Colleen M. Noviello, Ph.D.

Affiliations: 
2007 University of California, San Diego, La Jolla, CA 
Area:
Virology Biology
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"Colleen Noviello"

Parents

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John C. Guatelli grad student 2007 UCSD
 (Downregulation of MHC-I by HIV-1 Nef: Evolution after sexual transmission and mechanism of action.)
Eric Barklis post-doc OHSU
Ryan E. Hibbs research scientist UT Southwestern (Chemistry Tree)
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Publications

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Baxter L, Hopkins S, O'Connor KC, et al. (2024) Fluorescence-detection size-exclusion chromatography specifically detects autoantibodies targeting the ganglionic acetylcholine receptor in patients with autoimmune autonomic ganglionopathy. Journal of Neuroimmunology. 396: 578454
Burke SM, Avstrikova M, Noviello CM, et al. (2024) Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation. Cell. 187: 1160-1176.e21
Legesse DH, Fan C, Teng J, et al. (2023) Structural insights into opposing actions of neurosteroids on GABA receptors. Nature Communications. 14: 5091
Zhuang Y, Noviello CM, Hibbs RE, et al. (2022) Differential interactions of resting, activated, and desensitized states of the α7 nicotinic acetylcholine receptor with lipidic modulators. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208081119
Noviello CM, Kreye J, Teng J, et al. (2022) Structural mechanisms of GABA receptor autoimmune encephalitis. Cell. 185: 2469-2477.e13
Noviello CM, Gharpure A, Mukhtasimova N, et al. (2021) Structure and gating mechanism of the α7 nicotinic acetylcholine receptor. Cell
Kim JJ, Gharpure A, Teng J, et al. (2020) Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature
Rahman MM, Teng J, Worrell BT, et al. (2020) Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins. Neuron
Gharpure A, Noviello CM, Hibbs RE. (2020) Progress in nicotinic receptor structural biology. Neuropharmacology. 171: 108086
Kim JJ, Gharpure A, Teng J, et al. (2020) Cryo-EM Structure of the α1β2γ2 GabaAReceptor in a Lipidic Environment Biophysical Journal. 118: 582a-583a
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