Edward Leadbetter

Affiliations: 
University of Connecticut, Storrs, CT, United States 
Area:
Microbiology Biology
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"Edward Leadbetter"
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Publications

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Vomhof-DeKrey EE, Yates J, Hägglöf T, et al. (2015) Cognate interaction with iNKT cells expands IL-10-producing B regulatory cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 12474-9
Lynch L, Michelet X, Zhang S, et al. (2015) Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue. Nature Immunology. 16: 85-95
Blackman MA, Yates JL, Spencer CM, et al. (2014) The Yin and Yang of inflammation. Current Molecular Medicine. 14: 1238-43
Siegmann N, Worbs D, Effinger F, et al. (2014) Invariant natural killer T (iNKT) cells prevent autoimmunity, but induce pulmonary inflammation in cystic fibrosis. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 34: 56-70
Vomhof-DeKrey EE, Yates J, Leadbetter EA. (2014) Invariant NKT cells provide innate and adaptive help for B cells. Current Opinion in Immunology. 28: 12-7
King IL, Amiel E, Tighe M, et al. (2013) The mechanism of splenic invariant NKT cell activation dictates localization in vivo. Journal of Immunology (Baltimore, Md. : 1950). 191: 572-82
Detre C, Keszei M, Garrido-Mesa N, et al. (2012) SAP expression in invariant NKT cells is required for cognate help to support B-cell responses. Blood. 120: 122-9
King IL, Fortier A, Tighe M, et al. (2012) Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner. Nature Immunology. 13: 44-50
Brigl M, Tatituri RV, Watts GF, et al. (2011) Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection. The Journal of Experimental Medicine. 208: 1163-77
Veerapen N, Leadbetter EA, Brenner MB, et al. (2010) Synthesis of a novel alpha-galactosyl ceramide haptenated-lipid antigen, a useful tool in demonstrating the involvement of iNKT cells in the production of antilipid antibodies. Bioconjugate Chemistry. 21: 741-7
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