Travis M. Wohlers, Ph.D.

Affiliations: 
2000 Emory University, Atlanta, GA 
Area:
Genetics, Molecular Biology, Pathology
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"Travis Wohlers"

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Judith L. Fridovich-Keil grad student 2000 Emory
 (Functional analysis of the human enzyme UDP -galactose -4 -epimerase: Implications for epimerase -deficiency galactosemia.)
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Publications

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Thoden JB, Wohlers TM, Fridovich-Keil JL, et al. (2001) Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase. The Journal of Biological Chemistry. 276: 20617-23
Thoden JB, Wohlers TM, Fridovich-Keil JL, et al. (2001) Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active site. The Journal of Biological Chemistry. 276: 15131-6
Wohlers TM, Fridovich-Keil JL. (2000) Studies of the V94M-substituted human UDPgalactose-4-epimerase enzyme associated with generalized epimerase-deficiency galactosaemia. Journal of Inherited Metabolic Disease. 23: 713-29
Thoden JB, Wohlers TM, Fridovich-Keil JL, et al. (2000) Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase. Biochemistry. 39: 5691-701
Wohlers TM, Christacos NC, Harreman MT, et al. (1999) Identification and characterization of a mutation, in the human UDP-galactose-4-epimerase gene, associated with generalized epimerase-deficiency galactosemia. American Journal of Human Genetics. 64: 462-70
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