Lawrence F. Povirk
Affiliations: | Virginia Commonwealth University, Richmond, VA, United States |
Area:
Oncology, Microbiology BiologyGoogle:
"Lawrence Povirk"Parents
Sign in to add mentor| Robert Blair Painter | grad student | 1972-1977 | UCSF (Chemistry Tree) |
| Franklin Hutchinson | post-doc | 1977-1979 | Yale (Physics Tree) |
| Irving Hyman Goldberg | research scientist | 1982-1985 | Harvard Medical School |
Children
Sign in to add trainee| Yin Yu | grad student | 2000 | VCU |
| Kedar V. Inamdar | grad student | 2002 | VCU |
| Amy J. Hawkins | grad student | 2009 | VCU |
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Publications
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| Sule A, Golding SE, Ahmad SF, et al. (2022) ATM phosphorylates PP2A subunit A resulting in nuclear export and spatiotemporal regulation of the DNA damage response. Cellular and Molecular Life Sciences : Cmls. 79: 603 |
| Kawale AS, Akopiants K, Valerie K, et al. (2018) TDP1 suppresses mis-joining of radiomimetic DNA double-strand breaks and cooperates with Artemis to promote optimal nonhomologous end joining. Nucleic Acids Research |
| Chalasani SL, Kawale AS, Akopiants K, et al. (2018) Persistent 3'-phosphate termini and increased cytotoxicity of radiomimetic DNA double-strand breaks in cells lacking polynucleotide kinase/phosphatase despite presence of an alternative 3'-phosphatase. Dna Repair. 68: 12-24 |
| Kawale AS, Povirk LF. (2017) Tyrosyl-DNA phosphodiesterases: rescuing the genome from the risks of relaxation. Nucleic Acids Research |
| Menon V, Povirk LF. (2017) XLF/Cernunnos: An important but puzzling participant in the nonhomologous end joining DNA repair pathway. Dna Repair. 58: 29-37 |
| Menon V, Povirk LF. (2016) End-processing nucleases and phosphodiesterases: An elite supporting cast for the non-homologous end joining pathway of DNA double-strand break repair. Dna Repair. 43: 57-68 |
| Almohaini M, Chalasani SL, Bafail D, et al. (2016) Nonhomologous end joining of complex DNA double-strand breaks with proximal thymine glycol and interplay with base excision repair. Dna Repair. 41: 16-26 |
| Alotaibi M, Sharma K, Saleh T, et al. (2016) Radiosensitization by PARP Inhibition in DNA Repair Proficient and Deficient Tumor Cells: Proliferative Recovery in Senescent Cells. Radiation Research |
| Zhou L, Chen S, Zhang Y, et al. (2016) The NAE inhibitor pevonedistat interacts with the HDAC inhibitor belinostat to target AML cells by disrupting the DDR. Blood |
| Alotaibi MR, Sharma K, Saleh T, et al. (2016) Abstract 2848: Autophagy, senescence and proliferative recovery subsequent to DNA damage in radiation sensitization by PARP inhibition Cancer Research. 76: 2848-2848 |