Year |
Citation |
Score |
2023 |
Park MY, Kim S, Kwon NH, Moon G, Cha J, Kwon I. Enhanced anti-tumor activity of arginine decarboxylase through the incorporation of aromatic amino acids at the multimer forming interface. Biotechnology Journal. e2300453. PMID 37899497 DOI: 10.1002/biot.202300453 |
0.327 |
|
2021 |
Yang B, Kwon I. Chemical Modification of Cysteine with 3-Arylpropriolonitrile Improves the In Vivo Stability of Albumin-Conjugated Urate Oxidase Therapeutic Protein. Biomedicines. 9. PMID 34680451 DOI: 10.3390/biomedicines9101334 |
0.393 |
|
2021 |
Yang B, Kwon I. Thermostable and Long-Circulating Albumin-Conjugated Urate Oxidase. Pharmaceutics. 13. PMID 34452259 DOI: 10.3390/pharmaceutics13081298 |
0.374 |
|
2021 |
Yang B, Kwon I. Multivalent Albumin-Neonatal Fc Receptor Interactions Mediate a Prominent Extension of the Serum Half-Life of a Therapeutic Protein. Molecular Pharmaceutics. PMID 33983743 DOI: 10.1021/acs.molpharmaceut.1c00231 |
0.341 |
|
2020 |
Cho J, Park J, Tae G, Jin MS, Kwon I. The Minimal Effect of Linker Length for Fatty Acid Conjugation to a Small Protein on the Serum Half-Life Extension. Biomedicines. 8. PMID 32357510 DOI: 10.3390/Biomedicines8050096 |
0.36 |
|
2020 |
Cho J, Park J, Kim S, Kim JC, Tae G, Jin MS, Kwon I. Intramolecular distance in the conjugate of urate oxidase and fatty acid governs FcRn binding and serum half-life in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32006589 DOI: 10.1016/j.jconrel.2020.01.034 |
0.33 |
|
2018 |
Cha J, Kwon I. Purification-Free, Target-Selective Immobilization of a Protein from Cell Lysates. Biotechnology Journal. PMID 29485238 DOI: 10.1002/biot.201700739 |
0.315 |
|
2017 |
Cho J, Lim SI, Yang BS, Hahn YS, Kwon I. Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation. Scientific Reports. 7: 18041. PMID 29269881 DOI: 10.1038/S41598-017-18029-Y |
0.747 |
|
2017 |
Jung S, Kwon I. Synergistic Degradation of a Hyperuricemia-Causing Metabolite Using One-Pot Enzyme-Nanozyme Cascade Reactions. Scientific Reports. 7: 44330. PMID 28287162 DOI: 10.1038/srep44330 |
0.309 |
|
2017 |
Kwon I, Yang B. Bioconjugation and Active Site Design of Enzymes Using Non-natural Amino Acids Industrial & Engineering Chemistry Research. 56: 6535-6547. DOI: 10.1021/ACS.IECR.7B00612 |
0.417 |
|
2016 |
Lim SI, Yang B, Jung Y, Cha J, Cho J, Choi ES, Kim YH, Kwon I. Controlled Orientation of Active Sites in a Nanostructured Multienzyme Complex. Scientific Reports. 6: 39587. PMID 28004799 DOI: 10.1038/srep39587 |
0.729 |
|
2016 |
Yang ST, Lim SI, Kiessling V, Kwon I, Tamm LK. Site-specific fluorescent labeling to visualize membrane translocation of a myristoyl switch protein. Scientific Reports. 6: 32866. PMID 27605302 DOI: 10.1038/Srep32866 |
0.71 |
|
2016 |
Yang B, Lim SI, Kim JC, Tae G, Kwon I. Site-Specific Albumination As an Alternative to PEGylation for the Enhanced Serum Half-Life In Vivo. Biomacromolecules. PMID 27050863 DOI: 10.1021/acs.biomac.6b00238 |
0.706 |
|
2016 |
Kwon I, Choi ES. Forced Ambiguity of the Leucine Codons for Multiple-Site-Specific Incorporation of a Noncanonical Amino Acid. Plos One. 11: e0152826. PMID 27028506 DOI: 10.1371/journal.pone.0152826 |
0.439 |
|
2016 |
Jung S, Kwon I. Expansion of bioorthogonal chemistries towards site-specific polymer-protein conjugation Polymer Chemistry. 7: 4584-4598. DOI: 10.1039/c6py00856a |
0.312 |
|
2015 |
Wong HE, Kwon I. Effects of Non-Natural Amino Acid Incorporation into the Enzyme Core Region on Enzyme Structure and Function. International Journal of Molecular Sciences. 16: 22735-53. PMID 26402667 DOI: 10.3390/ijms160922735 |
0.473 |
|
2015 |
Lim SI, Cho J, Kwon I. Double clicking for site-specific coupling of multiple enzymes. Chemical Communications (Cambridge, England). PMID 26191550 DOI: 10.1039/c5cc04611d |
0.738 |
|
2015 |
Lim SI, Kwon I. Bioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids. Critical Reviews in Biotechnology. 1-13. PMID 26036278 DOI: 10.3109/07388551.2015.1048504 |
0.747 |
|
2015 |
Lim SI, Hahn YS, Kwon I. Site-specific albumination of a therapeutic protein with multi-subunit to prolong activity in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 207: 93-100. PMID 25862515 DOI: 10.1016/J.Jconrel.2015.04.004 |
0.77 |
|
2015 |
Lim SI, Yoon S, Kim YH, Kwon I. Site-specific bioconjugation of an organometallic electron mediator to an enzyme with retained photocatalytic cofactor regenerating capacity and enzymatic activity. Molecules (Basel, Switzerland). 20: 5975-86. PMID 25853315 DOI: 10.3390/molecules20045975 |
0.719 |
|
2015 |
Kwon I, Lim SI. Tailoring the substrate specificity of yeast phenylalanyl-tRNA synthetase toward a phenylalanine analog using multiple-site-specific incorporation. Acs Synthetic Biology. 4: 634-43. PMID 25268049 DOI: 10.1021/sb500309r |
0.743 |
|
2015 |
Wong HE, Kwon I. Effects of non-natural amino acid incorporation into the enzyme core region on enzyme structure and function International Journal of Molecular Sciences. 16: 22735-22753. DOI: 10.3390/ijms160922735 |
0.316 |
|
2015 |
Kwon I, Lim SI. Tailoring the Substrate Specificity of Yeast Phenylalanyl-tRNA Synthetase toward a Phenylalanine Analog Using Multiple-Site-Specific Incorporation Acs Synthetic Biology. 4: 634-643. DOI: 10.1021/sb500309r |
0.735 |
|
2015 |
Lim SI, Hahn YS, Kwon I. Site-specific albumination of a therapeutic protein with multi-subunit to prolong activity in vivo Journal of Controlled Release. 207: 93-100. DOI: 10.1016/j.jconrel.2015.04.004 |
0.742 |
|
2015 |
Zheng S, Lim SI, Kwon I. Manipulating the substrate specificity of murine dihydrofolate reductase enzyme using an expanded set of amino acids Biochemical Engineering Journal. 99: 85-92. DOI: 10.1016/j.bej.2015.03.011 |
0.714 |
|
2014 |
Lim SI, Mizuta Y, Takasu A, Kim YH, Kwon I. Site-specific bioconjugation of a murine dihydrofolate reductase enzyme by copper(I)-catalyzed azide-alkyne cycloaddition with retained activity. Plos One. 9: e98403. PMID 24887377 DOI: 10.1371/journal.pone.0098403 |
0.752 |
|
2013 |
Lim SI, Mizuta Y, Takasu A, Hahn YS, Kim YH, Kwon I. Site-specific fatty acid-conjugation to prolong protein half-life in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 170: 219-25. PMID 23735573 DOI: 10.1016/J.Jconrel.2013.05.023 |
0.76 |
|
2013 |
Zheng S, Kwon I. Controlling enzyme inhibition using an expanded set of genetically encoded amino acids. Biotechnology and Bioengineering. 110: 2361-70. PMID 23568807 DOI: 10.1002/bit.24911 |
0.375 |
|
2013 |
Kwon I, Lim SI. Non-natural amino acids for protein engineering and new protein chemistries Macromolecular Chemistry and Physics. 214: 1295-1301. DOI: 10.1002/macp.201200710 |
0.723 |
|
2012 |
Zheng S, Kwon I. Manipulation of enzyme properties by noncanonical amino acid incorporation. Biotechnology Journal. 7: 47-60. PMID 22121038 DOI: 10.1002/biot.201100267 |
0.439 |
|
2008 |
Kwon I, Schaffer DV. Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transfer. Pharmaceutical Research. 25: 489-99. PMID 17763830 DOI: 10.1007/S11095-007-9431-0 |
0.303 |
|
2007 |
Kwon I, Tirrell DA. Site-specific incorporation of tryptophan analogues into recombinant proteins in bacterial cells. Journal of the American Chemical Society. 129: 10431-7. PMID 17685515 DOI: 10.1021/Ja071773R |
0.616 |
|
2006 |
Kwon I, Wang P, Tirrell DA. Design of a bacterial host for site-specific incorporation of p-bromophenylalanine into recombinant proteins. Journal of the American Chemical Society. 128: 11778-83. PMID 16953616 DOI: 10.1021/Ja0626281 |
0.697 |
|
2003 |
Kwon I, Kirshenbaum K, Tirrell DA. Breaking the degeneracy of the genetic code. Journal of the American Chemical Society. 125: 7512-3. PMID 12812480 DOI: 10.1021/Ja0350076 |
0.502 |
|
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