Leroy B. Townsend, Ph.D.

Affiliations: 
1965-1978 University of Utah, Salt Lake City, UT 
 1979-2000 University of Michigan, Ann Arbor, Ann Arbor, MI 
Website:
http://um2017.org/faculty-history/faculty/leroy-townsend/memoir
Google:
"Leroy Townsend"
Bio:

ACS Medicinal Chemistry Hall of Fame, 1993

Cross-listing: Chemistry Tree

Parents

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Roland K. Robins grad student 1965 Arizona State (Chemistry Tree)
 (The synthesis of 1 - and 3 - methylpurines and a reinvestigation on the structural assignment of certain related purine nucleosides)

Children

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Christopher McGinley research assistant 1999 University of Michigan (Chemistry Tree)
Ji-Wang Chern grad student National Taiwan University (Chemistry Tree)
David A. Berry grad student 1988 University of Michigan (Chemistry Tree)
Tun-Cheng Chien grad student 2004 University of Michigan (Chemistry Tree)
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Publications

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Dittmer A, Woskobojnik I, Adfeldt R, et al. (2016) Tetrahalogenated benzimidazole D-ribonucleosides are active against rat cytomegalovirus. Antiviral Research
Prichard MN, Frederick SL, Daily S, et al. (2011) Benzimidazole analogs inhibit human herpesvirus 6. Antimicrobial Agents and Chemotherapy. 55: 2442-5
Frederick S, Daily S, Borysko K, et al. (2010) Structure–Activity Relationships of d- and L-analogs of Maribavir and 1-Beta-d-ribofuranosyl-2-bromo-5,6-dichlorobenzimidazole (bdcrb) Against Human Herpesvirus 6 Antiviral Research. 86: A54
CHENG CS, HOOPS GC, EARL RA, et al. (2010) ChemInform Abstract: Synthesis of Pyrrolo(2,3-d)pyrimidines that are Structurally Related to Methylated Guanosines from tRNA and the Nucleoside Q Analogues, PreQ0 and PreQ1. Cheminform. 28: no-no
GUDMUNDSSON KS, DRACH JC, WOTRING LL, et al. (2010) ChemInform Abstract: Synthesis and Antiviral Activity of Certain 5′-Modified Analogues of 2, 5,6-Trichloro-1-(β-D-ribofuranosyl)benzimidazole (TCRB). Cheminform. 28: no-no
SALLAM MAE, TOWNSEND LB, BUTLER W. (2010) ChemInform Abstract: Synthesis of 4-(2,5-Anhydro-D-galacto-pentitol-1-yl)-2-phenyl-2H-1,2,3- triazole, a homo-C-Nucleoside Analogue. Cheminform. 26: no-no
Hwang JS, Schilf R, Drach JC, et al. (2009) Susceptibilities of human cytomegalovirus clinical isolates and other herpesviruses to new acetylated, tetrahalogenated benzimidazole D-ribonucleosides. Antimicrobial Agents and Chemotherapy. 53: 5095-101
Prichard M, Frederick S, Daily S, et al. (2009) l-Analogs of 1-Beta-d-Ribofuranosyl-2-Bromo-5,6-Dichlorobenzimidazole (BDCRB) Inhibit Human Herpesvirus-6 Replication Antiviral Research. 82: A51
Chien TC, Drach JC, Townsend LB. (2008) Design and synthesis of 1-(beta-D-ribofuranosyl)imidazo[4,5-c]pyrazoles as 5:5 bicyclic analogs of purine nucleosides. Nucleic Acids Symposium Series (2004). 593-4
Hwang JS, Kregler O, Schilf R, et al. (2007) Identification of acetylated, tetrahalogenated benzimidazole D-ribonucleosides with enhanced activity against human cytomegalovirus. Journal of Virology. 81: 11604-11
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