Christopher N. LaRock, Ph.D.
Affiliations: | Microbiology & Immunology | Emory University, Atlanta, GA | |
| 2012 | Microbiology | University of Washington, Seattle, Seattle, WA | |
| 2017 | Pediatrics | University of California, San Diego, La Jolla, CA |
Area:
Microbiology Biology, Immunology, BiochemistryWebsite:
larocklab.comGoogle:
"Christopher LaRock"Parents
Sign in to add mentor| Carleen M. Collins | grad student | University of Washington (Chemistry Tree) | ||
| Brad T. Cookson | grad student | 2012 | University of Washington | |
| (Mechanisms of inflammasome activation and inhibition during Yersinia infection.) | ||||
| Victor Nizet | post-doc | 2013-2017 | UCSD | |
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Publications
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| Do H, Li ZR, Tripathi PK, et al. (2024) Engineered probiotic overcomes pathogen defences using signal interference and antibiotic production to treat infection in mice. Nature Microbiology |
| Guerra S, LaRock C. (2024) Group A Streptococcus interactions with the host across time and space. Current Opinion in Microbiology. 77: 102420 |
| Wilde S, Dash A, Johnson A, et al. (2023) Detoxification of reactive oxygen species by the hyaluronic acid capsule of group A . Infection and Immunity. 91: e0025823 |
| LaRock DL, LaRock CN. (2023) Assessing Interleukin-1β Activation During Pyroptosis. Methods in Molecular Biology (Clifton, N.J.). 2641: 163-169 |
| Johnson AF, Sands JS, Trivedi KM, et al. (2023) Constitutive secretion of pro-IL-18 allows keratinocytes to initiate inflammation during bacterial infection. Plos Pathogens. 19: e1011321 |
| Everett MJ, Davies DT, Leiris S, et al. (2023) Chemical Optimization of Selective LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models. Acs Infectious Diseases |
| LaRock DL, Johnson AF, Wilde S, et al. (2022) Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes. Nature. 605: 527-531 |
| Johnson AF, LaRock CN. (2021) Antibiotic Treatment, Mechanisms for Failure, and Adjunctive Therapies for Infections by Group A . Frontiers in Microbiology. 12: 760255 |
| Wilde S, Johnson AF, LaRock CN. (2021) Playing With Fire: Proinflammatory Virulence Mechanisms of Group A . Frontiers in Cellular and Infection Microbiology. 11: 704099 |
| Atashgah RB, Ghasemi A, Raoufi M, et al. (2021) Restoring Endogenous Repair Mechanisms to Heal Chronic Wounds with a Multifunctional Wound Dressing. Molecular Pharmaceutics |