Kris Chadee

McGill University, Montreal, QC, Canada 
Cell Biology, Pathology, Microbiology Biology
"Kris Chadee"
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Mortimer L, Moreau F, MacDonald JA, et al. (2016) NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations. Nature Immunology
Cornick S, Moreau F, Chadee K. (2016) Entamoeba histolytica Cysteine Proteinase 5 Evokes Mucin Exocytosis from Colonic Goblet Cells via αvβ3 Integrin. Plos Pathogens. 12: e1005579
Begum S, Quach J, Chadee K. (2015) Immune Evasion Mechanisms of Entamoeba histolytica: Progression to Disease. Frontiers in Microbiology. 6: 1394
Mortimer L, Moreau F, Cornick S, et al. (2015) The NLRP3 Inflammasome Is a Pathogen Sensor for Invasive Entamoeba histolytica via Activation of α5β1 Integrin at the Macrophage-Amebae Intercellular Junction. Plos Pathogens. 11: e1004887
Cobo ER, Kissoon-Singh V, Moreau F, et al. (2015) Colonic MUC2 mucin regulates the expression and antimicrobial activity of β-defensin 2 Mucosal Immunology. 8: 1360-1372
Kissoon-Singh V, Trusevych E, Chadee K. (2015) The effect of entamoeba histolytica on Muc2 mucin and intestinal permeability Amebiasis: Biology and Pathogenesis of Entamoeba. 471-486
Mortimer L, Chadee K. (2015) Innate host defenses in the gut Amebiasis: Biology and Pathogenesis of Entamoeba. 433-445
Lejeune M, Moreau F, Chadee K. (2014) Loss of EP2 receptor subtype in colonic cells compromise epithelial barrier integrity by altering claudin-4. Plos One. 9: e113270
Skappak C, Akierman S, Belga S, et al. (2014) Invasive amoebiasis: a review of Entamoeba infections highlighted with case reports. Canadian Journal of Gastroenterology & Hepatology. 28: 355-9
St-Pierre J, Chadee K. (2014) How the discovery of TNF-α has advanced gastrointestinal diseases and treatment regimes. Digestive Diseases and Sciences. 59: 712-5
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