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Diana M. Downs

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
Microbiology Biology
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Parents

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John Roger Roth grad student 1987 UC Davis

Children

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Julie L. Zilles grad student 1999 UW Madison
Aileen A. Rubio grad student 2001 UW Madison
Jeffrey A. Gralnick grad student 2003 UW Madison
Elizabeth C. Skovran grad student 2005 UW Madison
Alma I. Ramos-Solis grad student 2006 UW Madison
George E. Schmitz grad student 2006 UW Madison
Beth A. Browne grad student 2008 UW Madison
Michael P. Thorgersen grad student 2008 UW Madison
Norma C. Martinez Gomez grad student 2009 UW Madison
Melissa R. Christopherson grad student 2011 UW Madison
Mark J. Koenigsknecht grad student 2011 UW Madison
Jennifer A. Silverman grad student 2012 UW Madison
Jannell V. Bazurto grad student 2013 UW Madison
Jeffrey M. Flynn grad student 2013 UW Madison

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Publications

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Ezekiel KS, Downs DM. (2024) Purine limitation prevents the exogenous pyridoxal 5'-phosphate accumulation of mutants. Microbiology Spectrum. e0207524
Fulton RL, Sawyer BR, Downs DM. (2024) RidA proteins contribute to fitness of and by reducing 2AA stress and moderating flux to isoleucine biosynthesis. Microbial Cell (Graz, Austria). 11: 339-352
Shen W, Downs DM. (2024) Tetrahydrofolate levels influence 2-aminoacrylate stress in . Journal of Bacteriology. 206: e0004224
Fulton RL, Downs DM. (2023) Modulators of a robust and efficient metabolism: Perspective and insights from the Rid superfamily of proteins. Advances in Microbial Physiology. 83: 117-179
Fulton RL, Downs DM. (2022) DadY (PA5303) is required for fitness of when growth is dependent on alanine catabolism. Microbial Cell (Graz, Austria). 9: 190-201
Fulton RL, Irons J, Downs DM. (2022) The Cysteine Desulfurase IscS Is a Significant Target of 2-Aminoacrylate Damage in Pseudomonas aeruginosa. Mbio. e0107122
Shen W, Borchert AJ, Downs DM. (2022) 2-Aminoacrylate stress damages diverse PLP-dependent enzymes in vivo. The Journal of Biological Chemistry. 298: 101970
Vu HN, Downs DM. (2022) Genetic analysis using vitamin B antagonist 4-deoxypyridoxine uncovers a connection between pyridoxal 5'-phosphate and coenzyme A metabolism in . Journal of Bacteriology. jb0060721
Ito T, Ogawa H, Hemmi H, et al. (2022) Mechanism of pyridoxine 5'-phosphate accumulation in PLPBP protein-deficiency. Journal of Bacteriology. JB0052121
Paxhia MD, Downs DM. (2021) Pyridoxal and α-ketoglutarate independently improve function of Thi5 in the metabolic network of . Journal of Bacteriology. JB0045021
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