| Year |
Citation |
Score |
| 2023 |
Chen D, Ermine K, Wang YJ, Chen X, Lu X, Wang P, Beer-Stolz D, Yu J, Zhang L. PUMA/RIP3 mediates chemotherapy response via necroptosis and local immune activation in colorectal cancer. Molecular Cancer Therapeutics. PMID 37992761 DOI: 10.1158/1535-7163.MCT-23-0162 |
0.318 |
|
| 2023 |
Tong J, Tan X, Hao S, Ermine K, Lu X, Liu Z, Jha A, Yu J, Zhang L. Inhibition of multiple CDKs potentiates colon cancer chemotherapy via p73-mediated DR5 induction. Oncogene. PMID 36721000 DOI: 10.1038/s41388-023-02598-6 |
0.373 |
|
| 2022 |
Hao S, Tong J, Jha A, Risnik D, Lizardo D, Lu X, Goel A, Opresko PL, Yu J, Zhang L. Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer. Proceedings of the National Academy of Sciences of the United States of America. 119: e2211775119. PMID 36508676 DOI: 10.1073/pnas.2211775119 |
0.405 |
|
| 2022 |
Kuang C, Tong J, Ermine K, Cai M, Dai F, Hao S, Giles F, Huang Y, Yu J, Zhang L. Dual inhibition of BET and HAT/p300 suppresses colorectal cancer via DR5- and p53/PUMA-mediated cell death. Frontiers in Oncology. 12: 1018775. PMID 36313707 DOI: 10.3389/fonc.2022.1018775 |
0.301 |
|
| 2022 |
Ruan H, Leibowitz BJ, Peng Y, Shen L, Chen L, Kuang C, Schoen RE, Lu X, Zhang L, Yu J. Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer. Molecular Biomedicine. 3: 10. PMID 35307764 DOI: 10.1186/s43556-022-00070-7 |
0.343 |
|
| 2022 |
Tong J, Tan X, Song X, Gao M, Risnik D, Hao S, Ermine K, Wang P, Li H, Huang Y, Yu J, Zhang L. CDK4/6 inhibition suppresses p73 phosphorylation and activates DR5 to potentiate chemotherapy and immune checkpoint blockade. Cancer Research. PMID 35149588 DOI: 10.1158/0008-5472.CAN-21-3062 |
0.35 |
|
| 2021 |
Tong J, Tan X, Risnik D, Gao M, Song X, Ermine K, Shen L, Wang S, Yu J, Zhang L. BET protein degradation triggers DR5-mediated immunogenic cell death to suppress colorectal cancer and potentiate immune checkpoint blockade. Oncogene. 40: 6566-6578. PMID 34615996 DOI: 10.1038/s41388-021-02041-8 |
0.328 |
|
| 2020 |
Song X, Shen L, Tong J, Kuang C, Zeng S, Schoen RE, Yu J, Pei H, Zhang L. Mcl-1 inhibition overcomes intrinsic and acquired regorafenib resistance in colorectal cancer. Theranostics. 10: 8098-8110. PMID 32724460 DOI: 10.7150/Thno.45363 |
0.371 |
|
| 2020 |
Ruan H, Leibowitz BJ, Zhang L, Yu J. Immunogenic cell death in colon cancer prevention and therapy. Molecular Carcinogenesis. PMID 32215970 DOI: 10.1002/Mc.23183 |
0.405 |
|
| 2020 |
Dang Y, Zhang Y, Xu L, Zhou X, Gu Y, Yu J, Jin S, Ji H, Shu Y, Zhang G, Cui S, Sun J. PUMA-mediated epithelial cell apoptosis promotes Helicobacter pylori infection-mediated gastritis. Cell Death & Disease. 11: 139. PMID 32080167 DOI: 10.1038/S41419-020-2339-X |
0.331 |
|
| 2020 |
Zhang X, Fisher R, Hou W, Shields D, Epperly MW, Wang H, Wei L, Leibowitz BJ, Yu J, Alexander LM, VAN Pijkeren JP, Watkins S, Wipf P, Greenberger JS. Second-generation Probiotics Producing IL-22 Increase Survival of Mice After Total Body Irradiation. In Vivo (Athens, Greece). 34: 39-50. PMID 31882461 DOI: 10.21873/Invivo.11743 |
0.314 |
|
| 2019 |
Sun J, Wang C, Zhang Y, Xu L, Fang W, Zhu Y, Zheng Y, Chen X, Xie X, Hu X, Hu W, Zheng J, Li P, Yu J, Mei Z, et al. Genomic signatures reveal DNA damage response deficiency in colorectal cancer brain metastases. Nature Communications. 10: 3190. PMID 31320627 DOI: 10.1038/S41467-019-10987-3 |
0.33 |
|
| 2019 |
Yu C, Liu Q, Chen C, Yu J, Wang J. Landscape perspectives of tumor, EMT, and development. Physical Biology. PMID 31067516 DOI: 10.1088/1478-3975/Ab2029 |
0.381 |
|
| 2019 |
Tan X, Tong J, Wang YJ, Fletcher R, Schoen RE, Yu J, Shen L, Zhang L. BET inhibitors potentiate chemotherapy and killing of SPOP-mutant colon cancer cells via induction of DR5. Cancer Research. PMID 30674532 DOI: 10.1158/0008-5472.Can-18-3223 |
0.453 |
|
| 2018 |
Chen D, Ni HM, Wang L, Ma X, Yu J, Ding WX, Zhang L. PUMA induction mediates acetaminophen-induced necrosis and liver injury. Hepatology (Baltimore, Md.). PMID 30552702 DOI: 10.1002/Hep.30422 |
0.321 |
|
| 2018 |
He X, Yao MW, Zhu M, Liang DL, Guo W, Yang Y, Zhao RS, Ren TT, Ao X, Wang W, Zeng CY, Liang HP, Jiang DP, Yu J, Xu X. Metformin induces apoptosis in mesenchymal stromal cells and dampens their therapeutic efficacy in infarcted myocardium. Stem Cell Research & Therapy. 9: 306. PMID 30409193 DOI: 10.1186/S13287-018-1057-0 |
0.302 |
|
| 2018 |
Wang YJ, Fletcher R, Yu J, Zhang L. Immunogenic effects of chemotherapy-induced tumor cell death. Genes & Diseases. 5: 194-203. PMID 30320184 DOI: 10.1016/J.Gendis.2018.05.003 |
0.386 |
|
| 2018 |
Lee YS, Lee DH, Jeong SY, Park SH, Oh SC, Park YS, Yu J, Choudry HA, Bartlett DL, Lee YJ. Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5. Journal of Cellular Biochemistry. PMID 30160785 DOI: 10.1002/Jcb.27456 |
0.444 |
|
| 2018 |
Tong J, Zheng X, Tan X, Fletcher R, Nikolovska-Coleska Z, Yu J, Zhang L. Mcl-1 phosphorylation without degradation mediates sensitivity to HDAC inhibitors by liberating BH3-only proteins. Cancer Research. PMID 29895675 DOI: 10.1158/0008-5472.Can-18-0399 |
0.439 |
|
| 2018 |
Knickelbein K, Tong J, Chen D, Wang YJ, Misale S, Bardelli A, Yu J, Zhang L. Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer. Oncogene. PMID 29755130 DOI: 10.1038/S41388-018-0289-X |
0.365 |
|
| 2018 |
Chen D, Tong J, Yang L, Wei L, Stolz DB, Yu J, Zhang J, Zhang L. PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581256 DOI: 10.1073/Pnas.1717190115 |
0.339 |
|
| 2018 |
Leibowitz BJ, Yang L, Wei L, Buchanan ME, Rachid M, Parise RA, Beumer JH, Eiseman JL, Schoen RE, Zhang L, Yu J. Targeting p53-dependent stem cell loss for intestinal chemoprotection. Science Translational Medicine. 10. PMID 29437148 DOI: 10.1126/Scitranslmed.Aam7610 |
0.437 |
|
| 2018 |
Fletcher R, Wang YJ, Schoen RE, Finn OJ, Yu J, Zhang L. Colorectal cancer prevention: Immune modulation taking the stage. Biochimica Et Biophysica Acta. PMID 29391185 DOI: 10.1016/J.Bbcan.2017.12.002 |
0.326 |
|
| 2018 |
Kuboki Y, Guerra C, Beleva V, Huang W, Yu J, Chianchiano P, Hosoda W, Zheng L, Shao X, Thompson E, Waters K, Poling J, He J, Weiss M, Wolfgang C, et al. AB113. P087. Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions Annals of Pancreatic Cancer. 1: AB113-AB113. DOI: 10.21037/APC.2018.AB113 |
0.7 |
|
| 2018 |
Felsenstein M, Noe M, Masica D, Hosada W, Chianchiano P, Guerra C, Lionheart G, Brosens L, Pea A, Yu J, Gemenetzis G, Groot V, Makary M, He J, Weiss M, et al. AB077. P049. Genetic relationship of pancreatic ductal adenocarcinoma and co-occurring IPMN Annals of Pancreatic Cancer. 1: AB077-AB077. DOI: 10.21037/apc.2018.ab077 |
0.668 |
|
| 2018 |
Sun J, Wang C, Gu Y, Yu J, Hu Z, Gu Y. Genomic landscapes of brain metastasis patients of colorectal cancer to reveal clinical potential of individualized therapies. Journal of Clinical Oncology. 36: 674-674. DOI: 10.1200/Jco.2018.36.4_Suppl.674 |
0.304 |
|
| 2018 |
Knickelbein K, Tong J, Chen D, Wang Y, Misale S, Bardelli A, Yu J, Zhang L. Abstract 2861: PUMA induction by p73 mediates response and resistance of colorectal cancer to anti-EGFR antibody therapy Cancer Research. 78: 2861-2861. DOI: 10.1158/1538-7445.Am2018-2861 |
0.416 |
|
| 2018 |
Fletcher RE, Leibowitz B, Wang Y, Concha-Benavente F, Ferris R, Schoen R, Yu J, Zhang L. Abstract 267: Nonsteroidal anti-inflammatory drugs induce ER stress- and BID-dependent immunogenic cell death to suppress colorectal tumorigenesis Cancer Research. 78: 267-267. DOI: 10.1158/1538-7445.Am2018-267 |
0.399 |
|
| 2018 |
Ruan H, Li X, Leibowitz B, Tong J, Lu X, Sonenberg N, Xu X, Zhang L, Yu J. Abstract 2417: eIF4E phosphorylation licenses Myc-driven metabolic and stress reprogramming Cancer Research. 78: 2417-2417. DOI: 10.1158/1538-7445.Am2018-2417 |
0.432 |
|
| 2018 |
Kump KJ, Tong J, Mady AS, Miao L, Li S, Sun D, Yu J, Zhang L, Nikolovska-Coleska Z. Abstract 1970: Novel Mcl-1 inhibitor effectively restores in vivo regorafenib sensitivity in resistant colorectal cancer Cancer Research. 78: 1970-1970. DOI: 10.1158/1538-7445.Am2018-1970 |
0.462 |
|
| 2017 |
Zhang J, Song N, Zang D, Yu J, Li J, Di W, Guo R, Zhao W, Wang H. c-Myc promotes tumor proliferation and anti‑apoptosis by repressing p21 in rhabdomyosarcomas. Molecular Medicine Reports. PMID 28765944 DOI: 10.3892/mmr.2017.7101 |
0.319 |
|
| 2017 |
Tong J, Tan S, Nikolovska-Coleska Z, Yu J, Zou F, Zhang L. FBW7-dependent Mcl-1 degradation mediates the anticancer effect of Hsp90 inhibitors. Molecular Cancer Therapeutics. PMID 28619760 DOI: 10.1158/1535-7163.Mct-17-0032 |
0.389 |
|
| 2017 |
Zhong JT, Yu J, Wang HJ, Shi Y, Zhao TS, He BX, Qiao B, Feng ZW. Effects of endoplasmic reticulum stress on the autophagy, apoptosis, and chemotherapy resistance of human breast cancer cells by regulating the PI3K/AKT/mTOR signaling pathway. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 39: 1010428317697562. PMID 28459209 DOI: 10.1177/1010428317697562 |
0.313 |
|
| 2017 |
Tong J, Wang P, Tan S, Chen D, Nikolovska-Coleska Z, Zou F, Yu J, Zhang L. Mcl-1 degradation is required for targeted therapeutics to eradicate colon cancer cells. Cancer Research. PMID 28202514 DOI: 10.1158/0008-5472.Can-16-3242 |
0.429 |
|
| 2017 |
Vendetti FP, Leibowitz BJ, Barnes J, Schamus S, Kiesel BF, Abberbock S, Conrads T, Clump DA, Cadogan E, O'Connor MJ, Yu J, Beumer JH, Bakkenist CJ. Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation. Scientific Reports. 7: 41892. PMID 28145510 DOI: 10.1038/Srep41892 |
0.372 |
|
| 2017 |
Tong J, Tan S, Zou F, Yu J, Zhang L. Abstract 3143:FBW7mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation Cancer Research. 77: 3143-3143. DOI: 10.1158/1538-7445.Am2017-3143 |
0.334 |
|
| 2017 |
Wang Y, Chen D, Tong J, Yu J, Bardelli A, Zhang L. Abstract 1692:KRAS-mediated therapeutic resistance abrogates immunogenic cell death in colorectal cancer cells Immunology. 77: 1692-1692. DOI: 10.1158/1538-7445.Am2017-1692 |
0.422 |
|
| 2017 |
Fletcher RE, Zhang L, Leibowitz B, Yu J. Abstract 1256: Non-steroidal anti-inflammatory drugs induce ER stress and have an immunomodulatory role in the suppression of colorectal tumorigenesis Cancer Research. 77: 1256-1256. DOI: 10.1158/1538-7445.Am2017-1256 |
0.428 |
|
| 2016 |
Li X, Li M, Ruan H, Qiu W, Xu X, Zhang L, Yu J. Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress. Oncotarget. PMID 28030835 DOI: 10.18632/Oncotarget.14063 |
0.412 |
|
| 2016 |
Tong J, Tan S, Zou F, Yu J, Zhang L. FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation. Oncogene. PMID 27399335 DOI: 10.1038/Onc.2016.247 |
0.39 |
|
| 2016 |
He K, Chen D, Ruan H, Li X, Tong J, Xu X, Zhang L, Yu J. BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells. Oncotarget. PMID 27351224 DOI: 10.18632/Oncotarget.10277 |
0.407 |
|
| 2016 |
Wang Y, Wang X, Flores ER, Yu J, Chang S. Dysfunctional telomeres induce p53-dependent and independent apoptosis to compromise cellular proliferation and inhibit tumor formation. Aging Cell. PMID 27113195 DOI: 10.1111/Acel.12476 |
0.407 |
|
| 2016 |
Chen D, Yu J, Zhang L. Necroptosis: an alternative cell death program defending against cancer. Biochimica Et Biophysica Acta. PMID 26968619 DOI: 10.1016/J.Bbcan.2016.03.003 |
0.396 |
|
| 2015 |
Uttam S, Pham HV, LaFace J, Leibowitz B, Yu J, Brand RE, Hartman DJ, Liu Y. Early prediction of cancer progression by depth-resolved nanoscale maps of nuclear architecture from unstained tissue specimens. Cancer Research. PMID 26383164 DOI: 10.1158/0008-5472.Can-15-1274 |
0.35 |
|
| 2015 |
Chen X, Song X, Yue W, Chen D, Yu J, Yao Z, Zhang L. Fibulin-5 inhibits Wnt/β-catenin signaling in lung cancer. Oncotarget. 6: 15022-34. PMID 25909283 DOI: 10.18632/Oncotarget.3609 |
0.347 |
|
| 2015 |
Brown MF, Leibowitz BJ, Chen D, He K, Zou F, Sobol RW, Beer-Stolz D, Zhang L, Yu J. Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis. Cell Death & Disease. 6: e1729. PMID 25906152 DOI: 10.1038/Cddis.2015.104 |
0.448 |
|
| 2015 |
He K, Zheng X, Li M, Zhang L, Yu J. mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation. Oncogene. PMID 25867072 DOI: 10.1038/Onc.2015.79 |
0.455 |
|
| 2015 |
Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Scientific Reports. 5: 8566. PMID 25858503 DOI: 10.1038/Srep08566 |
0.386 |
|
| 2015 |
He K, Zheng X, Li M, Zhang L, Yu J. Abstract LB-040: mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction upon 4E-BP1 dephosphorylation Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-040 |
0.468 |
|
| 2015 |
Chen D, Wei L, Yu J, Zhang L. Abstract 667: Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis Cancer Research. 75: 667-667. DOI: 10.1158/1538-7445.Am2015-667 |
0.471 |
|
| 2015 |
Tong J, Yu J, Zhang L. Abstract 2932: Role of death receptor 5 (DR5) in apoptosis induced by anticancer agents in colon cancer cells Cancer Research. 75: 2932-2932. DOI: 10.1158/1538-7445.Am2015-2932 |
0.436 |
|
| 2015 |
Sun J, Knickelbein K, He K, Chen D, Yu J, Zhang L. Abstract 2577: Aurora kinase inhibitors require PUMA to induce apoptosis and preferentially kill KRAS-mutant colon cancer cells Cancer Research. 75: 2577-2577. DOI: 10.1158/1538-7445.Am2015-2577 |
0.452 |
|
| 2014 |
Leibowitz B, Qiu W, Buchanan ME, Zou F, Vernon P, Moyer MP, Yin XM, Schoen RE, Yu J, Zhang L. BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs. Proceedings of the National Academy of Sciences of the United States of America. 111: 16520-5. PMID 25368155 DOI: 10.1073/Pnas.1415178111 |
0.443 |
|
| 2014 |
Chen D, Ming L, Zou F, Peng Y, Van Houten B, Yu J, Zhang L. TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity. Oncotarget. 5: 8107-22. PMID 25237903 DOI: 10.18632/Oncotarget.2440 |
0.402 |
|
| 2014 |
Chen D, Wei L, Yu J, Zhang L. Regorafenib inhibits colorectal tumor growth through PUMA-mediated apoptosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3472-84. PMID 24763611 DOI: 10.1158/1078-0432.Ccr-13-2944 |
0.43 |
|
| 2014 |
Sun J, Knickelbein K, He K, Chen D, Dudgeon C, Shu Y, Yu J, Zhang L. Aurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells. Molecular Cancer Therapeutics. 13: 1298-308. PMID 24563542 DOI: 10.1158/1535-7163.Mct-13-0846 |
0.435 |
|
| 2014 |
Chen X, Meng J, Yue W, Yu J, Yang J, Yao Z, Zhang L. Fibulin-3 suppresses Wnt/β-catenin signaling and lung cancer invasion. Carcinogenesis. 35: 1707-16. PMID 24480807 DOI: 10.1093/Carcin/Bgu023 |
0.317 |
|
| 2013 |
Zhang L, Yu J. Role of Apoptosis in Colon Cancer Biology, Therapy, and Prevention Current Colorectal Cancer Reports. 9: 331-340. PMID 24273467 DOI: 10.1007/S11888-013-0188-Z |
0.479 |
|
| 2013 |
He K, Zheng X, Zhang L, Yu J. Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax. Molecular Cancer Therapeutics. 12: 2559-68. PMID 23966620 DOI: 10.1158/1535-7163.Mct-13-0284 |
0.478 |
|
| 2013 |
Magness ST, Puthoff BJ, Crissey MA, Dunn J, Henning SJ, Houchen C, Kaddis JS, Kuo CJ, Li L, Lynch J, Martin MG, May R, Niland JC, Olack B, Qian D, ... ... Yu J, et al. A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G542-51. PMID 23928185 DOI: 10.1152/Ajpgi.00481.2012 |
0.309 |
|
| 2013 |
Qiu W, Wang X, Buchanan M, He K, Sharma R, Zhang L, Wang Q, Yu J. ADAR1 is essential for intestinal homeostasis and stem cell maintenance. Cell Death & Disease. 4: e599. PMID 23598411 DOI: 10.1038/Cddis.2013.125 |
0.345 |
|
| 2013 |
Zheng X, He K, Zhang L, Yu J. Crizotinib Induces PUMA-Dependent Apoptosis in Colon Cancer Cells Molecular Cancer Therapeutics. 12: 777-786. PMID 23427294 DOI: 10.1158/1535-7163.Mct-12-1146 |
0.524 |
|
| 2013 |
Spender LC, Carter MJ, O'Brien DI, Clark LJ, Yu J, Michalak EM, Happo L, Cragg MS, Inman GJ. Transforming growth factor-β directly induces p53-up-regulated modulator of apoptosis (PUMA) during the rapid induction of apoptosis in myc-driven B-cell lymphomas. The Journal of Biological Chemistry. 288: 5198-209. PMID 23243310 DOI: 10.1074/Jbc.M112.410274 |
0.353 |
|
| 2013 |
Qiu W, Liu H, Sebastini A, Sun Q, Wang H, Zhang L, Yu J. An apoptosis-independent role of SMAC in tumor suppression Oncogene. 32: 2380-2389. PMID 22751125 DOI: 10.1038/Onc.2012.265 |
0.439 |
|
| 2013 |
Yu J. Intestinal stem cell injury and protection during cancer therapy Translational Cancer Research. 2: 384-396. DOI: 10.21037/1380 |
0.357 |
|
| 2013 |
Sun J, He K, Yu J, Zhang L. Abstract LB-97: Aurora kinase inhibition suppresses colon cancer cell growth through NF-κb-mediated PUMA induction. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-97 |
0.45 |
|
| 2013 |
Leibowitz BJ, Li M, Wei L, Zhang L, Yu J. Abstract LB-44: A novel PUMA inhibitor protects against chemotherapy-induced intestinal injury without compromising tumor response. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-44 |
0.422 |
|
| 2013 |
Chen D, Ming L, Zou F, Yu J, Zhang L. Abstract 777: TAp73 depletion unleashes p53-mediated apoptotic response to lethal DNA damage. Cancer Research. 73: 777-777. DOI: 10.1158/1538-7445.Am2013-777 |
0.391 |
|
| 2013 |
Leibowitz B, Moyer MP, Yu J, Zhang L. Abstract B01: Nonsteroidal anti-inflammatory drugs selectively kill colon cancer cells through a synthetic lethal interaction Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-B01 |
0.466 |
|
| 2012 |
Sun J, Sun Q, Brown MF, Dudgeon C, Chandler J, Xu X, Shu Y, Zhang L, Yu J. The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA. Plos One. 7: e43158. PMID 22912816 DOI: 10.1371/Journal.Pone.0043158 |
0.468 |
|
| 2012 |
Bista RK, Uttam S, Hartman DJ, Qiu W, Yu J, Zhang L, Brand RE, Liu Y. Investigation of nuclear nano-morphology marker as a biomarker for cancer risk assessment using a mouse model. Journal of Biomedical Optics. 17: 066014. PMID 22734770 DOI: 10.1117/1.Jbo.17.6.066014 |
0.345 |
|
| 2012 |
Roberts NJ, Jiao Y, Yu J, Kopelovich L, Petersen GM, Bondy ML, Gallinger S, Schwartz AG, Syngal S, Cote ML, Axilbund J, Schulick R, Ali SZ, Eshleman JR, Velculescu VE, et al. ATM mutations in patients with hereditary pancreatic cancer Cancer Discovery. 2: 41-46. PMID 22585167 DOI: 10.1158/2159-8290.Cd-11-0194 |
0.708 |
|
| 2012 |
Dudgeon C, Peng R, Wang P, Sebastiani A, Yu J, Zhang L. Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth Oncogene. 31: 4848-4858. PMID 22286758 DOI: 10.1038/Onc.2011.644 |
0.307 |
|
| 2012 |
Kanda M, Matthaei H, Wu J, Hong SM, Yu J, Borges M, Hruban RH, Maitra A, Kinzler K, Vogelstein B, Goggins M. Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia Gastroenterology. 142: 730-733.e9. PMID 22226782 DOI: 10.1053/J.Gastro.2011.12.042 |
0.398 |
|
| 2012 |
Zheng X, He K, Sun J, Sun Q, Brown MF, Zhang L, Yu J. Abstract 932: Selective requirement of BH3-only proteins for apoptosis induced by targeted therapies in colon cancer cells and xenografts Cancer Research. 72: 932-932. DOI: 10.1158/1538-7445.Am2012-932 |
0.477 |
|
| 2012 |
Sun J, Sun Q, Brown MF, Dudgeon C, Chandler J, Zhang L, Yu J. Abstract 860: The multi-targeted kinase inhibitor Sunitinib induces apoptosis in colon cancer cells via PUMA Cancer Research. 72: 860-860. DOI: 10.1158/1538-7445.Am2012-860 |
0.507 |
|
| 2012 |
Dudgeon C, Buchanan ME, Peng R, Wang P, Sebastiani A, Yu J, Zhang L. Abstract 4650: Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth Cancer Research. 72: 4650-4650. DOI: 10.1158/1538-7445.Am2012-4650 |
0.432 |
|
| 2012 |
Bista RK, Uttam S, Hartman DJ, Qiu W, Yu J, Zhang L, Brand R, Liu Y. Su1904 Investigation of Nuclear Nano-Morphology Markers as a Novel Biomarker for Cancer Risk Assessment Using a Mouse Model Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)62043-5 |
0.304 |
|
| 2011 |
Qiu W, Wang X, Leibowitz B, Yang W, Zhang L, Yu J. PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice Hepatology. 54: 1249-1258. PMID 21725994 DOI: 10.1002/Hep.24516 |
0.418 |
|
| 2011 |
Dirisina R, Katzman RB, Goretsky T, Managlia E, Mittal N, Williams DB, Qiu W, Yu J, Chandel NS, Zhang L, Barrett TA. p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis. Gastroenterology. 141: 1036-45. PMID 21699775 DOI: 10.1053/J.Gastro.2011.05.032 |
0.46 |
|
| 2011 |
Xu Y, Zhou L, Huang J, Liu F, Yu J, Zhan Q, Zhang L, Zhao X. Role of Smac in determining the chemotherapeutic response of esophageal squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5412-22. PMID 21676925 DOI: 10.1158/1078-0432.Ccr-11-0426 |
0.341 |
|
| 2011 |
Li H, Wang P, Yu J, Zhang L. Cleaving Beclin 1 to suppress autophagy in chemotherapy-induced apoptosis Autophagy. 7: 1239-1241. PMID 21610315 DOI: 10.4161/Auto.7.10.16490 |
0.436 |
|
| 2011 |
Qiu W, Wu B, Wang X, Buchanan ME, Regueiro MD, Hartman DJ, Schoen RE, Yu J, Zhang L. PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice. The Journal of Clinical Investigation. 121: 1722-32. PMID 21490394 DOI: 10.1172/Jci42917 |
0.42 |
|
| 2011 |
Leibowitz BJ, Qiu W, Liu H, Cheng T, Zhang L, Yu J. Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21 Molecular Cancer Research. 9: 616-625. PMID 21450905 DOI: 10.1158/1541-7786.Mcr-11-0052 |
0.417 |
|
| 2011 |
Li H, Wang P, Sun Q, Ding WX, Yin XM, Sobol RW, Stolz DB, Yu J, Zhang L. Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1. Cancer Research. 71: 3625-34. PMID 21444671 DOI: 10.1158/0008-5472.Can-10-4475 |
0.445 |
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| 2011 |
Mustata G, Li M, Zevola N, Bakan A, Zhang L, Epperly M, Greenberger JS, Yu J, Bahar I. Development of small-molecule PUMA inhibitors for mitigating radiation-induced cell death. Current Topics in Medicinal Chemistry. 11: 281-90. PMID 21320058 DOI: 10.2174/156802611794072641 |
0.38 |
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| 2011 |
Sun Q, Zheng X, Zhang L, Yu J. Smac Modulates Chemosensitivity in Head and Neck Cancer Cells through the Mitochondrial Apoptotic Pathway Clinical Cancer Research. 17: 2361-2372. PMID 21242120 DOI: 10.1158/1078-0432.Ccr-10-2262 |
0.431 |
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| 2010 |
Qiu W, Wang X, Leibowitz B, Liu H, Barker N, Okada H, Oue N, Yasui W, Clevers H, Schoen RE, Yu J, Zhang L. Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 107: 20027-32. PMID 21041628 DOI: 10.1073/Pnas.1010430107 |
0.442 |
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| 2010 |
Dudgeon C, Wang P, Sun X, Peng R, Sun Q, Yu J, Zhang L. PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01. Molecular Cancer Therapeutics. 9: 2893-902. PMID 20978166 DOI: 10.1158/1535-7163.Mct-10-0635 |
0.452 |
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| 2010 |
Leibowitz B, Yu J. Mitochondrial signaling in cell death via the Bcl-2 family. Cancer Biology & Therapy. 9: 417-422. PMID 20190564 DOI: 10.4161/Cbt.9.6.11392 |
0.364 |
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| 2010 |
Yu H, Shen H, Yuan Y, XuFeng R, Hu X, Garrison SP, Zhang L, Yu J, Zambetti GP, Cheng T. Deletion of Puma protects hematopoietic stem cells and confers long-term survival in response to high-dose gamma-irradiation. Blood. 115: 3472-80. PMID 20177048 DOI: 10.1182/Blood-2009-10-248278 |
0.343 |
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| 2010 |
Qiu W, Leibowitz B, Zhang L, Yu J. Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis Oncogene. 29: 1622-1632. PMID 19966853 DOI: 10.1038/Onc.2009.451 |
0.405 |
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| 2010 |
Gao J, Senthil M, Ren B, Yan J, Xing Q, Yu J, Zhang L, Yim JH. IRF-1 transcriptionally upregulates PUMA, which mediates the mitochondrial apoptotic pathway in IRF-1-induced apoptosis in cancer cells. Cell Death & Differentiation. 17: 699-709. PMID 19851330 DOI: 10.1038/Cdd.2009.156 |
0.469 |
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| 2010 |
Qiu W, Leibowitz B, Zhang L, Yu J. Abstract 3198: Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis Cancer Research. 70: 3198-3198. DOI: 10.1158/1538-7445.Am10-3198 |
0.429 |
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| 2010 |
Li H, Wang P, Yu J, Zhang L. Abstract 2913: Autophagy resulting from specific ablation of the proapoptotic function of cytochromec Cancer Research. 70: 2913-2913. DOI: 10.1158/1538-7445.Am10-2913 |
0.426 |
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| 2010 |
Sun Q, Zhang L, Yu J. Abstract 1218: SMAC modulates gemcitabine-induced apoptosis in head and neck cancer cells Cancer Research. 70: 1218-1218. DOI: 10.1158/1538-7445.Am10-1218 |
0.473 |
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| 2010 |
Leibowitz BJ, Zhang L, Yu J. Abstract 1203: Coordinated regulation of intestinal radio-sensitivity by PUMA and p21 Cancer Research. 70: 1203-1203. DOI: 10.1158/1538-7445.Am10-1203 |
0.368 |
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| 2009 |
Yu J. PUMA Kills Stem Cells to Stall Cancer Molecular and Cellular Pharmacology. 1: 112-118. PMID 20046541 DOI: 10.4255/Mcpharmacol.09.14 |
0.47 |
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| 2009 |
Wang P, Zou F, Zhang X, Li H, Dulak A, Tomko RJ, Lazo JS, Wang Z, Zhang L, Yu J. microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells. Cancer Research. 69: 8157-65. PMID 19826040 DOI: 10.1158/0008-5472.Can-09-1996 |
0.309 |
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| 2009 |
Yue W, Sun Q, Landreneau R, Wu C, Siegfried JM, Yu J, Zhang L. Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression. Cancer Research. 69: 6339-46. PMID 19584278 DOI: 10.1158/0008-5472.Can-09-0398 |
0.327 |
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| 2009 |
Qiu W, Carson-Walter EB, Kuan SF, Zhang L, Yu J. PUMA suppresses intestinal tumorigenesis in mice. Cancer Research. 69: 4999-5006. PMID 19491259 DOI: 10.1158/0008-5472.Can-09-0262 |
0.414 |
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| 2009 |
Wang P, Qiu W, Dudgeon C, Liu H, Huang C, Zambetti GP, Yu J, Zhang L. PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis Cell Death and Differentiation. 16: 1192-1202. PMID 19444283 DOI: 10.1038/Cdd.2009.51 |
0.357 |
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| 2009 |
Sun Q, Ming L, Thomas SM, Wang Y, Chen ZG, Ferris RL, Grandis JR, Zhang L, Yu J. PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells. Oncogene. 28: 2348-57. PMID 19421143 DOI: 10.1038/Onc.2009.108 |
0.431 |
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| 2008 |
Yu J, Zhang L. PUMA, a potent killer with or without p53 Oncogene. 27. PMID 19641508 DOI: 10.1038/Onc.2009.45 |
0.46 |
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| 2008 |
Chen A, Yu J, Zhang L, Sun Y, Zhang Y, Guo H, Zhou Y, Mitchelson K, Cheng J. Microarray and biochemical analysis of bufalin-induced apoptosis of HL-60 Cells. Biotechnology Letters. 31: 487-94. PMID 19039527 DOI: 10.1007/s10529-008-9888-x |
0.306 |
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| 2008 |
Bank A, Yu J, Zhang L. NSAIDs downregulate Bcl-X(L) and dissociate BAX and Bcl-X(L) to induce apoptosis in colon cancer cells. Nutrition and Cancer. 60: 98-103. PMID 19003586 DOI: 10.1080/01635580802381261 |
0.46 |
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| 2008 |
Ming L, Sakaida T, Yue W, Jha A, Zhang L, Yu J. Sp1 and p73 activate PUMA following serum starvation. Carcinogenesis. 29: 1878-84. PMID 18579560 DOI: 10.1093/Carcin/Bgn150 |
0.438 |
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| 2008 |
Garrison SP, Jeffers JR, Yang C, Nilsson JA, Hall MA, Rehg JE, Yue W, Yu J, Zhang L, Onciu M, Sample JT, Cleveland JL, Zambetti GP. Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis. Molecular and Cellular Biology. 28: 5391-402. PMID 18573879 DOI: 10.1128/Mcb.00907-07 |
0.383 |
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| 2008 |
Qiu W, Carson-Walter EB, Liu H, Epperly M, Greenberger JS, Zambetti GP, Zhang L, Yu J. PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome. Cell Stem Cell. 2: 576-83. PMID 18522850 DOI: 10.1016/J.Stem.2008.03.009 |
0.392 |
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| 2008 |
Dudgeon C, Yu J. Green tea and PUMA: a deadly combination? Cancer Biology & Therapy. 7: 909-910. PMID 18509259 DOI: 10.4161/Cbt.7.6.6317 |
0.456 |
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| 2008 |
Luo W, Liu J, Li J, Zhang D, Liu M, Addo JK, Patil S, Zhang L, Yu J, Buolamwini JK, Chen J, Huang C. Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway. The Journal of Biological Chemistry. 283: 8624-33. PMID 18218619 DOI: 10.1074/Jbc.M707860200 |
0.516 |
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| 2008 |
Bank A, Wang P, Du C, Yu J, Zhang L. SMAC mimetics sensitize nonsteroidal anti-inflammatory drug-induced apoptosis by promoting caspase-3-mediated cytochrome c release. Cancer Research. 68: 276-84. PMID 18172320 DOI: 10.1158/0008-5472.Can-07-5242 |
0.445 |
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| 2008 |
Yue W, Sun Q, Dacic S, Landreneau RJ, Siegfried JM, Yu J, Zhang L. Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer. Carcinogenesis. 29: 84-92. PMID 18048388 DOI: 10.1093/Carcin/Bgm267 |
0.356 |
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| 2007 |
Sun Q, Sakaida T, Yue W, Gollin SM, Yu J. Chemosensitization of head and neck cancer cells by PUMA. Molecular Cancer Therapeutics. 6: 3180-8. PMID 18089712 DOI: 10.1158/1535-7163.Mct-07-0265 |
0.47 |
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| 2007 |
Zhang L, Ming L, Yu J. BH3 mimetics to improve cancer therapy; mechanisms and examples Drug Resistance Updates. 10: 207-217. PMID 17921043 DOI: 10.1016/J.Drup.2007.08.002 |
0.351 |
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| 2007 |
Yue W, Dacic S, Sun Q, Landreneau R, Guo M, Zhou W, Siegfried JM, Yu J, Zhang L. Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 4336-44. PMID 17671114 DOI: 10.1158/1078-0432.Ccr-07-0015 |
0.326 |
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| 2007 |
Ding WX, Ni HM, Chen X, Yu J, Zhang L, Yin XM. A coordinated action of Bax, PUMA, and p53 promotes MG132-induced mitochondria activation and apoptosis in colon cancer cells. Molecular Cancer Therapeutics. 6: 1062-9. PMID 17363499 DOI: 10.1158/1535-7163.Mct-06-0541 |
0.479 |
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| 2007 |
Zhang X, Guo A, Yu J, Possemato A, Chen Y, Zheng W, Polakiewicz RD, Kinzler KW, Vogelstein B, Velculescu VE, Wang ZJ. Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T. Proceedings of the National Academy of Sciences of the United States of America. 104: 4060-4. PMID 17360477 DOI: 10.1073/Pnas.0611665104 |
0.432 |
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| 2007 |
Wang P, Yu J, Zhang L. The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage Proceedings of the National Academy of Sciences of the United States of America. 104: 4054-4059. PMID 17360476 DOI: 10.1073/Pnas.0700020104 |
0.454 |
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| 2007 |
Yu J, Wang P, Ming L, Wood MA, Zhang L. SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events. Oncogene. 26: 4189-4198. PMID 17237824 DOI: 10.1038/Sj.Onc.1210196 |
0.406 |
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| 2007 |
Wu B, Qiu W, Wang P, Yu H, Cheng T, Zambetti GP, Zhang L, Yu J. p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia-reperfusion. Gut. 56: 645-54. PMID 17127703 DOI: 10.1136/Gut.2006.101683 |
0.367 |
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| 2007 |
Hu CA, Donald SP, Yu J, Lin WW, Liu Z, Steel G, Obie C, Valle D, Phang JM. Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis. Molecular and Cellular Biochemistry. 295: 85-92. PMID 16874462 DOI: 10.1007/S11010-006-9276-6 |
0.409 |
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| 2006 |
Yu J, Yue W, Wu B, Zhang L. PUMA Sensitizes Lung Cancer Cells to Chemotherapeutic Agents and Irradiation Clinical Cancer Research. 12: 2928-2936. PMID 16675590 DOI: 10.1158/1078-0432.Ccr-05-2429 |
0.436 |
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| 2006 |
Ming L, Wang P, Bank A, Yu J, Zhang L. PUMA dissociates Bax and Bcl-XL to induce apoptosis in colon cancer cells Journal of Biological Chemistry. 281: 16034-16042. PMID 16608847 DOI: 10.1074/Jbc.M513587200 |
0.439 |
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| 2006 |
Wang H, Qian H, Yu J, Zhang X, Zhang L, Fu M, Liang X, Zhan Q, Lin C. Administration of PUMA adenovirus increases the sensitivity of esophageal cancer cells to anticancer drugs. Cancer Biology & Therapy. 5: 380-385. PMID 16481741 DOI: 10.4161/Cbt.5.4.2477 |
0.458 |
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| 2005 |
Yu J, Zhang L. The transcriptional targets of p53 in apoptosis control. Biochemical and Biophysical Research Communications. 331: 851-858. PMID 15865941 DOI: 10.1016/J.Bbrc.2005.03.189 |
0.465 |
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| 2005 |
Liu Z, Lu H, Shi H, Du Y, Yu J, Gu S, Chen X, Liu KJ, Hu CA. PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells. Cancer Research. 65: 1647-54. PMID 15753358 DOI: 10.1158/0008-5472.Can-04-1754 |
0.425 |
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| 2004 |
Kohli M, Yu J, Seaman C, Bardelli A, Kinzler KW, Vogelstein B, Lengauer C, Zhang L. SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells Proceedings of the National Academy of Sciences of the United States of America. 101: 16897-16902. PMID 15557007 DOI: 10.1073/Pnas.0403405101 |
0.546 |
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| 2004 |
Yu J, Zhang L. Apoptosis in human cancer cells. Current Opinion in Oncology. 16: 19-24. PMID 14685088 DOI: 10.1097/00001622-200401000-00005 |
0.474 |
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| 2003 |
Yu J, Tiwari S, Steiner P, Zhang L. Differential apoptotic response to the proteasome inhibitor Bortezomib [VELCADE, PS-341] in Bax-deficient and p21-deficient colon cancer cells. Cancer Biology & Therapy. 2: 694-9. PMID 14688479 |
0.343 |
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| 2003 |
Macip S, Igarashi M, Berggren P, Yu J, Lee SW, Aaronson SA. Influence of induced reactive oxygen species in p53-mediated cell fate decisions. Molecular and Cellular Biology. 23: 8576-85. PMID 14612402 DOI: 10.1128/Mcb.23.23.8576-8585.2003 |
0.452 |
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| 2003 |
Yu J, Zhang L. No PUMA, no death: Implications for p53-dependent apoptosis Cancer Cell. 4: 248-249. PMID 14585351 DOI: 10.1016/S1535-6108(03)00249-6 |
0.444 |
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| 2003 |
Yu J, Wang Z, Kinzler KW, Vogelstein B, Zhang L. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 1931-6. PMID 12574499 DOI: 10.1073/Pnas.2627984100 |
0.627 |
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| 2003 |
Yu J, Tiwari S, Steiner P, Zhang L. Differential Apoptotic Response to the Proteasome Inhibitor Bortezomib (VELCADETM, PS-341) in Bax-Deficient and p21-Deficient Colon Cancer Cells Cancer Biology & Therapy. 2: 694. DOI: 10.4161/Cbt.2.6.573 |
0.518 |
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| 2002 |
Giannakakou P, Nakano M, Nicolaou KC, O'Brate A, Yu J, Blagosklonny MV, Greber UF, Fojo T. Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics Proceedings of the National Academy of Sciences of the United States of America. 99: 10855-10860. PMID 12145320 DOI: 10.1073/Pnas.132275599 |
0.335 |
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| 2002 |
Zawel L, Yu J, Torrance CJ, Markowitz S, Kinzler KW, Vogelstein B, Zhou S. DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities. Proceedings of the National Academy of Sciences of the United States of America. 99: 2848-53. PMID 11880636 DOI: 10.1073/Pnas.261714999 |
0.466 |
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| 2001 |
Hwang PM, Bunz F, Yu J, Rago C, Chan TA, Murphy MP, Kelso GF, Smith RA, Kinzler KW, Vogelstein B. Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Nature Medicine. 7: 1111-7. PMID 11590433 DOI: 10.1038/Nm1001-1111 |
0.759 |
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| 2001 |
Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B. PUMA induces the rapid apoptosis of colorectal cancer cells. Molecular Cell. 7: 673-82. PMID 11463391 DOI: 10.1016/S1097-2765(01)00213-1 |
0.576 |
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| 2001 |
Zhang L, Yu J, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B. Short mononucleotide repeat sequence variability in mismatch repair-deficient cancers. Cancer Research. 61: 3801-5. PMID 11325855 |
0.464 |
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| 2001 |
Hwang PM, Bunz F, Yu J, Rago C, Chan TA, Murphy MP, Kelso GF, Smith RAJ, Kinzler KW, Vogelstein B. Erratum: Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells (Nature Medicine (2001) 7 (1111-1117)) Nature Medicine. 7. DOI: 10.1038/Nm1101-1255A |
0.751 |
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| 2000 |
Zhang L, Yu J, Park BH, Kinzler KW, Vogelstein B. Role of BAX in the apoptotic response to anticancer agents. Science (New York, N.Y.). 290: 989-92. PMID 11062132 DOI: 10.1126/Science.290.5493.989 |
0.666 |
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| 2000 |
Flatt PM, Polyak K, Tang LJ, Scatena CD, Westfall MD, Rubinstein LA, Yu J, Kinzler KW, Vogelstein B, Hill DE, Pietenpol JA. p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest. Cancer Letters. 156: 63-72. PMID 10840161 DOI: 10.1016/S0304-3835(00)00441-9 |
0.551 |
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| 2000 |
Shih IM, Yu J, He TC, Vogelstein B, Kinzler KW. The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression. Cancer Research. 60: 1671-6. PMID 10749138 |
0.418 |
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| 1999 |
Yu J, Zhang L, Hwang PM, Rago C, Kinzler KW, Vogelstein B. Identification and classification of p53-regulated genes. Proceedings of the National Academy of Sciences of the United States of America. 96: 14517-22. PMID 10588737 DOI: 10.1073/Pnas.96.25.14517 |
0.729 |
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| 1999 |
Velculescu VE, Madden SL, Zhang L, Lash AE, Yu J, Rago C, Lal A, Wang CJ, Beaudry GA, Ciriello KM, Cook BP, Dufault MR, Ferguson AT, Gao Y, He TC, et al. Analysis of human transcriptomes. Nature Genetics. 23: 387-8. PMID 10581018 DOI: 10.1038/70487 |
0.631 |
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| 1999 |
Da Costa LT, He TC, Yu J, Sparks AB, Morin PJ, Polyak K, Laken S, Vogelstein B, Kinzler KW. CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling Oncogene. 18: 5010-5014. PMID 10490837 DOI: 10.1038/Sj.Onc.1202872 |
0.525 |
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| 1998 |
Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B. Mutations of mitotic checkpoint genes in human cancers. Nature. 392: 300-3. PMID 9521327 DOI: 10.1038/32688 |
0.614 |
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| 1998 |
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, Vogelstein B. A simplified system for generating recombinant adenoviruses. Proceedings of the National Academy of Sciences of the United States of America. 95: 2509-14. PMID 9482916 |
0.382 |
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| 1997 |
Waldman T, Zhang Y, Dillehay L, Yu J, Kinzler K, Vogelstein B, Williams J. Cell-cycle arrest versus cell death in cancer therapy. Nature Medicine. 3: 1034-6. PMID 9288734 DOI: 10.1038/Nm0997-1034 |
0.535 |
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| 1994 |
Leach FS, Nicolaides NC, Sistonen P, Yu JW, Kao FT, de la Chapelle A, Kinzler KW, Vogelstein B. Three dinucleotide repeat polymorphisms proximal to the D2S123 locus. Human Molecular Genetics. 3: 2082. PMID 7874140 |
0.311 |
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