Shailja Pathania, Ph.D.

Affiliations: 
2002 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Molecular Biology, Microbiology Biology
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"Shailja Pathania"

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Rasika M. Harshey grad student 2002 UT Austin
 (Path of DNA within Mu transpososomes: Order, dynamics and topology of Mu end-enhancer interactions.)
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Publications

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Hatchi E, Skourti-Stathaki K, Ventz S, et al. (2015) BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair. Molecular Cell. 57: 636-47
Pathania S, Bade S, Le Guillou M, et al. (2014) BRCA1 haploinsufficiency for replication stress suppression in primary cells. Nature Communications. 5: 5496
Dimitrov SD, Lu D, Naetar N, et al. (2013) Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycle. Genes & Development. 27: 2274-91
Pathania S, Nguyen J, Hill SJ, et al. (2011) BRCA1 is required for postreplication repair after UV-induced DNA damage. Molecular Cell. 44: 235-51
Johnson N, Cai D, Kennedy RD, et al. (2009) Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage. Molecular Cell. 35: 327-39
Greenberg RA, Sobhian B, Pathania S, et al. (2006) Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes & Development. 20: 34-46
Yin Z, Jayaram M, Pathania S, et al. (2005) The Mu transposase interwraps distant DNA sites within a functional transpososome in the absence of DNA supercoiling. The Journal of Biological Chemistry. 280: 6149-56
Au TK, Pathania S, Harshey RM. (2004) True reversal of Mu integration. The Embo Journal. 23: 3408-20
Pathania S, Jayaram M, Harshey RM. (2003) A unique right end-enhancer complex precedes synapsis of Mu ends: the enhancer is sequestered within the transpososome throughout transposition. The Embo Journal. 22: 3725-36
Grainge I, Pathania S, Vologodskii A, et al. (2002) Symmetric DNA sites are functionally asymmetric within Flp and Cre site-specific DNA recombination synapses. Journal of Molecular Biology. 320: 515-27
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