Timothy S. Fisher, Ph.D.
Affiliations: | 2002 | Yeshiva University, New York, NY, United States |
Area:
Molecular Biology, Biochemistry, Microbiology BiologyGoogle:
"Timothy Fisher"Parents
Sign in to add mentorVinayaka R. Prasad | grad student | 2002 | Yeshiva University | |
(Human immunodeficiency virus type 1 reverse transcriptase: The role of template -primer interactions in polymerase function.) |
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Publications
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Dash C, Fisher TS, Prasad VR, et al. (2006) Examining interactions of HIV-1 reverse transcriptase with single-stranded template nucleotides by nucleoside analog interference. The Journal of Biological Chemistry. 281: 27873-81 |
Fisher TS, Joshi P, Prasad VR. (2005) HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors. Aids Research and Therapy. 2: 8 |
Joshi PJ, Fisher TS, Prasad VR. (2003) Anti-HIV inhibitors based on nucleic acids: emergence of aptamers as potent antivirals. Current Drug Targets. Infectious Disorders. 3: 383-400 |
Fisher TS, Darden T, Prasad VR. (2003) Mutations proximal to the minor groove-binding track of human immunodeficiency virus type 1 reverse transcriptase differentially affect utilization of RNA versus DNA as template. Journal of Virology. 77: 5837-45 |
Fisher TS, Darden T, Prasad VR. (2003) Substitutions at Phe61 in the beta3-beta4 hairpin of HIV-1 reverse transcriptase reveal a role for the Fingers subdomain in strand displacement DNA synthesis. Journal of Molecular Biology. 325: 443-59 |
Fisher TS, Prasad VR. (2002) Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase. The Journal of Biological Chemistry. 277: 22345-52 |
Fisher TS, Joshi P, Prasad VR. (2002) Mutations that confer resistance to template-analog inhibitors of human immunodeficiency virus (HIV) type 1 reverse transcriptase lead to severe defects in HIV replication. Journal of Virology. 76: 4068-72 |