| Year |
Citation |
Score |
| 2021 |
Winters ND, Bedse G, Astafyev AA, Patrick TA, Altemus M, Morgan AJ, Mukerjee S, Johnson KD, Mahajan VR, Uddin MJ, Kingsley PJ, Centanni SW, Siciliano CA, Samuels DC, Marnett LJ, et al. Targeting diacylglycerol lipase reduces alcohol consumption in preclinical models. The Journal of Clinical Investigation. PMID 34292886 DOI: 10.1172/JCI146861 |
0.752 |
|
| 2020 |
Uddin MJ, Xu S, Crews BC, Aleem AM, Ghebreselasie K, Banerjee S, Marnett LJ. Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors. Acs Medicinal Chemistry Letters. 11: 1881-1885. PMID 33062168 DOI: 10.1021/Acsmedchemlett.9B00555 |
0.318 |
|
| 2020 |
Reyes-Uribe L, Wu W, Gelincik O, Bommi PV, Francisco-Cruz A, Solis LM, Lynch PM, Lim R, Stoffel EM, Kanth P, Samadder NJ, Mork ME, Taggart MW, Milne GL, Marnett LJ, et al. Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa. Gut. PMID 32641470 DOI: 10.1136/Gutjnl-2020-320946 |
0.481 |
|
| 2020 |
Rouzer CA, Marnett LJ. Structural and Chemical Biology of the Interaction of Cyclooxygenase with Substrates and Non-Steroidal Anti-Inflammatory Drugs. Chemical Reviews. PMID 32609495 DOI: 10.1021/Acs.Chemrev.0C00215 |
0.331 |
|
| 2020 |
Uribe LR, Wu W, Gelincik O, Bommi PV, Francisco-Cruz A, Solis LM, Lynch PM, Lim R, Stoffel E, Kanth P, Samadder NJ, Mork ME, Taggart MW, Milne GL, Marnett LJ, et al. Abstract CT111: Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Ct111 |
0.487 |
|
| 2019 |
Kingsley PJ, Rouzer CA, Morgan AJ, Patel S, Marnett LJ. Aspects of Prostaglandin Glycerol Ester Biology. Advances in Experimental Medicine and Biology. 1161: 77-88. PMID 31562623 DOI: 10.1007/978-3-030-21735-8_8 |
0.793 |
|
| 2019 |
Wepy JA, Galligan JJ, Kingsley PJ, Xu S, Goodman MC, Tallman KA, Rouzer CA, Marnett LJ. Erratum: Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling. Journal of Lipid Research. 60: 1345. PMID 31262966 DOI: 10.1194/Jlr.Err119000139 |
0.785 |
|
| 2019 |
Xu S, Uddin MJ, Banerjee S, Duggan K, Musee J, Kiefer JR, Ghebreselasie K, Rouzer CA, Marnett LJ. Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site. The Journal of Biological Chemistry. PMID 31000626 DOI: 10.1074/Jbc.Ra119.007405 |
0.311 |
|
| 2018 |
Bruehl S, Burns JW, Morgan A, Koltyn K, Gupta R, Buvanendran A, Edwards D, Chont M, Kingsley PJ, Marnett L, Stone A, Patel S. The association between endogenous opioid function and morphine responsiveness: a moderating role for endocannabinoids. Pain. PMID 30562268 DOI: 10.1097/J.Pain.0000000000001447 |
0.753 |
|
| 2018 |
Wepy JA, Galligan JJ, Kingsley PJ, Xu S, Goodman MC, Tallman KA, Rouzer CA, Marnett LJ. Lysophospholipases Cooperate to Mediate Lipid Homeostasis and Lysophospholipid Signaling. Journal of Lipid Research. PMID 30482805 DOI: 10.1194/jlr.M087890 |
0.786 |
|
| 2018 |
Liu Y, Ji L, Eno M, Kudalkar S, Li A, Schimpgen M, Benchama O, Morales P, Xu S, Hurst DP, Wu S, Mohammad KA, Wood JT, Zvonok N, Papahatjis D, ... ... Marnett LJ, et al. (R)-N-(1-Methyl-2-hydroxyethyl)-13-(S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. Journal of Medicinal Chemistry. PMID 30196704 DOI: 10.1021/Acs.Jmedchem.8B00611 |
0.307 |
|
| 2018 |
Galligan JJ, Wepy JA, Streeter MD, Kingsley PJ, Mitchener MM, Wauchope OR, Beavers WN, Rose KL, Wang T, Spiegel DA, Marnett LJ. Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks. Proceedings of the National Academy of Sciences of the United States of America. PMID 30150385 DOI: 10.1073/pnas.1802901115 |
0.767 |
|
| 2018 |
Morgan A, Kingsley PJ, Mitchener MM, Altemus M, Patrick T, Gaulden A, Marnett LJ, Patel S. Detection of cyclooxygenase-2-derived oxygenation products of the endogenous cannabinoid 2-arachidonoylglycerol in mouse brain. Acs Chemical Neuroscience. PMID 29722963 DOI: 10.1021/Acschemneuro.7B00499 |
0.785 |
|
| 2018 |
Wauchope OR, Mitchener MM, Beavers WN, Galligan JJ, Camarillo JM, Sanders WD, Kingsley PJ, Shim HN, Blackwell T, Luong T, deCaestecker M, Fessel JP, Marnett LJ. Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA. Nucleic Acids Research. PMID 29438559 DOI: 10.1093/Nar/Gky089 |
0.735 |
|
| 2018 |
Goodman MC, Xu S, Rouzer CA, Banerjee S, Ghebreselasie K, Migliore M, Piomelli D, Marnett LJ. Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site. The Journal of Biological Chemistry. PMID 29326169 DOI: 10.1074/jbc.M117.802058 |
0.361 |
|
| 2018 |
Uribe LR, Lin R, Stoffel EM, Samadder NJ, Lynch P, Kanth P, Milne G, Marnett LJ, Sepeda V, Liu DD, You YN, Vornik LA, Lee JJ, Richmond E, Umar A, et al. Abstract CT065: A phase Ib biomarker trial of naproxen in patients at risk for DNA mismatch repair deficient colorectal cancer Clinical Trials. DOI: 10.1158/1538-7445.Am2018-Ct065 |
0.466 |
|
| 2017 |
Beavers WN, Rose KL, Galligan JJ, Mitchener MM, Rouzer CA, Tallman KA, Lamberson CR, Wang X, Hill S, Ivanova PT, Brown HA, Zhang B, Porter NA, Marnett LJ. Protein Modification by Endogenously Generated Lipid Electrophiles: Mitochondria as the Source and Target. Acs Chemical Biology. PMID 28613820 DOI: 10.1021/Acschembio.7B00480 |
0.784 |
|
| 2017 |
Pulley JM, Shirey-Rice JK, Lavieri RR, Jerome RN, Zaleski NM, Aronoff DM, Bastarache L, Niu X, Holroyd KJ, Roden DM, Skaar EP, Niswender CM, Marnett LJ, Lindsley CW, Ekstrom LB, et al. Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics. Assay and Drug Development Technologies. PMID 28379727 DOI: 10.1089/Adt.2016.772 |
0.478 |
|
| 2016 |
Galligan JJ, Kingsley PJ, Wauchope O, Mitchener MM, Camarillo JM, Wepy JA, Harris PS, Fritz KS, Marnett LJ. Quantitative Analysis and Discovery of Lysine and Arginine Modifications (QuARKMod). Analytical Chemistry. PMID 27982582 DOI: 10.1021/Acs.Analchem.6B04105 |
0.771 |
|
| 2016 |
Camarillo JM, Ullery JC, Rose KL, Marnett LJ. Electrophilic Modification of PKM2 by 4-Hydroxynonenal and 4-Oxononenal Results in Protein Cross-Linking and Kinase Inhibition. Chemical Research in Toxicology. PMID 27978618 DOI: 10.1021/Acs.Chemrestox.6B00374 |
0.355 |
|
| 2016 |
Galligan JJ, Marnett LJ. Histone adduction and its functional impact on epigenetics. Chemical Research in Toxicology. PMID 27930886 DOI: 10.1021/Acs.Chemrestox.6B00379 |
0.55 |
|
| 2016 |
Uddin MJ, Crews BC, Xu S, Ghebreselasie K, Daniel CK, Kingsley PJ, Banerjee S, Marnett LJ. Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors. Acs Chemical Biology. PMID 27588346 DOI: 10.1021/Acschembio.6B00560 |
0.323 |
|
| 2016 |
Boutaud O, Sosa IR, Amin T, Oram D, Adler D, Hwang HS, Crews B, Milne GL, Harris BK, Hoeksema MD, Knowllmann BC, Lammers PE, Marnett LJ, Massion PP, Oates JA. Inhibition of the biosynthesis of prostaglandin E2 by low dose aspirin: implications for adenocarcinoma metastasis. Cancer Prevention Research (Philadelphia, Pa.). PMID 27554763 DOI: 10.1158/1940-6207.Capr-16-0094 |
0.495 |
|
| 2016 |
Kudalkar SN, Kingsley PJ, Marnett LJ. Assay of Endocannabinoid Oxidation by Cyclooxygenase-2. Methods in Molecular Biology (Clifton, N.J.). 1412: 205-15. PMID 27245906 DOI: 10.1007/978-1-4939-3539-0_21 |
0.357 |
|
| 2016 |
Hinz C, Aldrovandi M, Uhlson C, Marnett LJ, Longhurst HJ, Warner TD, Alam S, Slatter DA, Lauder SN, Allen-Redpath K, Collins PW, Murphy RC, Thomas CP, O'Donnell VB. Human platelets utilize cycloxygenase-1 to generate dioxolane A3, a neutrophil activating eicosanoid. The Journal of Biological Chemistry. PMID 27129261 DOI: 10.1074/Jbc.M115.700609 |
0.303 |
|
| 2016 |
Mont S, Davies SS, Roberts Second LJ, Mernaugh RL, McDonald WH, Segal BH, Zackert W, Kropski JA, Blackwell TS, Sekhar KR, Galligan JJ, Massion PP, Marnett LJ, Travis EL, Freeman ML. Accumulation of isolevuglandin-modified protein in normal and fibrotic lung. Scientific Reports. 6: 24919. PMID 27118599 DOI: 10.1038/Srep24919 |
0.531 |
|
| 2016 |
Camarillo JM, Rose KL, Galligan JJ, Xu S, Marnett LJ. Covalent modification of CDK2 by 4-hydroxynonenal as a mechanism of inhibition of cell cycle progression. Chemical Research in Toxicology. PMID 26910110 DOI: 10.1021/Acs.Chemrestox.5B00485 |
0.551 |
|
| 2016 |
Mont S, Davies SS, Roberts LJ, Mernaugh RL, McDonald WH, Segal BH, Kropski JA, Blackwell TS, Sekhar KR, Galligan JJ, Marnett LJ, Freeman ML. Abstract 3050: Proteotoxic isolevuglandins are a central feature of radiation-induced pulmonary injury Cancer Research. 76: 3050-3050. DOI: 10.1158/1538-7445.Am2016-3050 |
0.524 |
|
| 2015 |
Konkle ME, Blobaum AL, Moth CW, Prusakiewicz JJ, Xu S, Ghebreselasie K, Akingbade D, Jacobs AT, Rouzer CA, Lybrand TP, Marnett LJ. A Conservative Secondary Shell Substitution In Cyclooxygenase-2 Reduces Inhibition by Indomethacin Amides and Esters via Altered Enzyme Dynamics. Biochemistry. PMID 26704937 DOI: 10.1021/Acs.Biochem.5B01222 |
0.336 |
|
| 2015 |
Wauchope OR, Beavers WN, Galligan JJ, Mitchener MM, Kingsley PJ, Marnett LJ. Nuclear Oxidation of a Major Peroxidation DNA Adduct, M1dG, in the Genome. Chemical Research in Toxicology. PMID 26469224 DOI: 10.1021/Acs.Chemrestox.5B00340 |
0.751 |
|
| 2015 |
Mitchener MM, Hermanson DJ, Shockley EM, Brown HA, Lindsley CW, Reese J, Rouzer CA, Lopez CF, Marnett LJ. Competition and allostery govern substrate selectivity of cyclooxygenase-2. Proceedings of the National Academy of Sciences of the United States of America. 112: 12366-71. PMID 26392530 DOI: 10.1073/Pnas.1507307112 |
0.324 |
|
| 2015 |
Blobaum AL, Xu S, Rowlinson SW, Duggan KC, Banerjee S, Kudalkar SN, Birmingham WR, Ghebreselasie K, Marnett LJ. Action at a distance: mutations of peripheral residues transform rapid reversible inhibitors to slow, tight binders of cyclooxygenase-2. The Journal of Biological Chemistry. 290: 12793-803. PMID 25825493 DOI: 10.1074/Jbc.M114.635987 |
0.303 |
|
| 2015 |
Aluise CD, Camarillo JM, Shimozu Y, Galligan JJ, Rose KL, Tallman KA, Marnett LJ. Site-specific, intramolecular cross-linking of Pin1 active site residues by the lipid electrophile 4-oxo-2-nonenal. Chemical Research in Toxicology. 28: 817-27. PMID 25739016 DOI: 10.1021/Acs.Chemrestox.5B00038 |
0.568 |
|
| 2015 |
Kudalkar SN, Nikas SP, Kingsley PJ, Xu S, Galligan JJ, Rouzer CA, Banerjee S, Ji L, Eno MR, Makriyannis A, Marnett LJ. 13-Methylarachidonic acid is a positive allosteric modulator of endocannabinoid oxygenation by cyclooxygenase. The Journal of Biological Chemistry. 290: 7897-909. PMID 25648895 DOI: 10.1074/Jbc.M114.634014 |
0.547 |
|
| 2015 |
Camarillo JM, Ullery JC, Rose KL, Marnett LJ. Modification of PKM2 by Lipid Electrophiles Inhibits Glycolytic Metabolism Free Radical Biology and Medicine. 87: S144. DOI: 10.1016/J.Freeradbiomed.2015.10.370 |
0.308 |
|
| 2015 |
Mont S, Davies SS, Roberts II LJ, Hayes McDonald W, Mernaugh RL, Segal BH, Zackert W, Konjeti SR, Kropski JA, Galligan JJ, Blackwell TS, Massion PP, Marnett LJ, Freeman ML. Identification of Isoketal-Modified Proteins and Genes That Regulate Their Formation Free Radical Biology and Medicine. 87: S139. DOI: 10.1016/J.Freeradbiomed.2015.10.359 |
0.499 |
|
| 2015 |
Galligan JJ, Mitchener M, Wang T, Wauchope O, Rose K, Spiegel D, Marnett L. Histones Are Major Targets for Modification by Glucose-Derived Methylglyoxal Free Radical Biology and Medicine. 87: S24. DOI: 10.1016/J.Freeradbiomed.2015.10.066 |
0.497 |
|
| 2014 |
Xu S, Rouzer CA, Marnett LJ. Oxicams, a class of nonsteroidal anti-inflammatory drugs and beyond. Iubmb Life. 66: 803-11. PMID 25537198 DOI: 10.1002/Iub.1334 |
0.313 |
|
| 2014 |
Uddin MJ, Elleman AV, Ghebreselasie K, Daniel CK, Crews BC, Nance KD, Huda T, Marnett LJ. Design of Fluorine-Containing 3,4-Diarylfuran-2(5H)-ones as Selective COX-1 Inhibitors. Acs Medicinal Chemistry Letters. 5: 1254-8. PMID 25408841 DOI: 10.1021/Ml500344J |
0.306 |
|
| 2014 |
Manna JD, Wepy JA, Hsu KL, Chang JW, Cravatt BF, Marnett LJ. Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells. The Journal of Biological Chemistry. 289: 33741-53. PMID 25301951 DOI: 10.1074/Jbc.M114.582353 |
0.776 |
|
| 2014 |
Shuck SC, Wauchope OR, Rose KL, Kingsley PJ, Rouzer CA, Shell SM, Sugitani N, Chazin WJ, Zagol-Ikapitte I, Boutaud O, Oates JA, Galligan JJ, Beavers WN, Marnett LJ. Protein modification by adenine propenal. Chemical Research in Toxicology. 27: 1732-42. PMID 25211669 DOI: 10.1021/Tx500218G |
0.757 |
|
| 2014 |
Galligan JJ, Rose KL, Beavers WN, Hill S, Tallman KA, Tansey WP, Marnett LJ. Stable histone adduction by 4-oxo-2-nonenal: a potential link between oxidative stress and epigenetics. Journal of the American Chemical Society. 136: 11864-6. PMID 25099620 DOI: 10.1021/Ja503604T |
0.747 |
|
| 2014 |
Beavers WN, Serwa R, Shimozu Y, Tallman KA, Vaught M, Dalvie ED, Marnett LJ, Porter NA. ω-Alkynyl lipid surrogates for polyunsaturated fatty acids: free radical and enzymatic oxidations. Journal of the American Chemical Society. 136: 11529-39. PMID 25034362 DOI: 10.1021/Ja506038V |
0.789 |
|
| 2014 |
Rietjens IM, Cohen SM, Fukushima S, Gooderham NJ, Hecht S, Marnett LJ, Smith RL, Adams TB, Bastaki M, Harman CG, Taylor SV. Impact of structural and metabolic variations on the toxicity and carcinogenicity of hydroxy- and alkoxy-substituted allyl- and propenylbenzenes. Chemical Research in Toxicology. 27: 1092-103. PMID 24857813 DOI: 10.1021/Tx500109S |
0.3 |
|
| 2014 |
Hermanson DJ, Gamble-George JC, Marnett LJ, Patel S. Substrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation. Trends in Pharmacological Sciences. 35: 358-67. PMID 24845457 DOI: 10.1016/J.Tips.2014.04.006 |
0.337 |
|
| 2014 |
Codreanu SG, Ullery JC, Zhu J, Tallman KA, Beavers WN, Porter NA, Marnett LJ, Zhang B, Liebler DC. Alkylation damage by lipid electrophiles targets functional protein systems. Molecular & Cellular Proteomics : McP. 13: 849-59. PMID 24429493 DOI: 10.1074/Mcp.M113.032953 |
0.735 |
|
| 2014 |
Shuck SC, Rose KL, Marnett LJ. Mass spectrometric methods for the analysis of nucleoside-protein cross-links: application to oxopropenyl-deoxyadenosine. Chemical Research in Toxicology. 27: 136-46. PMID 24359270 DOI: 10.1021/Tx400384E |
0.305 |
|
| 2014 |
Beavers WN, Rose KL, Galligan JJ, Tallman KA, Hill SS, Milne SB, Myers DS, Ivanova P, Wang X, Zhang B, Brown HA, Porter NA, Marnett LJ. Mitochondrial Proteins Are Highly Adducted Targets of Endogenously Generated Lipid Electrophiles in LPS-Activated RAW264.7 Macrophages Free Radical Biology and Medicine. 76: S145-S146. DOI: 10.1016/J.Freeradbiomed.2014.10.548 |
0.765 |
|
| 2014 |
Wauchope O, Galligan J, Kingsley P, Marnett L. Nuclear Metabolism of an Inflammation-Linked DNA Adduct in the Genome Free Radical Biology and Medicine. 76: S160-S161. DOI: 10.1016/J.Freeradbiomed.2014.10.074 |
0.507 |
|
| 2014 |
Galligan JJ, Beavers WN, Rose K, Marnett LJ. Epigenetics and Oxidative Stress: Establishing a Link through Histone Adduction Free Radical Biology and Medicine. 76: S157. DOI: 10.1016/J.Freeradbiomed.2014.10.062 |
0.732 |
|
| 2013 |
Windsor MA, Valk PL, Xu S, Banerjee S, Marnett LJ. Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxib. Bioorganic & Medicinal Chemistry Letters. 23: 5860-4. PMID 24060487 DOI: 10.1016/J.Bmcl.2013.08.097 |
0.324 |
|
| 2013 |
Hermanson DJ, Hartley ND, Gamble-George J, Brown N, Shonesy BC, Kingsley PJ, Colbran RJ, Reese J, Marnett LJ, Patel S. Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation. Nature Neuroscience. 16: 1291-8. PMID 23912944 DOI: 10.1038/Nn.3480 |
0.327 |
|
| 2013 |
Aldrovandi M, Hammond VJ, Podmore H, Hornshaw M, Clark SR, Marnett LJ, Slatter DA, Murphy RC, Collins PW, O'Donnell VB. Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation. Journal of Lipid Research. 54: 3085-97. PMID 23883581 DOI: 10.1194/Jlr.M041533 |
0.314 |
|
| 2013 |
Soares CO, Boiani M, Marnett LJ, Bechara EJ. Cytotoxicity of 1,4-diamino-2-butanone, a putrescine analogue, to RKO cells: mechanism and redox imbalance. Free Radical Research. 47: 672-82. PMID 23758064 DOI: 10.3109/10715762.2013.814126 |
0.356 |
|
| 2013 |
Blobaum AL, Uddin MJ, Felts AS, Crews BC, Rouzer CA, Marnett LJ. The 2'-Trifluoromethyl Analogue of Indomethacin Is a Potent and Selective COX-2 Inhibitor. Acs Medicinal Chemistry Letters. 4: 486-490. PMID 23687559 DOI: 10.1021/Ml400066A |
0.309 |
|
| 2013 |
Mohebati A, Milne GL, Zhou XK, Duffield-Lillico AJ, Boyle JO, Knutson A, Bosworth BP, Kingsley PJ, Marnett LJ, Brown PH, Akpa EG, Szabo E, Dannenberg AJ. Effect of zileuton and celecoxib on urinary LTE4 and PGE-M levels in smokers. Cancer Prevention Research (Philadelphia, Pa.). 6: 646-55. PMID 23682075 DOI: 10.1158/1940-6207.Capr-13-0083 |
0.508 |
|
| 2013 |
Uddin MJ, Crews BC, Ghebreselasie K, Marnett LJ. Design, synthesis, and structure-activity relationship studies of fluorescent inhibitors of cycloxygenase-2 as targeted optical imaging agents. Bioconjugate Chemistry. 24: 712-23. PMID 23488616 DOI: 10.1021/Bc300693W |
0.321 |
|
| 2013 |
Tallman KA, Armstrong MD, Milne SB, Marnett LJ, Brown HA, Porter NA. Cobalt carbonyl complexes as probes for alkyne-tagged lipids. Journal of Lipid Research. 54: 859-68. PMID 23307946 DOI: 10.1194/Jlr.D033332 |
0.505 |
|
| 2013 |
Laube M, Neumann W, Scholz M, Lönnecke P, Crews B, Marnett LJ, Pietzsch J, Kniess T, Hey-Hawkins E. 2-Carbaborane-3-phenyl-1H-indoles--synthesis via McMurry reaction and cyclooxygenase (COX) inhibition activity. Chemmedchem. 8: 329-35. PMID 23303738 DOI: 10.1002/Cmdc.201200455 |
0.312 |
|
| 2013 |
Aluise CD, Rose K, Boiani M, Reyzer ML, Manna JD, Tallman K, Porter NA, Marnett LJ. Peptidyl-prolyl cis/trans-isomerase A1 (Pin1) is a target for modification by lipid electrophiles. Chemical Research in Toxicology. 26: 270-9. PMID 23231502 DOI: 10.1021/Tx300449G |
0.549 |
|
| 2013 |
Galligan JJ, Rose KL, Beavers WN, Aluise CD, Shuck SC, Marnett LJ. Abstract A12: Alkylation of histones by 4-oxo-2-nonenal as a novel modification linked to oxidative stress Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A12 |
0.757 |
|
| 2013 |
Galligan JJ, Rose KL, Kudalkar SN, Beavers WN, Aluise CD, Marnett LJ. 4-oxo-2-nonenal Adduction of Chromatin: a Novel Post-Translational Modification to Histones Free Radical Biology and Medicine. 65: S151. DOI: 10.1016/J.Freeradbiomed.2013.10.776 |
0.729 |
|
| 2013 |
Shuck S, Galligan J, Wauchope O, Kingsley P, Rose K, Marnett L. Chemical Characterization of Protein Modification by Base Propenal Free Radical Biology and Medicine. 65: S148. DOI: 10.1016/J.Freeradbiomed.2013.10.770 |
0.507 |
|
| 2013 |
Aluise CD, Marnett LJ. Pin1 is a Target for Oxidative Modification by the Lipid Electrophiles 4-Hydroxynonenal and 4- Oxononenal Free Radical Biology and Medicine. 65: S139. DOI: 10.1016/J.Freeradbiomed.2013.10.743 |
0.301 |
|
| 2013 |
Shimozu Y, Beavers WN, Tallman KA, Porter NA, Marnett LJ. Protein Adduction by Keto Linoleic Acid, 13-Oxooctadecadienoic Acid (13-KODE) Free Radical Biology and Medicine. 65: S57. DOI: 10.1016/J.Freeradbiomed.2013.10.526 |
0.734 |
|
| 2012 |
Windsor MA, Hermanson DJ, Kingsley PJ, Xu S, Crews BC, Ho W, Keenan CM, Banerjee S, Sharkey KA, Marnett LJ. Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes. Acs Medicinal Chemistry Letters. 3: 759-763. PMID 22984634 DOI: 10.1021/Ml3001616 |
0.332 |
|
| 2012 |
Musee J, Marnett LJ. Prostaglandin H synthase-2-catalyzed oxygenation of 2-arachidonoylglycerol is more sensitive to peroxide tone than oxygenation of arachidonic acid. The Journal of Biological Chemistry. 287: 37383-94. PMID 22942274 DOI: 10.1074/Jbc.M112.381202 |
0.326 |
|
| 2012 |
Xu S, Mueser TC, Marnett LJ, Funk MO. Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis. Structure (London, England : 1993). 20: 1490-7. PMID 22795085 DOI: 10.1016/J.Str.2012.06.003 |
0.313 |
|
| 2012 |
Scholz M, Blobaum AL, Marnett LJ, Hey-Hawkins E. Ortho-carbaborane derivatives of indomethacin as cyclooxygenase (COX)-2 selective inhibitors. Bioorganic & Medicinal Chemistry. 20: 4830-7. PMID 22748709 DOI: 10.1016/J.Bmc.2012.05.063 |
0.313 |
|
| 2012 |
Ullery JC, Marnett LJ. Protein modification by oxidized phospholipids and hydrolytically released lipid electrophiles: Investigating cellular responses. Biochimica Et Biophysica Acta. 1818: 2424-35. PMID 22562025 DOI: 10.1016/J.Bbamem.2012.04.014 |
0.347 |
|
| 2012 |
Marnett LJ. Inflammation and cancer: chemical approaches to mechanisms, imaging, and treatment. The Journal of Organic Chemistry. 77: 5224-38. PMID 22515568 DOI: 10.1021/Jo300214D |
0.333 |
|
| 2012 |
Liedtke AJ, Crews BC, Daniel CM, Blobaum AL, Kingsley PJ, Ghebreselasie K, Marnett LJ. Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold. Journal of Medicinal Chemistry. 55: 2287-300. PMID 22263894 DOI: 10.1021/Jm201528B |
0.35 |
|
| 2012 |
Uddin MJ, Crews BC, Ghebreselasie K, Blobaum AL, Duggan KC, Xu S, Kingsley P, Cekanova M, Marnett LJ. Abstract CN04-02: A novel approach to biomolecular imaging of COX-2 Cancer Prevention Research. 5: CN04-02-CN04-02. DOI: 10.1158/1940-6207.Prev-12-Cn04-02 |
0.32 |
|
| 2012 |
Adeniji A, Liedkte A, Byrns MC, Chen M, Jin Y, Christianson D, Marnett LJ, Penning TM. Abstract B16: Development of potent and selective indomethacin analogs for the inhibition of AKR1C3 (type 5 17 -hydroxysteroid dehydrogenase) in CRPC Cancer Research. 72: B16-B16. DOI: 10.1158/1538-7445.Prca2012-B16 |
0.323 |
|
| 2012 |
Aluise CD, Marnett LJ. Abstract 2062: Peptidylprolyl cis/trans isomerase A1 (Pin1) is modified by lipid electrophiles generated during oxidative stress Cancer Research. 72: 2062-2062. DOI: 10.1158/1538-7445.Am2012-2062 |
0.372 |
|
| 2011 |
Rouzer CA, Marnett LJ. Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling pathways. Chemical Reviews. 111: 5899-921. PMID 21923193 DOI: 10.1021/Cr2002799 |
0.383 |
|
| 2011 |
Scholz M, Blobaum AL, Marnett LJ, Hey-Hawkins E. Synthesis and evaluation of carbaborane derivatives of indomethacin as cyclooxygenase inhibitors. Bioorganic & Medicinal Chemistry. 19: 3242-8. PMID 21524587 DOI: 10.1016/J.Bmc.2011.03.054 |
0.317 |
|
| 2011 |
McGrath CE, Tallman KA, Porter NA, Marnett LJ. Structure-activity analysis of diffusible lipid electrophiles associated with phospholipid peroxidation: 4-hydroxynonenal and 4-oxononenal analogues. Chemical Research in Toxicology. 24: 357-70. PMID 21291287 DOI: 10.1021/Tx100323M |
0.53 |
|
| 2011 |
Trostchansky A, Bonilla L, Thomas CP, O'Donnell VB, Marnett LJ, Radi R, Rubbo H. Nitroarachidonic acid, a novel peroxidase inhibitor of prostaglandin endoperoxide H synthases 1 and 2. The Journal of Biological Chemistry. 286: 12891-900. PMID 21266582 DOI: 10.1074/Jbc.M110.154518 |
0.329 |
|
| 2011 |
Plastaras JP, Marnett LJ. Measurement of a malondialdehyde-DNA adduct. Current Protocols in Toxicology. Unit3.2. PMID 20941700 DOI: 10.1002/0471140856.Tx0302S00 |
0.321 |
|
| 2010 |
Eoff RL, McGrath CE, Maddukuri L, Salamanca-Pinzón SG, Marquez VE, Marnett LJ, Guengerich FP, Egli M. Selective modulation of DNA polymerase activity by fixed-conformation nucleoside analogues. Angewandte Chemie (International Ed. in English). 49: 7481-5. PMID 20814997 DOI: 10.1002/Anie.201003168 |
0.305 |
|
| 2010 |
Duggan KC, Walters MJ, Musee J, Harp JM, Kiefer JR, Oates JA, Marnett LJ. Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. The Journal of Biological Chemistry. 285: 34950-9. PMID 20810665 DOI: 10.1074/Jbc.M110.162982 |
0.31 |
|
| 2010 |
Duggan KC, Musee J, Marnett LJ. Peroxidase active site activity assay. Methods in Molecular Biology (Clifton, N.J.). 644: 55-65. PMID 20645165 DOI: 10.1007/978-1-59745-364-6_6 |
0.325 |
|
| 2010 |
Jacobs AT, Marnett LJ. Systems analysis of protein modification and cellular responses induced by electrophile stress. Accounts of Chemical Research. 43: 673-83. PMID 20218676 DOI: 10.1021/Ar900286Y |
0.356 |
|
| 2010 |
Richie-Jannetta R, Nirodi CS, Crews BC, Woodward DF, Wang JW, Duff PT, Marnett LJ. Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells. Prostaglandins & Other Lipid Mediators. 92: 19-24. PMID 20152925 DOI: 10.1016/J.Prostaglandins.2010.01.003 |
0.307 |
|
| 2010 |
Milne SB, Tallman KA, Serwa R, Rouzer CA, Armstrong MD, Marnett LJ, Lukehart CM, Porter NA, Brown HA. Capture and release of alkyne-derivatized glycerophospholipids using cobalt chemistry. Nature Chemical Biology. 6: 205-207. PMID 20098428 DOI: 10.1038/Nchembio.311 |
0.728 |
|
| 2010 |
Marnett LJ, Jacobs A, Vila A, McGrath C, Boiani M, Ullery J, Tallman K, Porter NA, Zhang B, Liebler DC. Systems Approaches to Establishing the Relationship Between Protein Modification and Cellular Responses by Lipid Electrophiles Free Radical Biology and Medicine. 49: S8. DOI: 10.1016/J.Freeradbiomed.2010.10.677 |
0.531 |
|
| 2010 |
Turman MV, Marnett LJ. Prostaglandin endoperoxide synthases: Structure, function, and synthesis of novel lipid signaling molecules Comprehensive Natural Products Ii: Chemistry and Biology. 1: 35-63. DOI: 10.1016/B978-008045382-8.00028-9 |
0.8 |
|
| 2009 |
Tallman KA, Vila A, Porter NA, Marnett LJ. Measuring electrophile stress. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit17.11. PMID 23045010 DOI: 10.1002/0471140856.Tx1711S40 |
0.522 |
|
| 2009 |
Turman MV, Kingsley PJ, Marnett LJ. Characterization of an AM404 analogue, N-(3-hydroxyphenyl)arachidonoylamide, as a substrate and inactivator of prostaglandin endoperoxide synthase. Biochemistry. 48: 12233-41. PMID 19928795 DOI: 10.1021/Bi901181Z |
0.799 |
|
| 2009 |
Prusakiewicz JJ, Duggan KC, Rouzer CA, Marnett LJ. Differential sensitivity and mechanism of inhibition of COX-2 oxygenation of arachidonic acid and 2-arachidonoylglycerol by ibuprofen and mefenamic acid. Biochemistry. 48: 7353-5. PMID 19603831 DOI: 10.1021/Bi900999Z |
0.309 |
|
| 2009 |
Eoff RL, Stafford JB, Szekely J, Rizzo CJ, Egli M, Guengerich FP, Marnett LJ. Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct. Biochemistry. 48: 7079-88. PMID 19492857 DOI: 10.1021/Bi9003588 |
0.339 |
|
| 2009 |
Konkle ME, Hargrove TY, Kleshchenko YY, von Kries JP, Ridenour W, Uddin MJ, Caprioli RM, Marnett LJ, Nes WD, Villalta F, Waterman MR, Lepesheva GI. Indomethacin amides as a novel molecular scaffold for targeting Trypanosoma cruzi sterol 14alpha-demethylase. Journal of Medicinal Chemistry. 52: 2846-53. PMID 19354253 DOI: 10.1021/Jm801643B |
0.304 |
|
| 2009 |
Marnett LJ. Mechanisms of cyclooxygenase-2 inhibition and cardiovascular side effects: the plot thickens. Cancer Prevention Research (Philadelphia, Pa.). 2: 288-90. PMID 19336721 DOI: 10.1158/1940-6207.Capr-09-0033 |
0.303 |
|
| 2009 |
Knutson CG, Rubinson EH, Akingbade D, Anderson CS, Stec DF, Petrova KV, Kozekov ID, Guengerich FP, Rizzo CJ, Marnett LJ. Oxidation and glycolytic cleavage of etheno and propano DNA base adducts. Biochemistry. 48: 800-9. PMID 19132922 DOI: 10.1021/Bi801654J |
0.316 |
|
| 2009 |
Rouzer CA, Marnett LJ. Cyclooxygenases: structural and functional insights. Journal of Lipid Research. 50: S29-34. PMID 18952571 DOI: 10.1194/Jlr.R800042-Jlr200 |
0.32 |
|
| 2009 |
Uddin MJ, Crews BC, Blobaum AL, Kingsley PJ, Ghebreselasie K, Saleh SS, Clanton JA, Baldwin RM, Marnett LJ. Synthesis and evaluation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents Journal of Labelled Compounds and Radiopharmaceuticals. 52: 387-393. DOI: 10.1002/Jlcr.1615 |
0.324 |
|
| 2008 |
VanderVeen LA, Harris TM, Jen-Jacobson L, Marnett LJ. Formation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRI. Chemical Research in Toxicology. 21: 1733-8. PMID 18690724 DOI: 10.1021/Tx800092G |
0.311 |
|
| 2008 |
Felts AS, Siegel BS, Young SM, Moth CW, Lybrand TP, Dannenberg AJ, Marnett LJ, Subbaramaiah K. Sulindac derivatives that activate the peroxisome proliferator-activated receptor gamma but lack cyclooxygenase inhibition. Journal of Medicinal Chemistry. 51: 4911-9. PMID 18665581 DOI: 10.1021/Jm700969C |
0.315 |
|
| 2008 |
Knutson CG, Skipper PL, Liberman RG, Tannenbaum SR, Marnett LJ. Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M1dG {3-(2-deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin-10(3H)-one}, by accelerator mass spectrometry. Chemical Research in Toxicology. 21: 1290-4. PMID 18461974 DOI: 10.1021/Tx800049V |
0.303 |
|
| 2008 |
Turman MV, Kingsley PJ, Rouzer CA, Cravatt BF, Marnett LJ. Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine. Biochemistry. 47: 3917-25. PMID 18311922 DOI: 10.1021/Bi702530Z |
0.793 |
|
| 2008 |
Rouzer CA, Marnett LJ. Non-redundant functions of cyclooxygenases: Oxygenation of endocannabinoids Journal of Biological Chemistry. 283: 8065-8069. PMID 18250160 DOI: 10.1074/Jbc.R800005200 |
0.378 |
|
| 2008 |
Bala M, Chin CN, Logan AT, Amin T, Marnett LJ, Boutaud O, Oates JA. Acetylation of prostaglandin H2 synthases by aspirin is inhibited by redox cycling of the peroxidase. Biochemical Pharmacology. 75: 1472-81. PMID 18242581 DOI: 10.1016/J.Bcp.2007.12.005 |
0.376 |
|
| 2008 |
Vila A, Tallman KA, Jacobs AT, Liebler DC, Porter NA, Marnett LJ. Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives. Chemical Research in Toxicology. 21: 432-44. PMID 18232660 DOI: 10.1021/Tx700347W |
0.521 |
|
| 2008 |
Szekely J, Rizzo CJ, Marnett LJ. Chemical properties of oxopropenyl adducts of purine and pyrimidine nucleosides and their reactivity toward amino acid cross-link formation. Journal of the American Chemical Society. 130: 2195-201. PMID 18225895 DOI: 10.1021/Ja074506U |
0.324 |
|
| 2007 |
Knutson CG, Wang H, Rizzo CJ, Marnett LJ. Metabolism and elimination of the endogenous DNA adduct, 3-(2-deoxy-β-D-erythropentofuranosyl)-pyrimido[1,2-α]purine-10(3H) -one, in the rat Journal of Biological Chemistry. 282: 36257-36264. PMID 17951255 DOI: 10.1074/Jbc.M706814200 |
0.312 |
|
| 2007 |
Druckova A, Mernaugh RL, Ham AJL, Marnett LJ. Identification of the protein targets of the reactive metabolite of teucrin A in vivo in the rat Chemical Research in Toxicology. 20: 1393-1408. PMID 17892266 DOI: 10.1021/Tx7001405 |
0.339 |
|
| 2007 |
Harman CA, Turman MV, Kozak KR, Marnett LJ, Smith WL, Garavito RM. Structural basis of enantioselective inhibition of cyclooxygenase-1 by S-alpha-substituted indomethacin ethanolamides. The Journal of Biological Chemistry. 282: 28096-105. PMID 17656360 DOI: 10.1074/Jbc.M701335200 |
0.771 |
|
| 2007 |
Vila A, Rosengarth A, Piomelli D, Cravatt B, Marnett LJ. Hydrolysis of prostaglandin glycerol esters by the endocannabinoid-hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase. Biochemistry. 46: 9578-85. PMID 17649977 DOI: 10.1021/Bi7005898 |
0.357 |
|
| 2007 |
Felts AS, Ji C, Stafford JB, Crews BC, Kingsley PJ, Rouzer CA, Washington MK, Subbaramaiah K, Siegel BS, Young SM, Dannenberg AJ, Marnett LJ. Desmethyl derivatives of indomethacin and sulindac as probes for cyclooxygenase-dependent biology. Acs Chemical Biology. 2: 479-83. PMID 17602619 DOI: 10.1021/Cb700077Z |
0.322 |
|
| 2007 |
Prusakiewicz JJ, Turman MV, Vila A, Ball HL, Al-Mestarihi AH, Di Marzo V, Marnett LJ. Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases. Archives of Biochemistry and Biophysics. 464: 260-8. PMID 17493578 DOI: 10.1016/J.Abb.2007.04.007 |
0.792 |
|
| 2007 |
Rouzer CA, Ivanova PT, Byrne MO, Brown HA, Marnett LJ. Lipid profiling reveals glycerophospholipid remodeling in zymosan-stimulated macrophages Biochemistry. 46: 6026-6042. PMID 17458939 DOI: 10.1021/Bi0621617 |
0.304 |
|
| 2007 |
Blobaum AL, Marnett LJ. Molecular determinants for the selective inhibition of cyclooxygenase-2 by lumiracoxib Journal of Biological Chemistry. 282: 16379-16390. PMID 17434872 DOI: 10.1074/Jbc.M609883200 |
0.34 |
|
| 2007 |
Trostchansky A, O'Donnell VB, Goodwin DC, Landino LM, Marnett LJ, Radi R, Rubbo H. Interactions between nitric oxide and peroxynitrite during prostaglandin endoperoxide H synthase-1 catalysis: A free radical mechanism of inactivation Free Radical Biology and Medicine. 42: 1029-1038. PMID 17349930 DOI: 10.1016/J.Freeradbiomed.2007.01.009 |
0.78 |
|
| 2007 |
Yu Y, Fan J, Hui Y, Rouzer CA, Marnett LJ, Klein-Szanto AJ, FitzGerald GA, Funk CD. Targeted cyclooxygenase gene (ptgs) exchange reveals discriminant isoform functionality. The Journal of Biological Chemistry. 282: 1498-506. PMID 17110378 DOI: 10.1074/Jbc.M609930200 |
0.322 |
|
| 2006 |
Rouzer CA, Ivanova PT, Byrne MO, Milne SB, Marnett LJ, Brown HA. Lipid profiling reveals arachidonate deficiency in RAW264.7 cells: Structural and functional implications Biochemistry. 45: 14795-14808. PMID 17144673 DOI: 10.1021/Bi061723J |
0.325 |
|
| 2006 |
Wang H, Kozekov ID, Kozekova A, Tamura PJ, Marnett LJ, Harris TM, Rizzo CJ. Site-specific synthesis of oligonucleotides containing malondialdehyde adducts of deoxyguanosine and deoxyadenosine via a postsynthetic modification strategy. Chemical Research in Toxicology. 19: 1467-74. PMID 17112234 DOI: 10.1021/Tx060137O |
0.329 |
|
| 2006 |
Druckova A, Marnett LJ. Characterization of the amino acid adducts of the enedial derivative of teucrin A Chemical Research in Toxicology. 19: 1330-1340. PMID 17040102 DOI: 10.1021/Tx060143K |
0.361 |
|
| 2006 |
Feng Z, Hu W, Marnett LJ, Tang Ms. Malondialdehyde, a major endogenous lipid peroxidation product, sensitizes human cells to UV- and BPDE-induced killing and mutagenesis through inhibition of nucleotide excision repair Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 601: 125-136. PMID 16872641 DOI: 10.1016/J.Mrfmmm.2006.06.003 |
0.362 |
|
| 2006 |
Rouzer CA, Tranguch S, Wang H, Zhang H, Dey SK, Marnett LJ. Zymosan-induced glycerylprostaglandin and prostaglandin synthesis in resident peritoneal macrophages: Roles of cyclo-oxygenase-1 and -2 Biochemical Journal. 399: 91-99. PMID 16787386 DOI: 10.1042/Bj20060615 |
0.31 |
|
| 2006 |
Otteneder MB, Knutson CG, Daniels JS, Hashim M, Crews BC, Remmel RP, Wang H, Rizzo C, Marnett LJ. In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG Proceedings of the National Academy of Sciences of the United States of America. 103: 6665-6669. PMID 16614064 DOI: 10.1073/Pnas.0602017103 |
0.349 |
|
| 2005 |
West JD, Marnett LJ. Alterations in gene expression induced by the lipid peroxidation product, 4-hydroxy-2-nonenal. Chemical Research in Toxicology. 18: 1642-53. PMID 16300372 DOI: 10.1021/Tx050211N |
0.339 |
|
| 2005 |
Kalgutkar AS, Crews BC, Saleh S, Prudhomme D, Marnett LJ. Indolyl esters and amides related to indomethacin are selective COX-2 inhibitors Bioorganic and Medicinal Chemistry. 13: 6810-6822. PMID 16169736 DOI: 10.1016/J.Bmc.2005.07.073 |
0.33 |
|
| 2005 |
Rouzer CA, Marnett LJ. Structural and functional differences between cyclooxygenases: Fatty acid oxygenases with a critical role in cell signaling Biochemical and Biophysical Research Communications. 338: 34-44. PMID 16126167 DOI: 10.1016/J.Bbrc.2005.07.198 |
0.377 |
|
| 2005 |
Rouzer CA, Marnett LJ. Glycerylprostaglandin synthesis by resident peritoneal macrophages in response to a zymosan stimulus. The Journal of Biological Chemistry. 280: 26690-700. PMID 15917246 DOI: 10.1074/Jbc.M501021200 |
0.316 |
|
| 2005 |
VanderVeen LA, Druckova A, Riggins JN, Sorrells JL, Guengerich FP, Marnett LJ. Differential DNA recognition and cleavage by EcoRI dependent on the dynamic equilibrium between the two forms of the malondialdehyde-deoxyguanosine adduct Biochemistry. 44: 5024-5033. PMID 15794640 DOI: 10.1021/Bi0472898 |
0.32 |
|
| 2005 |
Kadiiska MB, Gladen BC, Baird DD, Graham LB, Parker CE, Ames BN, Basu S, Fitzgerald GA, Lawson JA, Marnett LJ, Morrow JD, Murray DM, Plastaras J, Roberts LJ, Rokach J, et al. Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning. Free Radical Biology & Medicine. 38: 711-8. PMID 15721981 DOI: 10.1016/J.Freeradbiomed.2004.10.024 |
0.351 |
|
| 2005 |
Kadiiska MB, Gladen BC, Baird DD, Germolec D, Graham LB, Parker CE, Nyska A, Wachsman JT, Ames BN, Basu S, Brot N, Fitzgerald GA, Floyd RA, George M, Heinecke JW, ... ... Marnett LJ, et al. Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radical Biology & Medicine. 38: 698-710. PMID 15721980 DOI: 10.1016/J.Freeradbiomed.2004.09.017 |
0.313 |
|
| 2005 |
West JD, Ji C, Marnett LJ. Modulation of DNA fragmentation factor 40 nuclease activity by poly(ADP-ribose) polymerase-1. The Journal of Biological Chemistry. 280: 15141-7. PMID 15703174 DOI: 10.1074/Jbc.M413147200 |
0.306 |
|
| 2005 |
Hata AN, Lybrand TP, Marnett LJ, Breyer RM. Structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin D2 receptor CRTH2 Molecular Pharmacology. 67: 640-647. PMID 15563582 DOI: 10.1124/Mol.104.007971 |
0.31 |
|
| 2005 |
Clark SR, Anning PB, Coffey MJ, Roberts AG, Marnett LJ, O'Donnell VB. Depletion of iNOS-derived nitric oxide by prostaglandin H synthase-2 in inflammation-activated J774.2 macrophages through lipohydroperoxidase turnover. The Biochemical Journal. 385: 815-21. PMID 15461587 DOI: 10.1042/Bj20041353 |
0.316 |
|
| 2004 |
Prusakiewicz JJ, Felts AS, Mackenzie BS, Marnett LJ. Molecular basis of the time-dependent inhibition of cyclooxygenases by indomethacin. Biochemistry. 43: 15439-45. PMID 15581355 DOI: 10.1021/Bi048534Q |
0.3 |
|
| 2004 |
Riggins JN, Pratt DA, Voehler M, Daniels JS, Marnett LJ. Kinetics and mechanism of the general-acid-catalyzed ring-closure of the malondialdehyde-DNA adduct, N2-(3-oxo-1-propenyl)deoxyguanosine (N2OPdG-), to 3-(2'-Deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin- 10(3H)-one (M1dG). Journal of the American Chemical Society. 126: 10571-81. PMID 15327313 DOI: 10.1021/Ja040010Q |
0.582 |
|
| 2004 |
West JD, Ji C, Duncan ST, Amarnath V, Schneider C, Rizzo CJ, Brash AR, Marnett LJ. Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation. Chemical Research in Toxicology. 17: 453-62. PMID 15089087 DOI: 10.1021/Tx034248O |
0.337 |
|
| 2004 |
Wang H, Marnett LJ, Harris TM, Rizzo CJ. A novel synthesis of malondialdehyde adducts of deoxyguanosine, deoxyadenosine, and deoxycytidine. Chemical Research in Toxicology. 17: 144-9. PMID 14967001 DOI: 10.1021/Tx034174G |
0.35 |
|
| 2004 |
Kozak KR, Prusakiewicz JJ, Marnett LJ. Oxidative metabolism of endocannabinoids by COX-2. Current Pharmaceutical Design. 10: 659-67. PMID 14965328 DOI: 10.2174/1381612043453081 |
0.345 |
|
| 2004 |
Remmel RP, Crews BC, Kozak KR, Kalgutkar AS, Marnett LJ, Algutkar AS. Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 113-22. PMID 14709628 DOI: 10.1124/Dmd.32.1.113 |
0.318 |
|
| 2003 |
Rowlinson SW, Kiefer JR, Prusakiewicz JJ, Pawlitz JL, Kozak KR, Kalgutkar AS, Stallings WC, Kurumbail RG, Marnett LJ. A novel mechanism of cyclooxygenase-2 inhibition involving interactions with Ser-530 and Tyr-385. The Journal of Biological Chemistry. 278: 45763-9. PMID 12925531 DOI: 10.1074/Jbc.M305481200 |
0.329 |
|
| 2003 |
Kozak KR, Prusakiewicz JJ, Rowlinson SW, Prudhomme DR, Marnett LJ. Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid anandamide. Biochemistry. 42: 9041-9. PMID 12885237 DOI: 10.1021/Bi034471K |
0.348 |
|
| 2003 |
Rouzer CA, Marnett LJ. Mechanism of free radical oxygenation of polyunsaturated fatty acids by cyclooxygenases. Chemical Reviews. 103: 2239-304. PMID 12797830 DOI: 10.1021/Cr000068X |
0.306 |
|
| 2003 |
Niedernhofer LJ, Daniels JS, Rouzer CA, Greene RE, Marnett LJ. Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells. The Journal of Biological Chemistry. 278: 31426-33. PMID 12775726 DOI: 10.1074/Jbc.M212549200 |
0.321 |
|
| 2003 |
Marnett LJ, Riggins JN, West JD. Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein Journal of Clinical Investigation. 111: 583-593. PMID 12618510 DOI: 10.1172/Jci18022 |
0.321 |
|
| 2003 |
Aronoff DM, Boutaud O, Marnett LJ, Oates JA. Inhibition of prostaglandin H2 synthases by salicylate is dependent on the oxidative state of the enzymes. The Journal of Pharmacology and Experimental Therapeutics. 304: 589-95. PMID 12538810 DOI: 10.1124/Jpet.102.042853 |
0.355 |
|
| 2003 |
Marnett LJ. Oxy radicals, lipid peroxidation and DNA damage. Toxicology. 219-22. PMID 12505314 DOI: 10.1016/S0300-483X(02)00448-1 |
0.348 |
|
| 2003 |
Kalgutkar AS, Rowlinson SW, Crews BC, Marnett LJ. Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 12: 521-4. PMID 11844663 DOI: 10.1016/S0960-894X(01)00792-2 |
0.308 |
|
| 2002 |
Kozak KR, Crews BC, Morrow JD, Wang LH, Ma YH, Weinander R, Jakobsson PJ, Marnett LJ. Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. The Journal of Biological Chemistry. 277: 44877-85. PMID 12244105 DOI: 10.1074/Jbc.M206788200 |
0.336 |
|
| 2002 |
Prusakiewicz JJ, Kingsley PJ, Kozak KR, Marnett LJ. Selective oxygenation of N-arachidonylglycine by cyclooxygenase-2. Biochemical and Biophysical Research Communications. 296: 612-7. PMID 12176025 DOI: 10.1016/S0006-291X(02)00915-4 |
0.353 |
|
| 2002 |
Moody JS, Marnett LJ. Kinetics of inhibition of leukocyte 12-lipoxygenase by the isoform-specific inhibitor 4-(2-oxapentadeca-4-yne)phenylpropanoic acid. Biochemistry. 41: 10297-303. PMID 12162745 DOI: 10.1021/Bi020320Q |
0.352 |
|
| 2002 |
Kozak KR, Marnett LJ. Oxidative metabolism of endocannabinoids. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 66: 211-20. PMID 12052037 DOI: 10.1054/Plef.2001.0359 |
0.353 |
|
| 2002 |
Boutaud O, Aronoff DM, Richardson JH, Marnett LJ, Oates JA. Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases. Proceedings of the National Academy of Sciences of the United States of America. 99: 7130-5. PMID 12011469 DOI: 10.1073/Pnas.102588199 |
0.339 |
|
| 2002 |
Kozak KR, Gupta RA, Moody JS, Ji C, Boeglin WE, DuBois RN, Brash AR, Marnett LJ. 15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist. The Journal of Biological Chemistry. 277: 23278-86. PMID 11956198 DOI: 10.1074/Jbc.M201084200 |
0.333 |
|
| 2002 |
Sekhar KR, Spitz DR, Harris S, Nguyen TT, Meredith MJ, Holt JT, Gius D, Marnett LJ, Summar ML, Freeman ML, Guis D. Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase. Free Radical Biology & Medicine. 32: 650-62. PMID 11909699 DOI: 10.1016/S0891-5849(02)00755-4 |
0.32 |
|
| 2002 |
Kurumbail RG, Kiefer JR, Marnett LJ. Cyclooxygenase enzymes: catalysis and inhibition. Current Opinion in Structural Biology. 11: 752-60. PMID 11751058 DOI: 10.1016/S0959-440X(01)00277-9 |
0.349 |
|
| 2002 |
Schneider C, Boeglin WE, Prusakiewicz JJ, Rowlinson SW, Marnett LJ, Samel N, Brash AR. Control of prostaglandin stereochemistry at the 15-carbon by cyclooxygenases-1 and -2. A critical role for serine 530 and valine 349. The Journal of Biological Chemistry. 277: 478-85. PMID 11677234 DOI: 10.1074/Jbc.M107471200 |
0.345 |
|
| 2001 |
Boutaud O, Li J, Chaurand P, Brame CJ, Marnett LJ, Roberts LJ, Oates JA. Oxygenation of arachidonic acid by cyclooxygenases generates reactive intermediates that form adducts with proteins. Advances in Experimental Medicine and Biology. 500: 133-7. PMID 11764925 DOI: 10.1007/978-1-4615-0667-6_16 |
0.352 |
|
| 2001 |
Sharma RA, Gescher A, Plastaras JP, Leuratti C, Singh R, Gallacher-Horley B, Offord E, Marnett LJ, Steward WP, Plummer SM. Cyclooxygenase-2, malondialdehyde and pyrimidopurinone adducts of deoxyguanosine in human colon cells. Carcinogenesis. 22: 1557-60. PMID 11532880 DOI: 10.1093/Carcin/22.9.1557 |
0.309 |
|
| 2001 |
Riggins JN, Marnett LJ. Mutagenicity of the malondialdehyde oligomerization products 2-(3'-oxo-1'-propenyl)-malondialdehyde and 2,4-dihydroxymethylene-3-(2,2-dimethoxyethyl)glutaraldehyde in Salmonella. Mutation Research. 497: 153-7. PMID 11525918 DOI: 10.1016/S1383-5718(01)00253-4 |
0.302 |
|
| 2001 |
Kozak KR, Crews BC, Ray JL, Tai HH, Morrow JD, Marnett LJ. Metabolism of prostaglandin glycerol esters and prostaglandin ethanolamides in vitro and in vivo. The Journal of Biological Chemistry. 276: 36993-8. PMID 11447235 DOI: 10.1074/Jbc.M105854200 |
0.303 |
|
| 2001 |
Kozak KR, Prusakiewicz JJ, Rowlinson SW, Schneider C, Marnett LJ. Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid 2-arachidonylglycerol. The Journal of Biological Chemistry. 276: 30072-7. PMID 11402053 DOI: 10.1074/Jbc.M104467200 |
0.345 |
|
| 2001 |
Boutaud O, Brame CJ, Chaurand P, Li J, Rowlinson SW, Crews BC, Ji C, Marnett LJ, Caprioli RM, Roberts LJ, Oates JA. Characterization of the lysyl adducts of prostaglandin H-synthases that are derived from oxygenation of arachidonic acid. Biochemistry. 40: 6948-55. PMID 11389610 DOI: 10.1021/Bi002629K |
0.387 |
|
| 2001 |
Ji C, Kozak KR, Marnett LJ. IkappaB kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal. The Journal of Biological Chemistry. 276: 18223-8. PMID 11359792 DOI: 10.1074/Jbc.M101266200 |
0.312 |
|
| 2001 |
Moody JS, Kozak KR, Ji C, Marnett LJ. Selective oxygenation of the endocannabinoid 2-arachidonylglycerol by leukocyte-type 12-lipoxygenase. Biochemistry. 40: 861-6. PMID 11170406 DOI: 10.1021/Bi002303B |
0.312 |
|
| 2001 |
Plastaras JP, Riggins JN, Otteneder M, Marnett LJ. Reactivity and mutagenicity of endogenous DNA oxopropenylating agents: base propenals, malondialdehyde, and N(epsilon)-oxopropenyllysine. Chemical Research in Toxicology. 13: 1235-42. PMID 11123964 DOI: 10.1021/Tx0001631 |
0.316 |
|
| 2000 |
Kalgutkar AS, Marnett AB, Crews BC, Remmel RP, Marnett LJ. Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. Journal of Medicinal Chemistry. 43: 2860-70. PMID 10956194 DOI: 10.1021/Jm000004E |
0.337 |
|
| 2000 |
Kozak KR, Rowlinson SW, Marnett LJ. Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2. The Journal of Biological Chemistry. 275: 33744-9. PMID 10931854 DOI: 10.1074/Jbc.M007088200 |
0.347 |
|
| 2000 |
Lanzo CA, Sutin J, Rowlinson S, Talley J, Marnett LJ. Fluorescence quenching analysis of the association and dissociation of a diarylheterocycle to cyclooxygenase-1 and cyclooxygenase-2: dynamic basis of cyclooxygenase-2 selectivity. Biochemistry. 39: 6228-34. PMID 10821698 DOI: 10.1021/Bi992761O |
0.309 |
|
| 2000 |
Goodwin DC, Rowlinson SW, Marnett LJ. Substitution of tyrosine for the proximal histidine ligand to the heme of prostaglandin endoperoxide synthase 2: implications for the mechanism of cyclooxygenase activation and catalysis. Biochemistry. 39: 5422-32. PMID 10820014 DOI: 10.1021/Bi992752F |
0.315 |
|
| 2000 |
Kiefer JR, Pawlitz JL, Moreland KT, Stegeman RA, Hood WF, Gierse JK, Stevens AM, Goodwin DC, Rowlinson SW, Marnett LJ, Stallings WC, Kurumbail RG. Structural insights into the stereochemistry of the cyclooxygenase reaction. Nature. 405: 97-101. PMID 10811226 DOI: 10.1038/35011103 |
0.34 |
|
| 2000 |
Marnett LJ, Wright TL, Crews BC, Tannenbaum SR, Morrow JD. Regulation of prostaglandin biosynthesis by nitric oxide is revealed by targeted deletion of inducible nitric-oxide synthase Journal of Biological Chemistry. 275: 13427-13430. PMID 10788454 DOI: 10.1074/Jbc.275.18.13427 |
0.303 |
|
| 2000 |
Rowlinson SW, Crews BC, Goodwin DC, Schneider C, Gierse JK, Marnett LJ. Spatial requirements for 15-(R)-hydroxy-5Z,8Z,11Z, 13E-eicosatetraenoic acid synthesis within the cyclooxygenase active site of murine COX-2. Why acetylated COX-1 does not synthesize 15-(R)-hete. The Journal of Biological Chemistry. 275: 6586-91. PMID 10692466 DOI: 10.1074/Jbc.275.9.6586 |
0.337 |
|
| 2000 |
Kalgutkar AS, Crews BC, Rowlinson SW, Garner C, Marnett LJ. Discovery of a new class of selective cyclooxygenase-2 (COX-2) inhibitor that covalently modifies the isozyme. Advances in Experimental Medicine and Biology. 469: 139-43. PMID 10667322 DOI: 10.1007/978-1-4615-4793-8_21 |
0.345 |
|
| 2000 |
Kalgutkar AS, Crews BC, Rowlinson SW, Marnett AB, Kozak KR, Remmel RP, Marnett LJ. Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 97: 925-30. PMID 10639181 DOI: 10.1073/Pnas.97.2.925 |
0.338 |
|
| 1999 |
Richards KM, Moody JS, Marnett LJ. Mechanism of inhibition of porcine leukocyte 12-lipoxygenase by the isoform-specific inhibitor 4-(2-oxapentadeca-4-yne)phenylpropanoic acid Biochemistry. 38: 16529-16538. PMID 10600114 DOI: 10.1021/Bi991336S |
0.377 |
|
| 1999 |
Rowlinson SW, Crews BC, Lanzo CA, Marnett LJ. The binding of arachidonic acid in the cyclooxygenase active site of mouse prostaglandin endoperoxide synthase-2 (COX-2). A putative L-shaped binding conformation utilizing the top channel region. The Journal of Biological Chemistry. 274: 23305-10. PMID 10438506 DOI: 10.1074/Jbc.274.33.23305 |
0.33 |
|
| 1999 |
Marnett LJ, Rowlinson SW, Goodwin DC, Kalgutkar AS, Lanzo CA. Arachidonic acid oxygenation by COX-1 and COX-2. Mechanisms of catalysis and inhibition. The Journal of Biological Chemistry. 274: 22903-6. PMID 10438452 DOI: 10.1074/Jbc.274.33.22903 |
0.32 |
|
| 1999 |
Goodwin DC, Landino LM, Marnett LJ. Effects of nitric oxide and nitric oxide-derived species on prostaglandin endoperoxide synthase and prostaglandin biosynthesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 1121-36. PMID 10385604 DOI: 10.1096/Fasebj.13.10.1121 |
0.33 |
|
| 1998 |
Kadlubar FF, Anderson KE, Häussermann S, Lang NP, Barone GW, Thompson PA, MacLeod SL, Chou MW, Mikhailova M, Plastaras J, Marnett LJ, Nair J, Velic I, Bartsch H. Comparison of DNA adduct levels associated with oxidative stress in human pancreas. Mutation Research. 405: 125-33. PMID 9748537 DOI: 10.1016/S0027-5107(98)00129-8 |
0.329 |
|
| 1998 |
Dedon PC, Plastaras JP, Rouzer CA, Marnett LJ. Indirect mutagenesis by oxidative DNA damage: Formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal Proceedings of the National Academy of Sciences of the United States of America. 95: 11113-11116. PMID 9736698 DOI: 10.1073/Pnas.95.19.11113 |
0.314 |
|
| 1998 |
Kalgutkar AS, Crews BC, Rowlinson SW, Garner C, Seibert K, Marnett LJ. Aspirin-like molecules that covalently inactivate cyclooxygenase-2. Science (New York, N.Y.). 280: 1268-70. PMID 9596581 DOI: 10.1126/Science.280.5367.1268 |
0.313 |
|
| 1998 |
Smith CJ, Morrow JD, Roberts LJ, Marnett LJ. Induction of prostaglandin endoperoxide synthase-1 (COX-1) in a human promonocytic cell line by treatment with the differentiating agent TPA. Advances in Experimental Medicine and Biology. 99-106. PMID 9547543 DOI: 10.1007/978-1-4615-5325-0_14 |
0.314 |
|
| 1998 |
Goodwin DC, Gunther MR, Hsi LC, Crews BC, Eling TE, Mason RP, Marnett LJ. Nitric oxide trapping of tyrosyl radicals generated during prostaglandin endoperoxide synthase turnover. Detection of the radical derivative of tyrosine 385. The Journal of Biological Chemistry. 273: 8903-9. PMID 9535872 DOI: 10.1074/Jbc.273.15.8903 |
0.331 |
|
| 1997 |
Kalgutkar AS, Crews BC, Marnett LJ. Inactivation of prostaglandin endoperoxide synthase (PGHS) by N-(substituted)maleimides. Advances in Experimental Medicine and Biology. 407: 79-85. PMID 9321935 DOI: 10.1007/978-1-4899-1813-0_12 |
0.369 |
|
| 1997 |
Landino LM, Crews BC, Gierse JK, Hauser SD, Marnett LJ. Mutational analysis of the role of the distal histidine and glutamine residues of prostaglandin-endoperoxide synthase-2 in peroxidase catalysis, hydroperoxide reduction, and cyclooxygenase activation. The Journal of Biological Chemistry. 272: 21565-74. PMID 9261177 DOI: 10.1074/Jbc.272.34.21565 |
0.329 |
|
| 1997 |
Gunther MR, Hsi LC, Curtis JF, Gierse JK, Marnett LJ, Eling TE, Mason RP. Nitric oxide trapping of the tyrosyl radical of prostaglandin H synthase-2 leads to tyrosine iminoxyl radical and nitrotyrosine formation. The Journal of Biological Chemistry. 272: 17086-90. PMID 9202025 DOI: 10.1074/Jbc.272.27.17086 |
0.327 |
|
| 1997 |
Richards KM, Marnett LJ. Leukocyte 12-lipoxygenase: Expression, purification, and investigation of the role of methionine residues in turnover-dependent inactivation and 5,8,11,14-eicosatetraynoic acid inhibition Biochemistry. 36: 6692-6699. PMID 9184149 DOI: 10.1021/Bi963051A |
0.336 |
|
| 1997 |
Sevilla CL, Mahle NH, Eliezer N, Uzieblo A, O'Hara SM, Nokubo M, Miller R, Rouzer CA, Marnett LJ. Development of monoclonal antibodies to the malondialdehyde- deoxyguanosine adduct, pyrimidopurinone Chemical Research in Toxicology. 10: 172-180. PMID 9049428 DOI: 10.1021/Tx960120D |
0.317 |
|
| 1997 |
Smith CJ, Marnett LJ. Effects of cysteine-to-serine mutations on structural and functional properties of prostaglandin endoperoxide synthase. Archives of Biochemistry and Biophysics. 335: 342-50. PMID 8914931 DOI: 10.1006/Abbi.1996.0515 |
0.308 |
|
| 1996 |
Landino LM, Crews BC, Timmons MD, Morrow JD, Marnett LJ. Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 15069-74. PMID 8986765 DOI: 10.1073/Pnas.93.26.15069 |
0.349 |
|
| 1996 |
Gorins G, Kuhnert L, Johnson CR, Marnett LJ. (Carboxyalkyl)benzyl propargyl ethers as selective inhibitors of leukocyte-type 12-lipoxygenases Journal of Medicinal Chemistry. 39: 4871-4878. PMID 8960545 DOI: 10.1021/Jm9606047 |
0.313 |
|
| 1996 |
Kalgutkar AS, Crews BC, Marnett LJ. Design, synthesis, and biochemical evaluation of N-substituted maleimides as inhibitors of prostaglandin endoperoxide synthases. Journal of Medicinal Chemistry. 39: 1692-703. PMID 8648609 DOI: 10.1021/Jm950872P |
0.331 |
|
| 1996 |
Chaudhary AK, Reddy GR, Blair IA, Marnett LJ. Characterization of an N6-oxopropenyl-2′-deoxyadenosine adduct in malondialdehyde-modified DNA using liquid chromatography/electrospray ionization tandem mass spectrometry Carcinogenesis. 17: 1167-1170. PMID 8640930 DOI: 10.1093/Carcin/17.5.1167 |
0.304 |
|
| 1996 |
Landino LM, Marnett LJ. Mechanism of hydroperoxide reduction by mangano-prostaglandin endoperoxide synthase. Biochemistry. 35: 2637-43. PMID 8611568 DOI: 10.1021/Bi952546H |
0.348 |
|
| 1994 |
Kalgutkar AS, Marnett LJ. Rapid inactivation of prostaglandin endoperoxide synthases by N-(carboxyalkyl)maleimides. Biochemistry. 33: 8625-8. PMID 8038151 DOI: 10.1021/Bi00195A002 |
0.306 |
|
| 1994 |
Reddy RG, Yoshimoto T, Yamamoto S, Funk CD, Marnett LJ. Expression of porcine leukocyte 12-lipoxygenase in a baculovirus/insect cell system and its characterization. Archives of Biochemistry and Biophysics. 312: 219-26. PMID 8031130 DOI: 10.1006/Abbi.1994.1302 |
0.348 |
|
| 1994 |
Beckman JK, Bagheri F, Ji C, Blair IA, Marnett LJ. Phospholipid peroxidation in tumor promoter-exposed mouse skin. Carcinogenesis. 15: 2937-44. PMID 8001259 DOI: 10.1093/Carcin/15.12.2937 |
0.353 |
|
| 1994 |
Reddy RG, Yoshimoto T, Yamamoto S, Marnett LJ. Expression, purification, and characterization of porcine leukocyte 12-lipoxygenase produced in the methylotrophic yeast, Pichia pastoris. Biochemical and Biophysical Research Communications. 205: 381-8. PMID 7999053 DOI: 10.1006/Bbrc.1994.2676 |
0.302 |
|
| 1993 |
Smith CJ, Morrow JD, Roberts LJ, Marnett LJ. Differentiation of monocytoid THP-1 cells with phorbol ester induces expression of prostaglandin endoperoxide synthase-1 (COX-1). Biochemical and Biophysical Research Communications. 192: 787-93. PMID 8484784 DOI: 10.1006/Bbrc.1993.1483 |
0.324 |
|
| 1993 |
Wells I, Marnett LJ. Inactivation of prostaglandin endoperoxide synthase by acylating derivatives of indomethacin. Biochemistry. 32: 2710-6. PMID 8448128 DOI: 10.1021/Bi00061A032 |
0.359 |
|
| 1993 |
Wilcox AL, Marnett LJ. Polyunsaturated fatty acid alkoxyl radicals exist as carbon-centered epoxyallylic radicals: a key step in hydroperoxide-amplified lipid peroxidation. Chemical Research in Toxicology. 6: 413-6. PMID 8374035 DOI: 10.1021/Tx00034A003 |
0.334 |
|
| 1993 |
Marnett L. Commentary. Frontiers in Molecular Toxicology Chemical Research in Toxicology. 6: 739-740. DOI: 10.1021/Tx00036A600 |
0.383 |
|
| 1992 |
Basu AK, O'Hara SM, Valladier P, Stone K, Mols O, Marnett LJ. Identification of adducts formed by reaction of guanine nucleosides with malondialdehyde and structurally related aldehydes. Chemical Research in Toxicology. 1: 53-9. PMID 2979712 DOI: 10.1021/Tx00001A010 |
0.772 |
|
| 1992 |
O'Gara CY, Maddipati KR, Marnett LJ. A sensitive electrochemical method for quantitative hydroperoxide determination. Chemical Research in Toxicology. 2: 295-300. PMID 2519821 DOI: 10.1021/Tx00011A005 |
0.32 |
|
| 1992 |
Stone K, Uzieblo A, Marnett LJ. Studies of the reaction of malondialdehyde with cytosine nucleosides. Chemical Research in Toxicology. 3: 467-72. PMID 2133098 DOI: 10.1021/Tx00017A013 |
0.78 |
|
| 1992 |
Pal I, Odenwaller R, Marnett LJ. 7-Oxabicycloheptylprostanoic acids: Potent, time-dependent cyclooxygenase inhibitors that induce a conformational change in the prostaglandin endoperoxide synthase protein [1] Journal of Medicinal Chemistry. 35: 2340-2342. PMID 1613757 DOI: 10.1021/Jm00090A026 |
0.317 |
|
| 1992 |
Reddy AP, Pruess-Schwartz D, Marnett LJ. Separation of (+)-syn- and (-)-anti-benzo[a]pyrene dihydrodiol epoxide-DNA adducts in 32P-postlabeling analysis. Chemical Research in Toxicology. 5: 19-25. PMID 1581531 DOI: 10.1021/Tx00025A005 |
0.306 |
|
| 1992 |
Wells I, Marnett LJ. Acetylation of prostaglandin endoperoxide synthase by N-acetylimidazole: Comparison to acetylation by aspirin Biochemistry. 31: 9520-9525. PMID 1390734 DOI: 10.1021/Bi00155A002 |
0.351 |
|
| 1992 |
Benamira M, Marnett LJ. The lipid peroxidation product 4-hydroxynonenal is a potent inducer of the SOS response. Mutation Research. 293: 1-10. PMID 1383804 DOI: 10.1016/0921-8777(92)90002-K |
0.309 |
|
| 1991 |
Samokyszyn VM, Marnett LJ. Inhibition of liver microsomal lipid peroxidation by 13-cis-retinoic acid. Free Radical Biology & Medicine. 8: 491-6. PMID 2253899 DOI: 10.1016/0891-5849(90)90063-O |
0.345 |
|
| 1991 |
Marnett LJ. Prostaglandin synthase-mediated metabolism of carcinogens and a potential role for peroxyl radicals as reactive intermediates. Environmental Health Perspectives. 88: 5-12. PMID 2125560 DOI: 10.1289/Ehp.90885 |
0.382 |
|
| 1991 |
Samokyszyn VM, Marnett LJ. Inhibition of microsomal lipid peroxidation by 13-cis-retinoic acid. Methods in Enzymology. 190: 281-8. PMID 2087179 DOI: 10.1016/0076-6879(90)90033-W |
0.312 |
|
| 1991 |
Marnett LJ. Peroxyl free radicals: biological reactive intermediates produced during lipid oxidation. Advances in Experimental Medicine and Biology. 283: 65-70. PMID 2069034 DOI: 10.1007/978-1-4684-5877-0_6 |
0.347 |
|
| 1991 |
Smith WL, Marnett LJ. Prostaglandin endoperoxide synthase: structure and catalysis Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 1083: 1-17. PMID 1903304 DOI: 10.1016/0005-2760(91)90119-3 |
0.311 |
|
| 1990 |
Odenwaller R, Chen YN, Marnett LJ. Preparation and proteolytic cleavage of apoprostaglandin endoperoxide synthase. Methods in Enzymology. 187: 479-85. PMID 2122187 DOI: 10.1016/0076-6879(90)87054-7 |
0.316 |
|
| 1990 |
Laudicina DC, Marnett LJ. Enhancement of hydroperoxide-dependent lipid peroxidation in rat liver microsomes by ascorbic acid. Archives of Biochemistry and Biophysics. 278: 73-80. PMID 2108607 DOI: 10.1016/0003-9861(90)90233-O |
0.337 |
|
| 1990 |
Stone K, Ksebati MB, Marnett LJ. Investigation of the adducts formed by reaction of malondialdehyde with adenosine [Erratum to document cited in CA112(11):93606w] Chemical Research in Toxicology. 3: 169-169. DOI: 10.1021/Tx00014A014 |
0.751 |
|
| 1989 |
Labeque R, Marnett LJ. Reaction of hematin with allylic fatty acid hydroperoxides: identification of products and implications for pathways of hydroperoxide-dependent epoxidation of 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene. Biochemistry. 27: 7060-70. PMID 3196701 DOI: 10.1021/Bi00418A059 |
0.346 |
|
| 1989 |
Padbury G, Sligar SG, Labeque R, Marnett LJ. Ferric bleomycin catalyzed reduction of 10-hydroperoxy-8,12-octadecadienoic acid: evidence for homolytic O-O bond scission. Biochemistry. 27: 7846-52. PMID 2462909 DOI: 10.1021/Bi00420A039 |
0.316 |
|
| 1989 |
Chen YP, Marnett LJ. Heme prosthetic group required for acetylation of prostaglandin H synthase by aspirin The Faseb Journal. 3: 2294-2297. DOI: 10.1096/Fasebj.3.11.2506093 |
0.323 |
|
| 1988 |
O'Brian CA, Ward NE, Weinstein IB, Bull AW, Marnett LJ. Activation of rat brain protein kinase C by lipid oxidation products. Biochemical and Biophysical Research Communications. 155: 1374-80. PMID 3178815 DOI: 10.1016/S0006-291X(88)81293-2 |
0.351 |
|
| 1988 |
Capdevila J, Gil L, Orellana M, Marnett LJ, Mason JI, Yadagiri P, Falck JR. Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism. Archives of Biochemistry and Biophysics. 261: 257-63. PMID 3128168 DOI: 10.1016/0003-9861(88)90340-2 |
0.327 |
|
| 1986 |
Weller PE, Markey CM, Marnett LJ. Enzymatic reduction of 5-phenyl-4-pentenyl-hydroperoxide: detection of peroxidases and identification of peroxidase reducing substrates. Archives of Biochemistry and Biophysics. 243: 633-43. PMID 4083906 DOI: 10.1016/0003-9861(85)90541-7 |
0.307 |
|
| 1986 |
Dix TA, Buck JR, Marnett LJ. Hydroperoxide-dependent epoxidation of 3,4-dihydroxy-3,4-dihydrobenzo[a]anthracene by ram seminal vesicle microsomes and by hematin. Biochemical and Biophysical Research Communications. 140: 181-7. PMID 3096315 DOI: 10.1016/0006-291X(86)91074-0 |
0.649 |
|
| 1986 |
Eling T, Curtis J, Battista J, Marnett LJ. Oxidation of (+)-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene by mouse keratinocytes: evidence for peroxyl radical- and monoxygenase-dependent metabolism. Carcinogenesis. 7: 1957-63. PMID 2430728 DOI: 10.1093/Carcin/7.12.1957 |
0.347 |
|
| 1985 |
Battista JR, Marnett LJ. Prostaglandin H synthase-dependent epoxidation of aflatoxin B1. Carcinogenesis. 6: 1227-9. PMID 3926338 DOI: 10.1093/Carcin/6.8.1227 |
0.314 |
|
| 1984 |
Dix TA, Marnett LJ. Detection of the metabolism of polycyclic aromatic hydrocarbon derivatives to ultimate carcinogens during lipid peroxidation. Methods in Enzymology. 105: 347-52. PMID 6539415 DOI: 10.1016/S0076-6879(84)05046-1 |
0.65 |
|
| 1984 |
Samokyszyn VM, Sloane BF, Honn KV, Marnett LJ. Cooxidation of 13-cis-retinoic acid by prostaglandin H synthase Biochemical and Biophysical Research Communications. 124: 430-436. PMID 6437401 DOI: 10.1016/0006-291X(84)91571-7 |
0.329 |
|
| 1984 |
Siedlik PH, Marnett LJ. Oxidizing radical generation by prostaglandin H synthase. Methods in Enzymology. 105: 412-6. PMID 6427550 DOI: 10.1016/S0076-6879(84)05057-6 |
0.357 |
|
| 1983 |
Morton KC, King CM, Vaught JB, Wang CY, Lee MS, Marnett LJ. Prostaglandin H synthase-mediated reaction of carcinogenic arylamines with tRNA and homopolyribonucleotides. Biochemical and Biophysical Research Communications. 111: 96-103. PMID 6403016 DOI: 10.1016/S0006-291X(83)80122-3 |
0.332 |
|
| 1983 |
Basu AK, Marnett LJ. Unequivocal demonstration that malondialdehyde is a mutagen. Carcinogenesis. 4: 331-3. PMID 6339098 DOI: 10.1093/Carcin/4.3.331 |
0.344 |
|
| 1983 |
Dix TA, Marnett LJ. Metabolism of polycyclic aromatic hydrocarbon derivatives to ultimate carcinogens during lipid peroxidation. Science (New York, N.Y.). 221: 77-9. PMID 6304879 DOI: 10.1126/Science.6304879 |
0.643 |
|
| 1983 |
Dix TA, Marnett LJ. Hematin-catalyzed rearrangement of hydroperoxylinoleic acid to epoxy alcohols via an oxygen rebound Journal of the American Chemical Society. 105: 7001-7002. DOI: 10.1021/Ja00361A063 |
0.61 |
|
| 1982 |
Honn KV, Bockman RS, Marnett LJ. Prostaglandins and cancer: a review of tumor initiation through tumor metastasis. Prostaglandins. 21: 833-64. PMID 6280245 DOI: 10.1016/0090-6980(81)90240-9 |
0.333 |
|
| 1982 |
DIX TA, MARNETT LJ. ChemInform Abstract: FREE RADICAL EPOXIDATION OF 7,8-DIHYDROXY-7,8-DIHYDROBENZO(A)PYRENE BY HEMATIN AND POLYUNSATURATED FATTY ACID HYDROPEROXIDES Chemischer Informationsdienst. 13. DOI: 10.1002/CHIN.198207129 |
0.597 |
|
| 1981 |
Marnett LJ. Polycyclic aromatic hydrocarbon oxidation during prostaglandin biosynthesis. Life Sciences. 29: 531-46. PMID 6268915 DOI: 10.1016/0024-3205(81)90431-8 |
0.365 |
|
| 1981 |
Dix TA, Marnett LJ. Free radical epoxidation of 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene by hematin and polyunsaturated fatty acid hydroperoxides Journal of the American Chemical Society. 103: 6744-6746. DOI: 10.1021/Ja00412A037 |
0.631 |
|
| 1980 |
Porter NA, Wolf RA, Pagels WR, Marnett LJ. A test for the intermediacy of 11-hydroperoxyeicosa-5,8,12,14-tetraenoic acid [11-HPETE] in prostaglandin biosynthesis. Biochemical and Biophysical Research Communications. 92: 349-55. PMID 6766722 DOI: 10.1016/0006-291X(80)90340-X |
0.47 |
|
| 1979 |
Marnett LJ, Johnson JT, Bienkowski MJ. Arachidonic acid-dependent metabolism of 7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene by ram seminal vesicles. Febs Letters. 106: 13-6. PMID 499485 DOI: 10.1016/0014-5793(79)80684-5 |
0.31 |
|
| 1979 |
Marnett LJ, Reed GA. Peroxidatic oxidation of benzo[a]pyrene and prostaglandin biosynthesis. Biochemistry. 18: 2923-9. PMID 111706 DOI: 10.1021/Bi00581A001 |
0.352 |
|
| 1979 |
Egan RW, Gale PH, Beveridge GC, Phillips GB, Marnett LJ. Radical scavenging as the mechanism for stimulation of prostaglandin cyclooxygenase and depression of inflammation by lipoic acid and sodium iodide. Prostaglandins. 16: 861-9. PMID 107544 DOI: 10.1016/0090-6980(78)90102-8 |
0.335 |
|
| 1978 |
Marnett LJ, Reed GA, Johnson JT. Prostaglandin synthetase dependent benzo(a)pyrene oxidation: products of the oxication and inhibition of their formation by antioxidants. Biochemical and Biophysical Research Communications. 79: 569-76. PMID 412501 DOI: 10.1016/0006-291X(77)90195-4 |
0.339 |
|
| 1978 |
Marnett LJ, Reed GA, Dennison DJ. Prostaglandin synthetase dependent activation of 7,8-dihydro-7,8-dihydroxy-geno (a) pyrene to mutagenic derivativies. Biochemical and Biophysical Research Communications. 82: 210-6. PMID 96834 DOI: 10.1016/0006-291X(78)90597-1 |
0.354 |
|
| 1977 |
Marnett LJ, Wilcox CL. Stimulation of prostaglandin biosynthesis by lipoic acid. Biochimica Et Biophysica Acta. 487: 222-30. PMID 403953 DOI: 10.1016/0005-2760(77)90058-3 |
0.364 |
|
| 1977 |
Marnett LJ, Bienkowski MJ. Nonenzymatic reduction of prostaglandin H by lipoic acid. Biochemistry. 16: 4303-7. PMID 332228 DOI: 10.1021/Bi00638A027 |
0.304 |
|
| 1975 |
Marnett LJ, Wlodawer P, Samuelsson B. Light emission during the action of prostaglandin synthetase. Biochemical and Biophysical Research Communications. 60: 1286-94. PMID 4424375 DOI: 10.1016/0006-291X(74)90337-4 |
0.422 |
|
| 1973 |
Porter NA, Marnett LJ. Photolysis of unsymmetric azo compounds. cis Azo compound intermediates Journal of the American Chemical Society. 95: 4361-4367. DOI: 10.1021/Ja00794A036 |
0.439 |
|
| 1973 |
Marnett L, Smith P, Porter N. An EPR investigation of hydrazyl radicals formed in azo compound protolyses Tetrahedron Letters. 14: 1081-1084. DOI: 10.1016/S0040-4039(01)95909-X |
0.385 |
|
| 1973 |
PORTER NA, MARNETT LJ. ChemInform Abstract: PHOTOLYSIS OF UNSYMMETRIC AZO COMPOUNDS, CIS AZO COMPOUND INTERMEDIATES Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/CHIN.197335147 |
0.365 |
|
| 1973 |
MARNETT LJ, SMITH P, PORTER NA. ChemInform Abstract: EPR-UNTERSUCHUNG VON HYDRAZYL-RADIKALEN AUS DER PHOTOLYSE VON AZOVERBINDUNGEN (I)-(III) Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197326185 |
0.331 |
|
| 1971 |
Porter NA, Landis ME, Marnett LJ. Photolysis of unsymmetric azo compounds Journal of the American Chemical Society. 93: 795-796. DOI: 10.1021/Ja00732A051 |
0.432 |
|
| 1971 |
PORTER NA, LANDIS ME, MARNETT LJ. ChemInform Abstract: PHOTOLYSE UNSYMMETRISCHER AZOVERBINDUNGEN Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197117180 |
0.418 |
|
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