Doris L. LaRock, Ph.D.
Affiliations: | 2012 | Microbiology | University of Washington, Seattle, Seattle, WA |
Area:
Microbiology Biology, Molecular BiologyGoogle:
"Doris LaRock"Parents
Sign in to add mentor| Samuel I. Miller | grad student | 2012 | University of Washington | |
| (Activation of the Salmonella enterica serovar Typhimurium translocated glycerophospholipid:cholesterol acyltransferase SseJ by the small GTPase RhoA.) | ||||
| Victor Nizet | post-doc | 2014-2017 | UCSD | |
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Publications
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| LaRock DL, LaRock CN. (2023) Assessing Interleukin-1β Activation During Pyroptosis. Methods in Molecular Biology (Clifton, N.J.). 2641: 163-169 |
| Johnson AF, Sands JS, Trivedi KM, et al. (2023) Constitutive secretion of pro-IL-18 allows keratinocytes to initiate inflammation during bacterial infection. Plos Pathogens. 19: e1011321 |
| Everett MJ, Davies DT, Leiris S, et al. (2023) Chemical Optimization of Selective LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models. Acs Infectious Diseases |
| LaRock DL, Johnson AF, Wilde S, et al. (2022) Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes. Nature. 605: 527-531 |
| Atashgah RB, Ghasemi A, Raoufi M, et al. (2021) Restoring Endogenous Repair Mechanisms to Heal Chronic Wounds with a Multifunctional Wound Dressing. Molecular Pharmaceutics |
| Sun J, LaRock DL, Skowronski EA, et al. (2020) The Pseudomonas aeruginosa protease LasB directly activates IL-1β. Ebiomedicine. 60: 102984 |
| LaRock DL, Russell R, Johnson AF, et al. (2020) Group A Streptococcus Infection of the Nasopharynx Requires Proinflammatory Signaling Through the Interleukin-1 Receptor. Infection and Immunity |
| LaRock DL, Sands JS, Ettouati E, et al. (2019) Inflammasome inhibition blocks cardiac glycoside cell toxicity. The Journal of Biological Chemistry |
| Munguia J, LaRock DL, Tsunemoto H, et al. (2017) The Mla pathway is critical for Pseudomonas aeruginosa resistance to outer membrane permeabilization and host innate immune clearance. Journal of Molecular Medicine (Berlin, Germany) |
| LaRock CN, Todd J, LaRock DL, et al. (2016) IL-1β is an innate immune sensor of microbial proteolysis. Science Immunology. 1: eaah3539 |