Roddy S. O'Connor, Ph.D.
Affiliations: | 2007 | Emory University, Atlanta, GA |
Area:
Cell Biology, Physiology Biology, Molecular BiologyGoogle:
"Roddy O'Connor"Parents
Sign in to add mentorGrace K. Pavlath | grad student | 2007 | Emory | |
(The NFAT5 signaling pathway and skeletal muscle myogenesis.) |
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Publications
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Roselle C, Horikawa I, Chen L, et al. (2024) Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Δ133p53α. Proceedings of the National Academy of Sciences of the United States of America. 121: e2317735121 |
Akbari B, Hosseini Z, Shahabinejad P, et al. (2022) Metabolic and epigenetic orchestration of (CAR) T cell fate and function. Cancer Letters. 550: 215948 |
Ghassemi S, Durgin JS, Nunez-Cruz S, et al. (2022) Rapid manufacturing of non-activated potent CAR T cells. Nature Biomedical Engineering. 6: 118-128 |
Durgin JS, Thokala R, Johnson L, et al. (2021) Enhancing CAR T Function with the Engineered Secretion of C. Perfringens Neuraminidase. Molecular Therapy : the Journal of the American Society of Gene Therapy |
Garcia-Canaveras JC, Heo D, Trefely S, et al. (2021) CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production. Cells. 10 |
Tu VY, Ayari A, O'Connor RS. (2021) Beyond the Lactate Paradox: How Lactate and Acidity Impact T Cell Therapies against Cancer. Antibodies (Basel, Switzerland). 10 |
Tu VY, Ayari A, O'Connor RS. (2021) Beyond the Lactate Paradox: How Lactate and Acidity Impact T Cell Therapies against Cancer. Antibodies (Basel, Switzerland). 10 |
Das RK, O'Connor RS, Grupp SA, et al. (2020) Lingering effects of chemotherapy on mature T cells impair proliferation. Blood Advances. 4: 4653-4664 |
Ghassemi S, Martinez-Becerra FJ, Master AM, et al. (2020) Enhancing Chimeric Antigen Receptor T Cell Anti-tumor Function through Advanced Media Design. Molecular Therapy. Methods & Clinical Development. 18: 595-606 |
Philipson BI, O'Connor RS, May MJ, et al. (2020) 4-1BB costimulation promotes CAR T cell survival through noncanonical NF-κB signaling. Science Signaling. 13 |