Irene H. Cheng - Publications

Affiliations: 
Yang-Ming University, Allendale Charter Township, Taipei City, Taiwan 
Area:
Alzheimer's disease
Website:
http://bml.ym.edu.tw/ibs/brain/hjcheng.htm

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Devina T, Wong YH, Hsiao CW, Li YJ, Lien CC, Cheng IH. Endoplasmic reticulum stress induces Alzheimer disease-like phenotypes in the neuron derived from the induced pluripotent stem cell with D678H mutation on amyloid precursor protein. Journal of Neurochemistry. PMID 35943292 DOI: 10.1111/jnc.15687  0.725
2021 Deng SM, Chen CJ, Lin HL, Cheng IH. The beneficial effect of synbiotics consumption on Alzheimer's disease mouse model via reducing local and systemic inflammation. Iubmb Life. PMID 34962691 DOI: 10.1002/iub.2589  0.452
2021 Lee ZF, Huang TH, Chen SP, Cheng IH. Altered nociception in Alzheimer's disease is associated with STEP signaling. Pain. PMID 33433143 DOI: 10.1097/j.pain.0000000000002180  0.448
2020 Chen TB, Lai YH, Ke TL, Chen JP, Lee YJ, Lin SY, Lin PC, Wang PN, Cheng IH. Changes in Plasma Amyloid and Tau in a Longitudinal Study of Normal Aging, Mild Cognitive Impairment, and Alzheimer's Disease. Dementia and Geriatric Cognitive Disorders. 1-16. PMID 31991443 DOI: 10.1159/000505435  0.335
2019 Wu PC, Fann MJ, Tran TT, Chen SC, Devina T, Cheng IH, Lien CC, Kao LS, Wang SJ, Fuh JL, Tzeng TT, Huang CY, Shiao YJ, Wong YH. Assessing the therapeutic potential of Graptopetalum paraguayense on Alzheimer's disease using patient iPSC-derived neurons. Scientific Reports. 9: 19301. PMID 31848379 DOI: 10.1038/S41598-019-55614-9  0.712
2019 Chen TB, Lee YJ, Lin SY, Chen JP, Hu CJ, Wang PN, Cheng IH. Plasma Aβ42 and Total Tau Predict Cognitive Decline in Amnestic Mild Cognitive Impairment. Scientific Reports. 9: 13984. PMID 31562355 DOI: 10.1038/s41598-019-50315-9  0.42
2019 Devina T, Cheng IH. The dominant negative effect of Taiwanese APP mutation revealed by induced neuron from patient's iPSC Ibro Reports. 6. DOI: 10.1016/J.Ibror.2019.07.1139  0.422
2018 Kuo LC, Song YQ, Yao CA, Cheng IH, Chien CT, Lee GC, Yang WC, Lin Y. Ginkgolide A prevents the Aβ-induced depolarization of cortical neurons. Journal of Agricultural and Food Chemistry. PMID 30541279 DOI: 10.1021/Acs.Jafc.8B04514  0.454
2018 Tai YH, Lin YY, Wang KC, Chang CL, Chen RY, Wu CC, Cheng IH. Curcuminoid submicron particle ameliorates cognitive deficits and decreases amyloid pathology in Alzheimer's disease mouse model. Oncotarget. 9: 10681-10697. PMID 29535835 DOI: 10.18632/oncotarget.24369  0.558
2017 Zhao Y, Li X, Huang T, Jiang LL, Tan Z, Zhang M, Cheng IH, Wang X, Bu G, Zhang YW, Wang Q, Xu H. Intracellular trafficking of TREM2 is regulated by presenilin 1. Experimental & Molecular Medicine. 49: e405. PMID 29611543 DOI: 10.1038/Emm.2017.200  0.435
2017 Liu YL, Chen WT, Lin YY, Lu PH, Hsieh SL, Cheng IH. Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model. Molecular Neurodegeneration. 12: 30. PMID 28438208 DOI: 10.1186/s13024-017-0173-0  0.554
2015 Wu YY, Hsu JL, Wang HC, Wu SJ, Hong CJ, Cheng IH. Alterations of the Neuroinflammatory Markers IL-6 and TRAIL in Alzheimer's Disease. Dementia and Geriatric Cognitive Disorders Extra. 5: 424-34. PMID 26675645 DOI: 10.1159/000439214  0.361
2015 Chang WH, Chen MC, Cheng IH. Antroquinonol Lowers Brain Amyloid-β Levels and Improves Spatial Learning and Memory in a Transgenic Mouse Model of Alzheimer's Disease. Scientific Reports. 5: 15067. PMID 26469245 DOI: 10.1038/srep15067  0.558
2015 Hsu BY, Hung WL, Ho CT, Cheng IH, Hwang LS. Protective effects of sesamol and ferulic acid on the formation of endogenous trans-arachidonic acid in hAPP J20 mice Journal of Functional Foods. 16: 378-385. DOI: 10.1016/J.Jff.2015.04.035  0.49
2014 Chen WT, Hsieh YF, Huang YJ, Lin CC, Lin YT, Liu YC, Lien CC, Cheng IH. G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation. Molecular Neurobiology. PMID 25394380 DOI: 10.1007/S12035-014-8969-1  0.376
2014 Fang YS, Tsai KJ, Chang YJ, Kao P, Woods R, Kuo PH, Wu CC, Liao JY, Chou SC, Lin V, Jin LW, Yuan HS, Cheng IH, Tu PH, Chen YR. Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients. Nature Communications. 5: 4824. PMID 25215604 DOI: 10.1038/Ncomms5824  0.528
2014 Lin YC, Wang JY, Wang KC, Liao JY, Cheng IH. Differential regulation of amyloid precursor protein sorting with pathological mutations results in a distinct effect on amyloid-β production. Journal of Neurochemistry. 131: 407-12. PMID 25053581 DOI: 10.1111/jnc.12829  0.584
2013 Huang CW, Wang SJ, Wu SJ, Yang CC, Huang MW, Lin CH, Cheng IH. Potential blood biomarker for disease severity in the Taiwanese population with Alzheimer's disease. American Journal of Alzheimer's Disease and Other Dementias. 28: 75-83. PMID 23230229 DOI: 10.1177/1533317512467674  0.458
2012 Chu YF, Chang WH, Black RM, Liu JR, Sompol P, Chen Y, Wei H, Zhao Q, Cheng IH. Crude caffeine reduces memory impairment and amyloid β(1-42) levels in an Alzheimer's mouse model. Food Chemistry. 135: 2095-102. PMID 22953961 DOI: 10.1016/j.foodchem.2012.04.148  0.552
2012 Chen WT, Hong CJ, Lin YT, Chang WH, Huang HT, Liao JY, Chang YJ, Hsieh YF, Cheng CY, Liu HC, Chen YR, Cheng IH. Amyloid-beta (Aβ) D7H mutation increases oligomeric Aβ42 and alters properties of Aβ-zinc/copper assemblies. Plos One. 7: e35807. PMID 22558227 DOI: 10.1371/Journal.Pone.0035807  0.491
2012 Hsieh Y, Wu Y, Cheng IH. The characterization of presenilin 1 with G206D mutation associated with familial Alzheimer's disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.860  0.41
2011 Cheng IH, Lin YC, Hwang E, Huang HT, Chang WH, Liu YL, Chao CY. Collagen VI protects against neuronal apoptosis elicited by ultraviolet irradiation via an Akt/phosphatidylinositol 3-kinase signaling pathway. Neuroscience. 183: 178-88. PMID 21459131 DOI: 10.1016/j.neuroscience.2011.03.057  0.334
2011 Wu YY, Cheng IH, Lee CC, Chiu MJ, Lee MJ, Chen TF, Hsu JL. Clinical phenotype of G206D mutation in the presenilin 1 gene in pathologically confirmed familial Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 25: 145-50. PMID 21335660 DOI: 10.3233/JAD-2011-102031  0.451
2011 Chen WT, Liao YH, Yu HM, Cheng IH, Chen YR. Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation. The Journal of Biological Chemistry. 286: 9646-56. PMID 21216965 DOI: 10.1074/Jbc.M110.177246  0.343
2011 Lien C, Liu Y, Cheng IH. Impaired somatic inhibition in mature granule cells in an animal model of Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1665  0.419
2009 Chu YF, Brown PH, Lyle BJ, Chen Y, Black RM, Williams CE, Lin YC, Hsu CW, Cheng IH. Roasted coffees high in lipophilic antioxidants and chlorogenic acid lactones are more neuroprotective than green coffees. Journal of Agricultural and Food Chemistry. 57: 9801-8. PMID 19772322 DOI: 10.1021/Jf902095Z  0.616
2009 Meilandt WJ, Cisse M, Ho K, Wu T, Esposito LA, Scearce-Levie K, Cheng IH, Yu GQ, Mucke L. Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1977-86. PMID 19228952 DOI: 10.1523/JNEUROSCI.2984-08.2009  0.789
2009 Cheng JS, Dubal DB, Kim DH, Legleiter J, Cheng IH, Yu GQ, Tesseur I, Wyss-Coray T, Bonaldo P, Mucke L. Collagen VI protects neurons against Abeta toxicity. Nature Neuroscience. 12: 119-21. PMID 19122666 DOI: 10.1038/Nn.2240  0.798
2008 Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nature Neuroscience. 11: 1311-8. PMID 18931664 DOI: 10.1038/Nn.2213  0.804
2008 Cheng JS, Cheng IH, Kim DH, Wu T, Tesseur I, Wyss-Coray T, Bonaldo P, Scearce-Levie K, Mucke L. P1-413: Collagen VI protects neurons against amyloid-beta toxicity Alzheimer's & Dementia. 4: T340-T340. DOI: 10.1016/J.Jalz.2008.05.995  0.763
2008 Sanchez-Mejia RO, Newman JW, Toh S, Yu G, Zhou Y, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. O4-02-03: Phospholipase A2 reduction ameliorates cognitive deficits in mouse model of Alzheimer's disease Alzheimer's & Dementia. 4: T186-T187. DOI: 10.1016/J.Jalz.2008.05.511  0.738
2007 Cheng IH, Scearce-Levie K, Legleiter J, Palop JJ, Gerstein H, Bien-Ly N, Puoliväli J, Lesné S, Ashe KH, Muchowski PJ, Mucke L. Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models. The Journal of Biological Chemistry. 282: 23818-28. PMID 17548355 DOI: 10.1074/Jbc.M701078200  0.809
2007 Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu GQ, Mucke L. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science (New York, N.Y.). 316: 750-4. PMID 17478722 DOI: 10.1126/Science.1141736  0.82
2006 Ji ZS, Müllendorff K, Cheng IH, Miranda RD, Huang Y, Mahley RW. Reactivity of apolipoprotein E4 and amyloid beta peptide: lysosomal stability and neurodegeneration. The Journal of Biological Chemistry. 281: 2683-92. PMID 16298992 DOI: 10.1074/Jbc.M506646200  0.426
2004 Cheng IH, Palop JJ, Esposito LA, Bien-Ly N, Yan F, Mucke L. Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation. Nature Medicine. 10: 1190-2. PMID 15502844 DOI: 10.1038/Nm1123  0.78
2004 Cheng IH, Palop J, Bien-Ly N, Yan F, Mucke L. P2-113 Aggressive brain amyloidosis in transgenic mice expressing human amyloid peptides with the arctic mutations Neurobiology of Aging. 25: S256-S257. DOI: 10.1016/S0197-4580(04)80860-1  0.735
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