Nadia V. Giannakopoulos, Ph.D.

Affiliations: 
2009 Washington University, Saint Louis, St. Louis, MO 
Area:
Immunology, Microbiology Biology
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"Nadia Giannakopoulos"

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Herbert W. Virgin, IV grad student 2009 Washington University
 (ISG15 protein conjugation has anti-viral function that is targeted by a viral immune evasion protease.)
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Publications

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Giannakopoulos NV, Arutyunova E, Lai C, et al. (2009) ISG15 Arg151 and the ISG15-conjugating enzyme UbE1L are important for innate immune control of Sindbis virus. Journal of Virology. 83: 1602-10
Frias-Staheli N, Giannakopoulos NV, Kikkert M, et al. (2007) Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses. Cell Host & Microbe. 2: 404-16
Lenschow DJ, Lai C, Frias-Staheli N, et al. (2007) IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proceedings of the National Academy of Sciences of the United States of America. 104: 1371-6
Lenschow DJ, Giannakopoulos NV, Gunn LJ, et al. (2005) Identification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo. Journal of Virology. 79: 13974-83
Giannakopoulos NV, Luo JK, Papov V, et al. (2005) Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. Biochemical and Biophysical Research Communications. 336: 496-506
Kim KI, Giannakopoulos NV, Virgin HW, et al. (2004) Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation. Molecular and Cellular Biology. 24: 9592-600
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