Peter J. Roach
Affiliations: | Indiana University, Bloomington, Bloomington, IN, United States |
Area:
Molecular Biology, Microbiology BiologyWebsite:
https://medicine.iu.edu/faculty/15102/roach-peter/Google:
"Peter John Roach"Children
Sign in to add trainee| De-Hua Yu | grad student | 2002 | Indiana University |
| Vincent S. Tagliabracci | grad student | 2010 | Indiana University |
| Sulochanadevi Baskaran | grad student | 2005-2010 | (Cell Biology Tree) |
| Sixin Jiang | grad student | 2011 | Indiana University |
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Publications
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| Ullman JC, Mellem KT, Xi Y, et al. (2024) Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders. Science Translational Medicine. 16: eadf1691 |
| Fastman NM, Liu Y, Ramanan V, et al. (2022) The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex. Cell Reports. 40: 111041 |
| Sun RC, Young LEA, Bruntz RC, et al. (2021) Brain glycogen serves as a critical glucosamine cache required for protein glycosylation. Cell Metabolism |
| Chown EE, Wang P, Zhao X, et al. (2020) GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease. Annals of Clinical and Translational Neurology |
| Tang B, Frasinyuk MS, Chikwana VM, et al. (2020) Discovery and development of small-molecule inhibitors of glycogen synthase. Journal of Medicinal Chemistry |
| Young LEA, Brizzee CO, Macedo JKA, et al. (2020) Accurate and sensitive quantitation of glucose and glucose phosphates derived from storage carbohydrates by mass spectrometry. Carbohydrate Polymers. 230: 115651 |
| Visuttijai K, Hedberg-Oldfors C, Thomsen C, et al. (2020) Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage. The Journal of Clinical Endocrinology and Metabolism. 105: 557-566 |
| Brewer MK, Uittenbogaard A, Austin GL, et al. (2019) Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion. Cell Metabolism |
| Burlet-Godinot S, Petit J-, Roach PJ, et al. (2019) New insights into the “Glycogenetic” hypothesis of sleep: brain glycogen availability affects REM-related theta rhythm providing a possible link with emotional memory mechanisms Sleep Medicine. 64 |
| Gentry MS, Guinovart JJ, Minassian BA, et al. (2018) Lafora disease offers a unique window into neuronal glycogen metabolism. The Journal of Biological Chemistry |