Nathan C. Simon, Ph.D.

Affiliations: 
2014 Medical College of Wisconsin, Milwaukee, WI, United States 
Area:
Microbiology Biology, Genetics, General Biology
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"Nathan Simon"

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Joseph Barbieri grad student 2014 Medical College of Wisconsin
 (Certhrax: A unique ADP-ribosylating toxin with novel substrate specificity.)
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Publications

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Simon NC, Aktories K, Barbieri JT. (2014) Novel bacterial ADP-ribosylating toxins: structure and function. Nature Reviews. Microbiology. 12: 599-611
Simon NC, Barbieri JT. (2014) Bacillus cereus Certhrax ADP-ribosylates vinculin to disrupt focal adhesion complexes and cell adhesion. The Journal of Biological Chemistry. 289: 10650-9
Schuld NJ, Vervacke JS, Lorimer EL, et al. (2014) The chaperone protein SmgGDS interacts with small GTPases entering the prenylation pathway by recognizing the last amino acid in the CAAX motif. The Journal of Biological Chemistry. 289: 6862-76
Simon NC, Barbieri JT. (2014) Exoenzyme S ADP-ribosylates Rab5 effector sites to uncouple intracellular trafficking. Infection and Immunity. 82: 21-8
Simon NC, Vergis JM, Ebrahimi AV, et al. (2013) Host cell cytotoxicity and cytoskeleton disruption by CerADPr, an ADP-ribosyltransferase of Bacillus cereus G9241. Biochemistry. 52: 2309-18
Hritonenko V, Mun JJ, Tam C, et al. (2011) Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence. Microbial Pathogenesis. 51: 305-12
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