Hesham F. Nawar, Ph.D.

Affiliations: 
2006 State University of New York, Buffalo, Buffalo, NY, United States 
Area:
Immunology, Pathology
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"Hesham Nawar"

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Terry D. Connell grad student 2006 SUNY Buffalo
 (Mucosal adjuvant properties of mutant LT-IIa and LT-IIb enterotoxins that exhibit altered ganglioside -binding activities.)
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Publications

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Gopal R, Rangel-Moreno J, Slight S, et al. (2013) Interleukin-17-dependent CXCL13 mediates mucosal vaccine-induced immunity against tuberculosis. Mucosal Immunology. 6: 972-84
Berenson CS, Nawar HF, Kruzel RL, et al. (2013) Ganglioside-binding specificities of E. coli enterotoxin LT-IIc: Importance of long-chain fatty acyl ceramide Glycobiology. 23: 23-31
Cody V, Pace J, Nawar HF, et al. (2012) Structure-activity correlations of variant forms of the B pentamer of Escherichia coli type II heat-labile enterotoxin LT-IIb with Toll-like receptor 2 binding. Acta Crystallographica. Section D, Biological Crystallography. 68: 1604-12
Nawar HF, Greene CJ, Lee CH, et al. (2011) LT-IIc, a new member of the type II heat-labile enterotoxin family, exhibits potent immunomodulatory properties that are different from those induced by LT-IIa or LT-IIb Vaccine. 29: 721-727
Nawar HF, King-Lyons ND, Hu JC, et al. (2010) LT-IIc, a new member of the type II heat-labile enterotoxin family encoded by an Escherichia coli strain obtained from a nonmammalian host. Infection and Immunity. 78: 4705-13
Nawar HF, Berenson CS, Hajishengallis G, et al. (2010) Binding to gangliosides containing N-acetylneuraminic acid is sufficient to mediate the immunomodulatory properties of the nontoxic mucosal adjuvant LT-IIb(T13I) Clinical and Vaccine Immunology. 17: 969-978
Lee CH, Nawar HF, Mandell L, et al. (2010) Enhanced antigen uptake by dendritic cells induced by the B pentamer of the type II heat-labile enterotoxin LT-IIa requires engagement of TLR2 Vaccine. 28: 3696-3705
Berenson CS, Nawar HF, Yohe HC, et al. (2010) Mammalian cell ganglioside-binding specificities of E. coli enterotoxins LT-IIb and variant LT-IIb(T13I). Glycobiology. 20: 41-54
Liang S, Hosur KB, Nawar HF, et al. (2009) In vivo and in vitro adjuvant activities of the B subunit of Type IIb heat-labile enterotoxin (LT-IIb-B5) from Escherichia coli. Vaccine. 27: 4302-8
Taube S, Perry JW, Yetming K, et al. (2009) Ganglioside-linked terminal sialic acid moieties on murine macrophages function as attachment receptors for murine noroviruses. Journal of Virology. 83: 4092-101
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