James E. Cherwa, Ph.D.

2009 Microbiology University of Arizona, Tucson, AZ 
Virology Biology, Genetics, Microbiology Biology
"James Cherwa"


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Bentley A. Fane grad student 2009 University of Arizona
 (Characterization of scaffolding proteins altered in the ability to perform a critical conformational switch.)
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Cherwa JE, Tyson J, Bedwell GJ, et al. (2016) φX174 procapsid assembly: the effects of an inhibitory external scaffolding protein and resistant coat proteins in vitro. Journal of Virology
Li R, Cherwa JE, Prevelige PE. (2013) ϕ29 Scaffolding and connector structure-function relationship studied by trans-complementation. Virology. 444: 355-62
Cherwa JE, Organtini LJ, Ashley RE, et al. (2011) In VITRO ASSEMBLY of the øX174 procapsid from external scaffolding protein oligomers and early pentameric assembly intermediates. Journal of Molecular Biology. 412: 387-96
Cherwa JE, Fane BA. (2011) From resistance to stimulation: the evolution of a virus in the presence of a dominant lethal inhibitory scaffolding protein. Journal of Virology. 85: 6589-93
Cherwa JE, Young LN, Fane BA. (2011) Uncoupling the functions of a multifunctional protein: the isolation of a DNA pilot protein mutant that affects particle morphogenesis. Virology. 411: 9-14
Cherwa JE, Sanchez-Soria P, et al. (2009) Viral adaptation to an antiviral protein enhances the fitness level to above that of the uninhibited wild type. Journal of Virology. 83: 11746-50
Ruboyianes MV, Chen M, Dubrava MS, et al. (2009) The expression of N-terminal deletion DNA pilot proteins inhibits the early stages of phiX174 replication. Journal of Virology. 83: 9952-6
Cherwa JE, Fane BA. (2009) Complete virion assembly with scaffolding proteins altered in the ability to perform a critical conformational switch. Journal of Virology. 83: 7391-6
Cherwa JE, Uchiyama A, Fane BA. (2008) Scaffolding proteins altered in the ability to perform a conformational switch confer dominant lethal assembly defects. Journal of Virology. 82: 5774-80
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