Jessica A. Flynn, Ph.D.

Affiliations: 
2005 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Microbiology
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"Jessica Flynn"

Parents

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Alice P. W. Telesnitsky grad student 2005 University of Michigan
 (Retroviral genomic RNA dimer partner selection.)
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Publications

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Flynn J, Cox K, Touch S, et al. (2019) 2729. mRNA Vaccines Encoding Conserved Influenza Antigens Induce Robust and Durable Immunity in Rhesus Macaques Open Forum Infectious Diseases. 6
Najar TA, Kar U, Flynn JA, et al. (2018) Isolation of an in vitro affinity-matured, thermostable "Headless" HA stem fragment that binds broadly neutralizing antibodies with high affinity. Biochemistry
Kesavardhana S, Das R, Citron M, et al. (2016) Structure based design of cyclically permuted HIV-1 gp120 trimers that elicit neutralizing antibodies. The Journal of Biological Chemistry
Flynn JA, Durr E, Swoyer R, et al. (2016) Stability Characterization of a Vaccine Antigen Based on the Respiratory Syncytial Virus Fusion Glycoprotein. Plos One. 11: e0164789
Mallajosyula VV, Citron M, Ferrara F, et al. (2015) Hemagglutinin Sequence Conservation Guided Stem Immunogen Design from Influenza A H3 Subtype. Frontiers in Immunology. 6: 329
Mallajosyula VV, Citron M, Ferrara F, et al. (2014) Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection. Proceedings of the National Academy of Sciences of the United States of America. 111: E2514-23
Awasthi S, Balliet JW, Flynn JA, et al. (2014) Protection provided by a herpes simplex virus 2 (HSV-2) glycoprotein C and D subunit antigen vaccine against genital HSV-2 infection in HSV-1-seropositive guinea pigs. Journal of Virology. 88: 2000-10
Awasthi S, Zumbrun EE, Si H, et al. (2012) Live attenuated herpes simplex virus 2 glycoprotein E deletion mutant as a vaccine candidate defective in neuronal spread. Journal of Virology. 86: 4586-98
Gomez R, Jolly SJ, Williams T, et al. (2011) Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase. Journal of Medicinal Chemistry. 54: 7920-33
Awasthi S, Lubinski JM, Shaw CE, et al. (2011) Immunization with a vaccine combining herpes simplex virus 2 (HSV-2) glycoprotein C (gC) and gD subunits improves the protection of dorsal root ganglia in mice and reduces the frequency of recurrent vaginal shedding of HSV-2 DNA in guinea pigs compared to immunization with gD alone. Journal of Virology. 85: 10472-86
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