Lancelot S. McLean, Ph.D.

Affiliations: 
2008 Loma Linda University, Loma Linda, United States 
Area:
Oncology, Genetics
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"Lancelot McLean"

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Hansel Fletcher grad student 2008 Loma Linda University
 (Oxidative stress-mediated anticancer activity of novel AhR modulators AF & 5F203.)
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Publications

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Rowland LK, Campbell PS, Mavingire N, et al. (2018) Putative tumor suppressor cytoglobin promotes aryl hydrocarbon receptor ligand-mediated triple negative breast cancer cell death. Journal of Cellular Biochemistry
McLean LS, Watkins CN, Campbell P, et al. (2015) Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells. Chemical Research in Toxicology. 28: 855-71
Rowland LK, McLean LS, Campbell P, et al. (2015) Abstract 2565: Aryl hydrocarbon receptor agonist 5F 203 induces oxidative stress triggering DNA damage and cytoglobin up-regulation in human breast cancer cells Cancer Research. 75: 2565-2565
McLean LS, Crane L, Baziard-Mouysset G, et al. (2014) Antiproliferative effect induced by novel imidazoline S43126 in PC12 cells is mediated by ROS, stress activated MAPKs and caspases. Pharmacological Reports : Pr. 66: 937-45
Brantley EJ, Thorne G, Daly D, et al. (2013) Abstract 2102: Investigational agent 5F 203 modulates apoptotic regulatory gene expression and induces lysosomal membrane permeabilization in breast cancer cells. Cancer Research. 73: 2102-2102
Brantley EJ, Watkins C, McLean L, et al. (2010) Abstract 3658: 5F 203 modulates oxidative stress, induces single-strand break formation and promotes mitochondrial membrane potential loss in sensitive breast cancer cells Cancer Research. 70: 3658-3658
McLean L, Soto U, Agama K, et al. (2008) Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cells. International Journal of Cancer. 122: 1665-74
Johnson NA, McKenzie R, McLean L, et al. (2004) 8-oxo-7,8-dihydroguanine is removed by a nucleotide excision repair-like mechanism in Porphyromonas gingivalis W83. Journal of Bacteriology. 186: 7697-703
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