| Year |
Citation |
Score |
| 2024 |
Hong JD, Salom D, Choi EH, Du SW, Tworak A, Smidak R, Gao F, Solano YJ, Zhang J, Kiser PD, Palczewski K. Retinylidene Chromophore Hydrolysis from Mammalian Visual and Non-Visual Opsins. The Journal of Biological Chemistry. 105678. PMID 38272218 DOI: 10.1016/j.jbc.2024.105678 |
0.701 |
|
| 2023 |
Wu A, Salom D, Hong JD, Tworak A, Watanabe K, Pardon E, Steyaert J, Kandori H, Katayama K, Kiser PD, Palczewski K. Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nature Communications. 14: 5209. PMID 37626045 DOI: 10.1038/s41467-023-40911-9 |
0.577 |
|
| 2023 |
Tworak A, Kolesnikov AV, Hong JD, Choi EH, Luu JC, Palczewska G, Dong Z, Lewandowski D, Brooks MJ, Campello L, Swaroop A, Kiser PD, Kefalov VJ, Palczewski K. Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia. Cell Reports. 42: 112982. PMID 37585292 DOI: 10.1016/j.celrep.2023.112982 |
0.822 |
|
| 2023 |
Bassetto M, Zaluski J, Li B, Zhang J, Badiee M, Kiser PD, Tochtrop GP. Tuning the Metabolic Stability of Visual Cycle Modulators through Modification of an RPE65 Recognition Motif. Journal of Medicinal Chemistry. PMID 37279401 DOI: 10.1021/acs.jmedchem.3c00461 |
0.378 |
|
| 2023 |
C Luu J, Saadane A, Leinonen H, H Choi E, Gao F, Lewandowski D, Halabi M, L Sander C, Wu A, Wang JM, Singh R, Gao S, Lessieur EM, Dong Z, Palczewska G, ... ... Kiser PD, et al. Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221045120. PMID 37126699 DOI: 10.1073/pnas.2221045120 |
0.649 |
|
| 2022 |
Hong JD, Salom D, Kochman MA, Kubas A, Kiser PD, Palczewski K. Chromophore hydrolysis and release from photoactivated rhodopsin in native membranes. Proceedings of the National Academy of Sciences of the United States of America. 119: e2213911119. PMID 36322748 DOI: 10.1073/pnas.2213911119 |
0.666 |
|
| 2022 |
Huh CYL, Leinonen H, Nakayama T, Tomasello JR, Zhang J, Zeitoun J, Peach JP, Halabi M, Kiser JZ, Palczewski K, Kiser PD, Gandhi SP. Retinoid therapy restores eye-specific cortical responses in adult mice with retinal degeneration. Current Biology : Cb. PMID 36152631 DOI: 10.1016/j.cub.2022.09.005 |
0.65 |
|
| 2021 |
Occelli LM, Daruwalla A, De Silva SR, Winkler PA, Sun K, Pasmanter N, Minella A, Querubin J, Lyons LA, Consortium L, Robson AG, Heon E, Michaelides M, Webster AR, Palczewski K, ... ... Kiser PD, et al. A large animal model of RDH5-associated retinopathy recapitulates important features of the human phenotype. Human Molecular Genetics. PMID 34726233 DOI: 10.1093/hmg/ddab316 |
0.584 |
|
| 2021 |
Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD. Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure (London, England : 1993). PMID 34678158 DOI: 10.1016/j.str.2021.10.002 |
0.782 |
|
| 2021 |
Kiser PD. Retinal pigment epithelium 65 kDa protein (RPE65): An update. Progress in Retinal and Eye Research. 101013. PMID 34607013 DOI: 10.1016/j.preteyeres.2021.101013 |
0.482 |
|
| 2021 |
Sander CL, Sears AE, Pinto AFM, Choi EH, Kahremany S, Gao F, Salom D, Jin H, Pardon E, Suh S, Dong Z, Steyaert J, Saghatelian A, Skowronska-Krawczyk D, Kiser PD, et al. Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition. The Journal of Cell Biology. 220. PMID 34132745 DOI: 10.1083/jcb.202101063 |
0.736 |
|
| 2021 |
Blum E, Zhang J, Zaluski J, Einstein DE, Korshin EE, Kubas A, Gruzman A, Tochtrop GP, Kiser PD, Palczewski K. Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy. Journal of Medicinal Chemistry. PMID 34081480 DOI: 10.1021/acs.jmedchem.1c00279 |
0.641 |
|
| 2021 |
Choi EH, Suh S, Einstein DE, Leinonen H, Dong Z, Ramachandra Rao S, Fliesler SJ, Blackshaw S, Yu M, Peachey NS, Palczewski K, Kiser PD. An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease. Jci Insight. PMID 33784255 DOI: 10.1172/jci.insight.146604 |
0.802 |
|
| 2021 |
Kolesnikov AV, Kiser PD, Palczewski K, Kefalov VJ. Function of mammalian M-cones depends on the level of CRALBP in Müller cells. The Journal of General Physiology. 153. PMID 33216847 DOI: 10.1085/jgp.202012675 |
0.674 |
|
| 2020 |
Kiser PD, Palczewski K. Pathways and disease-causing alterations in visual chromophore production for vertebrate vision. The Journal of Biological Chemistry. PMID 33187985 DOI: 10.1074/jbc.REV120.014405 |
0.691 |
|
| 2020 |
Suh S, Choi EH, Leinonen H, Foik AT, Newby GA, Yeh WH, Dong Z, Kiser PD, Lyon DC, Liu DR, Palczewski K. Publisher Correction: Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing. Nature Biomedical Engineering. PMID 33122854 DOI: 10.1038/s41551-020-00652-2 |
0.79 |
|
| 2020 |
Suh S, Choi EH, Leinonen H, Foik AT, Newby GA, Yeh WH, Dong Z, Kiser PD, Lyon DC, Liu DR, Palczewski K. Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing. Nature Biomedical Engineering. PMID 33077938 DOI: 10.1038/s41551-020-00632-6 |
0.791 |
|
| 2020 |
Sears AE, Albiez S, Gulati S, Wang B, Kiser P, Kovacik L, Engel A, Stahlberg H, Palczewski K. Single particle cryo-EM of the complex between interphotoreceptor retinoid-binding protein and a monoclonal antibody. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32860273 DOI: 10.1096/Fj.202000796Rr |
0.655 |
|
| 2020 |
Palczewski K, Kiser PD. Shedding new light on the generation of the visual chromophore. Proceedings of the National Academy of Sciences of the United States of America. PMID 32759209 DOI: 10.1073/pnas.2008211117 |
0.688 |
|
| 2019 |
Zhang J, Choi EH, Tworak A, Salom D, Leinonen H, Sander CL, Hoang TV, Handa JT, Blackshaw S, Palczewska G, Kiser PD, Palczewski K. Photic generation of 11-cis-retinal in bovine retinal pigment epithelium. The Journal of Biological Chemistry. PMID 31694912 DOI: 10.1074/Jbc.Ra119.011169 |
0.801 |
|
| 2019 |
Kiser PD, Kolesnikov AV, Kiser JZ, Dong Z, Chaurasia B, Wang L, Summers SA, Hoang T, Blackshaw S, Peachey NS, Kefalov VJ, Palczewski K. Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802493R. PMID 30645148 DOI: 10.1096/Fj.201802493R |
0.68 |
|
| 2018 |
Daruwalla A, Choi EH, Palczewski K, Kiser PD. Structural biology of 11-retinaldehyde production in the classical visual cycle. The Biochemical Journal. 475: 3171-3188. PMID 30352831 DOI: 10.1042/Bcj20180193 |
0.795 |
|
| 2018 |
Gulati S, Jin H, Masuho I, Orban T, Cai Y, Pardon E, Martemyanov KA, Kiser PD, Stewart PL, Ford CP, Steyaert J, Palczewski K. Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor. Nature Communications. 9: 1996. PMID 29777099 DOI: 10.1038/S41467-018-04432-0 |
0.542 |
|
| 2018 |
Choi EH, Suh S, Sander CL, Hernandez CJO, Bulman ER, Khadka N, Dong Z, Shi W, Palczewski K, Kiser PD. Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65. Human Molecular Genetics. PMID 29659842 DOI: 10.1093/Hmg/Ddy128 |
0.788 |
|
| 2018 |
Kiser PD, Zhang J, Sharma A, Angueyra JM, Kolesnikov AV, Badiee M, Tochtrop GP, Kinoshita J, Peachey NS, Li W, Kefalov VJ, Palczewski K. Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function. The Journal of General Physiology. PMID 29500274 DOI: 10.1085/Jgp.201711815 |
0.662 |
|
| 2017 |
Orban T, Leinonen H, Getter T, Dong Z, Sun W, Gao S, Veenstra A, Heidari-Torkabadi H, Kern TS, Kiser PD, Palczewski K. A therapeutic combination of GPCR modulators that protects photoreceptors from degeneration. The Journal of Pharmacology and Experimental Therapeutics. PMID 29162627 DOI: 10.1124/Jpet.117.245167 |
0.648 |
|
| 2017 |
Sui X, Weitz AC, Farquhar ER, Badiee M, Banerjee S, von Lintig J, Tochtrop G, Palczewski K, Hendrich MP, Kiser PD. Structure and spectroscopy of alkene-cleaving dioxygenases containing an atypically coordinated non-heme iron center. Biochemistry. PMID 28493664 DOI: 10.1021/Acs.Biochem.7B00251 |
0.502 |
|
| 2017 |
Kiser PD, Zhang J, Badiee M, Kinoshita J, Peachey NS, Tochtrop GP, Palczewski K. Rational tuning of visual cycle modulator pharmacodynamics. The Journal of Pharmacology and Experimental Therapeutics. PMID 28476927 DOI: 10.1124/Jpet.117.240721 |
0.663 |
|
| 2017 |
Gulati S, Jastrzebska B, Banerjee S, Placeres ÁL, Miszta P, Gao S, Gunderson K, Tochtrop GP, Filipek S, Katayama K, Kiser PD, Mogi M, Stewart PL, Palczewski K. Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism. Proceedings of the National Academy of Sciences of the United States of America. PMID 28289214 DOI: 10.1073/Pnas.1617446114 |
0.651 |
|
| 2016 |
Kiser PD, Palczewski K. Retinoids and Retinal Diseases. Annual Review of Vision Science. 2: 197-234. PMID 27917399 DOI: 10.1146/annurev-vision-111815-114407 |
0.633 |
|
| 2016 |
Chen Y, Kern TS, Kiser PD, Palczewski K. Eyes on systems pharmacology. Pharmacological Research. PMID 27720767 DOI: 10.1016/J.Phrs.2016.09.026 |
0.503 |
|
| 2016 |
Chen Y, Palczewska G, Masuho I, Gao S, Jin H, Dong Z, Gieser L, Brooks MJ, Kiser PD, Kern TS, Martemyanov KA, Swaroop A, Palczewski K. Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration. Science Signaling. 9: ra74. PMID 27460988 DOI: 10.1126/Scisignal.Aag0245 |
0.629 |
|
| 2016 |
Sui X, Zhang J, Golczak M, Palczewski K, Kiser PD. Key residues for catalytic function and metal coordination in a carotenoid cleavage dioxygenase. The Journal of Biological Chemistry. PMID 27453555 DOI: 10.1074/Jbc.M116.744912 |
0.571 |
|
| 2016 |
Han X, Tang J, Wang J, Ren F, Zheng J, Gragg M, Kiser P, Park PS, Palczewski K, Yao X, Zhang Y. Conformational change of human checkpoint kinase 1 (Chk1) induced by DNA damage. The Journal of Biological Chemistry. PMID 27129240 DOI: 10.1074/Jbc.M115.713248 |
0.524 |
|
| 2016 |
Babino D, Golczak M, Kiser PD, Wyss A, Palczewski K, von Lintig J. The biochemical basis of vitamin A3 production in arthropod vision. Acs Chemical Biology. PMID 26811964 DOI: 10.1021/Acschembio.5B00967 |
0.592 |
|
| 2015 |
Sui X, Golczak M, Zhang J, Kleinberg KA, von Lintig J, Palczewski K, Kiser PD. Utilization of Dioxygen by Carotenoid Cleavage Oxygenases. The Journal of Biological Chemistry. PMID 26499794 DOI: 10.1074/Jbc.M115.696799 |
0.528 |
|
| 2015 |
Zhang J, Kiser PD, Badiee M, Palczewska G, Dong Z, Golczak M, Tochtrop GP, Palczewski K. Molecular pharmacodynamics of emixustat in protection against retinal degeneration. The Journal of Clinical Investigation. 125: 2781-94. PMID 26075817 DOI: 10.1172/Jci80950 |
0.686 |
|
| 2015 |
Kiser PD, Zhang J, Badiee M, Li Q, Shi W, Sui X, Golczak M, Tochtrop GP, Palczewski K. Catalytic mechanism of a retinoid isomerase essential for vertebrate vision. Nature Chemical Biology. 11: 409-15. PMID 25894083 DOI: 10.1038/Nchembio.1799 |
0.664 |
|
| 2015 |
Golczak M, Sears AE, Kiser PD, Palczewski K. LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3. Nature Chemical Biology. 11: 26-32. PMID 25383759 DOI: 10.1038/Nchembio.1687 |
0.586 |
|
| 2014 |
Chen Y, Tang H, Seibel W, Papoian R, Oh K, Li X, Zhang J, Golczak M, Palczewski K, Kiser PD. Identification and characterization of novel inhibitors of Mammalian aspartyl aminopeptidase. Molecular Pharmacology. 86: 231-42. PMID 24913940 DOI: 10.1124/Mol.114.093070 |
0.586 |
|
| 2014 |
Sui X, Kiser PD, Che T, Carey PR, Golczak M, Shi W, von Lintig J, Palczewski K. Analysis of carotenoid isomerase activity in a prototypical carotenoid cleavage enzyme, apocarotenoid oxygenase (ACO). The Journal of Biological Chemistry. 289: 12286-99. PMID 24648526 DOI: 10.1074/Jbc.M114.552836 |
0.561 |
|
| 2014 |
Kiser PD, Golczak M, Palczewski K. Chemistry of the retinoid (visual) cycle. Chemical Reviews. 114: 194-232. PMID 23905688 DOI: 10.1021/Cr400107Q |
0.653 |
|
| 2013 |
Sui X, Kiser PD, Lintig Jv, Palczewski K. Structural basis of carotenoid cleavage: from bacteria to mammals. Archives of Biochemistry and Biophysics. 539: 203-13. PMID 23827316 DOI: 10.1016/J.Abb.2013.06.012 |
0.58 |
|
| 2013 |
Kowatz T, Babino D, Kiser P, Palczewski K, von Lintig J. Characterization of human β,β-carotene-15,15'-monooxygenase (BCMO1) as a soluble monomeric enzyme. Archives of Biochemistry and Biophysics. 539: 214-22. PMID 23727499 DOI: 10.1016/J.Abb.2013.05.007 |
0.572 |
|
| 2013 |
Palczewski K, Kiser PD. Biochemistry. As good as chocolate. Science (New York, N.Y.). 340: 562-3. PMID 23641106 DOI: 10.1126/Science.1238521 |
0.501 |
|
| 2012 |
Kiser PD, Farquhar ER, Shi W, Sui X, Chance MR, Palczewski K. Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis. Proceedings of the National Academy of Sciences of the United States of America. 109: E2747-56. PMID 23012475 DOI: 10.1073/Pnas.1212025109 |
0.577 |
|
| 2012 |
Golczak M, Kiser PD, Sears AE, Lodowski DT, Blaner WS, Palczewski K. Structural basis for the acyltransferase activity of lecithin:retinol acyltransferase-like proteins. The Journal of Biological Chemistry. 287: 23790-807. PMID 22605381 DOI: 10.1074/Jbc.M112.361550 |
0.572 |
|
| 2012 |
Chen Y, Farquhar ER, Chance MR, Palczewski K, Kiser PD. Insights into substrate specificity and metal activation of mammalian tetrahedral aspartyl aminopeptidase. The Journal of Biological Chemistry. 287: 13356-70. PMID 22356908 DOI: 10.1074/Jbc.M112.347518 |
0.601 |
|
| 2012 |
Kiser PD, Golczak M, Maeda A, Palczewski K. Key enzymes of the retinoid (visual) cycle in vertebrate retina. Biochimica Et Biophysica Acta. 1821: 137-51. PMID 21447403 DOI: 10.1016/J.Bbalip.2011.03.005 |
0.69 |
|
| 2010 |
Kiser PD, Palczewski K. Membrane-binding and enzymatic properties of RPE65. Progress in Retinal and Eye Research. 29: 428-42. PMID 20304090 DOI: 10.1016/J.Preteyeres.2010.03.002 |
0.663 |
|
| 2010 |
von Lintig J, Kiser PD, Golczak M, Palczewski K. The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision. Trends in Biochemical Sciences. 35: 400-10. PMID 20188572 DOI: 10.1016/J.Tibs.2010.01.005 |
0.582 |
|
| 2010 |
Golczak M, Kiser PD, Lodowski DT, Maeda A, Palczewski K. Importance of membrane structural integrity for RPE65 retinoid isomerization activity. The Journal of Biological Chemistry. 285: 9667-82. PMID 20100834 DOI: 10.1074/Jbc.M109.063941 |
0.656 |
|
| 2010 |
Bereta G, Wang B, Kiser PD, Baehr W, Jang GF, Palczewski K. A functional kinase homology domain is essential for the activity of photoreceptor guanylate cyclase 1. The Journal of Biological Chemistry. 285: 1899-908. PMID 19901021 DOI: 10.1074/Jbc.M109.061713 |
0.58 |
|
| 2009 |
Kiser PD, Lorimer GH, Palczewski K. Use of thallium to identify monovalent cation binding sites in GroEL. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 967-71. PMID 19851000 DOI: 10.1107/S1744309109032928 |
0.518 |
|
| 2009 |
Kiser PD, Golczak M, Lodowski DT, Chance MR, Palczewski K. Crystal structure of native RPE65, the retinoid isomerase of the visual cycle. Proceedings of the National Academy of Sciences of the United States of America. 106: 17325-30. PMID 19805034 DOI: 10.1073/Pnas.0906600106 |
0.704 |
|
| 2008 |
Bereta G, Kiser PD, Golczak M, Sun W, Heon E, Saperstein DA, Palczewski K. Impact of retinal disease-associated RPE65 mutations on retinoid isomerization. Biochemistry. 47: 9856-65. PMID 18722466 DOI: 10.1021/Bi800905V |
0.615 |
|
| 2008 |
Golczak M, Maeda A, Bereta G, Maeda T, Kiser PD, Hunzelmann S, von Lintig J, Blaner WS, Palczewski K. Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. The Journal of Biological Chemistry. 283: 9543-54. PMID 18195010 DOI: 10.1074/Jbc.M708982200 |
0.672 |
|
| 2008 |
Moise AR, DomÃnguez M, Alvarez S, Alvarez R, Schupp M, Cristancho AG, Kiser PD, de Lera AR, Lazar MA, Palczewski K. Stereospecificity of retinol saturase: absolute configuration, synthesis, and biological evaluation of dihydroretinoids. Journal of the American Chemical Society. 130: 1154-5. PMID 18179220 DOI: 10.1021/Ja710487Q |
0.517 |
|
| 2007 |
Kiser PD, Lodowski DT, Palczewski K. Purification, crystallization and structure determination of native GroEL from Escherichia coli lacking bound potassium ions. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 457-61. PMID 17554162 DOI: 10.1107/S1744309107020295 |
0.515 |
|
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