Grant P. Otto, Ph.D.
Affiliations: | 2003 | Columbia University, New York, NY |
Area:
Genetics, Molecular Biology, Cell Biology, Microbiology BiologyGoogle:
"Grant Otto"Parents
Sign in to add mentor| Richard H. Kessin | grad student | 2003 | Columbia | |
| (Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum.) | ||||
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Publications
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| Sharma D, Otto G, Warren E, et al. (2019) Gamma secretase orthologs are required for lysosomal activity and autophagic degradation in Dictyostelium discoideum, independent of PSEN (presenilin) proteolytic function. Autophagy |
| Otto GP, Sharma D, Williams RS. (2016) Non-Catalytic Roles of Presenilin Throughout Evolution. Journal of Alzheimer's Disease : Jad |
| Frej AD, Clark J, Roy CL, et al. (2016) The inositol-3-phosphate synthase biosynthetic enzyme has distinct catalytic and metabolic roles. Molecular and Cellular Biology |
| Ludtmann MH, Otto GP, Schilde C, et al. (2014) An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum. Journal of Cell Science. 127: 1576-84 |
| Otto GP, Nichols BJ. (2011) The roles of flotillin microdomains--endocytosis and beyond. Journal of Cell Science. 124: 3933-40 |
| Ludwig A, Otto GP, Riento K, et al. (2010) Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment. The Journal of Cell Biology. 191: 771-81 |
| Otto GP, Razi M, Morvan J, et al. (2010) A novel syntaxin 6-interacting protein, SHIP164, regulates syntaxin 6-dependent sorting from early endosomes. Traffic (Copenhagen, Denmark). 11: 688-705 |
| Tekinay T, Wu MY, Otto GP, et al. (2006) Function of the Dictyostelium discoideum Atg1 kinase during autophagy and development. Eukaryotic Cell. 5: 1797-806 |
| Ahras M, Otto GP, Tooze SA. (2006) Synaptotagmin IV is necessary for the maturation of secretory granules in PC12 cells. The Journal of Cell Biology. 173: 241-51 |
| Kosta A, Roisin-Bouffay C, Luciani MF, et al. (2004) Autophagy gene disruption reveals a non-vacuolar cell death pathway in Dictyostelium. The Journal of Biological Chemistry. 279: 48404-9 |