| Year |
Citation |
Score |
| 2023 |
Zhao Y, Chen K, Yang H, Zhang F, Ding L, Liu Y, Zhang L, Zhang Y, Wang H, Deng Y. HLA-DR genetic polymorphisms and hepatitis B virus mutations affect the risk of hepatocellular carcinoma in Han Chinese population. Virology Journal. 20: 283. PMID 38037048 DOI: 10.1186/s12985-023-02253-2 |
0.454 |
|
| 2023 |
Li S, Chiu TY, Jin X, Cao D, Xu M, Zhu M, Zhou Q, Liu C, Zong Y, Wang S, Yu K, Zhang F, Bai M, Liu G, Liang Y, et al. Integrating genomic and multiomic data for Angelica sinensis provides insights into the evolution and biosynthesis of pharmaceutically bioactive compounds. Communications Biology. 6: 1198. PMID 38001348 DOI: 10.1038/s42003-023-05569-5 |
0.333 |
|
| 2023 |
Bustos FJ, Pandian S, Haensgen H, Zhao JP, Strouf H, Heidenreich M, Swiech L, Deverman BE, Gradinaru V, Zhang F, Constantine-Paton M. Removal of a partial genomic duplication restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer. Bmc Biology. 21: 232. PMID 37957716 DOI: 10.1186/s12915-023-01714-y |
0.57 |
|
| 2023 |
Zhang F, Jin X, Fan L, Zhao Y, Sun M, Geng X. Does subjective socioeconomic status moderate the effect of basic psychological need satisfaction on undergraduates' affective forecasting? Frontiers in Psychology. 14: 1227077. PMID 37519363 DOI: 10.3389/fpsyg.2023.1227077 |
0.463 |
|
| 2023 |
McCabe SD, Hammershaimb EA, Cheng D, Shi A, Shyr D, Shen S, Cole LD, Cataldi JR, Allen W, Probasco R, Silbermann B, Zhang F, Marsh R, Travassos MA, Lin X. Unraveling attributes of COVID-19 vaccine acceptance and uptake in the U.S.: a large nationwide study. Scientific Reports. 13: 8360. PMID 37225748 DOI: 10.1038/s41598-023-34340-3 |
0.414 |
|
| 2023 |
Bustos FJ, Pandian S, Haensgen H, Zhao JP, Strouf H, Heidenreich M, Swiech L, Deverman B, Gradinaru V, Zhang F, Constantine-Paton M. Removal of a genomic duplication by double-nicking CRISPR restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer. Biorxiv : the Preprint Server For Biology. PMID 37163068 DOI: 10.1101/2023.04.28.538685 |
0.578 |
|
| 2023 |
Jiang Q, Chen M, Yang X, Zhuge D, Yin Q, Tian D, Li L, Zhang X, Xu W, Liu S, Li F, Weng C, Lin Y, Wang H, Rao D, ... ... Zhang F, et al. Doxorubicin Detoxification in Healthy Organs Improves Tolerability to High Drug Doses for Enhanced Antitumor Therapy. Acs Nano. PMID 37022161 DOI: 10.1021/acsnano.3c00195 |
0.338 |
|
| 2023 |
Joung J, Ma S, Tay T, Geiger-Schuller KR, Kirchgatterer PC, Verdine VK, Guo B, Arias-Garcia MA, Allen WE, Singh A, Kuksenko O, Abudayyeh OO, Gootenberg JS, Fu Z, Macrae RK, ... ... Zhang F, et al. A transcription factor atlas of directed differentiation. Cell. 186: 209-229.e26. PMID 36608654 DOI: 10.1016/j.cell.2022.11.026 |
0.505 |
|
| 2022 |
Li H, Namburi P, Olson JM, Borio M, Lemieux ME, Beyeler A, Calhoon GG, Hitora-Imamura N, Coley AA, Libster A, Bal A, Jin X, Wang H, Jia C, Choudhury SR, ... ... Zhang F, et al. Neurotensin orchestrates valence assignment in the amygdala. Nature. PMID 35859170 DOI: 10.1038/s41586-022-04964-y |
0.625 |
|
| 2021 |
Kannan S, Altae-Tran H, Jin X, Madigan VJ, Oshiro R, Makarova KS, Koonin EV, Zhang F. Compact RNA editors with small Cas13 proteins. Nature Biotechnology. PMID 34462587 DOI: 10.1038/s41587-021-01030-2 |
0.326 |
|
| 2021 |
Segel M, Lash B, Song J, Ladha A, Liu CC, Jin X, Mekhedov SL, Macrae RK, Koonin EV, Zhang F. Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery. Science (New York, N.Y.). 373: 882-889. PMID 34413232 DOI: 10.1126/science.abg6155 |
0.698 |
|
| 2021 |
McCabe SD, Hammershaimb EA, Cheng D, Shi A, Shyr D, Shen S, Cole LD, Cataldi JR, Allen W, Probasco R, Silbermann B, Zhang F, Marsh R, Travassos MA, Lin X. Unraveling Attributes of COVID-19 Vaccine Hesitancy in the U.S.: A Large Nationwide Study. Medrxiv : the Preprint Server For Health Sciences. PMID 33851172 DOI: 10.1101/2021.04.05.21254918 |
0.41 |
|
| 2021 |
Qiu M, Glass Z, Chen J, Haas M, Jin X, Zhao X, Rui X, Ye Z, Li Y, Zhang F, Xu Q. Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of . Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33649229 DOI: 10.1073/pnas.2020401118 |
0.448 |
|
| 2021 |
Madison JM, Duong K, Vieux EF, Udeshi ND, Iqbal S, Requadt E, Fereshetian S, Lewis MC, Gomes AS, Pierce KA, Platt RJ, Zhang F, Campbell AJ, Lal D, Wagner FF, et al. Regulation of purine metabolism connects KCTD13 to a metabolic disorder with autistic features. Iscience. 24: 101935. PMID 33409479 DOI: 10.1016/j.isci.2020.101935 |
0.677 |
|
| 2020 |
Jin X, Simmons SK, Guo A, Shetty AS, Ko M, Nguyen L, Jokhi V, Robinson E, Oyler P, Curry N, Deangeli G, Lodato S, Levin JZ, Regev A, Zhang F, et al. In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes. Science (New York, N.Y.). 370. PMID 33243861 DOI: 10.1126/science.aaz6063 |
0.635 |
|
| 2020 |
Angrist M, Barrangou R, Baylis F, Brokowski C, Burgio G, Caplan A, Chapman CR, Church GM, Cook-Deegan R, Cwik B, Doudna JA, Evans JH, Greely HT, Hercher L, Hurlbut JB, ... ... Zhang F, et al. Reactions to the National Academies/Royal Society Report on . The Crispr Journal. 3: 332-349. PMID 33095048 DOI: 10.1089/crispr.2020.29106.man |
0.499 |
|
| 2020 |
Gao L, Altae-Tran H, Böhning F, Makarova KS, Segel M, Schmid-Burgk JL, Koob J, Wolf YI, Koonin EV, Zhang F. Diverse enzymatic activities mediate antiviral immunity in prokaryotes. Science (New York, N.Y.). 369: 1077-1084. PMID 32855333 DOI: 10.1126/Science.Aba0372 |
0.34 |
|
| 2020 |
Allen WE, Altae-Tran H, Briggs J, Jin X, McGee G, Shi A, Raghavan R, Kamariza M, Nova N, Pereta A, Danford C, Kamel A, Gothe P, Milam E, Aurambault J, ... ... Zhang F, et al. Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing. Nature Human Behaviour. PMID 32848231 DOI: 10.1038/S41562-020-00944-2 |
0.545 |
|
| 2020 |
Patchsung M, Jantarug K, Pattama A, Aphicho K, Suraritdechachai S, Meesawat P, Sappakhaw K, Leelahakorn N, Ruenkam T, Wongsatit T, Athipanyasilp N, Eiamthong B, Lakkanasirorat B, Phoodokmai T, Niljianskul N, ... ... Zhang F, et al. Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA. Nature Biomedical Engineering. PMID 32848209 DOI: 10.1038/S41551-020-00603-X |
0.367 |
|
| 2020 |
MacKay MJ, Hooker AC, Afshinnekoo E, Salit M, Kelly J, Feldstein JV, Haft N, Schenkel D, Nambi S, Cai Y, Zhang F, Church G, Dai J, Wang CL, Levy S, et al. The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing. Nature Biotechnology. PMID 32820257 DOI: 10.1038/S41587-020-0655-4 |
0.519 |
|
| 2020 |
Weiss T, Wang C, Kang X, Zhao H, Gamo ME, Starker CG, Crisp PA, Zhou P, Springer NM, Voytas DF, Zhang F. Optimization of multiplexed CRISPR/Cas9 system for highly efficient genome editing in Setaria viridis. The Plant Journal : For Cell and Molecular Biology. PMID 32786122 DOI: 10.1111/Tpj.14949 |
0.345 |
|
| 2020 |
Jin S, Fei H, Zhu Z, Luo Y, Liu J, Gao S, Zhang F, Chen YH, Wang Y, Gao C. Rationally Designed APOBEC3B Cytosine Base Editors with Improved Specificity. Molecular Cell. PMID 32721385 DOI: 10.1016/J.Molcel.2020.07.005 |
0.352 |
|
| 2020 |
Segal E, Zhang F, Lin X, King G, Shalem O, Shilo S, Allen WE, Alquaddoomi F, Altae-Tran H, Anders S, Balicer R, Bauman T, Bonilla X, Booman G, Chan AT, et al. Publisher Correction: Building an international consortium for tracking coronavirus health status. Nature Medicine. PMID 32591764 DOI: 10.1038/S41591-020-0983-4 |
0.627 |
|
| 2020 |
Allen WE, Altae-Tran H, Briggs J, Jin X, McGee G, Raghavan R, Shi A, Kamariza M, Nova N, Pereta A, Danford C, Kamel A, Gothe P, Milam E, Aurambault J, ... ... Zhang F, et al. Population-scale Longitudinal Mapping of COVID-19 Symptoms, Behavior, and Testing Identifies Contributors to Continued Disease Spread in the United States. Medrxiv : the Preprint Server For Health Sciences. PMID 32577674 DOI: 10.1101/2020.06.09.20126813 |
0.503 |
|
| 2020 |
Segal E, Zhang F, Lin X, King G, Shalem O, Shilo S, Allen WE, Alquaddoomi F, Altae-Tran H, Anders S, Balicer R, Bauman T, Bonilla X, Booman G, Chan AT, et al. Building an international consortium for tracking coronavirus health status. Nature Medicine. PMID 32488218 DOI: 10.1038/S41591-020-0929-X |
0.633 |
|
| 2020 |
Wang D, Zhang F, Gao G. CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors. Cell. 181: 136-150. PMID 32243786 DOI: 10.1016/J.Cell.2020.03.023 |
0.313 |
|
| 2020 |
Schmid-Burgk JL, Gao L, Li D, Gardner Z, Strecker J, Lash B, Zhang F. Highly Parallel Profiling of Cas9 Variant Specificity. Molecular Cell. PMID 32187529 DOI: 10.1016/J.Molcel.2020.02.023 |
0.362 |
|
| 2020 |
Sun X, Ding Y, Orr MC, Zhang F. Streamlining universal single-copy ortholog and ultraconserved element design: a case study in Collembola. Molecular Ecology Resources. PMID 32065730 DOI: 10.1111/1755-0998.13146 |
0.352 |
|
| 2019 |
Makarova KS, Wolf YI, Iranzo J, Shmakov SA, Alkhnbashi OS, Brouns SJJ, Charpentier E, Cheng D, Haft DH, Horvath P, Moineau S, Mojica FJM, Scott D, Shah SA, Siksnys V, ... ... Zhang F, et al. Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants. Nature Reviews. Microbiology. PMID 31857715 DOI: 10.1038/S41579-019-0299-X |
0.392 |
|
| 2019 |
Zetsche B, Strecker J, Abudayyeh OO, Gootenberg JS, Scott DA, Zhang F. A Survey of Genome Editing Activity for 16 Cas12a Orthologs. The Keio Journal of Medicine. PMID 31723075 DOI: 10.2302/Kjm.2019-0009-Oa |
0.49 |
|
| 2019 |
Huo X, Ji L, Zhang Y, Lv P, Cao X, Wang Q, Yan Z, Dong S, Du D, Zhang F, Wei G, Liu Y, Wen B. The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation. Molecular Cell. PMID 31677973 DOI: 10.1016/J.Molcel.2019.10.001 |
0.313 |
|
| 2019 |
Feldman D, Singh A, Schmid-Burgk JL, Carlson RJ, Mezger A, Garrity AJ, Zhang F, Blainey PC. Optical Pooled Screens in Human Cells. Cell. 179: 787-799.e17. PMID 31626775 DOI: 10.1016/J.Cell.2019.09.016 |
0.304 |
|
| 2019 |
Yang X, Zhang X, Jiao J, Zhang F, Pan Y, Wang Q, Chen Q, Cai B, Tang S, Zhou Z, Chen S, Yin H, Fu W, Luo Y, Li D, et al. Rare variants in FANCA induce premature ovarian insufficiency. Human Genetics. PMID 31535215 DOI: 10.1007/S00439-019-02059-9 |
0.301 |
|
| 2019 |
Hijazi H, Coelho FS, Gonzaga-Jauregui C, Bernardini L, Mar SS, Manning MA, Hanson-Kahn A, Naidu S, Srivastava S, Lee JA, Jones JR, Friez MJ, Alberico T, Torres B, Fang P, ... Zhang F, et al. Xq22 deletions and correlation with distinct neurological disease traits in females: further evidence for a contiguous gene syndrome. Human Mutation. PMID 31448840 DOI: 10.1002/Humu.23902 |
0.329 |
|
| 2019 |
Engreitz J, Abudayyeh O, Gootenberg J, Zhang F. CRISPR Tools for Systematic Studies of RNA Regulation. Cold Spring Harbor Perspectives in Biology. 11. PMID 31371352 DOI: 10.1101/Cshperspect.A035386 |
0.316 |
|
| 2019 |
Li P, Wu C, Guo X, Wen Y, Liu L, Liang X, Du Y, Zhang L, Ma M, Cheng S, Cheng B, Wang S, Zhang F. Integrative Analysis of Genome-Wide Association Studies and DNA Methylation Profile Identified Genetic Control Genes of DNA Methylation for Kashin-Beck Disease. Cartilage. 1947603519858748. PMID 31220921 DOI: 10.1177/1947603519858748 |
0.303 |
|
| 2019 |
Strecker J, Ladha A, Gardner Z, Schmid-Burgk JL, Makarova KS, Koonin EV, Zhang F. RNA-guided DNA insertion with CRISPR-associated transposases. Science (New York, N.Y.). PMID 31171706 DOI: 10.1126/Science.Aax9181 |
0.31 |
|
| 2019 |
Hirano S, Abudayyeh OO, Gootenberg JS, Horii T, Ishitani R, Hatada I, Zhang F, Nishimasu H, Nureki O. Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9. Nature Communications. 10: 1968. PMID 31036811 DOI: 10.1038/s41467-019-09741-6 |
0.311 |
|
| 2019 |
Jin S, Zong Y, Gao Q, Zhu Z, Wang Y, Qin P, Liang C, Wang D, Qiu JL, Zhang F, Gao C. Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice. Science (New York, N.Y.). PMID 30819931 DOI: 10.1126/Science.Aaw7166 |
0.364 |
|
| 2019 |
Strecker J, Jones S, Koopal B, Schmid-Burgk J, Zetsche B, Gao L, Makarova KS, Koonin EV, Zhang F. Engineering of CRISPR-Cas12b for human genome editing. Nature Communications. 10: 212. PMID 30670702 DOI: 10.1038/S41467-018-08224-4 |
0.367 |
|
| 2019 |
Zhang F, Ding Y, Zhou QS, Wu J, Luo A, Zhu CD. A high-quality draft genome assembly of Sinella curviseta, a soil model organism (Collembola). Genome Biology and Evolution. PMID 30668671 DOI: 10.1093/Gbe/Evz013 |
0.323 |
|
| 2019 |
Wang Q, Li D, Cai B, Chen Q, Li C, Wu Y, Jin L, Wang X, Zhang X, Zhang F. Whole-exome sequencing reveals SALL4 variants in premature ovarian insufficiency: an update on genotype-phenotype correlations. Human Genetics. PMID 30603774 DOI: 10.1007/S00439-018-1962-4 |
0.31 |
|
| 2019 |
Zhang F. Biology and Application of Genome Editing Blood. 134. DOI: 10.1182/Blood-2019-121282 |
0.323 |
|
| 2018 |
Joung J, Konermann S, Gootenberg JS, Abudayyeh OO, Platt RJ, Brigham MD, Sanjana NE, Zhang F. Author Correction: Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening. Nature Protocols. PMID 30349047 DOI: 10.1038/S41596-018-0063-0 |
0.696 |
|
| 2018 |
Tekin H, Simmons S, Cummings B, Gao L, Adiconis X, Hession CC, Ghoshal A, Dionne D, Choudhury SR, Yesilyurt V, Sanjana NE, Shi X, Lu C, Heidenreich M, Pan JQ, ... ... Zhang F, et al. Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons. Nature Biomedical Engineering. 2: 540-554. PMID 30271673 DOI: 10.1038/S41551-018-0219-9 |
0.309 |
|
| 2018 |
Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, ... Zhang F, et al. Engineered CRISPR-Cas9 nuclease with expanded targeting space. Science (New York, N.Y.). PMID 30166441 DOI: 10.1126/Science.Aas9129 |
0.353 |
|
| 2018 |
Zhang F, Voytas DF. Synthetic genomes engineered by SCRaMbLEing. Science China. Life Sciences. PMID 29951952 DOI: 10.1007/S11427-018-9325-1 |
0.302 |
|
| 2018 |
He A, Ning Y, Wen Y, Cai Y, Xu K, Cai Y, Han J, Liu L, Du Y, Liang X, Li P, Fan Q, Hao J, Wang X, Guo X, ... Zhang F, et al. Use of integrative epigenetic and mRNA expression analyses to identify significantly changed genes and functional pathways in osteoarthritic cartilage. Bone & Joint Research. 7: 343-350. PMID 29922454 DOI: 10.1302/2046-3758.75.Bjr-2017-0284.R1 |
0.319 |
|
| 2018 |
Ding M, Li P, Wen Y, Zhao Y, Cheng B, Zhang L, Ma M, Cheng S, Liu L, Du Y, Liang X, He A, Guo X, Zhang F. Integrative analysis of genome-wide association study and brain region related enhancer maps identifies biological pathways for insomnia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29883697 DOI: 10.1016/J.Pnpbp.2018.05.026 |
0.319 |
|
| 2018 |
Myers SA, Wright J, Peckner R, Kalish BT, Zhang F, Carr SA. Discovery of proteins associated with a predefined genomic locus via dCas9-APEX-mediated proximity labeling. Nature Methods. PMID 29735997 DOI: 10.1038/S41592-018-0007-1 |
0.354 |
|
| 2018 |
Canver MC, Haeussler M, Bauer DE, Orkin SH, Sanjana NE, Shalem O, Yuan GC, Zhang F, Concordet JP, Pinello L. Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments. Nature Protocols. 13: 946-986. PMID 29651054 DOI: 10.1038/Nprot.2018.005 |
0.321 |
|
| 2018 |
Wang G, Chow RD, Ye L, Guzman CD, Dai X, Dong MB, Zhang F, Sharp PA, Platt RJ, Chen S. Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening. Science Advances. 4: eaao5508. PMID 29503867 DOI: 10.1126/Sciadv.Aao5508 |
0.71 |
|
| 2018 |
Zhang F, Voytas DF. Modulating gene translational control through genome editing National Science Review. 6: 391-391. DOI: 10.1093/Nsr/Nwy123 |
0.344 |
|
| 2017 |
Fan H, Lv P, Huo X, Wu J, Wang Q, Cheng L, Liu Y, Tang Q, Zhang L, Zhang F, Zheng X, Wu H, Wen B. The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes. Genome Research. PMID 29273625 DOI: 10.1101/Gr.224576.117 |
0.329 |
|
| 2017 |
Cox DBT, Gootenberg JS, Abudayyeh OO, Franklin B, Kellner MJ, Joung J, Zhang F. RNA editing with CRISPR-Cas13. Science (New York, N.Y.). PMID 29070703 DOI: 10.1126/Science.Aaq0180 |
0.323 |
|
| 2017 |
Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Corrigendum: Engineering and optimising deaminase fusions for genome editing. Nature Communications. 8: 16169. PMID 28991237 DOI: 10.1038/Ncomms16169 |
0.768 |
|
| 2017 |
Wang W, Huang S, Hou W, Liu Y, Fan Q, He A, Wen Y, Hao J, Guo X, Zhang F. Integrative analysis of GWAS, eQTLs and meQTLs data suggests that multiple gene sets are associated with bone mineral density. Bone & Joint Research. 6: 572-576. PMID 28978616 DOI: 10.1302/2046-3758.610.Bjr-2017-0113.R1 |
0.326 |
|
| 2017 |
Jain A, Zode G, Kasetti RB, Ran FA, Yan W, Sharma TP, Bugge K, Searby CC, Fingert JH, Zhang F, Clark AF, Sheffield VC. CRISPR-Cas9-based treatment of myocilin-associated glaucoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973933 DOI: 10.1073/Pnas.1706193114 |
0.316 |
|
| 2017 |
Habib N, Avraham-Davidi I, Basu A, Burks T, Shekhar K, Hofree M, Choudhury SR, Aguet F, Gelfand E, Ardlie K, Weitz DA, Rozenblatt-Rosen O, Zhang F, Regev A. Massively parallel single-nucleus RNA-seq with DroNc-seq. Nature Methods. PMID 28846088 DOI: 10.1038/Nmeth.4407 |
0.302 |
|
| 2017 |
Chow RD, Guzman CD, Wang G, Schmidt F, Youngblood MW, Ye L, Errami Y, Dong MB, Martinez MA, Zhang S, Renauer P, Bilguvar K, Gunel M, Sharp PA, Zhang F, et al. AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma. Nature Neuroscience. PMID 28805815 DOI: 10.1038/Nn.4620 |
0.703 |
|
| 2017 |
Joung J, Engreitz JM, Konermann S, Abudayyeh OO, Verdine VK, Aguet F, Gootenberg JS, Sanjana NE, Wright JB, Fulco CP, Tseng YY, Yoon CH, Boehm JS, Lander ES, Zhang F. Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood. Nature. PMID 28792927 DOI: 10.1038/Nature23451 |
0.362 |
|
| 2017 |
Patel SJ, Sanjana NE, Kishton RJ, Eidizadeh A, Vodnala SK, Cam M, Gartner JJ, Jia L, Steinberg SM, Yamamoto TN, Merchant AS, Mehta GU, Chichura A, Shalem O, Tran E, ... Zhang F, et al. Identification of essential genes for cancer immunotherapy. Nature. PMID 28783722 DOI: 10.1038/Nature23477 |
0.319 |
|
| 2017 |
Yamano T, Zetsche B, Ishitani R, Zhang F, Nishimasu H, Nureki O. Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Molecular Cell. PMID 28781234 DOI: 10.1016/J.Molcel.2017.06.035 |
0.319 |
|
| 2017 |
Scott DA, Zhang F. Implications of human genetic variation in CRISPR-based therapeutic genome editing. Nature Medicine. PMID 28759051 DOI: 10.1038/Nm.4377 |
0.48 |
|
| 2017 |
Lu J, Lou H, Fu R, Lu D, Zhang F, Wu Z, Zhang X, Li C, Fang B, Pu F, Wei J, Wei Q, Zhang C, Wang X, Lu Y, et al. Assessing genome-wide copy number variation in the Han Chinese population. Journal of Medical Genetics. PMID 28705883 DOI: 10.1136/Jmedgenet-2017-104613 |
0.302 |
|
| 2017 |
Du Y, Wen Y, Guo X, Hao J, Wang W, He A, Fan Q, Li P, Liu L, Liang X, Zhang F. A Genome-wide Expression Association Analysis Identifies Genes and Pathways Associated with Amyotrophic Lateral Sclerosis. Cellular and Molecular Neurobiology. PMID 28639078 DOI: 10.1007/S10571-017-0512-2 |
0.311 |
|
| 2017 |
Nishimasu H, Yamano T, Gao L, Zhang F, Ishitani R, Nureki O. Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1. Molecular Cell. PMID 28595896 DOI: 10.1016/J.Molcel.2017.04.019 |
0.356 |
|
| 2017 |
Gao L, Cox DBT, Yan WX, Manteiga JC, Schneider MW, Yamano T, Nishimasu H, Nureki O, Crosetto N, Zhang F. Engineered Cpf1 variants with altered PAM specificities. Nature Biotechnology. PMID 28581492 DOI: 10.1038/Nbt.3900 |
0.379 |
|
| 2017 |
Fan Q, Wang W, Hao J, He A, Wen Y, Guo X, Wu C, Ning Y, Wang X, Wang S, Zhang F. Integrating genome-wide association study and expression quantitative trait loci data identifies multiple genes and gene set associated with neuroticism. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 28552732 DOI: 10.1016/J.Pnpbp.2017.05.017 |
0.305 |
|
| 2017 |
Tang S, Wang X, Li W, Yang X, Li Z, Liu W, Li C, Zhu Z, Wang L, Wang J, Zhang L, Sun X, Zhi E, Wang H, Li H, ... Zhang F, et al. Biallelic Mutations in CFAP43 and CFAP44 Cause Male Infertility with Multiple Morphological Abnormalities of the Sperm Flagella. American Journal of Human Genetics. PMID 28552195 DOI: 10.1016/J.Ajhg.2017.04.012 |
0.304 |
|
| 2017 |
Yan WX, Mirzazadeh R, Garnerone S, Scott D, Schneider MW, Kallas T, Custodio J, Wernersson E, Li Y, Gao L, Federova Y, Zetsche B, Zhang F, Bienko M, Crosetto N. BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks. Nature Communications. 8: 15058. PMID 28497783 DOI: 10.1038/Ncomms15058 |
0.483 |
|
| 2017 |
Platt RJ, Zhou Y, Slaymaker IM, Shetty AS, Weisbach NR, Kim JA, Sharma J, Desai M, Sood S, Kempton HR, Crabtree GR, Feng G, Zhang F. Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits. Cell Reports. 19: 335-350. PMID 28402856 DOI: 10.1016/J.Celrep.2017.03.052 |
0.704 |
|
| 2017 |
Zhang L, Wang J, Zhang C, Li D, Carvalho CM, Ji H, Xiao J, Wu Y, Zhou W, Wang H, Jin L, Luo Y, Wu X, Lupski JR, Zhang F, et al. Efficient CNV breakpoint analysis reveals unexpected structural complexity and correlation of dosage-sensitive genes with clinical severity in genomic disorders. Human Molecular Genetics. PMID 28334874 DOI: 10.1093/Hmg/Ddx102 |
0.349 |
|
| 2017 |
Joung J, Konermann S, Gootenberg JS, Abudayyeh OO, Platt RJ, Brigham MD, Sanjana NE, Zhang F. Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening. Nature Protocols. 12: 828-863. PMID 28333914 DOI: 10.1038/Nprot.2017.016 |
0.711 |
|
| 2017 |
Yamada M, Watanabe Y, Gootenberg JS, Hirano H, Ran FA, Nakane T, Ishitani R, Zhang F, Nishimasu H, Nureki O. Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems. Molecular Cell. 65: 1109-1121.e3. PMID 28306506 DOI: 10.1016/J.Molcel.2017.02.007 |
0.326 |
|
| 2017 |
Erb MA, Scott TG, Li BE, Xie H, Paulk J, Seo HS, Souza A, Roberts JM, Dastjerdi S, Buckley DL, Sanjana NE, Shalem O, Nabet B, Zeid R, Offei-Addo NK, ... Zhang F, et al. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. PMID 28241139 DOI: 10.1038/Nature21688 |
0.36 |
|
| 2017 |
Liu P, Yuan B, Carvalho CM, Wuster A, Walter K, Zhang L, Gambin T, Chong Z, Campbell IM, Coban Akdemir Z, Gelowani V, Writzl K, Bacino CA, Lindsay SJ, Withers M, ... Zhang F, et al. An Organismal CNV Mutator Phenotype Restricted to Early Human Development. Cell. 168: 830-842.e7. PMID 28235197 DOI: 10.1016/J.Cell.2017.01.037 |
0.313 |
|
| 2017 |
Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F. Erratum: Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array. Nature Biotechnology. 35: 178. PMID 28178246 DOI: 10.1038/Nbt0217-178B |
0.402 |
|
| 2017 |
Shmakov S, Smargon A, Scott D, Cox D, Pyzocha N, Yan W, Abudayyeh OO, Gootenberg JS, Makarova KS, Wolf YI, Severinov K, Zhang F, Koonin EV. Diversity and evolution of class 2 CRISPR-Cas systems. Nature Reviews. Microbiology. PMID 28111461 DOI: 10.1038/Nrmicro.2016.184 |
0.4 |
|
| 2017 |
Smargon AA, Cox DB, Pyzocha NK, Zheng K, Slaymaker IM, Gootenberg JS, Abudayyeh OA, Essletzbichler P, Shmakov S, Makarova KS, Koonin EV, Zhang F. Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28. Molecular Cell. PMID 28065598 DOI: 10.1016/J.Molcel.2016.12.023 |
0.319 |
|
| 2016 |
Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F. Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array. Nature Biotechnology. PMID 27918548 DOI: 10.1038/Nbt.3737 |
0.49 |
|
| 2016 |
Maji B, Moore CL, Zetsche B, Volz SE, Zhang F, Shoulders MD, Choudhary A. Multidimensional chemical control of CRISPR-Cas9. Nature Chemical Biology. PMID 27820801 DOI: 10.1038/Nchembio.2224 |
0.372 |
|
| 2016 |
Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Engineering and optimising deaminase fusions for genome editing. Nature Communications. 7: 13330. PMID 27804970 DOI: 10.1038/Ncomms13330 |
0.793 |
|
| 2016 |
Sanjana NE, Wright J, Zheng K, Shalem O, Fontanillas P, Joung J, Cheng C, Regev A, Zhang F. High-resolution interrogation of functional elements in the noncoding genome. Science (New York, N.Y.). 353: 1545-1549. PMID 27708104 DOI: 10.1126/Science.Aaf7613 |
0.366 |
|
| 2016 |
Jennings CG, Landman R, Zhou Y, Sharma J, Hyman J, Movshon JA, Qiu Z, Roberts AC, Roe AW, Wang X, Zhou H, Wang L, Zhang F, Desimone R, Feng G. Opportunities and challenges in modeling human brain disorders in transgenic primates. Nature Neuroscience. 19: 1123-1130. PMID 27571191 DOI: 10.1038/Nn.4362 |
0.322 |
|
| 2016 |
Shi XW, Shi BH, Lyu AL, Zhang F, Zhou TT, Guo X. Exploring Genome-wide DNA Methylation Profiles Altered in Kashin-Beck Disease Using Infinium Human Methylation 450 Bead Chips. Biomedical and Environmental Sciences : Bes. 29: 539-43. PMID 27554126 DOI: 10.3967/Bes2016.072 |
0.302 |
|
| 2016 |
Dong X, Wang X, Zhang F, Tian W. Genome-wide identification of regulatory sequences undergoing accelerated evolution in the human genome. Molecular Biology and Evolution. PMID 27401230 DOI: 10.1093/Molbev/Msw128 |
0.432 |
|
| 2016 |
Guan J, Wang D, Cao W, Zhao Y, Du R, Yuan H, Liu Q, Lan L, Zong L, Yang J, Yin Z, Han B, Zhang F, Wang Q. SIX2 haploinsufficiency causes conductive hearing loss with ptosis in humans. Journal of Human Genetics. PMID 27383657 DOI: 10.1038/Jhg.2016.86 |
0.306 |
|
| 2016 |
Duan Y, Ma G, Huang X, D'Amore PA, Zhang F, Lei H. The CRISPR/Cas9-created MDM2 T309G enhances vitreous-induced expression of MDM2 and proliferation and survival of cells. The Journal of Biological Chemistry. PMID 27246850 DOI: 10.1074/Jbc.M116.729467 |
0.315 |
|
| 2016 |
Zhu XB, Lu JQ, Zhi EL, Zhu Y, Zou SS, Zhu ZJ, Zhang F, Li Z. Association of a TDRD1 variant with spermatogenic failure susceptibility in the Han Chinese. Journal of Assisted Reproduction and Genetics. PMID 27233649 DOI: 10.1007/S10815-016-0738-9 |
0.324 |
|
| 2016 |
Wang S, Su JH, Zhang F, Zhuang X. An RNA-aptamer-based two-color CRISPR labeling system. Scientific Reports. 6: 26857. PMID 27229896 DOI: 10.1038/Srep26857 |
0.306 |
|
| 2016 |
Stoddard TJ, Clasen BM, Baltes NJ, Demorest ZL, Voytas DF, Zhang F, Luo S. Targeted Mutagenesis in Plant Cells through Transformation of Sequence-Specific Nuclease mRNA. Plos One. 11: e0154634. PMID 27176769 DOI: 10.1371/Journal.Pone.0154634 |
0.333 |
|
| 2016 |
Amit I, Baker D, Barker R, Berger B, Bertozzi C, Bhatia S, Biffi A, Demichelis F, Doudna J, Dowdy SF, Endy D, Helmstaedter M, Junca H, June C, Kamb S, ... ... Zhang F, et al. Voices of biotech. Nature Biotechnology. 34: 270-275. PMID 26963549 DOI: 10.1038/Nbt.3502 |
0.754 |
|
| 2016 |
Hirano H, Gootenberg JS, Horii T, Abudayyeh OO, Kimura M, Hsu PD, Nakane T, Ishitani R, Hatada I, Zhang F, Nishimasu H, Nureki O. Structure and Engineering of Francisella novicida Cas9. Cell. PMID 26875867 DOI: 10.1016/J.Cell.2016.01.039 |
0.327 |
|
| 2016 |
Tabebordbar M, Zhu K, Cheng JK, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ. In vivo gene editing in dystrophic mouse muscle and muscle stem cells. Science (New York, N.Y.). 351: 407-11. PMID 26721686 DOI: 10.1126/Science.Aad5177 |
0.721 |
|
| 2016 |
Heidenreich M, Zhang F. Applications of CRISPR-Cas systems in neuroscience. Nature Reviews. Neuroscience. 17: 36-44. PMID 26656253 DOI: 10.1038/Nrn.2015.2 |
0.313 |
|
| 2016 |
Nelson C, Gemberling M, Hakim CH, Ousterout DG, Thakore PI, Castellanos RM, Madhavan S, Pan X, Ran FA, Yan W, Asokan A, Zhang F, Duan D, Gersbach CA. 482. Local and Systemic Gene Editing in a Mouse Model of Duchenne Muscular Dystrophy Molecular Therapy. 24: S191. DOI: 10.1016/S1525-0016(16)33291-9 |
0.308 |
|
| 2015 |
Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy. Science (New York, N.Y.). PMID 26721684 DOI: 10.1126/Science.Aad5143 |
0.321 |
|
| 2015 |
Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F. Rationally engineered Cas9 nucleases with improved specificity. Science (New York, N.Y.). PMID 26628643 DOI: 10.1126/Science.Aad5227 |
0.51 |
|
| 2015 |
Wen Y, Wang W, Guo X, Zhang F. PAPA: a flexible tool for identifying pleiotropic pathways using genome-wide association study summaries. Bioinformatics (Oxford, England). PMID 26568630 DOI: 10.1093/Bioinformatics/Btv668 |
0.315 |
|
| 2015 |
Wen Y, Guo X, Hao J, Xiao X, Wang W, Wu C, Wang S, Yang T, Shen H, Chen X, Tan L, Tian Q, Deng HW, Zhang F. Integrative analysis of genome-wide association studies and gene expression profiles identified candidate genes for osteoporosis in Kashin-Beck disease patients. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. PMID 26462493 DOI: 10.1007/S00198-015-3364-Y |
0.315 |
|
| 2015 |
Zetsche B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der Oost J, Regev A, Koonin EV, Zhang F. Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System. Cell. PMID 26422227 DOI: 10.1016/J.Cell.2015.09.038 |
0.333 |
|
| 2015 |
Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, ... Zhang F, et al. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature. PMID 26375006 DOI: 10.1038/Nature15521 |
0.367 |
|
| 2015 |
Nishimasu H, Cong L, Yan WX, Ran FA, Zetsche B, Li Y, Kurabayashi A, Ishitani R, Zhang F, Nureki O. Crystal Structure of Staphylococcus aureus Cas9. Cell. 162: 1113-26. PMID 26317473 DOI: 10.1016/J.Cell.2015.08.007 |
0.666 |
|
| 2015 |
Zhang F, Dai L, Lin W, Wang W, Liu X, Zhang J, Yang T, Liu X, Shen H, Chen X, Tan L, Tian Q, Deng HW, Xu X, Guo X. Exome sequencing identified FGF12 as a novel candidate gene for Kashin-Beck disease. Functional & Integrative Genomics. PMID 26290467 DOI: 10.1007/S10142-015-0462-Z |
0.345 |
|
| 2015 |
Zhang F, Tsai HC, Airan RD, Stuber GD, Adamantidis AR, de Lecea L, Bonci A, Deisseroth K. Optogenetics in Freely Moving Mammals: Dopamine and Reward. Cold Spring Harbor Protocols. 2015: pdb.top086330. PMID 26240415 DOI: 10.1101/Pdb.Top086330 |
0.758 |
|
| 2015 |
Parnas O, Jovanovic M, Eisenhaure TM, Herbst RH, Dixit A, Ye CJ, Przybylski D, Platt RJ, Tirosh I, Sanjana NE, Shalem O, Satija R, Raychowdhury R, Mertins P, Carr SA, Zhang F, et al. A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks. Cell. PMID 26189680 DOI: 10.1016/J.Cell.2015.06.059 |
0.72 |
|
| 2015 |
Wen Y, Hao J, Guo X, Xiao X, Wu C, Wang S, Yang T, Shen H, Chen X, Tan L, Tian Q, Deng HW, Zhang F. SWGDT: A sliding window-based genotype dependence testing tool for genome-wide susceptibility gene scan. Journal of Biomedical Informatics. PMID 26188273 DOI: 10.1016/J.Jbi.2015.06.025 |
0.35 |
|
| 2015 |
Zhang F. CRISPR-Cas9: Prospects and Challenges. Human Gene Therapy. 26: 409-10. PMID 26176430 DOI: 10.1089/Hum.2015.29002.Fzh |
0.396 |
|
| 2015 |
Zhang L, Lu Y, Ge Y, Shi Y, Wu X, Xu Q, Li X, Lu L, Zhang F, Yao G. Interleukin-23R rs7517847 T/G Polymorphism Contributes to the Risk of Crohn's Disease in Caucasians: A Meta-Analysis. Journal of Immunology Research. 2015: 279849. PMID 26090488 DOI: 10.1155/2015/279849 |
0.478 |
|
| 2015 |
Luo S, Li J, Stoddard TJ, Baltes NJ, Demorest ZL, Clasen BM, Coffman A, Retterath A, Mathis L, Voytas DF, Zhang F. Non-transgenic plant genome editing using purified sequence-specific nucleases. Molecular Plant. PMID 26074033 DOI: 10.1016/J.Molp.2015.05.012 |
0.405 |
|
| 2015 |
Xu H, Xiao T, Chen CH, Li W, Meyer CA, Wu Q, Wu D, Cong L, Zhang F, Liu JS, Brown M, Liu XS. Sequence determinants of improved CRISPR sgRNA design. Genome Research. PMID 26063738 DOI: 10.1101/Gr.191452.115 |
0.686 |
|
| 2015 |
Ramanan V, Shlomai A, Cox DB, Schwartz RE, Michailidis E, Bhatta A, Scott DA, Zhang F, Rice CM, Bhatia SN. CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus. Scientific Reports. 5: 10833. PMID 26035283 DOI: 10.1038/Srep10833 |
0.434 |
|
| 2015 |
Li J, Stoddard TJ, Demorest ZL, Lavoie PO, Luo S, Clasen BM, Cedrone F, Ray EE, Coffman AP, Daulhac A, Yabandith A, Retterath AJ, Mathis L, Voytas DF, D'Aoust MA, Zhang F, et al. Multiplexed, targeted gene editing in Nicotiana benthamiana for glyco-engineering and monoclonal antibody production. Plant Biotechnology Journal. PMID 26011187 DOI: 10.1111/Pbi.12403 |
0.356 |
|
| 2015 |
Wang X, Ning Y, Zhang F, Yu F, Tan W, Lei Y, Wu C, Zheng J, Wang S, Yu H, Li Z, Lammi MJ, Guo X. Gene expression signature in endemic osteoarthritis by microarray analysis. International Journal of Molecular Sciences. 16: 11465-81. PMID 25997002 DOI: 10.3390/Ijms160511465 |
0.301 |
|
| 2015 |
Izpisua Belmonte JC, Callaway EM, Caddick SJ, Churchland P, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, ... Zhang F, et al. Brains, genes, and primates. Neuron. 86: 617-31. PMID 25950631 DOI: 10.1016/J.Neuron.2015.03.021 |
0.344 |
|
| 2015 |
Corrigan-Curay J, O'Reilly M, Kohn DB, Cannon PM, Bao G, Bushman FD, Carroll D, Cathomen T, Joung JK, Roth D, Sadelain M, Scharenberg AM, von Kalle C, Zhang F, Jambou R, et al. Genome editing technologies: defining a path to clinic. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 796-806. PMID 25943494 DOI: 10.1038/Mt.2015.54 |
0.361 |
|
| 2015 |
English AC, Salerno WJ, Hampton OA, Gonzaga-Jauregui C, Ambreth S, Ritter DI, Beck CR, Davis CF, Dahdouli M, Ma S, Carroll A, Veeraraghavan N, Bruestle J, Drees B, Hastie A, ... Zhang F, et al. Assessing structural variation in a personal genome-towards a human reference diploid genome. Bmc Genomics. 16: 286. PMID 25886820 DOI: 10.1186/S12864-015-1479-3 |
0.339 |
|
| 2015 |
Shalem O, Sanjana NE, Zhang F. High-throughput functional genomics using CRISPR-Cas9. Nature Reviews. Genetics. 16: 299-311. PMID 25854182 DOI: 10.1038/Nrg3899 |
0.37 |
|
| 2015 |
Clasen BM, Stoddard TJ, Luo S, Demorest ZL, Li J, Cedrone F, Tibebu R, Davison S, Ray EE, Daulhac A, Coffman A, Yabandith A, Retterath A, Haun W, Baltes NJ, ... Zhang F, et al. Improving cold storage and processing traits in potato through targeted gene knockout. Plant Biotechnology Journal. PMID 25846201 DOI: 10.1111/Pbi.12370 |
0.382 |
|
| 2015 |
Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. In vivo genome editing using Staphylococcus aureus Cas9. Nature. 520: 186-91. PMID 25830891 DOI: 10.1038/Nature14299 |
0.777 |
|
| 2015 |
Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA. Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell. 160: 1246-60. PMID 25748654 DOI: 10.1016/J.Cell.2015.02.038 |
0.447 |
|
| 2015 |
Cox DB, Platt RJ, Zhang F. Therapeutic genome editing: prospects and challenges. Nature Medicine. 21: 121-31. PMID 25654603 DOI: 10.1038/Nm.3793 |
0.729 |
|
| 2015 |
Zhang F, Xiao X, Hao J, Wang S, Wen Y, Guo X. CPAS: a trans-omics pathway analysis tool for jointly analyzing DNA copy number variations and mRNA expression profiles data. Journal of Biomedical Informatics. 53: 363-6. PMID 25546614 DOI: 10.1016/J.Jbi.2014.12.012 |
0.313 |
|
| 2015 |
Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F. Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature. 517: 583-8. PMID 25494202 DOI: 10.1038/Nature14136 |
0.369 |
|
| 2015 |
Cong L, Zhang F. Genome engineering using CRISPR-Cas9 system. Methods in Molecular Biology (Clifton, N.J.). 1239: 197-217. PMID 25408407 DOI: 10.1007/978-1-4939-1862-1_10 |
0.702 |
|
| 2015 |
Chen L, Zhou W, Zhang C, Lupski JR, Jin L, Zhang F. CNV instability associated with DNA replication dynamics: evidence for replicative mechanisms in CNV mutagenesis. Human Molecular Genetics. 24: 1574-83. PMID 25398944 DOI: 10.1093/Hmg/Ddu572 |
0.329 |
|
| 2015 |
Swiech L, Heidenreich M, Banerjee A, Habib N, Li Y, Trombetta J, Sur M, Zhang F. In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9. Nature Biotechnology. 33: 102-6. PMID 25326897 DOI: 10.1038/Nbt.3055 |
0.553 |
|
| 2015 |
Peng Z, Zhou W, Fu W, Du R, Jin L, Zhang F. Correlation between frequency of non-allelic homologous recombination and homology properties: evidence from homology-mediated CNV mutations in the human genome. Human Molecular Genetics. 24: 1225-33. PMID 25324539 DOI: 10.1093/Hmg/Ddu533 |
0.336 |
|
| 2015 |
Zhang F, Wen Y, Guo X, Zhang Y, Wang X, Yang T, Shen H, Chen X, Tian Q, Deng HW. Genome-wide association study identifies ITPR2 as a susceptibility gene for Kashin-Beck disease in Han Chinese. Arthritis & Rheumatology (Hoboken, N.J.). 67: 176-81. PMID 25303641 DOI: 10.1002/Art.38898 |
0.324 |
|
| 2015 |
Bauer DE, Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, ... Zhang F, et al. Crispr-Cas9 Saturating Mutagenesis Reveals an Achilles Heel in the BCL11A Erythroid Enhancer for Fetal Hemoglobin Induction (by Genome Editing) Blood. 126: 638-638. DOI: 10.1182/Blood.V126.23.638.638 |
0.391 |
|
| 2015 |
Zetsche B, Volz SE, Zhang F. A split-Cas9 architecture for inducible genome editing and transcription modulation Nature Biotechnology. 33: 139-142. DOI: 10.1038/Nbt.3149 |
0.324 |
|
| 2015 |
Nelson CE, Moreb DGOJNREA, Castellanos RM, Ran FA, Yan W, Zhang F, Asokan A, Gersbach CA. 397. Correction of the Dystrophin Gene By the CRISPR/Cas9 System in a Mouse Model of Muscular Dystrophy Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34006-0 |
0.402 |
|
| 2014 |
Chen L, Zhou W, Zhang L, Zhang F. Genome architecture and its roles in human copy number variation. Genomics & Informatics. 12: 136-44. PMID 25705150 DOI: 10.5808/Gi.2014.12.4.136 |
0.353 |
|
| 2014 |
Li W, Xu H, Xiao T, Cong L, Love MI, Zhang F, Irizarry RA, Liu JS, Brown M, Liu XS. MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. Genome Biology. 15: 554. PMID 25476604 DOI: 10.1186/S13059-014-0554-4 |
0.679 |
|
| 2014 |
Platt RJ, Chen S, Zhou Y, Yim MJ, Swiech L, Kempton HR, Dahlman JE, Parnas O, Eisenhaure TM, Jovanovic M, Graham DB, Jhunjhunwala S, Heidenreich M, Xavier RJ, Langer R, ... Zhang F, et al. CRISPR-Cas9 knockin mice for genome editing and cancer modeling. Cell. 159: 440-55. PMID 25263330 DOI: 10.1016/J.Cell.2014.09.014 |
0.729 |
|
| 2014 |
Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T. CRISPR-mediated direct mutation of cancer genes in the mouse liver. Nature. 514: 380-4. PMID 25119044 DOI: 10.1038/Nature13589 |
0.328 |
|
| 2014 |
Wagner JC, Platt RJ, Goldfless SJ, Zhang F, Niles JC. Efficient CRISPR-Cas9-mediated genome editing in Plasmodium falciparum. Nature Methods. 11: 915-8. PMID 25108687 DOI: 10.1038/Nmeth.3063 |
0.717 |
|
| 2014 |
Adamantidis AR, Zhang F, de Lecea L, Deisseroth K. Optogenetics: opsins and optical interfaces in neuroscience. Cold Spring Harbor Protocols. 2014: 815-22. PMID 25086025 DOI: 10.1101/Pdb.Top083329 |
0.515 |
|
| 2014 |
Adamantidis AR, Zhang F, de Lecea L, Deisseroth K. Establishing a fiber-optic-based optical neural interface. Cold Spring Harbor Protocols. 2014: 839-44. PMID 25086020 DOI: 10.1101/Pdb.Prot083337 |
0.502 |
|
| 2014 |
Sanjana NE, Shalem O, Zhang F. Improved vectors and genome-wide libraries for CRISPR screening. Nature Methods. 11: 783-784. PMID 25075903 DOI: 10.1038/Nmeth.3047 |
0.334 |
|
| 2014 |
Hsu PD, Lander ES, Zhang F. Development and applications of CRISPR-Cas9 for genome engineering. Cell. 157: 1262-78. PMID 24906146 DOI: 10.1016/J.Cell.2014.05.010 |
0.382 |
|
| 2014 |
Chen S, Xue Y, Wu X, Le C, Bhutkar A, Bell EL, Zhang F, Langer R, Sharp PA. Global microRNA depletion suppresses tumor angiogenesis. Genes & Development. 28: 1054-67. PMID 24788094 DOI: 10.1101/Gad.239681.114 |
0.561 |
|
| 2014 |
Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. Nature Biotechnology. 32: 670-6. PMID 24752079 DOI: 10.1038/Nbt.2889 |
0.664 |
|
| 2014 |
Xiao J, Zhang L, Wang J, Jiang Y, Jin L, Lu J, Jin L, Zhong C, Xu X, Zhang F. Rearrangement structure-independent strategy of CNV breakpoint analysis. Molecular Genetics and Genomics : Mgg. 289: 755-63. PMID 24737421 DOI: 10.1007/S00438-014-0850-4 |
0.336 |
|
| 2014 |
Zhang F, Wen Y, Guo X. CRISPR/Cas9 for genome editing: progress, implications and challenges. Human Molecular Genetics. 23: R40-6. PMID 24651067 DOI: 10.1093/Hmg/Ddu125 |
0.383 |
|
| 2014 |
Lee MN, Ye C, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, ... Zhang F, et al. Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science (New York, N.Y.). 343: 1246980. PMID 24604203 DOI: 10.1126/Science.1246980 |
0.303 |
|
| 2014 |
Pyzocha NK, Ran FA, Hsu PD, Zhang F. RNA-guided genome editing of mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 1114: 269-77. PMID 24557909 DOI: 10.1007/978-1-62703-761-7_17 |
0.315 |
|
| 2014 |
Nishimasu H, Ran FA, Hsu PD, Konermann S, Shehata SI, Dohmae N, Ishitani R, Zhang F, Nureki O. Crystal structure of Cas9 in complex with guide RNA and target DNA. Cell. 156: 935-49. PMID 24529477 DOI: 10.1016/J.Cell.2014.02.001 |
0.322 |
|
| 2014 |
Chen Y, Guo L, Chen J, Zhao X, Zhou W, Zhang C, Wang J, Jin L, Pei D, Zhang F. Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripotent factors on genome integrity. Bmc Genomics. 15: 79. PMID 24472662 DOI: 10.1186/1471-2164-15-79 |
0.35 |
|
| 2014 |
Zhang F, Guo X, Zhang Y, Wen Y, Wang W, Wang S, Yang T, Shen H, Chen X, Tian Q, Tan L, Deng HW. Genome-wide copy number variation study and gene expression analysis identify ABI3BP as a susceptibility gene for Kashin-Beck disease. Human Genetics. 133: 793-9. PMID 24442417 DOI: 10.1007/S00439-014-1418-4 |
0.323 |
|
| 2014 |
Klassen TL, Bomben VC, Patel A, Drabek J, Chen TT, Gu W, Zhang F, Chapman K, Lupski JR, Noebels JL, Goldman AM. High-resolution molecular genomic autopsy reveals complex sudden unexpected death in epilepsy risk profile. Epilepsia. 55: e6-12. PMID 24372310 DOI: 10.1111/Epi.12489 |
0.308 |
|
| 2014 |
Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS, Heckl D, Ebert BL, Root DE, Doench JG, Zhang F. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science (New York, N.Y.). 343: 84-7. PMID 24336571 DOI: 10.1126/Science.1247005 |
0.482 |
|
| 2014 |
Qi Y, Starker CG, Zhang F, Baltes NJ, Voytas DF. Tailor-made mutations in Arabidopsis using zinc finger nucleases. Methods in Molecular Biology (Clifton, N.J.). 1062: 193-209. PMID 24057367 DOI: 10.1007/978-1-62703-580-4_10 |
0.324 |
|
| 2014 |
Sheffer M, Hu Y, Shalem O, Sanjana N, Dhimolea E, Sarkar S, Bariteau MA, Aftab BT, Groen RWJ, Zhang F, Mitsiades CS. Genome-Scale Crispr-Cas9 Knockout Studies Reveal Mutifactorial and Functionally Overlapping Mechanisms of Myeloma Cell Resistance to Proteasome Inhibition Blood. 124: 273-273. DOI: 10.1182/Blood.V124.21.273.273 |
0.345 |
|
| 2013 |
Ran FA, Hsu PD, Wright J, Agarwala V, Scott DA, Zhang F. Genome engineering using the CRISPR-Cas9 system. Nature Protocols. 8: 2281-308. PMID 24157548 DOI: 10.1038/Nprot.2013.143 |
0.502 |
|
| 2013 |
Zhang F, Liang J, Guo X, Zhang Y, Wen Y, Li Q, Zhang Z, Ma W, Dai L, Liu X, Yang L, Wang J. Exome sequencing and functional analysis identifies a novel mutation in EXT1 gene that causes multiple osteochondromas. Plos One. 8: e72316. PMID 24009674 DOI: 10.1371/Journal.Pone.0072316 |
0.31 |
|
| 2013 |
Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y, Zhang F. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell. 154: 1380-9. PMID 23992846 DOI: 10.1016/J.Cell.2013.08.021 |
0.501 |
|
| 2013 |
Qi Y, Li X, Zhang Y, Starker CG, Baltes NJ, Zhang F, Sander JD, Reyon D, Joung JK, Voytas DF. Targeted deletion and inversion of tandemly arrayed genes in Arabidopsis thaliana using zinc finger nucleases. G3 (Bethesda, Md.). 3: 1707-15. PMID 23979943 DOI: 10.1534/G3.113.006270 |
0.329 |
|
| 2013 |
Konermann S, Brigham MD, Trevino AE, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F. Optical control of mammalian endogenous transcription and epigenetic states. Nature. 500: 472-6. PMID 23877069 DOI: 10.1038/Nature12466 |
0.805 |
|
| 2013 |
Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F. DNA targeting specificity of RNA-guided Cas9 nucleases. Nature Biotechnology. 31: 827-32. PMID 23873081 DOI: 10.1038/Nbt.2647 |
0.669 |
|
| 2013 |
Bikard D, Jiang W, Samai P, Hochschild A, Zhang F, Marraffini LA. Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. Nucleic Acids Research. 41: 7429-37. PMID 23761437 DOI: 10.1093/Nar/Gkt520 |
0.334 |
|
| 2013 |
Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell. 153: 910-8. PMID 23643243 DOI: 10.1016/J.Cell.2013.04.025 |
0.332 |
|
| 2013 |
Kempadoo KA, Tourino C, Cho SL, Magnani F, Leinninger GM, Stuber GD, Zhang F, Myers MG, Deisseroth K, de Lecea L, Bonci A. Hypothalamic neurotensin projections promote reward by enhancing glutamate transmission in the VTA. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7618-26. PMID 23637156 DOI: 10.1523/Jneurosci.2588-12.2013 |
0.48 |
|
| 2013 |
Beurdeley M, Bietz F, Li J, Thomas S, Stoddard T, Juillerat A, Zhang F, Voytas DF, Duchateau P, Silva GH. Compact designer TALENs for efficient genome engineering. Nature Communications. 4: 1762. PMID 23612303 DOI: 10.1038/Ncomms2782 |
0.438 |
|
| 2013 |
Zhou W, Zhang F, Chen X, Shen Y, Lupski JR, Jin L. Increased genome instability in human DNA segments with self-chains: homology-induced structural variations via replicative mechanisms. Human Molecular Genetics. 22: 2642-51. PMID 23474816 DOI: 10.1093/Hmg/Ddt113 |
0.356 |
|
| 2013 |
Chen X, Shen Y, Zhang F, Chiang C, Pillalamarri V, Blumenthal I, Talkowski M, Wu BL, Gusella JF. Molecular analysis of a deletion hotspot in the NRXN1 region reveals the involvement of short inverted repeats in deletion CNVs. American Journal of Human Genetics. 92: 375-86. PMID 23472757 DOI: 10.1016/J.Ajhg.2013.02.006 |
0.323 |
|
| 2013 |
Jiang W, Bikard D, Cox D, Zhang F, Marraffini LA. RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nature Biotechnology. 31: 233-9. PMID 23360965 DOI: 10.1038/Nbt.2508 |
0.366 |
|
| 2013 |
Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F. Multiplex genome engineering using CRISPR/Cas systems. Science (New York, N.Y.). 339: 819-23. PMID 23287718 DOI: 10.1126/Science.1231143 |
0.761 |
|
| 2013 |
Qi Y, Zhang Y, Zhang F, Baller JA, Cleland SC, Ryu Y, Starker CG, Voytas DF. Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways. Genome Research. 23: 547-54. PMID 23282329 DOI: 10.1101/Gr.145557.112 |
0.341 |
|
| 2013 |
Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, ... Zhang F, et al. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell. 12: 238-51. PMID 23246482 DOI: 10.1016/J.Stem.2012.11.011 |
0.344 |
|
| 2013 |
Sun Z, Liu P, Jia X, Withers MA, Jin L, Lupski JR, Zhang F. Replicative mechanisms of CNV formation preferentially occur as intrachromosomal events: evidence from Potocki-Lupski duplication syndrome. Human Molecular Genetics. 22: 749-56. PMID 23161748 DOI: 10.1093/Hmg/Dds482 |
0.305 |
|
| 2013 |
Zhang Y, Zhang F, Li X, Baller JA, Qi Y, Starker CG, Bogdanove AJ, Voytas DF. Transcription activator-like effector nucleases enable efficient plant genome engineering. Plant Physiology. 161: 20-7. PMID 23124327 DOI: 10.1104/Pp.112.205179 |
0.362 |
|
| 2012 |
Zhang F, Guo X, Wu S, Han J, Liu Y, Shen H, Deng HW. Genome-wide pathway association studies of multiple correlated quantitative phenotypes using principle component analyses. Plos One. 7: e53320. PMID 23285279 DOI: 10.1371/Journal.Pone.0053320 |
0.32 |
|
| 2012 |
Zhang YP, Deng FY, Yang TL, Zhang F, Chen XD, Shen H, Zhu XZ, Tian Q, Deng HW. Genome-wide association study identified CNP12587 region underlying height variation in Chinese females. Plos One. 7: e44292. PMID 22957059 DOI: 10.1371/Journal.Pone.0044292 |
0.328 |
|
| 2012 |
Hsu PD, Zhang F. Dissecting neural function using targeted genome engineering technologies. Acs Chemical Neuroscience. 3: 603-610. PMID 22896804 DOI: 10.1021/Cn300089K |
0.361 |
|
| 2012 |
Lee SH, Kwan AC, Zhang S, Phoumthipphavong V, Flannery JG, Masmanidis SC, Taniguchi H, Huang ZJ, Zhang F, Boyden ES, Deisseroth K, Dan Y. Activation of specific interneurons improves V1 feature selectivity and visual perception. Nature. 488: 379-83. PMID 22878719 DOI: 10.1038/Nature11312 |
0.5 |
|
| 2012 |
Cong L, Zhou R, Kuo YC, Cunniff M, Zhang F. Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains. Nature Communications. 3: 968. PMID 22828628 DOI: 10.1038/Ncomms1962 |
0.685 |
|
| 2012 |
Zhang F, Guo X, Wang W, Wu S, Ma W, Yan H. Expression profile analysis of mycotoxin-related genes in cartilage with endemic osteochondropathy Kashin-Beck Disease. Bmc Musculoskeletal Disorders. 13: 130. PMID 22828367 DOI: 10.1186/1471-2474-13-130 |
0.308 |
|
| 2012 |
Briggs AW, Rios X, Chari R, Yang L, Zhang F, Mali P, Church GM. Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Research. 40: e117. PMID 22740649 DOI: 10.1093/Nar/Gks624 |
0.751 |
|
| 2012 |
Mei Y, Zhang F. Molecular tools and approaches for optogenetics. Biological Psychiatry. 71: 1033-8. PMID 22480664 DOI: 10.1016/J.Biopsych.2012.02.019 |
0.315 |
|
| 2012 |
Kato HE, Zhang F, Yizhar O, Ramakrishnan C, Nishizawa T, Hirata K, Ito J, Aita Y, Tsukazaki T, Hayashi S, Hegemann P, Maturana AD, Ishitani R, Deisseroth K, Nureki O. Crystal structure of the channelrhodopsin light-gated cation channel. Nature. 482: 369-74. PMID 22266941 DOI: 10.1038/Nature10870 |
0.686 |
|
| 2012 |
Watanabe HC, Welke K, Schneider F, Tsunoda S, Zhang F, Deisseroth K, Hegemann P, Elstner M. Structural model of channelrhodopsin. The Journal of Biological Chemistry. 287: 7456-66. PMID 22241469 DOI: 10.1074/Jbc.M111.320309 |
0.484 |
|
| 2012 |
Sanjana NE, Cong L, Zhou Y, Cunniff MM, Feng G, Zhang F. A transcription activator-like effector toolbox for genome engineering. Nature Protocols. 7: 171-92. PMID 22222791 DOI: 10.1038/Nprot.2011.431 |
0.692 |
|
| 2012 |
Kato HE, Zhang F, Yizhar O, Ramakrishnan C, Nishizawa T, Hirata K, Ito J, Aita Y, Tsukazaki T, Hayashi S, Hegemann P, Maturana AD, Ishitani R, Deisseroth K, Nureki O. 1PT128 Crystal Structure of a light-gated cation channel, channeirhodopsin(The 50th Annual Meeting of the Biophysical Society of Japan) Seibutsu Butsuri. 52: S90. DOI: 10.2142/Biophys.52.S90_3 |
0.641 |
|
| 2011 |
Zhang F, Vierock J, Yizhar O, Fenno LE, Tsunoda S, Kianianmomeni A, Prigge M, Berndt A, Cushman J, Polle J, Magnuson J, Hegemann P, Deisseroth K. The microbial opsin family of optogenetic tools. Cell. 147: 1446-57. PMID 22196724 DOI: 10.1016/J.Cell.2011.12.004 |
0.782 |
|
| 2011 |
Liu P, Lacaria M, Zhang F, Withers M, Hastings PJ, Lupski JR. Frequency of nonallelic homologous recombination is correlated with length of homology: evidence that ectopic synapsis precedes ectopic crossing-over. American Journal of Human Genetics. 89: 580-8. PMID 21981782 DOI: 10.1016/J.Ajhg.2011.09.009 |
0.332 |
|
| 2011 |
Mateo C, Avermann M, Gentet LJ, Zhang F, Deisseroth K, Petersen CC. In vivo optogenetic stimulation of neocortical excitatory neurons drives brain-state-dependent inhibition. Current Biology : Cb. 21: 1593-602. PMID 21945274 DOI: 10.1016/J.Cub.2011.08.028 |
0.49 |
|
| 2011 |
Liu P, Erez A, Nagamani SC, Dhar SU, Kołodziejska KE, Dharmadhikari AV, Cooper ML, Wiszniewska J, Zhang F, Withers MA, Bacino CA, Campos-Acevedo LD, Delgado MR, Freedenberg D, Garnica A, et al. Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements. Cell. 146: 889-903. PMID 21925314 DOI: 10.1016/J.Cell.2011.07.042 |
0.322 |
|
| 2011 |
Gutierrez R, Lobo MK, Zhang F, de Lecea L. Neural integration of reward, arousal, and feeding: recruitment of VTA, lateral hypothalamus, and ventral striatal neurons. Iubmb Life. 63: 824-30. PMID 21901814 DOI: 10.1002/Iub.539 |
0.312 |
|
| 2011 |
Hancock CN, Zhang F, Floyd K, Richardson AO, Lafayette P, Tucker D, Wessler SR, Parrott WA. The rice miniature inverted repeat transposable element mPing is an effective insertional mutagen in soybean. Plant Physiology. 157: 552-62. PMID 21844309 DOI: 10.1104/Pp.111.181206 |
0.321 |
|
| 2011 |
Zhang F, Guo X, Wang W, Yan H, Li C. Genome-wide gene expression analysis suggests an important role of hypoxia in the pathogenesis of endemic osteochondropathy Kashin-Beck disease. Plos One. 6: e22983. PMID 21829570 DOI: 10.1371/Journal.Pone.0022983 |
0.321 |
|
| 2011 |
Adamantidis AR, Tsai HC, Boutrel B, Zhang F, Stuber GD, Budygin EA, Touriño C, Bonci A, Deisseroth K, de Lecea L. Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10829-35. PMID 21795535 DOI: 10.1523/Jneurosci.2246-11.2011 |
0.593 |
|
| 2011 |
Stuber GD, Sparta DR, Stamatakis AM, van Leeuwen WA, Hardjoprajitno JE, Cho S, Tye KM, Kempadoo KA, Zhang F, Deisseroth K, Bonci A. Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. Nature. 475: 377-80. PMID 21716290 DOI: 10.1038/Nature10194 |
0.686 |
|
| 2011 |
Zhu H, Shang D, Sun M, Choi S, Liu Q, Hao J, Figuera LE, Zhang F, Choy KW, Ao Y, Liu Y, Zhang XL, Yue F, Wang MR, Jin L, et al. X-linked congenital hypertrichosis syndrome is associated with interchromosomal insertions mediated by a human-specific palindrome near SOX3. American Journal of Human Genetics. 88: 819-26. PMID 21636067 DOI: 10.1016/J.Ajhg.2011.05.004 |
0.311 |
|
| 2011 |
Curtin SJ, Zhang F, Sander JD, Haun WJ, Starker C, Baltes NJ, Reyon D, Dahlborg EJ, Goodwin MJ, Coffman AP, Dobbs D, Joung JK, Voytas DF, Stupar RM. Targeted mutagenesis of duplicated genes in soybean with zinc-finger nucleases. Plant Physiology. 156: 466-73. PMID 21464476 DOI: 10.1104/Pp.111.172981 |
0.342 |
|
| 2011 |
Yizhar O, Fenno L, Zhang F, Hegemann P, Diesseroth K. Microbial opsins: a family of single-component tools for optical control of neural activity. Cold Spring Harbor Protocols. 2011: top102. PMID 21363959 DOI: 10.1101/Pdb.Top102 |
0.775 |
|
| 2011 |
Zhang F, Guo X, Deng H. Multilocus association testing of quantitative traits based on partial least-squares analysis. Plos One. 6. PMID 21304821 DOI: 10.1371/Journal.Pone.0016739 |
0.317 |
|
| 2011 |
Stroh A, Tsai HC, Wang LP, Zhang F, Kressel J, Aravanis A, Santhanam N, Deisseroth K, Konnerth A, Schneider MB. Tracking stem cell differentiation in the setting of automated optogenetic stimulation. Stem Cells (Dayton, Ohio). 29: 78-88. PMID 21280159 DOI: 10.1002/Stem.558 |
0.619 |
|
| 2011 |
Reyon D, Kirkpatrick JR, Sander JD, Zhang F, Voytas DF, Joung JK, Dobbs D, Coffman CR. ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms. Bmc Genomics. 12: 83. PMID 21276248 DOI: 10.1186/1471-2164-12-83 |
0.356 |
|
| 2011 |
Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nature Biotechnology. 29: 149-53. PMID 21248753 DOI: 10.1038/Nbt.1775 |
0.776 |
|
| 2011 |
Carvalho CM, Zhang F, Lupski JR. Structural variation of the human genome: mechanisms, assays, and role in male infertility. Systems Biology in Reproductive Medicine. 57: 3-16. PMID 21210740 DOI: 10.3109/19396368.2010.527427 |
0.313 |
|
| 2011 |
Zhang F, Voytas DF. Targeted mutagenesis in Arabidopsis using zinc-finger nucleases. Methods in Molecular Biology (Clifton, N.J.). 701: 167-77. PMID 21181530 DOI: 10.1007/978-1-61737-957-4_9 |
0.325 |
|
| 2011 |
Sander JD, Dahlborg EJ, Goodwin MJ, Cade L, Zhang F, Cifuentes D, Curtin SJ, Blackburn JS, Thibodeau-Beganny S, Qi Y, Pierick CJ, Hoffman E, Maeder ML, Khayter C, Reyon D, et al. Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA). Nature Methods. 8: 67-9. PMID 21151135 DOI: 10.1038/Nmeth.1542 |
0.356 |
|
| 2010 |
Fu W, Zhang F, Wang Y, Gu X, Jin L. Identification of copy number variation hotspots in human populations. American Journal of Human Genetics. 87: 494-504. PMID 20920665 DOI: 10.1016/J.Ajhg.2010.09.006 |
0.331 |
|
| 2010 |
Hoshaw JP, Unger-Wallace E, Zhang F, Voytas DF. A transient assay for monitoring zinc finger nuclease activity at endogenous plant gene targets. Methods in Molecular Biology (Clifton, N.J.). 649: 299-313. PMID 20680843 DOI: 10.1007/978-1-60761-753-2_19 |
0.334 |
|
| 2010 |
Christian M, Cermak T, Doyle EL, Schmidt C, Zhang F, Hummel A, Bogdanove AJ, Voytas DF. Targeting DNA double-strand breaks with TAL effector nucleases. Genetics. 186: 757-61. PMID 20660643 DOI: 10.1534/Genetics.110.120717 |
0.307 |
|
| 2010 |
Gonzaga-Jauregui C, Zhang F, Towne CF, Batish SD, Lupski JR. GJB1/Connexin 32 whole gene deletions in patients with X-linked Charcot-Marie-Tooth disease. Neurogenetics. 11: 465-70. PMID 20532933 DOI: 10.1007/S10048-010-0247-4 |
0.305 |
|
| 2010 |
Zhang F, Maeder ML, Unger-Wallace E, Hoshaw JP, Reyon D, Christian M, Li X, Pierick CJ, Dobbs D, Peterson T, Joung JK, Voytas DF. High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases. Proceedings of the National Academy of Sciences of the United States of America. 107: 12028-33. PMID 20508152 DOI: 10.1073/Pnas.0914991107 |
0.314 |
|
| 2010 |
Zhang F, Seeman P, Liu P, Weterman MA, Gonzaga-Jauregui C, Towne CF, Batish SD, De Vriendt E, De Jonghe P, Rautenstrauss B, Krause KH, Khajavi M, Posadka J, Vandenberghe A, Palau F, et al. Mechanisms for nonrecurrent genomic rearrangements associated with CMT1A or HNPP: rare CNVs as a cause for missing heritability. American Journal of Human Genetics. 86: 892-903. PMID 20493460 DOI: 10.1016/J.Ajhg.2010.05.001 |
0.363 |
|
| 2010 |
Lee JH, Durand R, Gradinaru V, Zhang F, Goshen I, Kim DS, Fenno LE, Ramakrishnan C, Deisseroth K. Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. Nature. 465: 788-92. PMID 20473285 DOI: 10.1038/Nature09108 |
0.771 |
|
| 2010 |
Gradinaru V, Zhang F, Ramakrishnan C, Mattis J, Prakash R, Diester I, Goshen I, Thompson KR, Deisseroth K. Molecular and cellular approaches for diversifying and extending optogenetics. Cell. 141: 154-65. PMID 20303157 DOI: 10.1016/J.Cell.2010.02.037 |
0.784 |
|
| 2010 |
Lupski JR, Reid JG, Gonzaga-Jauregui C, Rio Deiros D, Chen DC, Nazareth L, Bainbridge M, Dinh H, Jing C, Wheeler DA, McGuire AL, Zhang F, Stankiewicz P, Halperin JJ, Yang C, et al. Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. The New England Journal of Medicine. 362: 1181-91. PMID 20220177 DOI: 10.1056/Nejmoa0908094 |
0.345 |
|
| 2010 |
Zhang F, Gradinaru V, Adamantidis AR, Durand R, Airan RD, de Lecea L, Deisseroth K. Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures. Nature Protocols. 5: 439-56. PMID 20203662 DOI: 10.1038/Nprot.2009.226 |
0.785 |
|
| 2010 |
Zhang L, Guo YF, Liu YZ, Liu YJ, Xiong DH, Liu XG, Wang L, Yang TL, Lei SF, Guo Y, Yan H, Pei YF, Zhang F, Papasian CJ, Recker RR, et al. Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1572-80. PMID 20200951 DOI: 10.1002/Jbmr.36 |
0.305 |
|
| 2010 |
Zhang F, Potocki L, Sampson JB, Liu P, Sanchez-Valle A, Robbins-Furman P, Navarro AD, Wheeler PG, Spence JE, Brasington CK, Withers MA, Lupski JR. Identification of uncommon recurrent Potocki-Lupski syndrome-associated duplications and the distribution of rearrangement types and mechanisms in PTLS. American Journal of Human Genetics. 86: 462-70. PMID 20188345 DOI: 10.1016/J.Ajhg.2010.02.001 |
0.345 |
|
| 2010 |
Cardin JA, Carlén M, Meletis K, Knoblich U, Zhang F, Deisseroth K, Tsai LH, Moore CI. Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2. Nature Protocols. 5: 247-54. PMID 20134425 DOI: 10.1038/Nprot.2009.228 |
0.544 |
|
| 2010 |
Carvalho CM, Zhang F, Lupski JR. Evolution in health and medicine Sackler colloquium: Genomic disorders: a window into human gene and genome evolution. Proceedings of the National Academy of Sciences of the United States of America. 107: 1765-71. PMID 20080665 DOI: 10.1073/Pnas.0906222107 |
0.354 |
|
| 2010 |
Guo Y, Tan LJ, Lei SF, Yang TL, Chen XD, Zhang F, Chen Y, Pan F, Yan H, Liu X, Tian Q, Zhang ZX, Zhou Q, Qiu C, Dong SS, et al. Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. Plos Genetics. 6: e1000806. PMID 20072603 DOI: 10.1371/Journal.Pgen.1000806 |
0.307 |
|
| 2010 |
Lee JH, Durand R, Gradinaru V, Zhang F, Goshen I, Kim DS, Fenno LE, Ramakrishnan C, Deisseroth K. Lee et al. reply Nature. 468: E4-E5. DOI: 10.1038/Nature09533 |
0.767 |
|
| 2009 |
Naito K, Zhang F, Tsukiyama T, Saito H, Hancock CN, Richardson AO, Okumoto Y, Tanisaka T, Wessler SR. Unexpected consequences of a sudden and massive transposon amplification on rice gene expression. Nature. 461: 1130-4. PMID 19847266 DOI: 10.1038/Nature08479 |
0.356 |
|
| 2009 |
Zhang J, Laiwalla F, Kim JA, Urabe H, Van Wagenen R, Song YK, Connors BW, Zhang F, Deisseroth K, Nurmikko AV. Integrated device for optical stimulation and spatiotemporal electrical recording of neural activity in light-sensitized brain tissue. Journal of Neural Engineering. 6: 055007. PMID 19721185 DOI: 10.1088/1741-2560/6/5/055007 |
0.522 |
|
| 2009 |
Zhang F, Gu W, Hurles ME, Lupski JR. Copy number variation in human health, disease, and evolution. Annual Review of Genomics and Human Genetics. 10: 451-481. PMID 19715442 DOI: 10.1146/Annurev.Genom.9.081307.164217 |
0.356 |
|
| 2009 |
Nagamani SC, Zhang F, Shchelochkov OA, Bi W, Ou Z, Scaglia F, Probst FJ, Shinawi M, Eng C, Hunter JV, Sparagana S, Lagoe E, Fong CT, Pearson M, Doco-Fenzy M, et al. Microdeletions including YWHAE in the Miller-Dieker syndrome region on chromosome 17p13.3 result in facial dysmorphisms, growth restriction, and cognitive impairment. Journal of Medical Genetics. 46: 825-33. PMID 19584063 DOI: 10.1136/Jmg.2009.067637 |
0.317 |
|
| 2009 |
Zhang F, Carvalho CMB, Lupski JR. Complex human chromosomal and genomic rearrangements Trends in Genetics. 25: 298-307. PMID 19560228 DOI: 10.1016/J.Tig.2009.05.005 |
0.334 |
|
| 2009 |
Zhang F, Khajavi M, Connolly AM, Towne CF, Batish SD, Lupski JR. The DNA replication FoSTeS/MMBIR mechanism can generate genomic, genic and exonic complex rearrangements in humans. Nature Genetics. 41: 849-53. PMID 19543269 DOI: 10.1038/Ng.399 |
0.363 |
|
| 2009 |
Sohal VS, Zhang F, Yizhar O, Deisseroth K. Parvalbumin neurons and gamma rhythms enhance cortical circuit performance. Nature. 459: 698-702. PMID 19396159 DOI: 10.1038/Nature07991 |
0.757 |
|
| 2009 |
Cardin JA, Carlén M, Meletis K, Knoblich U, Zhang F, Deisseroth K, Tsai LH, Moore CI. Driving fast-spiking cells induces gamma rhythm and controls sensory responses. Nature. 459: 663-7. PMID 19396156 DOI: 10.1038/Nature08002 |
0.498 |
|
| 2009 |
Tsai HC, Zhang F, Adamantidis A, Stuber GD, Bonci A, de Lecea L, Deisseroth K. Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science (New York, N.Y.). 324: 1080-4. PMID 19389999 DOI: 10.1126/Science.1168878 |
0.597 |
|
| 2009 |
Zimmermann G, Wang LP, Vaughan AG, Manoli DS, Zhang F, Deisseroth K, Baker BS, Scott MP. Manipulation of an innate escape response in Drosophila: photoexcitation of acj6 neurons induces the escape response. Plos One. 4: e5100. PMID 19340304 DOI: 10.1371/Journal.Pone.0005100 |
0.496 |
|
| 2009 |
Carvalho CM, Zhang F, Liu P, Patel A, Sahoo T, Bacino CA, Shaw C, Peacock S, Pursley A, Tavyev YJ, Ramocki MB, Nawara M, Obersztyn E, Vianna-Morgante AM, Stankiewicz P, et al. Complex rearrangements in patients with duplications of MECP2 can occur by fork stalling and template switching. Human Molecular Genetics. 18: 2188-203. PMID 19324899 DOI: 10.1093/Hmg/Ddp151 |
0.347 |
|
| 2009 |
Bi W, Sapir T, Shchelochkov OA, Zhang F, Withers MA, Hunter JV, Levy T, Shinder V, Peiffer DA, Gunderson KL, Nezarati MM, Shotts VA, Amato SS, Savage SK, Harris DJ, et al. Increased LIS1 expression affects human and mouse brain development. Nature Genetics. 41: 168-77. PMID 19136950 DOI: 10.1038/Ng.302 |
0.312 |
|
| 2009 |
Yan J, Zhang F, Brundage E, Scheuerle A, Lanpher B, Erickson RP, Powis Z, Robinson HB, Trapane PL, Stachiw-Hietpas D, Keppler-Noreuil KM, Lalani SR, Sahoo T, Chinault AC, Patel A, et al. Genomic duplication resulting in increased copy number of genes encoding the sister chromatid cohesion complex conveys clinical consequences distinct from Cornelia de Lange. Journal of Medical Genetics. 46: 626-34. PMID 19052029 DOI: 10.1136/Jmg.2008.062471 |
0.361 |
|
| 2008 |
Gu W, Zhang F, Lupski JR. Mechanisms for human genomic rearrangements Pathogenetics. 1: 4-4. PMID 19014668 DOI: 10.1186/1755-8417-1-4 |
0.347 |
|
| 2008 |
Zhao S, Cunha C, Zhang F, Liu Q, Gloss B, Deisseroth K, Augustine GJ, Feng G. Improved expression of halorhodopsin for light-induced silencing of neuronal activity. Brain Cell Biology. 36: 141-54. PMID 18931914 DOI: 10.1007/S11068-008-9034-7 |
0.515 |
|
| 2008 |
Schneider MB, Gradinaru V, Zhang F, Deisseroth K. Controlling neuronal activity. The American Journal of Psychiatry. 165: 562. PMID 18450936 DOI: 10.1176/Appi.Ajp.2008.08030444 |
0.679 |
|
| 2008 |
Zhang F, Prigge M, Beyrière F, Tsunoda SP, Mattis J, Yizhar O, Hegemann P, Deisseroth K. Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri. Nature Neuroscience. 11: 631-3. PMID 18432196 DOI: 10.1038/Nn.2120 |
0.771 |
|
| 2007 |
Gradinaru V, Thompson KR, Zhang F, Mogri M, Kay K, Schneider MB, Deisseroth K. Targeting and readout strategies for fast optical neural control in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14231-8. PMID 18160630 DOI: 10.1523/Jneurosci.3578-07.2007 |
0.757 |
|
| 2007 |
Hwang RY, Zhong L, Xu Y, Johnson T, Zhang F, Deisseroth K, Tracey WD. Nociceptive neurons protect Drosophila larvae from parasitoid wasps. Current Biology : Cb. 17: 2105-16. PMID 18060782 DOI: 10.1016/J.Cub.2007.11.029 |
0.472 |
|
| 2007 |
Adamantidis AR, Zhang F, Aravanis AM, Deisseroth K, de Lecea L. Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature. 450: 420-4. PMID 17943086 DOI: 10.1038/Nature06310 |
0.485 |
|
| 2007 |
Aravanis AM, Wang LP, Zhang F, Meltzer LA, Mogri MZ, Schneider MB, Deisseroth K. An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology. Journal of Neural Engineering. 4: S143-56. PMID 17873414 DOI: 10.1088/1741-2560/4/3/S02 |
0.799 |
|
| 2007 |
Zhang F, Aravanis AM, Adamantidis A, de Lecea L, Deisseroth K. Circuit-breakers: optical technologies for probing neural signals and systems. Nature Reviews. Neuroscience. 8: 577-81. PMID 17643087 DOI: 10.1038/nrn2192 |
0.458 |
|
| 2007 |
Yang G, Zhang F, Hancock CN, Wessler SR. Transposition of the rice miniature inverted repeat transposable element mPing in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America. 104: 10962-7. PMID 17578919 DOI: 10.1073/Pnas.0702080104 |
0.327 |
|
| 2007 |
Wang H, Peca J, Matsuzaki M, Matsuzaki K, Noguchi J, Qiu L, Wang D, Zhang F, Boyden E, Deisseroth K, Kasai H, Hall WC, Feng G, Augustine GJ. High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 8143-8. PMID 17483470 DOI: 10.1073/Pnas.0700384104 |
0.518 |
|
| 2007 |
Zhang F, Wang LP, Brauner M, Liewald JF, Kay K, Watzke N, Wood PG, Bamberg E, Nagel G, Gottschalk A, Deisseroth K. Multimodal fast optical interrogation of neural circuitry. Nature. 446: 633-9. PMID 17410168 DOI: 10.1038/Nature05744 |
0.541 |
|
| 2007 |
Hwang RY, Zhong L, Xu Y, Johnson T, Zhang F, Deisseroth K, Tracey WD. Nociceptive Neurons Protect Drosophila Larvae from Parasitoid Wasps (DOI:10.1016/j.cub.2007.11.029) Current Biology. 17: 2183. DOI: 10.1016/J.Cub.2007.12.018 |
0.464 |
|
| 2006 |
Zhang J, Zhang F, Peterson T. Transposition of reversed Ac element ends generates novel chimeric genes in maize. Plos Genetics. 2: e164. PMID 17029561 DOI: 10.1371/Journal.Pgen.0020164 |
0.302 |
|
| 2006 |
Zhang F, Wang LP, Boyden ES, Deisseroth K. Channelrhodopsin-2 and optical control of excitable cells. Nature Methods. 3: 785-92. PMID 16990810 DOI: 10.1038/Nmeth936 |
0.531 |
|
| 2006 |
Zhang F, Peterson T. Gene conversion between direct noncoding repeats promotes genetic and phenotypic diversity at a regulatory locus of Zea mays (L.). Genetics. 174: 753-62. PMID 16816430 DOI: 10.1534/Genetics.105.053942 |
0.334 |
|
| 2005 |
Boyden ES, Zhang F, Bamberg E, Nagel G, Deisseroth K. Millisecond-timescale, genetically targeted optical control of neural activity. Nature Neuroscience. 8: 1263-8. PMID 16116447 DOI: 10.1038/Nn1525 |
0.546 |
|
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