Mark R. Denison

Vanderbilt University, Nashville, TN 
"Mark Denison"


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Anne G. Bost grad student 2000 Vanderbilt
Amy C. Sims grad student 2001 Vanderbilt
Erik Prentice grad student 2004 Vanderbilt
Sarah B. McDonald grad student 2005 Vanderbilt
Rachel L. Graham grad student 2006 Vanderbilt
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Gribble J, Stevens LJ, Agostini ML, et al. (2021) The coronavirus proofreading exoribonuclease mediates extensive viral recombination. Plos Pathogens. 17: e1009226
Corbett KS, Edwards DK, Leist SR, et al. (2020) SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness. Nature
Pruijssers AJ, George AS, Schäfer A, et al. (2020) Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice. Cell Reports. 107940
Corbett KS, Edwards D, Leist SR, et al. (2020) SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness. Biorxiv : the Preprint Server For Biology
Pruijssers AJ, George AS, Schäfer A, et al. (2020) Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice. Biorxiv : the Preprint Server For Biology
Sheahan TP, Sims AC, Zhou S, et al. (2020) An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Science Translational Medicine
Sheahan TP, Sims AC, Leist SR, et al. (2020) Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV. Nature Communications. 11: 222
Agostini ML, Pruijssers AJ, Chappell JD, et al. (2019) Small molecule antiviral β-D--hydroxycytidine inhibits a proofreading-intact coronavirus with a high genetic barrier to resistance. Journal of Virology
Graepel KW, Agostini ML, Lu X, et al. (2019) Fitness barriers limit reversion of a proofreading-deficient coronavirus. Journal of Virology
Brown AJ, Won JJ, Graham RL, et al. (2019) Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase. Antiviral Research. 104541
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