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David E. Briles

Affiliations: 
University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Microbiology Biology
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Parents

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Richard M. Krause grad student 1973 Rockefeller

Children

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Randall H. Harris grad student 2000 UAB
Priya Balachandran grad student 2001 UAB
Hazeline Roche grad student 2002 UAB
Jason W. Johnston grad student 2003 UAB
Mamie T. Coats grad student 2005 UAB
Shaper Mirza grad student 2006 UAB
Dorothy B. Payne grad student 2007 UAB
Calvin C. Daniels grad student 2010 UAB
Christina M. Croney grad student 2013 UAB
Kristopher R. Genschmer grad student 2013 UAB
Janet Yother post-doc UAB

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Publications

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Wang J, An H, Ding M, et al. (2023) Liver macrophages and sinusoidal endothelial cells execute vaccine-elicited capture of invasive bacteria. Science Translational Medicine. 15: eade0054
Lane JR, Tata M, Briles DE, et al. (2022) A Jack of All Trades: The Role of Pneumococcal Surface Protein A in the Pathogenesis of . Frontiers in Cellular and Infection Microbiology. 12: 826264
Park SS, Gonzalez-Juarbe N, Riegler AN, et al. (2021) Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza. Cell Reports. 35: 109267
Nakahashi-Ouchida R, Uchida Y, Yuki Y, et al. (2021) A nanogel-based trivalent PspA nasal vaccine protects macaques from intratracheal challenge with pneumococci. Vaccine
Park SS, Gonzalez-Juarbe N, Martínez E, et al. (2021) Streptococcus pneumoniae Binds to Host Lactate Dehydrogenase via PspA and PspC To Enhance Virulence. Mbio. 12
Yuki Y, Uchida Y, Sawada SI, et al. (2021) Characterization and Specification of a Trivalent Protein-Based Pneumococcal Vaccine Formulation Using an Adjuvant-Free Nanogel Nasal Delivery System. Molecular Pharmaceutics
Takeda S, Kono M, Sugita G, et al. (2021) Pneumococcal capsular phase shift is associated with invasion into cell-to-cell junctions and is inhibited by macrolides. Microbial Pathogenesis. 104787
Mukerji R, Briles DE. (2020) New Strategy Is Needed to Prevent Pneumococcal Meningitis. The Pediatric Infectious Disease Journal
Briles DE, Paton JC, Mukerji R, et al. (2020) Pneumococcal Vaccines. Microbiology Spectrum. 7
Keech CA, Morrison R, Anderson P, et al. (2019) A Phase 1 Randomized, Placebo-controlled, Observer-blinded Trial to Evaluate the Safety and Immunogenicity of Inactivated Streptococcus pneumoniae Whole-cell Vaccine in Adults. The Pediatric Infectious Disease Journal
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