Year |
Citation |
Score |
2023 |
Sampognaro PJ, Arya S, Knudsen GM, Gunderson EL, Sandoval-Perez A, Hodul M, Bowles K, Craik CS, Jacobson MP, Kao AW. Correction: Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases. Molecular Neurodegeneration. 18: 34. PMID 37254128 DOI: 10.1186/s13024-023-00629-0 |
0.728 |
|
2023 |
Sampognaro PJ, Arya S, Knudsen GM, Gunderson EL, Sandoval-Perez A, Hodul M, Bowles K, Craik CS, Jacobson MP, Kao AW. Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases. Molecular Neurodegeneration. 18: 29. PMID 37131250 DOI: 10.1186/s13024-023-00621-8 |
0.734 |
|
2022 |
Hwang JL, Perloff OS, Gaus SE, Benitez C, Alquezar C, Cosme CQ, Nana AL, Vatsavayai SC, Ramos EM, Geschwind DH, Miller BL, Kao AW, Seeley WW. Tuberous sclerosis complex is associated with a novel human tauopathy. Acta Neuropathologica. PMID 36469115 DOI: 10.1007/s00401-022-02521-5 |
0.754 |
|
2022 |
Argouarch AR, Schultz N, Yang AC, Jang Y, Garcia K, Cosme CG, Corrales CI, Nana AL, Karydas AM, Spina S, Grinberg LT, Miller B, Wyss-Coray T, Abyzov A, Goodarzi H, ... ... Kao AW, et al. Postmortem Human Dura Mater Cells Exhibit Phenotypic, Transcriptomic and Genetic Abnormalities that Impact their Use for Disease Modeling. Stem Cell Reviews and Reports. PMID 35809166 DOI: 10.1007/s12015-022-10416-x |
0.704 |
|
2022 |
Chin MY, Ang KH, Davies J, Alquezar C, Garda VG, Rooney B, Leng K, Kampmann M, Arkin MR, Kao AW. Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model. Acs Chemical Neuroscience. 13: 1505-1516. PMID 35522480 DOI: 10.1021/acschemneuro.1c00804 |
0.664 |
|
2021 |
Alquezar C, Schoch KM, Geier EG, Ramos EM, Scrivo A, Li KH, Argouarch AR, Mlynarski EE, Dombroski B, DeTure M, Dickson DW, Yokoyama JS, Cuervo AM, Burlingame AL, Schellenberg GD, ... ... Kao AW, et al. TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy. Science Advances. 7: eabg3897. PMID 34739309 DOI: 10.1126/sciadv.abg3897 |
0.708 |
|
2021 |
Mohan S, Sampognaro PJ, Argouarch AR, Maynard JC, Welch M, Patwardhan A, Courtney EC, Zhang J, Mason A, Li KH, Huang EJ, Seeley WW, Miller BL, Burlingame A, Jacobson MP, ... Kao AW, et al. Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration. Molecular Neurodegeneration. 16: 51. PMID 34344440 DOI: 10.1186/s13024-021-00472-1 |
0.55 |
|
2021 |
Chin MY, Patwardhan AR, Ang KH, Wang AL, Alquezar C, Welch M, Nguyen PT, Grabe M, Molofsky AV, Arkin MR, Kao AW. Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH. Acs Sensors. PMID 34102054 DOI: 10.1021/acssensors.0c02318 |
0.657 |
|
2020 |
Alquezar C, Arya S, Kao AW. Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation. Frontiers in Neurology. 11: 595532. PMID 33488497 DOI: 10.3389/fneur.2020.595532 |
0.765 |
|
2020 |
Alquezar C, Felix JB, McCandlish E, Buckley BT, Caparros-Lefebvre D, Karch CM, Golbe LI, Kao AW. Heavy metals contaminating the environment of a progressive supranuclear palsy cluster induce tau accumulation and cell death in cultured neurons. Scientific Reports. 10: 569. PMID 31953414 DOI: 10.1038/S41598-019-56930-W |
0.714 |
|
2019 |
Liu AJ, Staffaroni AM, Rojas-Martinez JC, Olney NT, Alquezar-Burillo C, Ljubenkov PA, La Joie R, Fong JC, Taylor J, Karydas A, Ramos EM, Coppola G, Boxer AL, Rabinovici GD, Miller BL, ... Kao AW, et al. Association of Cognitive and Behavioral Features Between Adults With Tuberous Sclerosis and Frontotemporal Dementia. Jama Neurology. PMID 31860018 DOI: 10.1001/Jamaneurol.2019.4284 |
0.539 |
|
2019 |
Karch CM, Kao AW, Karydas A, Onanuga K, Martinez R, Argouarch A, Wang C, Huang C, Sohn PD, Bowles KR, Spina S, Silva MC, Marsh JA, Hsu S, Pugh DA, et al. A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies. Stem Cell Reports. PMID 31631020 DOI: 10.1016/J.Stemcr.2019.09.006 |
0.618 |
|
2019 |
Butler VJ, Gao F, Corrales CI, Cortopassi WA, Caballero B, Vohra M, Ashrafi K, Cuervo AM, Jacobson MP, Coppola G, Kao AW. Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response. Plos Genetics. 15: e1008295. PMID 31398187 DOI: 10.1371/Journal.Pgen.1008295 |
0.351 |
|
2019 |
Butler VJ, Cortopassi WA, Argouarch AR, Ivry SL, Craik CS, Jacobson MP, Kao AW. Progranulin Stimulates the in vitro Maturation of pro-Cathepsin D at Acidic pH. Journal of Molecular Biology. PMID 30690031 DOI: 10.1016/J.Jmb.2019.01.027 |
0.347 |
|
2018 |
Butler VJ, Salazar DA, Soriano-Castell D, Alves-Ferreira M, Dennissen FJA, Vohra M, Oses-Prieto JA, Li KH, Wang AL, Jing B, Li B, Groisman A, Gutierrez E, Mooney S, Burlingame AL, ... ... Kao AW, et al. Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport. Human Molecular Genetics. PMID 30590647 DOI: 10.1093/Hmg/Ddy442 |
0.397 |
|
2018 |
Li Y, Barkovich MJ, Karch CM, Nillo RM, Fan CC, Broce IJ, Tan CH, Cuneo D, Hess CP, Dillon WP, Glenn OA, Glastonbury CM, Olney N, Yokoyama JS, Bonham LW, ... ... Kao A, et al. Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex. Scientific Reports. 8: 13373. PMID 30190613 DOI: 10.1038/S41598-018-31075-4 |
0.41 |
|
2018 |
Hsu TY, Butler VJ, Kao AW. The Use of Caenorhabditis elegans to Study Progranulin in the Regulation of Programmed Cell Death and Stress Response. Methods in Molecular Biology (Clifton, N.J.). 1806: 193-206. PMID 29956278 DOI: 10.1007/978-1-4939-8559-3_14 |
0.302 |
|
2017 |
Perry DC, Brown JA, Possin KL, Datta S, Trujillo A, Radke A, Karydas A, Kornak J, Sias AC, Rabinovici GD, Gorno-Tempini ML, Boxer AL, De May M, Rankin KP, Sturm VE, ... ... Kao AW, et al. Clinicopathological correlations in behavioural variant frontotemporal dementia. Brain : a Journal of Neurology. PMID 29053860 DOI: 10.1093/Brain/Awx254 |
0.658 |
|
2017 |
Olney NT, Alquezar C, Ramos EM, Nana AL, Fong JC, Karydas AM, Taylor JB, Stephens ML, Argouarch AR, Van Berlo VA, Dokuru DR, Sherr EH, Jicha GA, Dillon WP, Desikan RS, ... ... Kao AW, et al. Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia. Acta Neuropathologica. PMID 28828560 DOI: 10.1007/S00401-017-1764-0 |
0.72 |
|
2017 |
Kao AW, McKay A, Singh PP, Brunet A, Huang EJ. Progranulin, lysosomal regulation and neurodegenerative disease. Nature Reviews. Neuroscience. PMID 28435163 DOI: 10.1038/Nrn.2017.36 |
0.351 |
|
2016 |
Bettcher BM, Fitch R, Wynn MJ, Lalli MA, Elofson J, Jastrzab L, Mitic L, Miller ZA, Rabinovici GD, Miller BL, Kao AW, Kosik KS, Kramer JH. MCP-1 and eotaxin-1 selectively and negatively associate with memory in MCI and Alzheimer's disease dementia phenotypes. Alzheimer's & Dementia (Amsterdam, Netherlands). 3: 91-7. PMID 27453930 DOI: 10.1016/J.Dadm.2016.05.004 |
0.553 |
|
2015 |
Lalli MA, Bettcher BM, Arcila ML, Garcia G, Guzman C, Madrigal L, Ramirez L, Acosta-Uribe J, Baena A, Wojta KJ, Coppola G, Fitch R, de Both MD, Huentelman MJ, Reiman EM, ... ... Kao AW, et al. Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer's disease. Molecular Psychiatry. PMID 26324103 DOI: 10.1038/Mp.2015.131 |
0.321 |
|
2015 |
Salazar DA, Butler VJ, Argouarch AR, Hsu TY, Mason A, Nakamura A, McCurdy H, Cox D, Ng R, Pan G, Seeley WW, Miller BL, Kao AW. The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 9315-28. PMID 26109656 DOI: 10.1523/Jneurosci.4808-14.2015 |
0.603 |
|
2013 |
Judy ME, Nakamura A, Huang A, Grant H, McCurdy H, Weiberth KF, Gao F, Coppola G, Kenyon C, Kao AW. A shift to organismal stress resistance in programmed cell death mutants. Plos Genetics. 9: e1003714. PMID 24068943 DOI: 10.1371/Journal.Pgen.1003714 |
0.707 |
|
2013 |
Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, et al. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 189-98. PMID 23062850 DOI: 10.1016/J.Jalz.2012.03.003 |
0.589 |
|
2013 |
Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, et al. Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 176-88. PMID 23043900 DOI: 10.1016/J.Jalz.2012.03.002 |
0.603 |
|
2011 |
Kao AW, Eisenhut RJ, Martens LH, Nakamura A, Huang A, Bagley JA, Zhou P, de Luis A, Neukomm LJ, Cabello J, Farese RV, Kenyon C. A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 4441-6. PMID 21368173 DOI: 10.1073/Pnas.1100650108 |
0.544 |
|
2009 |
Kao AW, Racine CA, Quitania LC, Kramer JH, Christine CW, Miller BL. Cognitive and neuropsychiatric profile of the synucleinopathies: Parkinson disease, dementia with Lewy bodies, and multiple system atrophy. Alzheimer Disease and Associated Disorders. 23: 365-70. PMID 19935145 DOI: 10.1097/Wad.0B013E3181B5065D |
0.372 |
|
2009 |
Roberson ED, Kao AW. Animal models of dementia The Behavioral Neurology of Dementia. 131-141. DOI: 10.1017/CBO9780511581410.010 |
0.445 |
|
2000 |
Kao AW, Yang C, Pessin JE. Functional comparison of the role of dynamin 2 splice variants on GLUT-4 endocytosis in 3T3L1 adipocytes. American Journal of Physiology. Endocrinology and Metabolism. 278: E825-31. PMID 10780938 DOI: 10.1152/Ajpendo.2000.278.5.E825 |
0.653 |
|
1999 |
Summers SA, Kao AW, Kohn AD, Backus GS, Roth RA, Pessin JE, Birnbaum MJ. The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism. The Journal of Biological Chemistry. 274: 17934-40. PMID 10364240 DOI: 10.1074/Jbc.274.25.17934 |
0.517 |
|
1999 |
Kao AW, Noda Y, Johnson JH, Pessin JE, Saltiel AR. Aldolase mediates the association of F-actin with the insulin-responsive glucose transporter GLUT4. The Journal of Biological Chemistry. 274: 17742-7. PMID 10364216 DOI: 10.1074/Jbc.274.25.17742 |
0.52 |
|
1999 |
Duan D, Li Q, Kao AW, Yue Y, Pessin JE, Engelhardt JF. Dynamin Is Required for Recombinant Adeno-Associated Virus Type 2 Infection Journal of Virology. 73: 10371-10376. DOI: 10.1128/Jvi.73.12.10371-10376.1999 |
0.514 |
|
1998 |
Kao AW, Ceresa BP, Santeler SR, Pessin JE. Expression of a dominant interfering dynamin mutant in 3T3L1 adipocytes inhibits GLUT4 endocytosis without affecting insulin signaling. The Journal of Biological Chemistry. 273: 25450-7. PMID 9738014 DOI: 10.1074/Jbc.273.39.25450 |
0.705 |
|
1998 |
Ceresa BP, Kao AW, Santeler SR, Pessin JE. Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways. Molecular and Cellular Biology. 18: 3862-70. PMID 9632770 DOI: 10.1128/Mcb.18.7.3862 |
0.698 |
|
1997 |
Okada S, Kao AW, Ceresa BP, Blaikie P, Margolis B, Pessin JE. The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway. The Journal of Biological Chemistry. 272: 28042-9. PMID 9346957 DOI: 10.1074/Jbc.272.44.28042 |
0.714 |
|
1997 |
Kao AW, Waters SB, Okada S, Pessin JE. Insulin stimulates the phosphorylation of the 66- and 52-kilodalton Shc isoforms by distinct pathways. Endocrinology. 138: 2474-80. PMID 9165038 DOI: 10.1210/Endo.138.6.5203 |
0.547 |
|
1996 |
Waters SB, Chen D, Kao AW, Okada S, Holt KH, Pessin JE. Insulin and epidermal growth factor receptors regulate distinct pools of Grb2-SOS in the control of Ras activation. The Journal of Biological Chemistry. 271: 18224-30. PMID 8663461 DOI: 10.1074/Jbc.271.30.18224 |
0.528 |
|
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