Harvey Rubin
Affiliations: | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Biochemistry, Molecular Biology, Microbiology BiologyGoogle:
"Harvey Rubin"Children
Sign in to add traineeDavid H. Avarbock | grad student | 2000 | Penn |
Andrew B. Avarbock | grad student | 2005 | Penn |
Michael H. Buckstein | grad student | 2006 | Penn |
Jamaine S. Davis | grad student | 2007 | Penn |
Marcin Imielinski | grad student | 2007 | Penn |
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Publications
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Dutta NK, Klinkenberg LG, Vazquez MJ, et al. (2019) Inhibiting the stringent response blocks entry into quiescence and reduces persistence. Science Advances. 5: eaav2104 |
Harbut MB, Liu R, Yang B, et al. (2018) Small molecules targeting Mycobacterium tuberculosis type II NADH dehydrogenase with antimycobacterial activity. Angewandte Chemie (International Ed. in English) |
Tantry SJ, Markad SD, Shinde V, et al. (2017) Discovery of Imidazo[1,2-a]pyridine ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis. Journal of Medicinal Chemistry |
Chuang YM, Dutta NK, Hung CF, et al. (2016) The stringent response factors PPX1 and PPK2 play an important role in Mycobacterium tuberculosis metabolism, biofilm formation, and sensitivity to isoniazid in vivo. Antimicrobial Agents and Chemotherapy |
Tantry SJ, Shinde V, Balakrishnan G, et al. (2016) Scaffold morphing leading to evolution of 2,4-diaminoquinolines and aminopyrazolopyrimidines as inhibitors of the ATP synthesis pathway Medchemcomm. 7: 1022-1032 |
Chuang YM, Bandyopadhyay N, Rifat D, et al. (2015) Deficiency of the novel exopolyphosphatase Rv1026/PPX2 leads to metabolic downshift and altered cell wall permeability in Mycobacterium tuberculosis. Mbio. 6: e02428 |
Rubin H, Selwood T, Yano T, et al. (2015) Acinetobacter baumannii OxPhos inhibitors as selective anti-infective agents. Bioorganic & Medicinal Chemistry Letters. 25: 378-83 |
Schurig-Briccio LA, Yano T, Rubin H, et al. (2014) Characterization of the type 2 NADH:menaquinone oxidoreductases from Staphylococcus aureus and the bactericidal action of phenothiazines. Biochimica Et Biophysica Acta. 1837: 954-63 |
Yano T, Rahimian M, Aneja KK, et al. (2014) Mycobacterium tuberculosis type II NADH-menaquinone oxidoreductase catalyzes electron transfer through a two-site ping-pong mechanism and has two quinone-binding sites. Biochemistry. 53: 1179-90 |
Thayil SM, Morrison N, Schechter N, et al. (2011) The role of the novel exopolyphosphatase MT0516 in Mycobacterium tuberculosis drug tolerance and persistence. Plos One. 6: e28076 |