Douglas J. Botkin, Ph.D.

2009 The University of Texas Graduate School of Biomedical Sciences at Houston 
Microbiology Biology, Molecular Biology, Genetics
"Douglas Botkin"


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Steven J. Norris grad student 2009 The University of Texas Graduate School of Biomedical Sciences at Houston
 (Identification and characterization of virulence determinants in the Lyme disease spirochete Borrelia burgdorferi.)
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Botkin DJ, Galli L, Sankarapani V, et al. (2012) Development of a multiplex PCR assay for detection of Shiga toxin-producing Escherichia coli, enterohemorrhagic E. coli, and enteropathogenic E. coli strains. Frontiers in Cellular and Infection Microbiology. 2: 8
Del Canto F, Botkin DJ, Valenzuela P, et al. (2012) Identification of Coli Surface Antigen 23, a novel adhesin of enterotoxigenic Escherichia coli. Infection and Immunity. 80: 2791-801
Farfan MJ, Cantero L, Vidal R, et al. (2011) Long polar fimbriae of enterohemorrhagic Escherichia coli O157:H7 bind to extracellular matrix proteins. Infection and Immunity. 79: 3744-50
Liu J, Lin T, Botkin DJ, et al. (2009) Intact flagellar motor of Borrelia burgdorferi revealed by cryo-electron tomography: evidence for stator ring curvature and rotor/C-ring assembly flexion. Journal of Bacteriology. 191: 5026-36
Coutte L, Botkin DJ, Gao L, et al. (2009) Detailed analysis of sequence changes occurring during vlsE antigenic variation in the mouse model of Borrelia burgdorferi infection. Plos Pathogens. 5: e1000293
Botkin DJ, Abbott AN, Stewart PE, et al. (2006) Identification of potential virulence determinants by Himar1 transposition of infectious Borrelia burgdorferi B31. Infection and Immunity. 74: 6690-9
Wang D, Botkin DJ, Norris SJ. (2003) Characterization of the vls antigenic variation loci of the Lyme disease spirochaetes Borrelia garinii Ip90 and Borrelia afzelii ACAI. Molecular Microbiology. 47: 1407-17
Williams DL, Asahi H, Botkin DJ, et al. (2001) Schistosome infection stimulates host CD4+ T helper cell and B-cell responses against a novel egg antigen, thioredoxin peroxidase Infection and Immunity. 69: 1134-1141
Kwatia MA, Botkin DJ, Williams DL. (2000) Molecular and enzymatic characterization of Schistosoma mansoni thioredoxin peroxidase Journal of Parasitology. 86: 908-915
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