Irina Margine, Ph.D.

Affiliations: 
2014 Microbiology Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Microbiology Biology, Virology Biology
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"Irina Margine"

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Peter Palese grad student 2014 Mount Sinai School of Medicine
 (Towards the development of a universal vaccine for influenza viruses: Induction of Broadly Protective Hemagglutinin Stalk Antibodies by Natural Infection and Novel Vaccination Strategies.)
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Publications

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Nachbagauer R, Choi A, Hirsh A, et al. (2017) Defining the antibody cross-reactome directed against the influenza virus surface glycoproteins. Nature Immunology
Tan GS, Leon PE, Albrecht RA, et al. (2016) Broadly-Reactive Neutralizing and Non-neutralizing Antibodies Directed against the H7 Influenza Virus Hemagglutinin Reveal Divergent Mechanisms of Protection. Plos Pathogens. 12: e1005578
Wohlbold TJ, Nachbagauer R, Margine I, et al. (2015) Vaccination with soluble headless hemagglutinin protects mice from challenge with divergent influenza viruses. Vaccine. 33: 3314-21
Margine I, Krammer F. (2014) Animal models for influenza viruses: implications for universal vaccine development. Pathogens (Basel, Switzerland). 3: 845-74
Krammer F, Jul-Larsen A, Margine I, et al. (2014) An H7N1 influenza virus vaccine induces broadly reactive antibody responses against H7N9 in humans. Clinical and Vaccine Immunology : Cvi. 21: 1153-63
Krammer F, Albrecht RA, Tan GS, et al. (2014) Divergent H7 immunogens offer protection from H7N9 virus challenge. Journal of Virology. 88: 3976-85
Krammer F, Margine I, Hai R, et al. (2014) H3 stalk-based chimeric hemagglutinin influenza virus constructs protect mice from H7N9 challenge. Journal of Virology. 88: 2340-3
Klausberger M, Wilde M, Palmberger D, et al. (2014) One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge. Vaccine. 32: 355-62
Hai R, Schmolke M, Leyva-Grado VH, et al. (2013) Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility. Nature Communications. 4: 2854
Margine I, Palese P, Krammer F. (2013) Expression of functional recombinant hemagglutinin and neuraminidase proteins from the novel H7N9 influenza virus using the baculovirus expression system. Journal of Visualized Experiments : Jove. e51112
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