Brian R. Lane, Ph.D.

Affiliations: 
2002 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Immunology, Microbiology Biology
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"Brian Lane"

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David M. Markovitz grad student 2002 University of Michigan
 (The involvement of the chemokines IL-8 and GRO-alpha in the pathogenesis of AIDS -associated Kaposi's sarcoma.)
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Publications

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Lane BR, King SR, Bock PJ, et al. (2003) The C-X-C chemokine IP-10 stimulates HIV-1 replication. Virology. 307: 122-34
Faulkner NE, Lane BR, Bock PJ, et al. (2003) Protein phosphatase 2A enhances activation of human immunodeficiency virus type 1 by phorbol myristate acetate. Journal of Virology. 77: 2276-81
Lane BR, Liu J, Bock PJ, et al. (2002) Interleukin-8 and growth-regulated oncogene alpha mediate angiogenesis in Kaposi's sarcoma. Journal of Virology. 76: 11570-83
Hayes MM, Lane BR, King SR, et al. (2002) Prostaglandin E(2) inhibits replication of HIV-1 in macrophages through activation of protein kinase A. Cellular Immunology. 215: 61-71
Hayes MM, Lane BR, King SR, et al. (2002) Peroxisome proliferator-activated receptor gamma agonists inhibit HIV-1 replication in macrophages by transcriptional and post-transcriptional effects. The Journal of Biological Chemistry. 277: 16913-9
Lane BR, Lore K, Bock PJ, et al. (2001) Interleukin-8 stimulates human immunodeficiency virus type 1 replication and is a potential new target for antiretroviral therapy. Journal of Virology. 75: 8195-202
Lane BR, Strieter RM, Coffey MJ, et al. (2001) Human immunodeficiency virus type 1 (HIV-1)-induced GRO-alpha production stimulates HIV-1 replication in macrophages and T lymphocytes. Journal of Virology. 75: 5812-22
Browning CM, Smith MJ, Clark NM, et al. (2001) Human GLI-2 is a tat activation response element-independent Tat cofactor. Journal of Virology. 75: 2314-23
Smith MJ, Gitlin SD, Browning CM, et al. (2001) GLI-2 modulates retroviral gene expression. Journal of Virology. 75: 2301-13
Lane BR, Markovitz DM, Woodford NL, et al. (1999) TNF-alpha inhibits HIV-1 replication in peripheral blood monocytes and alveolar macrophages by inducing the production of RANTES and decreasing C-C chemokine receptor 5 (CCR5) expression. Journal of Immunology (Baltimore, Md. : 1950). 163: 3653-61
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