Donald D. Muccio

Affiliations: 
University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Biochemistry, Microbiology Biology
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"Donald Muccio"

Children

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Yi-Chien Lee grad student 2001 UAB
Kimberly K. Vines grad student 2001 UAB
Brandon S. Pybus grad student 2002 UAB
Gang Xia grad student 2010 UAB
Bryan D. Cox grad student 2012 UAB
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Publications

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Kolesar JM, Andrews S, Green H, et al. (2019) A Randomized, Placebo-Controlled, Double-Blind, Dose Escalation, Single Dose and Steady State Pharmacokinetics Study of 9cUAB30 in Healthy Volunteers. Cancer Prevention Research (Philadelphia, Pa.)
Williams AP, Waters AM, Stewart JE, et al. (2018) A novel retinoid X receptor agonist, UAB30, inhibits rhabdomyosarcoma cells in vitro. The Journal of Surgical Research. 228: 54-62
Chou CF, Hsieh YH, Grubbs CJ, et al. (2018) The retinoid X receptor agonist, 9-cis UAB30, inhibits cutaneous T-cell lymphoma proliferation through the SKP2-p27kip1 axis. Journal of Dermatological Science
Muccio DD, Atigadda VR, Brouillette WJ, et al. (2016) Translation of a Tissue-Selective Rexinoid, UAB30, to the Clinic for Breast Cancer Prevention. Current Topics in Medicinal Chemistry
Wu L, Chaudhary SC, Atigadda VR, et al. (2016) Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis. Plos One. 11: e0153556
Waters AM, Stewart JE, Atigadda VR, et al. (2016) Pre-Clinical Evaluation of UAB30 in Pediatric Renal and Hepatic Malignancies. Molecular Cancer Therapeutics
Atigadda VR, Xia G, Deshpande A, et al. (2015) Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers. Journal of Medicinal Chemistry. 58: 7763-74
Waters AM, Stewart JE, Atigadda VR, et al. (2015) Preclinical Evaluation of a Novel RXR Agonist for the Treatment of Neuroblastoma. Molecular Cancer Therapeutics
Atigadda VR, Xia G, Desphande A, et al. (2014) Methyl substitution of a rexinoid agonist improves potency and reveals site of lipid toxicity. Journal of Medicinal Chemistry. 57: 5370-80
Desphande A, Xia G, Boerma LJ, et al. (2014) Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention. Bioorganic & Medicinal Chemistry. 22: 178-85
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