-32116-8  0.776
2018 Wells A, Barrington WT, Dearth S, May A, Threadgill DW, Campagna SR, Voy BH. Tissue Level Diet and Sex-by-Diet Interactions Reveal Unique Metabolite and Clustering Profiles Using Untargeted Liquid Chromatography-Mass Spectrometry on Adipose, Skeletal Muscle, and Liver Tissue in C57BL6/J Mice. Journal of Proteome Research. PMID 29373032 DOI: 10.1021/Acs.Jproteome.7B00750  0.682
2017 Barrington WT, Wulfridge P, Wells AE, Rojas CM, Howe SYF, Perry A, Hua K, Pellizzon MA, Hansen KD, Voy BH, Bennett BJ, Pomp D, Feinberg AP, Threadgill DW. Improving Metabolic Health Through Precision Dietetics in Mice. Genetics. PMID 29158425 DOI: 10.1534/Genetics.117.300536  0.707
2017 Rojas CM, Threadgill D. Abstract A15: Progression of colorectal cancer through epidermal growth factor receptor (EGFR)-independent mechanisms Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-A15  0.322
2017 Rojas CM, Ming Y, Threadgill D. Abstract 3400: Progression of epidermal growth factor receptor (EGFR)-independent colorectal cancer Cancer Research. 77: 3400-3400. DOI: 10.1158/1538-7445.Am2017-3400  0.339
2017 Lanier A, Barrington W, Threadgill D. Abstract 1542: Identifying genetic modifiers ofPTENusing the Collaborative Cross mouse panel Cancer Research. 77: 1542-1542. DOI: 10.1158/1538-7445.Am2017-1542  0.721
2017 Leitschuh CM, Kanavy D, Backus GA, Valdez RX, Serr M, Pitts EA, Threadgill D, Godwin J. Developing gene drive technologies to eradicate invasive rodents from islands Journal of Responsible Innovation. 5: S121-S138. DOI: 10.1080/23299460.2017.1365232  0.769
2016 Mantilla-Rojas C, Yu M, Threadgill D. Abstract LB-039: Genetic dissection of mechanisms underlying epidermal growth factor receptor-independent colorectal cancer development Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-039  0.552
2015 Crowley JJ, Zhabotynsky V, Sun W, Huang S, Pakatci IK, Kim Y, Wang JR, Morgan AP, Calaway JD, Aylor DL, Yun Z, Bell TA, Buus RJ, Calaway ME, Didion JP, ... ... Threadgill DW, et al. Corrigendum: Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance. Nature Genetics. 47: 690. PMID 26018903 DOI: 10.1038/Ng0615-690A  0.767
2015 Crowley JJ, Zhabotynsky V, Sun W, Huang S, Pakatci IK, Kim Y, Wang JR, Morgan AP, Calaway JD, Aylor DL, Yun Z, Bell TA, Buus RJ, Calaway ME, Didion JP, ... ... Threadgill DW, et al. Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance. Nature Genetics. 47: 353-60. PMID 25730764 DOI: 10.1038/Ng.3222  0.8
2015 Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, ... ... Threadgill DW, et al. A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2. Plos Genetics. 11: e1004850. PMID 25679959 DOI: 10.1371/Journal.Pgen.1004850  0.714
2015 Church RJ, Gatti DM, Urban TJ, Long N, Yang X, Shi Q, Eaddy JS, Mosedale M, Ballard S, Churchill GA, Navarro V, Watkins PB, Threadgill DW, Harrill AH. Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 76: 19-26. PMID 25446466 DOI: 10.1016/J.Fct.2014.11.008  0.686
2015 Donohoe D, Holley D, Collins L, Montgomery S, Whitmore A, Curry K, Renner S, Greenwalt A, Ryan E, Godfrey V, Threadgill D, Swenberg J, Threadgill D, Bultman S. Abstract PL03-01: A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-Pl03-01  0.343
2014 Phillippi J, Xie Y, Miller DR, Bell TA, Zhang Z, Lenarcic AB, Aylor DL, Krovi SH, Threadgill DW, Pardo-Manuel De Villena F, Wang W, Valdar W, Frelinger JA. Using the emerging Collaborative Cross to probe the immune system Genes and Immunity. 15: 38-46. PMID 24195963 DOI: 10.1038/Gene.2013.59  0.672
2014 Donohoe D, Holley D, Collins L, Montgomery S, Whitmore A, Hillhouse A, Curry K, Renner S, Greenwalt A, Ryan E, Godfrey V, Heise M, Threadgill D, Swenberg J, Threadgill D, et al. Abstract SY04-02: Dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy04-02  0.336
2013 Desimone MC, Rathmell WK, Threadgill DW. Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response. Journal of the National Cancer Institute. 105: 1355-64. PMID 23990666 DOI: 10.1093/Jnci/Djt226  0.781
2013 Saito K, Horiuchi K, Kimura T, Mizuno S, Yoda M, Morioka H, Akiyama H, Threadgill D, Okada Y, Toyama Y, Sato K. Conditional inactivation of TNFα-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones. Plos One. 8: e54853. PMID 23349978 DOI: 10.1371/Journal.Pone.0054853  0.373
2013 Threadgill D. Abstract CN02-02: Elucidating mechanisms of environmentally induced kidney cancers Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-Cn02-02  0.394
2013 Song X, Fan P, Guha U, Threadgill D, Varmus H, Politi K. Abstract C113: ERBB3 independent activation of the PI3K pathway in EGFR mutant lung adenocarcinomas. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C113  0.368
2012 Eversley CD, Yuying X, Pearsall RS, Threadgill DW. Mapping six new susceptibility to colon cancer (Scc) loci using a mouse interspecific backcross. G3 (Bethesda, Md.). 2: 1577-84. PMID 23275880 DOI: 10.1534/G3.112.002253  0.807
2012 Mustafi R, Dougherty U, Shah H, Dehghan H, Gliksberg A, Wu J, Zhu H, Joseph L, Hart J, Dive C, Fichera A, Threadgill D, Bissonnette M. Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts. Carcinogenesis. 33: 1930-9. PMID 22791816 DOI: 10.1093/Carcin/Bgs231  0.407
2012 Rinella ES, Threadgill DW. Efficacy of EGFR inhibition is modulated by model, sex, genetic background and diet: implications for preclinical cancer prevention and therapy trials. Plos One. 7: e39552. PMID 22761823 DOI: 10.1371/Journal.Pone.0039552  0.807
2012 Iraqi FA, Mahajne M, Salaymah Y, Sandovski H, Tayem H, Vered K, Balmer L, Hall M, Manship G, Morahan G, Pettit K, Scholten J, Tweedie K, Wallace A, Weerasekera L, ... ... Threadgill DW, et al. The genome architecture of the collaborative cross mouse genetic reference population Genetics. 190: 389-401. PMID 22345608 DOI: 10.1534/Genetics.111.132639  0.748
2012 Rinella ES, Bankaitis ED, Threadgill DW. Dietary calcium supplementation enhances efficacy but also toxicity of EGFR inhibitor therapy for colon cancer. Cancer Biology & Therapy. 13: 130-7. PMID 22231407 DOI: 10.4161/Cbt.13.3.18690  0.784
2012 Chen J, Chen JK, Nagai K, Plieth D, Tan M, Lee TC, Threadgill DW, Neilson EG, Harris RC. EGFR signaling promotes TGFβ-dependent renal fibrosis. Journal of the American Society of Nephrology : Jasn. 23: 215-24. PMID 22095949 DOI: 10.1681/ASN.2011070645  0.781
2011 Zhang X, Tamasi J, Lu X, Zhu J, Chen H, Tian X, Lee TC, Threadgill DW, Kream BE, Kang Y, Partridge NC, Qin L. Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1022-34. PMID 21542005 DOI: 10.1002/Jbmr.295  0.792
2011 Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, ... ... Threadgill D, et al. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Research. 21: 1213-22. PMID 21406540 DOI: 10.1101/Gr.111310.110  0.713
2011 Bradford BU, Lock EF, Kosyk O, Kim S, Uehara T, Harbourt D, DeSimone M, Threadgill DW, Tryndyak V, Pogribny IP, Bleyle L, Koop DR, Rusyn I. Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: 206-17. PMID 21135412 DOI: 10.1093/Toxsci/Kfq362  0.795
2010 Eversley CD, Clark T, Xie Y, Steigerwalt J, Bell TA, de Villena FP, Threadgill DW. Genetic mapping and developmental timing of transmission ratio distortion in a mouse interspecific backcross. Bmc Genetics. 11: 98. PMID 21044349 DOI: 10.1186/1471-2156-11-98  0.787
2010 La Merrill M, Harper R, Birnbaum LS, Cardiff RD, Threadgill DW. Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice. Environmental Health Perspectives. 118: 596-601. PMID 20435547 DOI: 10.1289/Ehp.0901047  0.63
2010 Gordon RR, La Merrill M, Hunter KW, Sørensen P, Threadgill DW, Pomp D. Dietary fat-dependent transcriptional architecture and copy number alterations associated with modifiers of mammary cancer metastasis. Clinical & Experimental Metastasis. 27: 279-93. PMID 20354763 DOI: 10.1007/S10585-010-9326-Z  0.659
2010 La Merrill M, Gordon RR, Hunter KW, Threadgill DW, Pomp D. Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression. Clinical & Experimental Metastasis. 27: 107-16. PMID 20151316 DOI: 10.1007/S10585-009-9302-7  0.659
2010 Zhang Z, Pascuet E, Hueber PA, Chu L, Bichet DG, Lee TC, Threadgill DW, Goodyer P. Targeted inactivation of EGF receptor inhibits renal collecting duct development and function. Journal of the American Society of Nephrology : Jasn. 21: 573-8. PMID 20133479 DOI: 10.1681/Asn.2009070719  0.795
2010 Mascia F, Cataisson C, Lee TC, Threadgill D, Mariani V, Amerio P, Chandrasekhara C, Souto Adeva G, Girolomoni G, Yuspa SH, Pastore S. EGFR regulates the expression of keratinocyte-derived granulocyte/macrophage colony-stimulating factor in vitro and in vivo. The Journal of Investigative Dermatology. 130: 682-93. PMID 19890352 DOI: 10.1038/Jid.2009.336  0.785
2010 Song Y, Zhang Q, Miller CR, Threadgill D, McCarthy KD, Dyke TV. Abstract LB-150: Role of EGFR signaling in an inducible mouse model of astrocytomas Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-150  0.393
2010 Mascia F, Lam G, Threadgill D, Yuspa SH. Abstract 18: Targeted epidermal ablation of EGFR causes local and systemic inflammation Cancer Research. 70: 18-18. DOI: 10.1158/1538-7445.Am10-18  0.366
2010 Reiter JL, Threadgill DW, Eley GD, Strunk KE, Danielsen AJ, Sinclair CS, Pearsall RS, Green PJ, Yee D, Lampland AL, Balasubramaniam S, Crossley TD, Magnuson TR, James CD, Maihle NJ. Corrigendum to “Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms” [Genomics 71 (2001) 1–20] Genomics. 96: 128. DOI: 10.1016/J.Ygeno.2010.05.004  0.508
2009 Dougherty U, Cerasi D, Taylor I, Kocherginsky M, Tekin U, Badal S, Aluri L, Sehdev A, Cerda S, Mustafi R, Delgado J, Joseph L, Zhu H, Hart J, Threadgill D, et al. Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: roles of transforming growth factor-{alpha} and PTGS2. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6780-9. PMID 19903783 DOI: 10.1158/1078-0432.Ccr-09-1678  0.353
2009 La Merrill M, Kuruvilla BS, Pomp D, Birnbaum LS, Threadgill DW. Dietary fat alters body composition, mammary development, and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors. Environmental Health Perspectives. 117: 1414-9. PMID 19750107 DOI: 10.1289/Ehp.0800530  0.638
2009 Lee D, Yu M, Lee E, Kim H, Yang Y, Kim K, Pannicia C, Kurie JM, Threadgill DW. Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium. The Journal of Clinical Investigation. 119: 2702-13. PMID 19690388 DOI: 10.1172/Jci36435  0.468
2009 Gatti DM, Harrill AH, Wright FA, Threadgill DW, Rusyn I. Replication and narrowing of gene expression quantitative trait loci using inbred mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 437-46. PMID 19609828 DOI: 10.1007/S00335-009-9199-0  0.709
2009 Dackor J, Caron KM, Threadgill DW. Placental and embryonic growth restriction in mice with reduced function epidermal growth factor receptor alleles. Genetics. 183: 207-18. PMID 19564486 DOI: 10.1534/Genetics.109.104372  0.805
2009 Barrick CJ, Dong A, Waikel R, Corn D, Yang F, Threadgill DW, Smyth SS. Parent-of-origin effects on cardiac response to pressure overload in mice. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1003-9. PMID 19561308 DOI: 10.1152/Ajpheart.00896.2008  0.79
2009 Dackor J, Li M, Threadgill DW. Placental overgrowth and fertility defects in mice with a hypermorphic allele of epidermal growth factor receptor. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 339-49. PMID 19466482 DOI: 10.1007/S00335-009-9189-2  0.815
2009 Barrick CJ, Roberts RB, Rojas M, Rajamannan NM, Suitt CB, O'Brien KD, Smyth SS, Threadgill DW. Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice. American Journal of Physiology. Heart and Circulatory Physiology. 297: H65-75. PMID 19448146 DOI: 10.1152/Ajpheart.00866.2008  0.796
2009 Uronis JM, Threadgill DW. Murine models of colorectal cancer. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 261-8. PMID 19444507 DOI: 10.1007/S00335-009-9186-5  0.683
2009 Harrill AH, Ross PK, Gatti DM, Threadgill DW, Rusyn I. Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel. Toxicological Sciences : An Official Journal of the Society of Toxicology. 110: 235-43. PMID 19420014 DOI: 10.1093/Toxsci/Kfp096  0.717
2009 Harrill AH, Watkins PB, Su S, Ross PK, Harbourt DE, Stylianou IM, Boorman GA, Russo MW, Sackler RS, Harris SC, Smith PC, Tennant R, Bogue M, Paigen K, Harris C, ... ... Threadgill DW, et al. Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans. Genome Research. 19: 1507-15. PMID 19416960 DOI: 10.1101/Gr.090241.108  0.69
2009 Pysz MA, Leontieva OV, Bateman NW, Uronis JM, Curry KJ, Threadgill DW, Janssen KP, Robine S, Velcich A, Augenlicht LH, Black AR, Black JD. PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. Experimental Cell Research. 315: 1415-28. PMID 19232344 DOI: 10.1016/J.Yexcr.2009.02.002  0.698
2009 Lee TC, Threadgill DW. Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor. Genesis (New York, N.Y. : 2000). 47: 85-92. PMID 19115345 DOI: 10.1002/Dvg.20464  0.809
2009 La Merrill M, Baston DS, Denison MS, Birnbaum LS, Pomp D, Threadgill DW. Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat. American Journal of Physiology. Endocrinology and Metabolism. 296: E203-10. PMID 18840765 DOI: 10.1152/Ajpendo.90368.2008  0.636
2009 Maklad A, Nicolai JR, Bichsel KJ, Evenson JE, Lee TC, Threadgill DW, Hansen LA. The EGFR is required for proper innervation to the skin. The Journal of Investigative Dermatology. 129: 690-8. PMID 18830272 DOI: 10.1038/Jid.2008.281  0.795
2008 Abate-Shen C, Brown PH, Colburn NH, Gerner EW, Green JE, Lipkin M, Nelson WG, Threadgill D. The untapped potential of genetically engineered mouse models in chemoprevention research: opportunities and challenges. Cancer Prevention Research (Philadelphia, Pa.). 1: 161-6. PMID 19138951 DOI: 10.1158/1940-6207.Capr-08-0076  0.322
2008 Radiloff DR, Rinella ES, Threadgill DW. Modeling cancer patient populations in mice: complex genetic and environmental factors. Drug Discovery Today. Disease Models. 4: 83-88. PMID 19122874 DOI: 10.1016/J.Ddmod.2007.06.004  0.795
2008 Barrick CJ, Yu M, Chao HH, Threadgill DW. Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice. Toxicology and Applied Pharmacology. 228: 315-25. PMID 18313710 DOI: 10.1016/J.Taap.2007.12.012  0.801
2008 Gordon RR, Hunter KW, La Merrill M, Sørensen P, Threadgill DW, Pomp D. Genotype X diet interactions in mice predisposed to mammary cancer: II. Tumors and metastasis. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 19: 179-89. PMID 18288525 DOI: 10.1007/S00335-008-9096-Y  0.652
2007 Uronis JM, Herfarth HH, Rubinas TC, Bissahoyo AC, Hanlon K, Threadgill DW. Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage. Cancer Research. 67: 11594-600. PMID 18089788 DOI: 10.1158/0008-5472.Can-07-3242  0.785
2007 Dackor J, Strunk KE, Wehmeyer MM, Threadgill DW. Altered Trophoblast Proliferation is Insufficient to Account for Placental Dysfunction in Egfr Null Embryos Placenta. 28: 1211-1218. PMID 17822758 DOI: 10.1016/J.Placenta.2007.07.005  0.817
2007 Chi YY, Ibrahim JG, Bissahoyo A, Threadgill DW. Bayesian hierarchical modeling for time course microarray experiments. Biometrics. 63: 496-504. PMID 17688501 DOI: 10.1111/J.1541-0420.2006.00689.X  0.774
2007 Kaiser S, Park YK, Franklin JL, Halberg RB, Yu M, Jessen WJ, Freudenberg J, Chen X, Haigis K, Jegga AG, Kong S, Sakthivel B, Xu H, Reichling T, Azhar M, ... ... Threadgill DW, et al. Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biology. 8: R131. PMID 17615082 DOI: 10.1186/Gb-2007-8-7-R131  0.785
2007 Huang H, Eversley CD, Threadgill DW, Zou F. Bayesian multiple quantitative trait loci mapping for complex traits using markers of the entire genome. Genetics. 176: 2529-40. PMID 17483433 DOI: 10.1534/Genetics.106.064980  0.773
2007 Barrick CJ, Rojas M, Schoonhoven R, Smyth SS, Threadgill DW. Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2119-30. PMID 17172276 DOI: 10.1152/Ajpheart.00816.2006  0.793
2007 Moy SS, Nadler JJ, Young NB, Perez A, Holloway LP, Barbaro RP, Barbaro JR, Wilson LM, Threadgill DW, Lauder JM, Magnuson TR, Crawley JN. Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains. Behavioural Brain Research. 176: 4-20. PMID 16971002 DOI: 10.1016/J.Bbr.2006.07.030  0.511
2006 Roberts RB, Thompson CL, Lee D, Mankinen RW, Sancar A, Threadgill DW. Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice. Journal of Circadian Rhythms. 4: 15. PMID 17109754 DOI: 10.1186/1740-3391-4-15  0.73
2006 Deloris Alexander A, Orcutt RP, Henry JC, Baker J, Bissahoyo AC, Threadgill DW. Quantitative PCR assays for mouse enteric flora reveal strain-dependent differences in composition that are influenced by the microenvironment. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 1093-104. PMID 17091319 DOI: 10.1007/S00335-006-0063-1  0.789
2006 Nadler JJ, Zou F, Huang H, Moy SS, Lauder J, Crawley JN, Threadgill DW, Wright FA, Magnuson TR. Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype. Genetics. 174: 1229-36. PMID 16980393 DOI: 10.1534/Genetics.106.061481  0.538
2006 Rinella ES, Eversley CD, Carroll IM, Andrus JM, Threadgill DW, Threadgill DS. Human epithelial-specific response to pathogenic Campylobacter jejuni. Fems Microbiology Letters. 262: 236-43. PMID 16923081 DOI: 10.1111/J.1574-6968.2006.00396.X  0.762
2006 Roberts RB, Thompson CL, Lee D, Mankinen RW, Sancar A, Threadgill DW. Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice Journal of Circadian Rhythms. 4. DOI: 10.1186/1740-3391-4-15  0.697
2005 Mrosovsky N, Redlin U, Roberts RB, Threadgill DW. Masking in waved-2 mice: EGF receptor control of locomotion questioned. Chronobiology International. 22: 963-74. PMID 16393701 DOI: 10.1080/07420520500395086  0.692
2005 Fujimoto N, Wislez M, Zhang J, Iwanaga K, Dackor J, Hanna AE, Kalyankrishna S, Cody DD, Price RE, Sato M, Shay JW, Minna JD, Peyton M, Tang X, Massarelli E, ... ... Threadgill DW, et al. High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor. Cancer Research. 65: 11478-85. PMID 16357156 DOI: 10.1158/0008-5472.Can-05-1977  0.792
2005 Bissahoyo A, Pearsall RS, Hanlon K, Amann V, Hicks D, Godfrey VL, Threadgill DW. Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: effects of dose, route, and diet. Toxicological Sciences : An Official Journal of the Society of Toxicology. 88: 340-5. PMID 16150884 DOI: 10.1093/Toxsci/Kfi313  0.805
2004 Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, ... ... Threadgill D, et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics. 36: 1133-7. PMID 15514660 DOI: 10.1038/Ng1104-1133  0.33
2004 Hahn H, Nitzki F, Schorban T, Hemmerlein B, Threadgill D, Rosemann M. Genetic mapping of a Ptch1-associated rhabdomyosarcoma susceptibility locus on mouse chromosome 2. Genomics. 84: 853-8. PMID 15475264 DOI: 10.1016/J.Ygeno.2004.07.002  0.406
2004 Lee D, Cross SH, Strunk KE, Morgan JE, Bailey CL, Jackson IJ, Threadgill DW. Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 525-36. PMID 15366372  0.8
2004 Strunk KE, Amann V, Threadgill DW. Phenotypic variation resulting from a deficiency of epidermal growth factor receptor in mice is caused by extensive genetic heterogeneity that can be genetically and molecularly partitioned. Genetics. 167: 1821-32. PMID 15342520 DOI: 10.1534/genetics.103.020495  0.812
2004 Roberts RB, Arteaga CL, Threadgill DW. Modeling the cancer patient with genetically engineered mice: prediction of toxicity from molecule-targeted therapies. Cancer Cell. 5: 115-20. PMID 14998487 DOI: 10.1016/S1535-6108(04)00032-7  0.682
2003 Wood BC, Roberts RB, Lee D, Threadgill DW. Molecular and genetic analysis of a carcinogen-based mouse model for hepatocarcinogenesis Gastroenterology. 124: A742. DOI: 10.1016/S0016-5085(03)83748-4  0.688
2002 Roberts RB, Min L, Washington MK, Olsen SJ, Settle SH, Coffey RJ, Threadgill DW. Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 1521-6. PMID 11818567 DOI: 10.1073/Pnas.032678499  0.732
2001 Reiter JL, Threadgill DW, Eley GD, Strunk KE, Danielsen AJ, Sinclair CS, Pearsall RS, Green PJ, Yee D, Lampland AL, Balasubramaniam S, Crossley TD, Magnuson TR, James CD, Maihle NJ. Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms. Genomics. 71: 1-20. PMID 11161793 DOI: 10.1006/Geno.2000.6341  0.568
2001 Coffey RJ, Roberts R, Settle SH, Whitehead R, Washington K, Threadgill D. Genetic support for a critical role EGF receptor signaling in intestinal neoplasia in ApcMin mice Gastroenterology. 120: A18. DOI: 10.1016/S0016-5085(08)80086-8  0.72
2000 Denning MF, Dlugosz AA, Cheng C, Dempsey PJ, Coffey RJ, Threadgill DW, Magnuson T, Yuspa SH. Cross-talk between epidermal growth factor receptor and protein kinase C during calcium-induced differentiation of keratinocytes Experimental Dermatology. 9: 192-199. PMID 10839717 DOI: 10.1034/J.1600-0625.2000.009003192.X  0.516
1999 Nishimura H, Yerkes E, Hohenfellner K, Miyazaki Y, Ma J, Hunley TE, Yoshida H, Ichiki T, Threadgill D, Phillips JA, Hogan BM, Fogo A, Brock JW, Inagami T, Ichikawa I. Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men. Molecular Cell. 3: 1-10. PMID 10024874 DOI: 10.1016/S1097-2765(00)80169-0  0.354
1997 Threadgill DW, Yee D, Matin A, Nadeau JH, Magnuson T. Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain Mammalian Genome. 8: 390-393. PMID 9166580 DOI: 10.1007/S003359900453  0.557
1996 Tong BJ, Das SK, Threadgill D, Magnuson T, Dey SK. Differential expression of the full-length and truncated forms of the epidermal growth factor receptor in the preimplantation mouse uterus and blastocyst Endocrinology. 137: 1492-1496. PMID 8625928 DOI: 10.1210/Endo.137.4.8625928  0.35
1996 Denning MF, Dlugosz AA, Threadgill DW, Magnuson T, Yuspa SH. Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C δ Journal of Biological Chemistry. 271: 5325-5331. PMID 8621384 DOI: 10.1074/Jbc.271.10.5325  0.527
1994 Threadgill DS, Threadgill DW, Moll YD, Weiss JA, Zhang N, Davey HW, Wildeman AG, Womack JE. Syntenic Assignment of Human Chromosome 1 Homologous Loci in the Bovine Genomics. 22: 626-630. PMID 8001974 DOI: 10.1006/geno.1994.1436  0.437
1993 Gallagher DS, Threadgill DW, Ryan AM, Womack JE, Irwin DM. Physical mapping of the lysozyme gene family in cattle Mammalian Genome. 4: 368-373. PMID 8102916 DOI: 10.1007/BF00360587  0.435
1992 Sharan SK, Holdener-Kenny B, Threadgill DW, Magnuson T. Genomic mapping within the albino-deletion complex using individual early postimplantation mouse embryos Mammalian Genome. 3: 79-83. PMID 1617218 DOI: 10.1007/Bf00431250  0.528
1992 Zhang N, Threadgill DW, Womack JE. Synteny mapping in the bovine: Genes from human chromosome 4 Genomics. 14: 131-136. PMID 1427820 DOI: 10.1016/S0888-7543(05)80295-2  0.47
1992 Dietz AB, Georges M, Threadgill DW, Womack JE, Schuler LA. Somatic cell mapping, polymorphism, and linkage analysis of bovine prolactin-related proteins and placental lactogen Genomics. 14: 137-143. PMID 1358791 DOI: 10.1016/S0888-7543(05)80296-4  0.467
1991 Gallagher DS, Threadgill DW, Jackson AP, Parham P, Womack JE. Somatic cell mapping of bovine clathrin light chain genes: Identification of a new bovine syntenic group Cytogenetic and Genome Research. 56: 154-156. PMID 2055110 DOI: 10.1159/000133074  0.442
1991 Threadgill DS, Kraus JP, Krawetz SA, Womack JE. Evidence for the evolutionary origin of human chromosome 21 from comparative gene mapping in the cow and mouse Proceedings of the National Academy of Sciences of the United States of America. 88: 154-158. PMID 1986361 DOI: 10.1073/Pnas.88.1.154  0.452
1991 Threadgill DW, Womack JE. Synteny mapping of human chromosome 8 loci in cattle Animal Genetics. 22: 117-122. PMID 1909844  0.441
1991 Threadgill DS, Womack JE. The bovine pancreatic spasmolytic polypeptide gene maps to syntenic group U10: Implications for the evolution of the human breast cancer estrogen inducible locus Journal of Heredity. 82: 496-498. PMID 1795101 DOI: 10.1093/oxfordjournals.jhered.a111135  0.446
1991 Threadgill DS, Womack JE. Mapping HSA 3 loci in cattle: Additional support for the ancestral synteny of HSA 3 and 21 Genomics. 11: 1143-1148. PMID 1783381 DOI: 10.1016/0888-7543(91)90042-D  0.433
1991 Fries R, Threadgill DW, Hediger R, Gunawardana A, Blessing M, Jorcano JL, Stranzinger G, Womack JE. Mapping of bovine cytokeratin sequences to four different sites on three chromosomes. Cytogenetics and Cell Genetics. 57: 135-41. PMID 1717203 DOI: 10.1159/000133132  0.413
1991 Bishop MD, Tavakkol A, Threadgill DW, Simmen FA, Simmen RC, Davis ME, Womack JE. Somatic cell mapping and restriction fragment length polymorphism analysis of bovine insulin-like growth factor I Journal of Animal Science. 69: 4306-4311. PMID 1684360 DOI: 10.2527/1991.69114306X  0.458
1991 Threadgill DS, Womack JE. Mapping HSA10 homologous loci in cattle Cytogenetic and Genome Research. 57: 123-126. PMID 1655359 DOI: 10.1159/000133130  0.441
1990 Threadgill DW, Fries R, Faber LK, Vassart G, Gunawardana A, Stranzinger G, Womack JE. The thyroglobulin gene is syntenic with the MYC and MOS protooncogenes and carbonic anhydrase II and maps to chromosome 14 in cattle. Cytogenetics and Cell Genetics. 53: 32-6. PMID 2108842 DOI: 10.1159/000132890  0.417
1990 Threadgill DW, Adkison LR, Womack JE. Syntenic conservation between humans and cattle. II. Human chromosome 12 Genomics. 8: 29-34. PMID 2081597 DOI: 10.1016/0888-7543(90)90222-G  0.445
1990 Threadgill DW, Womack JE. Syntenic conservation between humans and cattle. I. Human chromosome 9 Genomics. 8: 22-28. PMID 2081596 DOI: 10.1016/0888-7543(90)90221-F  0.445
1990 Threadgill DW, Womack JE. Genomic analysis of the major bovine milk protein genes Nucleic Acids Research. 18: 6935-6942. PMID 1979856 DOI: 10.1093/nar/18.23.6935  0.451
1990 Threadgill DW, Wilkemeyer M, Womack JE, Ledley FD. Localization of the murine methylmalonyl CoA mutase (Mut) locus on chromosome 17 by in situ hybridization Cytogenetic and Genome Research. 53: 112-114. PMID 1973376 DOI: 10.1159/000132907  0.416
1988 Threadgill DW, Womack JE. Regional localization of mouse Abl and Mos proto-oncogenes by in situ hybridization Genomics. 3: 82-86. PMID 2906048 DOI: 10.1016/0888-7543(88)90164-4  0.45
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