Jeffrey Deschamps
Affiliations: | 1988-1996 | Lab for Structure of Matter | U.S. Naval Research Laboratory, Washington, DC, United States |
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| Li F, Kopajtic TA, Katz JL, et al. (2022) Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans. Molecules (Basel, Switzerland). 27 |
| Kuskovsky R, Lloyd D, Arora K, et al. (2019) C4-Phenylthio β-lactams: Effect of the chirality of the β-lactam ring on antimicrobial activity. Bioorganic & Medicinal Chemistry. 115050 |
| Iyer MR, Cinar R, Liu J, et al. (2015) Structural Basis of Species-Dependent Differential Affinity of 6-Alkoxy-5-Aryl-3-Pyridinecarboxamide Cannabinoid-1 Receptor Antagonists. Molecular Pharmacology. 88: 238-44 |
| Iyer MR, Lee YS, Deschamps JR, et al. (2012) Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selective μ-antagonist activity. European Journal of Medicinal Chemistry. 50: 44-54 |
| Edwankar RV, Edwankar CR, Deschamps J, et al. (2011) Regiospecific, enantiospecific total synthesis of C-19 methyl substituted sarpagine alkaloids dihydroperaksine-17-al and dihydroperaksine. Organic Letters. 13: 5216-9 |
| Konaklieva MI, Suwandi LS, Kostova M, et al. (2011) 4,4-Bis(methylthio)azetidin-2-ones as synthons of 1,2- and 1,3-dicarbonyl systems Tetrahedron Letters. 52: 1909-1912 |
| Zhang Y, Lee YS, Rothman RB, et al. (2009) Probes for narcotic receptor mediated phenomena. 39. Enantiomeric n-substituted benzofuro[2,3-c]pyridin-6-ols: synthesis and topological relationship to oxide-bridged phenylmorphans Journal of Medicinal Chemistry. 52: 7570-7579 |
| Zezula J, Singer L, Przybył AK, et al. (2008) Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans. Organic & Biomolecular Chemistry. 6: 2868-83 |
| Smith ED, Ariane Vinson N, Zhong D, et al. (2008) A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay. Bioorganic & Medicinal Chemistry. 16: 822-9 |
| McElroy T, Thomas JB, Brine GA, et al. (2008) A Practical Synthesis of the Kappa Opioid Receptor Selective Agonist (+)-5R,7S,8S-N-Methyl-N-[7-(1-pyrrolidinyl)-1-oxospiro[4,5]dec-8-yl]benzeneacetamide (U69,593) Synthesis. 2008: 943-947 |